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A5502
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Graeme J Gainsford et al.
Acta crystallographica. Section C, Crystal structure communications, 66(Pt 11), o527-o530 (2010-11-06)
The title compound, abbreviated as 5'ThiomethylImmA, is a potent inhibitor of methylthioadenosine phosphorylase [Singh et al. (2004). Biochemistry, 43, 9-18]. The synchrotron study reported here shows that the hydrochloride salt crystallizes with two independent, nearly superimposable, dications as a monohydrate
María Francisca Aguayo et al.
Plant science : an international journal of experimental plant biology, 205-206, 63-75 (2013-03-19)
Sorbitol is converted to fructose in Rosaceae species by SORBITOL DEHYDROGENASE (SDH, EC 1.1.1.14), especially in sink organs. SDH has also been found in non-Rosaceae species and here we show that the protein encoded by At5g51970 in Arabidopsis thaliana (L.)
Tomotake Morita et al.
Applied microbiology and biotechnology, 96(4), 931-938 (2012-06-23)
In order to develop novel glycolipid biosurfactants, Pseudozyma parantarctica JCM 11752(T), which is known as a producer of mannosylerythritol lipids (MEL), was cultivated using different sugar alcohols with the presence of vegetable oil. When cultivated in a medium containing 4
Baoguo Sun et al.
Journal of chromatography. A, 1271(1), 163-169 (2012-12-15)
Analytical methods were developed for a directed enzyme evolution research programme, which pursued high performance enzymes to produce high quality L-ribose using large scale biocatalytic reaction. A high throughput HPLC method with evaporative light-scattering detection was developed to test ribose
K J Bär et al.
Neurobiology of aging, 24(2), 333-338 (2002-12-25)
Increasing evidence suggests an interaction of oxidative stress and the formation of advanced glycation end products (AGE) in the onset and progression of Alzheimer's disease. We studied levels of pentosidine and N(epsilon)-(carboxymethyl)-lysine (CML) in serum and cerebrospinal fluid (CSF) of
Udi Jumhawan et al.
Journal of bioscience and bioengineering, 120(5), 555-561 (2015-04-29)
Development of authenticity screening for Asian palm civet coffee, the world-renowned priciest coffee, was previously reported using metabolite profiling through gas chromatography/mass spectrometry (GC/MS). However, a major drawback of this approach is the high cost of the instrument and maintenance.
Chang-wen Wu et al.
FEMS microbiology letters, 362(8), fnv040-fnv040 (2015-03-13)
PcPAF is a novel antifungal protein identified by our recent study, which is produced by a fungal strain Penicillium citrinum W1 isolated from a south-west Indian Ocean sediment sample. The present study identified glycine as a potential metabolite which increased
Barney A Geddes et al.
Microbiology (Reading, England), 158(Pt 8), 2180-2191 (2012-05-23)
The Sinorhizobium meliloti locus necessary for the utilization of erythritol as a sole carbon source, contains 17 genes, including genes that encode an ABC transporter necessary for the transport of erythritol, as well as the genes encoding EryA, EryB, EryC
Bo Feng et al.
BMC gastroenterology, 9, 99-99 (2009-12-31)
It is frequently important to identify the prognosis of fulminant hepatic failure (FHF) patients as this will influence patient management and candidacy for liver transplantation. Therefore, a novel scoring system based on metabonomics combining with multivariate logistic regression was developed
Udo F H Engelke et al.
Biochimica et biophysica acta, 1802(11), 1028-1035 (2010-07-06)
Sedoheptulose, arabitol, ribitol, and erythritol have been identified as key diagnostic metabolites in TALDO deficiency. Urine from 6 TALDO-deficient patients and TALDO-deficient knock-out mice were analyzed using ¹H-NMR spectroscopy and GC-mass spectrometry. Our data confirm the known metabolic characteristics in
Yu-bin Su et al.
Journal of proteome research, 14(3), 1612-1620 (2015-02-13)
Edwardsiella tarda, the causative agent of Edwardsiellosis, imposes medical challenges in both the clinic and aquaculture. The emergence of multidrug resistant strains makes antibiotic treatment impractical. The identification of molecules that facilitate or promote antibiotic efficacy is in high demand.
Anna Walter et al.
Neurobiology of aging, 25(10), 1299-1303 (2004-10-07)
Experimental and clinical studies give evidence for breakdown of membrane phospholipids during neurodegeneration. In the present study, we measured the levels of glycerophosphocholine (GPCh), phosphocholine (PCh), and choline, that is, water-soluble metabolites of phosphatidylcholine (PtdCho), in human cerebrospinal fluid (CSF).
G Ravi et al.
Glycoconjugate journal, 31(3), 247-258 (2014-03-20)
D-Ribitol, a five-carbon sugar alcohol, is an important metabolite in the pentose phosphate pathway; it is an integral part of riboflavin (vitamin B2) and cell wall polysaccharides in most Gram-positive and a few Gram-negative bacteria. Antibodies specific to D-ribitol were
Christoph Koentges et al.
Basic research in cardiology, 110(4), 36-36 (2015-05-13)
Sirtuin 3 (SIRT3) is a mitochondrial NAD(+)-dependent deacetylase that regulates energy metabolic enzymes by reversible protein lysine acetylation in various extracardiac tissues. The role of SIRT3 in myocardial energetics and in the development of mitochondrial dysfunction in cardiac pathologies, such
Takashi Abe et al.
Journal of neuroscience research, 70(3), 447-450 (2002-10-23)
To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8-hydroxyguanosine (8-OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and
L J Qu et al.
