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Dongxia Hou et al.
PloS one, 10(11), e0142442-e0142442 (2015-11-12)
Trophoblasts (TR) are specialized cells of the placenta and play an important role in embryo implantation. The in vitro culture of trophoblasts provided an important tool to investigate the mechanisms of implantation. In the present study, porcine trophoblast cells were
Manish M Khandagale et al.
Journal of chromatography. A, 1356, 180-187 (2014-07-09)
The solvent dependency of the detection response is a major limitation of corona-charged aerosol detection (C-CAD). The present study empirically investigates the utility of temperature and flow-rate gradients to overcome solvent gradient limitations of C-CAD. In preliminary flow-injection investigations, it
Ai-Li Sun
The Analyst, 140(23), 7948-7954 (2015-10-27)
A new electrochemical immunosensor with signal enhancement was designed for sensitive detection of disease-related protein (human carbohydrate antigen 19-9, CA 19-9 used in this case). The assay was carried out on a capture antibody-modified screen-printed carbon electrode with a sandwich-type
Kun Qian et al.
Journal of economic entomology, 106(2), 979-987 (2013-06-22)
A commercial vinegar product (ChinKiang) was found to be highly attractive to adult house flies, Musca domestica L. Field experiments on a Nebraska dairy demonstrated that traps baited with vinegar and brown sugar captured more house flies than those baited
Sandra Varum et al.
Cell stem cell, 24(4), 637-653 (2019-04-06)
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiation and progression. Melanoma arises from melanocytes that originate during development from neural crest stem cells (NCSCs). Here, we identified the transcription factor Yin Yang 1 (Yy1) as an
Konstantina C Fylaktakidou et al.
ChemMedChem, 6(1), 153-168 (2010-11-26)
Polyphosphorylated and perphosphorylated hexopyranose monosaccharides and disaccharides were synthesized from parent or partially protected carbohydrates as potential allosteric effectors of hemoglobin. A study toward the construction of seven- and eight-membered cyclic pyrophosphates was also performed on the sugars which had
Hasan Imam et al.
Pakistan journal of biological sciences : PJBS, 16(23), 1796-1800 (2014-02-11)
Previously it was reported elsewhere that Lawsonia inermis have anti-inflammatory and analgesic effect in experimental animals. The in vitro porcine alpha amylase inhibitory effect was investigated of this plant methanolic extracts and consequently hypoglycemic effect by quantitatively determining the maltose
Sabrina Haag et al.
Journal of immunology (Baltimore, Md. : 1950), 194(6), 2539-2550 (2015-02-13)
Rheumatoid arthritis (RA) is associated with amino acid variants in multiple MHC molecules. The association to MHC class II (MHC-II) has been studied in several animal models of RA. In most cases these models depend on T cells restricted to
Yellela S R Krishnaiah et al.
International journal of pharmaceutics, 475(1-2), 110-122 (2014-08-05)
The effect of process variability on physicochemical characteristics and in vitro performance of qualitatively (Q1) and quantitatively (Q2) equivalent generic acyclovir topical dermatological creams was investigated to develop a matrix of standards for determining their in vitro bioequivalence with reference
Xiaobin Yang et al.
European journal of pharmacology, 765, 209-216 (2015-08-25)
This work aimed to investigate the therapeutic effect of curcumin on sublesional bone loss induced by spinal cord injury (SCI) in rats. SCI model in this work was generated in rats by surgical transaction of the cord at the T10-12
Yuzo Yamada et al.
International journal of food microbiology, 125(1), 15-24 (2008-01-18)
Taxonomic studies of acetic acid bacteria were historically surveyed. The genus Acetobacter was first introduced in 1898 with a single species, Acetobacter aceti. The genus Gluconobacter was proposed in 1935 for strains with intense oxidation of glucose to gluconic acid
Jincui Huang et al.
Journal of proteome research, 14(3), 1335-1349 (2015-01-30)
Secretory immunoglobulin A (sIgA) is a major glycoprotein in milk and plays a key role in mediating immune protection of the gut mucosa. Although it is a highly glycosylated protein, its site-specific glycosylation and associated glycan micro-heterogeneity have still not
Kalpana Mandal et al.
Nature communications, 5, 5749-5749 (2014-12-11)
Cells sense and respond to their mechanical environment by exerting forces on their surroundings. The way forces are modulated by extra-cellular matrix (ECM) properties plays a key role in tissue homoeostasis. Using highly resolved micropatterns that constrain cells into the
Sevgi Turker et al.
Biochimica et biophysica acta, 1838(12), 3088-3096 (2014-09-10)
Epilepsy is characterized by disruption of balance between cerebral excitation and inhibition, leading to recurrent and unprovoked convulsions. Studies are still underway to understand mechanisms lying epileptic seizures with the aim of improving treatment strategies. In this context, the research
Abdulselam Ertas et al.
Pharmaceutical biology, 53(3), 334-339 (2014-10-22)
In Turkey, Veronica species (Plantaginaceae) have been used as a diuretic and for wound healing in traditional medicine. To examine the fatty acid and essential oil profiles, the antioxidant, anticholinesterase, antimicrobial, and DNA damage effects of Veronica thymoides P.H. Davis
Lynne Gaffikin et al.
