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关键词:'C0625'
显示 1-30 共 365 条结果 关于 "C0625" 范围 论文
Sabrina Okombi et al.
Bioorganic & medicinal chemistry letters, 16(8), 2252-2255 (2006-01-31)
Melanin play a major role in human skin protection and their biosynthesis is vital. Due to their color, they contribute to the skin pigmentation. Tyrosinase is a key enzyme involved in the first stage of melanin synthesis, catalyzing the transformation
Jianming Ren et al.
International journal of biological macromolecules, 53, 77-81 (2012-11-21)
In this work, two kinds of phenolic antioxidants-functionalized quaternized chitosan were synthesized in order to develop aqueous soluble antioxidant-polymer conjugates. Quaternized chitosan conjugated with gallic acid or caffeic acid was carried out and the antioxidant properties of the products (namely
Dejan Stojković et al.
Journal of the science of food and agriculture, 93(13), 3205-3208 (2013-04-05)
Three pure compounds that naturally occur in plants were of particular interest to our study regarding the possibility of using them as food preservatives: p-coumaric acid (found in peanuts, tomatoes, carrots, garlic, wine, vinegar, etc.), caffeic acid (found in argan
Luisaldo Sandate-Flores et al.
Plants (Basel, Switzerland), 9(11) (2020-12-04)
Mexico has a great diversity of cacti, however, many of their fruits have not been studied in greater depth. Several bioactive compounds available in cacti juices extract have demonstrated nutraceutical properties. Two cactus species are interesting for their biologically active
Paolo Benincasa et al.
Journal of the science of food and agriculture, 95(9), 1795-1803 (2014-08-19)
The use of sprouts and young plantlets in human nutrition is increasing because they often contain phytochemicals and other high value nutrients. This is also the case for wheat, although there is no literature for hulled wheat species. Thus we
Antonio de Jesus Cenobio-Galindo et al.
Food science and biotechnology, 28(5), 1553-1561 (2019-11-07)
The use of unconventional sources is very relevant in the food area. In the present study the development of active films with the addition of bioextract (BE) or microencapsulated bioextract (MBE) from xoconostle (Opuntia oligacantha) on chayotextle starch was investigated.
Liangmian Chen et al.
Journal of pharmaceutical and biomedical analysis, 95, 93-101 (2014-03-25)
A novel three-channel isocratic elution high performance liquid chromatography with electrochemical detection (3LC-ECD) system was developed for the simultaneous determination of various bioactive redox components in Shuang-Huang-Lian (SHL) preparations. This 3LC-ECD system consists of three isocratic elution flow ways, two
Marienca Femenía-Ríos et al.
Bioorganic & medicinal chemistry letters, 16(22), 5836-5839 (2006-09-05)
A novel metabolite (-)-1 was isolated as its peracetylated derivative, (-)-2-(3',4'-diacetoxyphenyl)-3,4-diacetoxytetrahydrofuran (2), from a strain of the phytopathogenic fungus Colletotrichum gloeosporioides CECT 20122. The synthesis of (-)-1 was carried out by ring-closing metathesis of diene 6 and stereoselective dihydroxylation of
Muhammed Alzweiri et al.
Journal of enzyme inhibition and medicinal chemistry, 30(3), 420-429 (2014-07-30)
An HPLC-size exclusion method was developed as an assay method to evaluate the binding of tested compounds with carbonic anhydrase III (CAIII) enzyme. Inhibition of CAIII by a group of benzoic acid analogues was characterized by vacancy (negative) peak intensity
Bilal H Abbasi et al.
Applied biochemistry and biotechnology, 168(7), 2057-2066 (2012-10-19)
Gibberellic acid (GA(3)) is reported to have diverse effects on hairy root cultures of many plant species; therefore, the effects of GA(3) on the growth, secondary metabolite production (caffeic acid derivatives and lignin), phenylalanine ammonia lyase (PAL) activity, and free
Parisa Abbasi-Parizad et al.
Antioxidants (Basel, Switzerland), 9(2) (2020-02-27)
Two tomato pomace (TP) were studied as feedstocks to obtain extracts that are rich in polyphenols. TPs prompt degradation impairs biomass safety, thus naturally present microflora were tested to perform conservation, and own lactic bacteria became predominant after 60 days
Amira S El Senousy et al.
Phytochemistry, 108, 67-76 (2014-10-11)
The metabolomic differences in phenolics from leaves derived from 3 artichoke cultivars (Cynara scolymus): American Green Globe, French Hyrious and Egyptian Baladi, collected at different developmental stages, were assessed using UHPLC-MS coupled to chemometrics. Ontogenic changes were considered as leaves
Morshed A Chowdhury et al.
Bioorganic & medicinal chemistry letters, 19(24), 6855-6861 (2009-11-04)
A novel class of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore attached to its C-4 or C-5 position was designed for evaluation as anti-inflammatory (AI) agents. Replacement of the 2,4-difluorophenyl ring in diflunisal by the N-difluoromethyl-1,2-dihydropyrid-2-one moiety provided
Kaisu R Riihinen et al.
Fitoterapia, 97, 78-86 (2014-06-01)
The antimicrobial activity of lingonberry (Vaccinium vitis-idaea L.) was evaluated against two oral pathogens, Streptococcus mutans and Fusobacterium nucleatum. Long-bed gel permeation chromatography (GPC; Sephadex LH-20) yielded purified flavonoids, with the most efficient minimum inhibitory concentrations (MICs) against planktonic cells
María-Ángeles Del-Castillo-Alonso et al.
Journal of the science of food and agriculture, 95(2), 409-416 (2014-05-14)
Ultraviolet (UV) radiation induces adaptive responses that can be used for plant production improvement. The aim of this study was to assess the effect of solar UV exclusion on the physiology and phenolic compounds of leaves and berry skins of
Pamela Somers et al.
