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Reza Ojani et al.
Talanta, 81(4-5), 1522-1528 (2010-05-06)
In this work for first time, the electrocatalytic oxidations of some cephalosporins were carried out by poly(o-anisidine)/SDS/Ni modified carbon paste electrode using cyclic voltammetry, chronoamperometry and chronocoulometry methods. At first, poly(o-anisidine) was formed by cyclic voltammetry in monomer solution containing
Marie Stiborová et al.
Mutation research, 500(1-2), 49-66 (2002-03-14)
2-Methoxyaniline (o-anisidine) is a urinary bladder carcinogen in both mice and rats. Since the urinary bladder contains substantial peroxidase activity, we investigated the metabolism of this carcinogen by prostaglandin H synthase (PHS), a prominent enzyme in the urinary bladder, and
Karel Naiman et al.
Toxicological sciences : an official journal of the Society of Toxicology, 127(2), 348-359 (2012-03-10)
2-Methoxyaniline (o-anisidine) is an industrial and environmental pollutant causing tumors of urinary bladder in rodents. Here, we investigated the formation and persistence of DNA adducts in the Wistar rat. Using the (32)P-postlabeling method, three o-anisidine-derived DNA adducts were found in
Karel Naiman et al.
Mutation research, 726(2), 160-168 (2011-09-29)
N-(2-Methoxyphenyl)hydroxylamine is a component in the human metabolism of two industrial and environmental pollutants and bladder carcinogens, viz. 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole), and it is responsible for their genotoxicity. Besides its capability to form three deoxyguanosine adducts in DNA
Xin-Gui Li et al.
Small (Weinheim an der Bergstrasse, Germany), 4(8), 1201-1209 (2008-07-31)
Novel copolymer nanoparticles with inherent self-stability, narrow size distribution, and high electrical conductivity are facilely and productively synthesized by the oxidative precipitation polymerization of 5-sulfonic-2-anisidine and aniline in acidic medium without any external stabilizer. The structures of the copolymer particles
Karel Naiman et al.
Chemical research in toxicology, 21(8), 1610-1621 (2008-07-16)
We investigated the ability of hepatic microsomes from rat and rabbit to metabolize 2-methoxyaniline (o-anisidine), an industrial and environmental pollutant and a bladder carcinogen for rodents. Using HPLC combined with electrospray tandem mass spectrometry, we determined that o-anisidine is oxidized
Karel Naiman et al.
Neuro endocrinology letters, 31 Suppl 2, 36-45 (2010-12-29)
N-(2-methoxyphenyl)hydroxylamine is a human metabolite of two industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Metabolism of N-(2-methoxyphenyl)hydroxylamine by rat hepatic microsomes and identification of the major microsomal enzymes participating in this process are aims of
Helena Dracínska et al.
Neuro endocrinology letters, 27 Suppl 2, 9-13 (2006-12-13)
The detoxifying metabolism of a potent rodent carcinogen, 2-nitroanisole (2-NA) by human, rabbit and rat cytochromes P450 (P450) was investigated. Comparison between P450s of experimental animals and humans is essential for the extrapolation of animal carcinogenicity data to the human
E Roemer et al.
Regulatory toxicology and pharmacology : RTP, 70 Suppl 1, S2-14 (2014-12-17)
This publication introduces a series of six other publications describing the toxicological assessment of kretek cigarettes, i.e., cigarettes characterized primarily by the use of a significant amount of cloves as an ingredient added to the tobacco. This paper presents background
Helena Rýdlová et al.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 149(2), 441-447 (2006-04-08)
2-Methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole) are important pollutants and potent carcinogens for rodents. o-Anisidine is oxidized by microsomes of rats and rabbits to N-(2-methoxyphenyl)hydroxylamine that is also formed as the reduction metabolite of o-nitroanisole. o-Anisidine is a promiscuity substrate of
Marie Stiborová et al.
Carcinogenesis, 25(5), 833-840 (2004-01-20)
2-Nitroanisole (2-NA) is an important industrial pollutant and a potent bladder carcinogen for rodents. The mechanism of its carcinogenicity was investigated in this study. Here we have used two independent methods, (32)P-post-labeling and (3)H-labeled 2-NA, to show that 2-NA binds
Parimal Routh et al.
Biophysical chemistry, 143(3), 145-153 (2009-06-02)
Biomolecular hybrids of a conducting polymer [poly(o-methoxy aniline) (POMA)] and RNA are prepared at the three different compositions by mixing aqueous solutions of diethyl, 2-hydroxy ethyl, ammonium salt of RNA (type IX from Torula Yeast) and POMA (ES, emeraldine salt;
Paulo A Ribeiro et al.
Journal of nanoscience and nanotechnology, 6(5), 1396-1404 (2006-06-24)
Neutron reflectivity measurements were used to investigate the thermal stability of layer-by-layer (LBL) films of poly(o-methoxyaniline) (POMA), which was probed by increasing the temperature up to 80 degrees C of a D2O solution in contact with the LBL films. The
Marie Stiborová et al.
