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Mangala Lakshmi Ragavan et al.
Current microbiology, 77(10), 2821-2830 (2020-06-28)
The present study investigates the therapeutic properties of probiotic yeasts viz. Yarrowia lipolytica VIT-MN01, Kluyveromyces lactis VIT-MN02, Lipomyces starkeyi VIT-MN03, Saccharomycopsis fibuligera VIT-MN04 and Brettanomyces custersianus VIT-MN05. The antimutagenic activity of probiotic yeasts against the mutagens viz. Benzo[a]pyrene (B[a]P), and
Robert Laumbach et al.
Journal of environmental monitoring : JEM, 11(1), 153-159 (2009-01-13)
Diesel exhaust (DE) is a significant source of air pollution that has been linked to respiratory and cardiovascular morbidity and mortality. Many components in DE, such as polycyclic aromatic hydrocarbons, are present in the environment from other sources. 1-Nitropyrene appears
K Hayakawa
Biomedical chromatography : BMC, 14(6), 397-405 (2000-09-26)
Nitropolycyclic aromatic hydrocarbons (NPAHs), which are known to be carcinogenic and/or mutagenic, are considered to be one of the air pollutants that cause lung cancer. In the last two decades, a number of sensitive and selective methods have been developed
R Shapiro et al.
Chemical research in toxicology, 11(4), 335-341 (1998-05-05)
While the one-ring amine aniline (AN) has only slight genetic activity, the polycyclic aromatic amines 2-aminofluorene (AF) and 1-aminopyrene (AP) are significant mutagens and carcinogens. Moreover, the bulkier AP is more mutagenic per adduct than AF in the tetracycline-resistance gene
M A Belisario et al.
Toxicology, 108(1-2), 101-108 (1996-04-15)
Nitroarenes are environmental contaminants produced during incomplete combustion processes. Nitroreduction, the most important pathway of nitroarene toxification, occurs mainly in the liver and intestine. In the present study, we show that human red cells may also possess the metabolic competence
O Wongwattanasathien et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(4), 1045-1051 (2010-01-27)
The mutagenicity of dichloromethane, methanol and water extracts of Antigonon leptopus Hook. & Arn., Curcuma sessilis Gage, Hibiscus rosa-sinensis Linn., Ixora coccinea Linn., Millingtonia hortensis Linn., Nelumbo nucifera Gaertn., Plumeria obtusa Linn., Punica granatum Linn., Rhinacanthus nasutus ((Linn.) Kurz.) and
Bert Willis et al.
Bioorganic & medicinal chemistry letters, 19(17), 4974-4979 (2009-08-05)
A novel conjugate of Hoechst 33258, pyrene and neomycin was synthesized and examined for its binding and stabilization of A-T rich DNA duplexes using spectroscopic and viscometric techniques. The conjugate, containing three well known ligands that bind nucleic acids albeit
Tianzhu Zhou et al.
Nature communications, 11(1), 2077-2077 (2020-05-01)
Flexible reduced graphene oxide (rGO) sheets are being considered for applications in portable electrical devices and flexible energy storage systems. However, the poor mechanical properties and electrical conductivities of rGO sheets are limiting factors for the development of such devices.
Kui Zeng et al.
Environmental toxicology and chemistry, 23(6), 1400-1407 (2004-09-21)
1-Aminopyrene (1-AP) is an environmental mutagen and a metabolite of 1-nitropyrene (1-NO2P). On light irradiation, 1-AP transforms into oxidation products with a half-life of 7.1 min in 10% methanolic buffer. The presence of DNA or free-radical/ singlet oxygen scavengers 1,4-dithiothreitol
Alison E Mahan et al.
Journal of immunological methods, 417, 34-44 (2014-12-20)
The N-glycan of the IgG constant region (Fc) plays a central role in tuning and directing multiple antibody functions in vivo, including antibody-dependent cellular cytotoxicity, complement deposition, and the regulation of inflammation, among others. However, traditional methods of N-glycan analysis
Oksana Yosypchuk et al.
Analytical and bioanalytical chemistry, 404(3), 693-699 (2012-06-15)
A high-performance liquid chromatographic method with electrochemical detection (HPLC-ED) at a boron-doped diamond film electrode with preliminary separation and preconcentration by solid-phase extraction (SPE) has been developed for the determination of 1-hydroxypyrene (1-HP) in human urine. 1-HP is among the
Johan Øvrevik et al.
Toxicology letters, 219(2), 125-132 (2013-03-06)
We have previously observed that 1-nitropyrene (1-NP) and its amine metabolite 1-aminopyrene (1-AP) induce differential chemokine responses in human bronchial epithelial cells (BEAS-2B) characterized by maximum responses for CXCL8 (IL-8) and CCL5 (RANTES), respectively. In the present study, we further
Maria Nowacka et al.
Materials (Basel, Switzerland), 13(20) (2020-10-15)
Hybrid polymers containing pyrene (Py) units bound to linear poly(silsesquioxane) (LPSQ) chains through flexible linkers containing heteroatoms (S, N, O) (LPSQ-triazole-Py and LPSQ-amide-Py) exhibit intense fluorescence emission, both in very diluted solutions (c = 10-8 mol/L) and in the solid
Johan Øvrevik et al.
Environmental toxicology and pharmacology, 35(2), 235-239 (2013-01-26)
1-nitropyrene (1-NP), a common PAH in diesel exhaust, and its amine metabolite 1-aminopyrene (1-AP) induce distinctly different chemokine-responses in bronchial epithelial cells (BEAS-2B) characterized by increases in CXCL8 and CCL5, respectively. Tumor necrosis factor-α converting enzyme (TACE), which cleaves membrane-bound
A Ferancová et al.
