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M Krause et al.
International journal of andrology, 35(3), 424-436 (2012-05-23)
Today, topical application of sunscreens, containing ultraviolet-filters (UV-filters), is preferred protection against adverse effects of ultraviolet radiation. Evidently, use of sunscreens is effective in prevention of sunburns in various models. However, evidence for their protective effects against melanoma skin cancer
Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid.
Parekh J, et al.
J. Serb. Chem. Soc., 70(10), 1155-1155 (2005)
Dudu Demir et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 40(6), 391-395 (2012-07-12)
Prophenoloxidase (PPO) was purified from Galleria mellonella L. A 67-fold purification of the proenzyme with 352% yield was achieved by using a Sepharose 4B-L-tyrosine-p-amino benzoic acid affinity column. The purified enzyme was migrated as a single band on SDS-polyacrylamide gel
A Szewczuk et al.
Clinica chimica acta; international journal of clinical chemistry, 84(1-2), 19-26 (1978-03-01)
By the phthaloyl method less toxic and readily soluble gamma-L-glutamyl-p-aminobenzoic acid was synthesized. This substance was used as a substrate for gamma-glutamyltranspeptidase activity assay in blood serum and urine. Close correlation was shown between the results obtained with the new
Seth Dixon et al.
Journal of medicinal chemistry, 49(25), 7413-7426 (2006-12-08)
4-Amino-4-deoxychorismate synthase (ADCS) catalyzes the first step in the conversion of chorismate into p-aminobenzoate, which is incorporated into folic acid. We aim to discover compounds that inhibit ADCS and serve as leads for a new class of antimicrobial compounds. This
Joonhoon Kim et al.
Frontiers in bioengineering and biotechnology, 8, 612832-612832 (2021-02-16)
An oleaginous yeast Rhodosporidium toruloides is a promising host for converting lignocellulosic biomass to bioproducts and biofuels. In this work, we performed multi-omics analysis of lignocellulosic carbon utilization in R. toruloides and reconstructed the genome-scale metabolic network of R. toruloides.
Murilo L Bello et al.
PloS one, 10(3), e0121110-e0121110 (2015-03-25)
Layered drug delivery carriers are current targets of nanotechnology studies since they are able to accommodate pharmacologically active substances and are effective at modulating drug release. Sodium montmorillonite (Na-MMT) is a clay that has suitable properties for developing new pharmaceutical
Patricia L Baker et al.
Applied and environmental microbiology, 85(19) (2019-08-04)
The heliobacteria are members of the bacterial order Clostridiales and form the only group of phototrophs in the phylum Firmicutes Several physiological and metabolic characteristics make them an interesting subject of investigation, including their minimalist photosynthetic system, nitrogen fixation abilities
Daisuke Koma et al.
Bioscience, biotechnology, and biochemistry, 78(2), 350-357 (2014-07-19)
The production of chemical compounds from renewable resources is an important issue in building a sustainable society. In this study, Escherichia coli was metabolically engineered by introducing T7lac promoter-controlled aroF(fbr), pabA, pabB, and pabC genes into the chromosome to overproduce
Lei Zhou et al.
Water research, 47(1), 153-162 (2012-10-23)
Dissolved organic matter (DOM) is an important photosensitizer for the phototransformation of organic contaminants in sunlit natural waters. This article focuses on the photolysis kinetics and mechanism of sunscreen agent p-aminobenzoic acid (PABA) in the presence of four kinds of
P G Lankisch et al.
Gastroenterology, 90(2), 350-354 (1986-02-01)
Serum fluorescein and p-aminobenzoic acid were measured during a urine pancreolauryl and an N-benzoyl-l-tyrosyl-p-aminobenzoic acid (NBT-PABA) test in 22 healthy controls, 17 patients with gastrointestinal nonpancreatic diseases (normal secretin-pancreozymin test), and 31 patients with abnormal exocrine pancreatic function due to
Yudi Rusman et al.
Journal of natural products, 76(1), 91-96 (2013-01-16)
During a survey of actinobacteria known to suppress the growth of Streptomyces scabies (the causative agent of potato scab disease) in vivo, six new rhamnosylated alkaloids, the solphenazines A-F (1-6), were isolated from a biological control strain of Streptomyces (DL-93).
E S Lianidou et al.
Clinical chemistry, 42(10), 1659-1665 (1996-10-01)
A novel, sensitive, and selective method has been developed for determination of p-aminobenzoic (PABA) and p-aminosalicylic (PAS) acids in the N-benzoyl-L-tyrosyl-PABA/ PAS test. PAS is measured as a ternary complex with terbium and EDTA (lambda(ex) = 324 nm, lambda(em) =
Nadzeya Kouzel et al.
Journal of bacteriology, 197(14), 2422-2431 (2015-05-13)
Extracellular DNA is an important structural component of many bacterial biofilms. It is unknown, however, to which extent external DNA is used to transfer genes by means of transformation. Here, we quantified the acquisition of multidrug resistance and visualized its
Robert B Campenot et al.