International journal of cancer, 116(5), 667-678 (2005-04-14)
2-methoxyaniline (o-anisidine) is an industrial and environmental pollutant and a bladder carcinogen for rodents. The mechanism of its carcinogenicity was investigated with 2 independent methods, 32P-postlabeling and 14C-labeled o-anisidine, to show that o-anisidine binds covalently to DNA in vitro after
Birgitta Kütting et al.
International journal of hygiene and environmental health, 212(3), 298-309 (2008-09-16)
The population-based cross-sectional study including 1004 Bavarian volunteers aged 3 up to 84 years (median: 42 years) was aimed to quantify the internal burden of monocyclic arylamines in the general population and to yield reference values. Participants were asked to
o-Anisidine hydrochloride.
Report on carcinogens : carcinogen profiles, 11, III17-III18 (2004-01-01)
Ning Wang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(19), 6049-6054 (2012-03-29)
The recent development of 1D nanomaterials of controllable size, composition, and structure has opened up enormous possibilities for engineering catalysts with enhanced activity and selectivity. Herein, we report a one-step strategy for the fabrication of versatile silver nanomaterials. Tailored structures
Xin-Gui Li et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(18), 4573-4581 (2009-03-20)
The highest Hg-ion adsorbance so far, namely up to 2063 mg g(-1), has been achieved by poly(aniline-co-5-sulfo-2-anisidine) nanosorbents. Sorption of Hg ions occurs mainly by redox and chelation mechanisms (see scheme), but also by ion exchange and physisorption.Poly(aniline (AN)-co-5-sulfo-2-anisidine (SA))
M Mazur
The European physical journal. E, Soft matter, 22(1), 67-75 (2007-03-06)
We report on chemical polymerization of two aniline derivatives - 2-methylaniline and 2-methoxyaniline -- in a two-phase water/pentane system. We have found that poly(2-methylaniline) is produced in form of an amorphous material regardless of the fact whether the monomer is
Rosario Rodriguez-Arnaiz et al.
Mutation research, 514(1-2), 193-200 (2002-01-30)
Several structurally related anisidine and dibenzanthracene isomers were evaluated for genotoxic effects in the somatic w/w+ assay of Drosophila melanogaster employing insecticide-susceptible (IS) and insecticide-resistant (IR) tester strains. In addition, and in order to find whether or not at the
Andrzej Sapota et al.
International journal of occupational medicine and environmental health, 16(4), 351-357 (2004-02-18)
The principal commercial use of o-anisidine is believed to be as an intermediate in the manufacture of dyes. It has also been reported to be an intermediate in the manufacture of synthetic guaiacol and its derivatives. o-Anisidine is an urinary
Arnab Dawn et al.
The journal of physical chemistry. B, 110(37), 18291-18298 (2006-09-15)
A novel nano-biocomposite of silver and poly(o-methoxy aniline) (POMA)/DNA hybrid has been prepared by adding DNA solution to an aqueous solution of POMA (emeraldine base, EB) and AgNO(3) mixture. The mixture was aged for 10 days and was freeze-dried to
Muhammad Sirajuddin et al.
European journal of medicinal chemistry, 84, 343-363 (2014-07-19)
Fourteen new organotin(IV) complexes with general formula R2SnL2 or R3SnL where R = CH3, C2H5, C4H9, C6H5, C6H11, CH2-C6H5, C(CH3)3, C8H17 and L = N-[(2-methoxyphenyl)]-4-oxo-4-[oxy]butanamide were synthesized and characterized by elemental analyses, FT-IR, NMR ((1)H, (13)C and (119)Sn), mass spectrometry
o-Anisidine and its hydrochloride.
Report on carcinogens : carcinogen profiles, 12, 43-45 (2011-08-11)
D Sangamithirai et al.
Materials science & engineering. C, Materials for biological applications, 91, 512-523 (2018-07-24)
Dopamine (DA) and Folic acid (FA) are co-existing compounds in biological fluids that plays a vital role in central nervous system and human metabolism. DA is an important neurotransmitter in the brain's neural circuits and its diminution often results in
Nara C de Souza et al.
Journal of nanoscience and nanotechnology, 4(5), 548-552 (2004-10-27)
The dynamic scale theory and fractal concepts are employed in the characterization of surface morphological properties of layer-by-layer (LBL) films from poly(o-methoxyaniline) (POMA) alternated with poly(vinyl sulfonic acid) (PVS). The fractal dimensions are found to depend on the procedures to
P Santhosh et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(7), 1427-1439 (2003-04-26)
UV-visible spectroelectrochemical studies on copolymerization of diphenylamine (DPA) with ortho-methoxy aniline (OMA) were carried out for different feed ratios of DPA and OMA using indium tin oxide (ITO)-coated glass as working electrode. The UV-visible spectra show clear dependencies on the
o-Anisidine hydrochloride.
Report on carcinogens : carcinogen profiles, 10, 16-17 (2004-08-20)
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