Obstetrical & gynecological survey, 58(8), 543-550 (2003-07-30)
Developing countries often lack the necessary resources to use the Papanicolaou (Pap) smear as a screening tool for cervical abnormalities. Because the burden of cervical cancer is highest in such low-resource settings, alternative techniques have been sought. Recently, interest in
Yang Shu et al.
Journal of chromatography. A, 1390, 50-61 (2015-03-17)
Three cyclofructan-based, two glycopeptide-based, and one zwitterionic column used in the HILIC mode were assessed within a graphical framework based on different functional characteristics contributing to selectivity. The characteristics of these six HILIC columns are put in the perspective of
Krasimira T Petrova et al.
Carbohydrate research, 417, 66-71 (2015-10-04)
A library of 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-1,2,3-triazoles have been investigated for their antibacterial, antifungal and cytotoxic activities. Most of the target compounds showed good inhibitory activity against a variety of clinically and food contaminant important microbial pathogens. In particular, 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-4-(4-pentylphenyl)-1,2,3-triazole (5) was highly
Michal Čáp et al.
Cell cycle (Georgetown, Tex.), 14(21), 3488-3497 (2015-11-15)
Colonies of Saccharomyces cerevisiae laboratory strains pass through specific developmental phases when growing on solid respiratory medium. During entry into the so-called alkali phase, in which ammonia signaling is initiated, 2 prominent cell types are formed within the colonies: U
Jingjing Meng et al.
Bio-protocol, 6(10) (2016-05-20)
Transepithelial Electrical Resistance (TER) measurement is a reliable and efficient method to quantify the permeability of barrier forming cells such as epithelial cells. Measuring the permeability of the epithelial cells will help the researchers to investigate the barrier function of
Xing-Yu Xu et al.
Fitoterapia, 101, 218-223 (2015-01-27)
Two new sesquiterpene lactone dimers, neojaponicone B (1) and inulanolide E (2) along with five known sesquiterpene lactone dimers (3-7, resp.) were isolated from the aerial parts of Inula japonica Thunb. The chemical structures of 1 and 2 were elucidated
Zhaozhou Li et al.
Journal of pharmaceutical and biomedical analysis, 98, 210-220 (2014-06-20)
The molecularly imprinted polymers (MIPs) were prepared by an oxidation-reduction polymerization system using a non-covalent molecularly imprinting strategy with hypericin as the template, acrylamide as the functional monomer and pentaerythritol triacrylate as the cross-linker in the porogen of acetone. The
Yifeng Xue et al.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 12(3), 253-260 (2014-06-09)
To evaluate the immunomodulatory properties of human amniotic mesenchymal stromal cells. Human amniotic mesenchymal stromal cells were isolated, characterized by flow cytometry, cultured in vitro, and evaluated in allogeneic and xenogeneic mixed lymphocyte reactions. The proliferation of T cells and
Gemma Buron-Moles et al.
Journal of proteomics, 114, 136-151 (2014-12-03)
Apples are subjected to both abiotic and biotic stresses during the postharvest period, which lead to large economic losses worldwide. To obtain biochemical insights into apple defense response, we monitored the protein abundance changes (proteome), as well as the protein
Tie Yi Kiew et al.
International journal of pharmaceutics, 484(1-2), 115-123 (2015-03-01)
While the supersaturation generation capability of amorphous nanopharmaceuticals (NPs) in their aqueous suspension form has been well established, their supersaturation generation is adversely affected after drying. Herein we investigated the effects of freeze drying on the supersaturation generation capability of
Hayrettin O Gülcan et al.
Archiv der Pharmazie, 348(1), 55-61 (2015-01-13)
The current structure-activity relationship of profens (i.e., 2-arylpropionic acid derivatives, a class of non-steroidal anti-inflammatory drugs) discusses the importance of α-monomethyl substitution on these compounds, since the activities obtained through their corresponding arylacetic acid derivatives (i.e., α-demethylated derivatives) or α,α-dimethyl-substituted
Jae-Yup Kim et al.
ACS nano, 9(11), 11286-11295 (2015-10-03)
Copper-indium-selenide (CISe) quantum dots (QDs) are a promising alternative to the toxic cadmium- and lead-chalcogenide QDs generally used in photovoltaics due to their low toxicity, narrow band gap, and high absorption coefficient. Here, we demonstrate that the photovoltaic performance of
Imène Chaïr-Yousfi et al.
International immunopharmacology, 25(1), 19-29 (2015-01-21)
Lung injury and respiratory distress syndrome are frequent symptoms observed in the most severe cases of scorpion envenomation. The uncontrolled transmigration of leukocyte cells into the lung interstitium and alveolar space and pulmonary edema may be the cause of death.
Jessica Karlsson et al.
PloS one, 9(7), e103589-e103589 (2014-07-26)
In addition to their effects upon prostaglandin synthesis, the non-steroidal anti-inflammatory drugs ibuprofen and flurbiprofen inhibit the metabolism of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) by cyclooxygenase-2 (COX-2) and fatty acid amide hydrolase (FAAH), respectively. Here, we investigated whether
Marcel Prax et al.
Journal of microbiological methods, 118, 176-181 (2015-10-13)
Sodium polyanethol sulfonate (SPS) is an anionic detergent with a broad range of activities and applications. While studying the excretion of cytoplasmic proteins in Staphylococcus aureus SPS was used as cell lysis inhibitor. When investigating the protein pattern of culture
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