Bioelectrochemistry (Amsterdam, Netherlands), 67(2), 191-197 (2005-08-27)
The aim of this work was voltammetric determination of 1-aminopyrene and 1-hydroxypyrene using carbon paste electrodes modified with cyclodextrin derivatives and double stranded deoxyribonucleic acid (dsDNA). The detection schemes based on a preconcentration and differential pulse voltammetric (DPV) determination at
Sofja Tshepelevitsh et al.
Analytica chimica acta, 1132, 123-133 (2020-09-28)
Lipophilicity, usually expressed as octanol-water partition coefficient (logPo/w), is an important property in biomedical research, drug design and technology. However, high logPo/w values of complex hydrogen-bonding molecules are not easy to measure or calculate. Exemplary problematic molecules are prospective active
Z Gu et al.
Biochemistry, 38(33), 10843-10854 (1999-08-18)
Solution structural studies have been undertaken on the aminopyrene-C(8)-dG ([AP]dG) adduct in the d(C5-[AP]G6-C7). d(G16-A17-G18) sequence context in an 11-mer duplex with dA opposite [AP]dG, using proton-proton distance and intensity restraints derived from NMR data in combination with distance-restrained molecular
Dina Mukha et al.
ChemSusChem, 13(10), 2684-2692 (2020-02-19)
The construction of bias- and donor-free photobioelectrochemical cells for the generation of light-triggered electrical power is presented. The developed oxygen reduction biocathodes are based on bilirubin oxidase (BOD) that originates from Myrothecium verrucaria (MvBOD) and a thermophilic Bacillus pumilus (BpBOD).
Junkuo Gao et al.
Dalton transactions (Cambridge, England : 2003), 41(39), 12185-12191 (2012-08-30)
A novel pyrene covalently-attached polyoxometalate (POM) hybrid has been synthesized and fully characterized. The attractive electronic and photophysical properties of pyrene derivatives make the hybrid promising for studying and understanding electron transfer mechanisms in organic-functionalized POMs. The hybrid has an
Susan Huyck et al.
Journal of exposure science & environmental epidemiology, 20(7), 650-655 (2010-05-06)
Biomonitoring of exposures to toxins is an important tool for monitoring public health and safety. Using this tool, exposures are typically measured by the collection of biological specimens such as blood and urine samples. Urine sampling represents a more convenient
Carole Di Giorgio et al.
Journal of environmental quality, 39(2), 558-567 (2010-02-24)
The impact of industrial, rural, and urban activities on two runnels (B1, B2, and B3 from Beausset runnel and V1 and V2 from Vallat du Ceinturon runnel) located in the Palun marshes (Berre lagoon, France) was evaluated by analyzing 16
Li Yang et al.
Nanoscale, 12(11), 6233-6238 (2020-03-07)
Chiral nanomaterials with circularly polarized luminescence (CPL) have attracted increasing attention as they show improved luminous efficiency and high contrast images in optical displays. Herein, nanotwisted fibers with bright full-color CPL are developed through the co-assembly of chiral phenylalanine derived
Hua Miao et al.
British journal of pharmacology, 177(15), 3415-3435 (2020-03-29)
Increasing evidence has indicated that the high risk of cardiovascular disease in chronic kidney disease (CKD) patients cannot be sufficiently explained by classic risk factors. Based on the least absolute shrinkage and selection operator method, we identified significantly altered renal
Jingjing Xue et al.
Science (New York, N.Y.), 371(6529), 636-640 (2021-02-06)
The band edges of metal-halide perovskites with a general chemical structure of ABX3 (A, usually a monovalent organic cation; B, a divalent cation; and X, a halide anion) are constructed mainly of the orbitals from B and X sites. Hence
Rakesh Chopra et al.
Analytica chimica acta, 864, 55-63 (2015-03-04)
A pyrene-based small molecular weight probe, exhibiting aggregation enhanced excimer emission has been synthesized. The crystalline emissive form detects 2,4,6-trinitrophenol (picric acid) at parts-per-billion concentration in solution and as low as 0.46 attogram in direct contact mode, operating predominantly in
Stephen I N Ekunwe et al.
International journal of environmental research and public health, 2(1), 58-62 (2006-05-20)
Over the past several years, a great deal of interest has been focused on the harmful effects of ultraviolet (UV) radiation to human skin. UV light has been implicated in aging, sunburn and skin cancer. Few studies, however, have been
Effect of river humic acid on 1-aminopyrene ecotoxicity in a dynamic solar photolysis process.
H M Hwang et al.
Bulletin of environmental contamination and toxicology, 72(5), 1059-1066 (2004-07-23)
Toshimitsu Onduka et al.
Chemosphere, 169, 596-603 (2016-12-03)
Photo-induced toxicity is an important phenomenon in ecotoxicology because sunlight reaches many organisms in their natural habitats. To elucidate whether sunlight enhances the toxicity of nitro-polycyclic aromatic hydrocarbons (nitro-PAHs), the acute toxicities of 10 nitro-PAHs and the related compound 1-nitropyrene
Tian Jin et al.
Talanta, 200, 242-248 (2019-05-01)
Due to severely overlapping emission and or/ excitation spectra of polycyclic aromatic hydrocarbons (PAHs), the specifically recognizing PAHs by the fluorescent technique is still a challenge. Here, synthesized Ag@SiO2 nanoparticles with 40 ± 4 nm Ag core and 7 ± 1 nm SiO2 shell performing as
P D Josephy et al.
Mutation research, 429(2), 199-208 (1999-10-20)
The mutagenic actions of many chemicals depend on the activities of bacterial "mutagenesis proteins", which allow replicative bypass of DNA lesions. Genes encoding these proteins occur on bacterial chromosomes and plasmids, often in the form of an operon (such as
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