Journal of insect science (Online), 14, 166-166 (2014-11-05)
Radiation-induced sterile insect technique is a biologically based, environment-friendly method for the suppression or eradication of a number of insect pests. Although the basic mechanisms underlying the technology have been well studied, little is known about the cell responses in
Carrie L Brady et al.
International journal of systematic and evolutionary microbiology, 61(Pt 4), 932-937 (2010-05-25)
Eight yellow-pigmented, Gram-negative, rod-shaped, oxidase-negative, motile, facultatively anaerobic bacteria were isolated from onion seed in South Africa and from an onion plant exhibiting centre rot symptoms in the USA. The isolates were assigned to the genus Pantoea on the basis
Marcela P Cataldi et al.
Molecular therapy. Methods & clinical development, 17, 271-280 (2020-01-29)
Dystroglycanopathy, a subgroup of muscular dystrophies, is characterized by hypoglycosylation of α-dystroglycan (α-DG), which reduces its laminin-binding activity to extracellular matrix proteins, causing progressive loss of muscle integrity and function. Mutations in the fukutin-related protein (FKRP) gene are the most
Manuel Liebeke et al.
Methods in molecular biology (Clifton, N.J.), 815, 377-398 (2011-12-02)
The field of metabolomics has become increasingly important in the context of functional genomics. Together with other "omics" data, the investigation of the metabolome is an essential part of systems biology. Beside the analysis of human and animal biofluids, the
Zhi-xue Cheng et al.
Fish & shellfish immunology, 40(2), 524-530 (2014-08-15)
Streptococcus iniae infection has emerged as a serious fish health and economic problem in the global aquaculture operations. Current antibiotic options are few and possess severe practical limitations and potential adverse environmental impacts. The major factor contributing to the large
Thierry De Baere et al.
Journal of clinical microbiology, 40(10), 3867-3870 (2002-10-02)
A gram-negative Buttiauxella gaviniae-like organism (LBV449) was isolated from a urine sample of a patient suffering from urine bladder pathology and neurological problems. The isolate was positive for adonitol fermentation and L-arginine dihydrolase and negative for melibiose and L-ornithine decarboxylase.
Graeme J Gainsford et al.
Acta crystallographica. Section C, Crystal structure communications, 66(Pt 3), m65-m68 (2010-03-06)
The sodium salt of [immucillin-A-CO(2)H](-) (Imm-A), namely catena-poly[[[triaquadisodium(I)](mu-aqua)[mu-(1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol][triaquadisodium(I)][mu-(1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol]] tetrahydrate], {[Na(2)(C(12)H(13)N(4)O(6))(2)(H(2)O)(7)] x 4 H(2)O}(n), (I), forms a polymeric chain via Na(+)-O interactions involving the carboxylate and keto O atoms of two independent Imm-A molecules. Extensive N,O-H...O hydrogen bonding utilizing all water
Sandeep Deshmukh et al.
Journal of chromatography. A, 1388, 1-8 (2015-03-01)
Accurate quantitation of compounds in samples of biological origin is often hampered by matrix interferences one of which occurs in GC-MS analysis from the presence of highly abundant phosphate. Consequently, high concentrations of phosphate need to be removed before sample
Maofeng Jing et al.
Plant cell reports, 34(7), 1263-1280 (2015-04-24)
Few proteomic studies have focused on the plant- Phytophthora interactions, our study provides important information regarding the use of proteomic methods for investigation of the basic mechanisms of plant-Phytophthora interactions. Phytophthora sojae is a fast-spreading and devastating pathogen that is
S H Moolenaar et al.
NMR in biomedicine, 14(3), 167-176 (2001-05-18)
In vivo NMR spectroscopy was performed on the brain of a patient with a leukoencephalopathy, revealing unknown resonances between 3.5 and 4.0 ppm. In addition, urine and CSF of the patient were measured using high-resolution NMR spectroscopy. Also in these
Beatrice Bocca et al.
Annali dell'Istituto superiore di sanita, 41(2), 197-203 (2005-10-26)
The haematic concentration of 26 metals and the oxidative damage in 60 patients (20 males and 40 females) affected by Alzheimer's disease and 44 healthy individuals (33 males and 11 females) were compared. In patients, the following significant (p <
A C McWhorter et al.
Journal of clinical microbiology, 29(7), 1480-1485 (1991-07-01)
In 1985 the vernacular name Enteric Group 90 was coined for a small group of strains that had been referred to our laboratory as probable strains of Salmonella but did not agglutinate in Salmonella typing antisera. By DNA-DNA hybridization (hydroxyapatite
Yan-Mei Ma et al.
Fish & shellfish immunology, 45(2), 414-421 (2015-05-11)
Streptococcus iniae seriously affects the intensive farming of tilapias. Much work has been conducted on prevention and control of S. iniae infection, but little published information on the metabolic response is available in tilapias against the bacterial infection, and no metabolic
Dandan Duan et al.
Chemosphere, 251, 126368-126368 (2020-03-17)
Mangrove sediments act as an important natural sink and a secondary source for trace metals. The main objective of this study was to investigate metal contamination and its relationship to mangrove-derived carbohydrates in mangrove sediments. Sixteen metals (Be, V, Cr
Anders Østergaard Madsen et al.
The journal of physical chemistry. A, 115(26), 7794-7804 (2011-06-15)
X-ray diffraction data of high quality measured to high resolution on crystals of the two pentitol epimers ribitol (centric) and xylitol (acentric) at 101, 141, and 181 K and data on the two compounds previously recorded at 122 K have
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