Nature protocols, 4(12), 1869-1887 (2009-12-17)
The compartmented culture, in which primary neurons plated in a proximal compartment send their axons under silicone grease barriers and into left and right distal compartments, has enhanced the experimental capabilities of neuronal cultures. Treatments can be applied separately to
Kirk E Hevener et al.
Journal of medicinal chemistry, 53(1), 166-177 (2009-11-11)
Dihydropteroate synthase (DHPS) is a key enzyme in bacterial folate synthesis and the target of the sulfonamide class of antibacterials. Resistance and toxicities associated with sulfonamides have led to a decrease in their clinical use. Compounds that bind to the
Joachim Michael Matz et al.
Cell reports, 26(2), 356-363 (2019-01-10)
Folate metabolism is essential for DNA synthesis and a validated drug target in fast-growing cell populations, including tumors and malaria parasites. Genome data suggest that Plasmodium has retained its capacity to generate folates de novo. However, the metabolic plasticity of
D Laufer et al.
Gastroenterology, 101(1), 207-213 (1991-07-01)
The bentiromide test was evaluated using plasma p-aminobenzoic acid as an indirect test of pancreatic insufficiency in young children between 2 months and 4 years of age. To determine the optimal test method, the following were examined: (a) the best
A Szewczuk et al.
Clinica chimica acta; international journal of clinical chemistry, 84(1-2), 27-31 (1978-03-01)
A simple colorimetric method for the assay of cobalt-activated acylase activity in human serum using new and less toxic N-chloroacetyl-gamma-L-glutamyl-p-aminobenzoic acid as substrate has been described. The values obtained with this method are almost the same as with the previously
Magdalena Wysocka et al.
Protein and peptide letters, 19(12), 1237-1244 (2012-06-08)
In this work the efficient and simple method of improvement specificity and solubility of low molecular weight proteinase substrates is described. The series of fluorescent substrates of selected proteolytic enzymes (neutrophil elastase, cathepsin G and proteinase 3 along with human
P R Durie et al.
The Journal of pediatrics, 121(3), 413-416 (1992-09-01)
We assessed the diagnostic capability of the bentiromide test using a high-pressure liquid-chromatography method to analyze p-aminobenzoic acid and its metabolites in plasma as an indirect measure of exocrine pancreatic function. Mean total amine concentration in pancreatic-insufficient subjects was significantly
Reza Forghani et al.
Radiology, 263(2), 451-460 (2012-03-23)
To evaluate myeloperoxidase (MPO) as a newer therapeutic target and bis-5-hydroxytryptamide-diethylenetriaminepentaacetate-gadolinium (Gd) (MPO-Gd) as an imaging biomarker for demyelinating diseases such as multiple sclerosis (MS) by using experimental autoimmune encephalomyelitis (EAE), a murine model of MS. Animal experiments were approved
Loyola D'Silva et al.
Magnetic resonance in chemistry : MRC, 50(6), 443-448 (2012-05-04)
Longitudinal multispin order (LOMO) corresponds to a nonequilibrium population distribution in spin systems that exhibit scalar (J), dipolar, or quadrupolar coupling. We investigated the relaxation of longitudinal two-spin order (2-LOMO) in systems that had either weakly or strongly J-coupled spins.
J C Aristizabal et al.
European journal of clinical nutrition, 69(7), 831-836 (2014-10-09)
Fat-free mass (FFM) is the major predictor of resting metabolic rate (RMR). As protein supplementation during resistance training may augment gains in FFM, we investigated the effects of resistance training combined with protein supplementation on RMR and whether RMR responses
Jens O Krömer et al.
Journal of biotechnology, 163(2), 184-193 (2012-05-15)
Aromatics are amongst the most important bulk feedstocks for the chemical industry, however, no viable bioprocess exists today and production is still dependent on petro-chemistry. In this article the production of aromatic precursors such as p-hydroxybenzoic acid (PHBA) and p-amino
Bhupinder Virk et al.
BMC biology, 10, 67-67 (2012-08-02)
Gut microbes influence animal health and thus, are potential targets for interventions that slow aging. Live E. coli provides the nematode worm Caenorhabditis elegans with vital micronutrients, such as folates that cannot be synthesized by animals. However, the microbe also
Peter J McNamara et al.
Antimicrobial agents and chemotherapy, 53(5), 1898-1906 (2009-02-19)
Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have shown that tampon additives can influence staphylococcal TSST-1 production. We report here on
Rupesh K Mishra et al.
Analytica chimica acta, 889, 106-112 (2015-09-08)
Contamination of food by mycotoxin occurs in minute/trace quantities. Nearly 92.5% of the cocoa samples present Ochratoxin A (OTA) levels at trace quantity. Hence, there is a necessity for a highly sensitive and selective device that can detect and quantify
Electropolymerized 4-aminobenzoic acid based voltammetric sensor for the simultaneous determination of food azo dyes
G Ziyatdinova
Polymers, 14, 5429-5429 (2022)
Felipe Conzuelo et al.
Biosensors & bioelectronics, 36(1), 81-88 (2012-04-28)
The preparation and performance of a disposable amperometric immunosensor, based on the use of a selective capture antibody and screen-printed carbon electrodes (SPCEs), for the specific detection and quantification of sulfonamide residues in milk is reported. The antibody was covalently
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