The Journal of heart valve disease, 24(1), 92-100 (2015-07-18)
Currently, no effective crosslinking reagents are available to treat xenogenic decellularized heart valve matrices. The study aim was to evaluate the crosslinking effect of quercetin, catechin, caffeic acid and tannic acid on porcine aortic valve matrices. Cytotoxicity of the different
Sung-Yong Yang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 55, 92-99 (2013-01-12)
Perilla frutescens leaves are often used in East Asian gourmet food. In this study, we investigated the hepatoprotective effects of caffeic acid (CA), rosmarinic acid (RA), and their combination. P. frutescens contains 1.32μg CA/mg dry material (DM) and 26.84μg RA/mg
Fuad Al-Rimawi et al.
Journal of AOAC International, 98(5), 1335-1339 (2015-11-04)
A simple, precise, accurate, and selective method was developed and validated for determination of eight phenolic compounds (gallic acid, p-hydroxybenzoic acid, vanilic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid, and sinapic acid) in date palms. Separation was achieved
See-Hyoung Park et al.
Bioorganic & medicinal chemistry, 15(11), 3938-3950 (2007-04-10)
The antagonists for the SH2 domain are regarded as novel therapeutic candidates for cancer, autoimmune disease, and chronic inflammatory disease. Previously, we identified rosmarinic acid (alpha-o-caffeoyl-3,4-dihydroxyphenyl-lactic acid; RosA) from Prunella vulgaris as an antagonist for the p56lck SH2 domain by
Flávia Santi Stefanello et al.
Food chemistry, 239, 385-401 (2017-09-07)
Brewer's spent grain (BSG) could be tested as an alternative source of polyphenols in animal nutrition. Proper extraction and analytical methods are critical for quantification. Thus, extraction for BSG, corn silage, and brans of rice, corn, and wheat were studied
Debora Giordano et al.
Food chemistry, 233, 483-491 (2017-05-23)
In this study, the chemical composition of pigmented wheats (yellow, purple and blue types), and the distribution of the bioactive compounds in their roller-milled and pearled fractions, were compared with conventional wheats (red and white types). Roller-milling promoted the recovery
Tânia B Ribeiro et al.
Food research international (Ottawa, Ont.), 142, 110032-110032 (2021-03-29)
Pulp-enriched powder (POPP) was obtained from olive pomace solid fraction, a derived from the new value chain established for olive by-products. As a multifunctional powder, POPP retains several bioactive compounds (fatty acids, dietary fibre and phenolics) under potential synergic interaction
E Pontiki et al.
Bioorganic & medicinal chemistry, 15(17), 5819-5827 (2007-07-03)
Lipoxygenase catalyzes the first two steps of the transformation of arachidonic acid into leukotrienes which are implicated in host defense reactions. It is well known that many acids possess potent anti-inflammatory activity. Taking into account that compounds bearing a thienyl
Miriam Martínez-Huélamo et al.
Food chemistry, 173, 864-872 (2014-12-04)
Tomato sauce is the most commonly consumed processed tomato product worldwide, but very little is known about how the manufacturing process may affect the phenolic composition and bioavailability after consumption. In a prospective randomised, cross-over intervention study, we analysed the
Ericsson David Coy et al.
Bioorganic & medicinal chemistry letters, 19(24), 6922-6925 (2009-11-03)
The anti-inflammatory potential of 26 neolignans (14 of the bicyclooctane-type and 12 of the benzofuran-type), isolated from three Lauraceae species (Pleurothyrium cinereum, Ocotea macrophylla and Nectandra amazonum), was evaluated in vitro through inhibition of COX-1, COX-2, 5-LOX and agonist-induced aggregation
Giuseppe M Lombardo et al.
Dalton transactions (Cambridge, England : 2003), 41(47), 14337-14344 (2012-10-10)
The vast literature concerning caffeic acid and its derivatives lacks any reference to the solid state structures of its inorganic salts as these crystals are quite difficult grow. Most of the already published works deal with computational studies of these
Alexandra Gaspar et al.
European journal of medicinal chemistry, 44(5), 2092-2099 (2008-12-09)
An interdisciplinary research project was developed combining the synthesis of a series of hydroxycinnamic acid derivatives and the evaluation of their physicochemical parameters (namely redox potentials and partition coefficients), along with the corresponding antioxidant activity. A structure-property-activity relationship (SPAR) approach
Midori Soda et al.
European journal of medicinal chemistry, 48, 321-329 (2012-01-13)
Inhibitors of a human aldo-keto reductase, AKR1B10, are regarded as promising therapeutics for the treatment of cancer, but those with both high potency and selectivity compared to the structurally similar aldose reductase (AKR1B1) have not been reported. In this study
Ebubekir Izol et al.
Chemistry & biodiversity, 18(1), e2000560-e2000560 (2020-11-15)
Allium species are widely consumed as food all over the world. The phenolic profile of ethanol extracts of aerial parts and roots of 12 Allium species, collected from five different Eastern Anatolia regions, were studied using LC-MS/MS. In vitro antioxidant
Hisashi Matsuda et al.
Bioorganic & medicinal chemistry letters, 15(7), 1949-1953 (2005-03-23)
1'S-1'-Acetoxychavicol acetate from the rhizomes of Alpinia galanga inhibited nitric oxide (NO) production in lipopolysaccharide-activated mouse peritoneal macrophages with an IC(50) value of 2.3 microM. To clarify the structure-activity relationship of 1'S-1'-acetoxychavicol acetate, various natural and synthetic phenylpropanoids and synthetic
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