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Koji Uwai et al.
Bioorganic & medicinal chemistry, 16(16), 7795-7803 (2008-08-01)
Caffeic acid esters, one of the components of propolis, are known to show a variety of biological effects such as anti-tumor, anti-oxidant, and anti-inflammatory activities. Although, the anti-inflammatory activities of caffeic acid esters have been studied by analyzing their structure
Pamela Somers et al.
The Journal of heart valve disease, 24(1), 92-100 (2015-07-18)
Currently, no effective crosslinking reagents are available to treat xenogenic decellularized heart valve matrices. The study aim was to evaluate the crosslinking effect of quercetin, catechin, caffeic acid and tannic acid on porcine aortic valve matrices. Cytotoxicity of the different
María-Ángeles Del-Castillo-Alonso et al.
Journal of the science of food and agriculture, 95(2), 409-416 (2014-05-14)
Ultraviolet (UV) radiation induces adaptive responses that can be used for plant production improvement. The aim of this study was to assess the effect of solar UV exclusion on the physiology and phenolic compounds of leaves and berry skins of
Kaisu R Riihinen et al.
Fitoterapia, 97, 78-86 (2014-06-01)
The antimicrobial activity of lingonberry (Vaccinium vitis-idaea L.) was evaluated against two oral pathogens, Streptococcus mutans and Fusobacterium nucleatum. Long-bed gel permeation chromatography (GPC; Sephadex LH-20) yielded purified flavonoids, with the most efficient minimum inhibitory concentrations (MICs) against planktonic cells
Sung-Yong Yang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 55, 92-99 (2013-01-12)
Perilla frutescens leaves are often used in East Asian gourmet food. In this study, we investigated the hepatoprotective effects of caffeic acid (CA), rosmarinic acid (RA), and their combination. P. frutescens contains 1.32μg CA/mg dry material (DM) and 26.84μg RA/mg
Ekhtear Hossain et al.
Molecular and cellular biochemistry, 400(1-2), 29-40 (2014-10-29)
There is a growing body of evidence supporting an intimate association of immune activation with the pathogenesis of cardiovascular diseases, including atherosclerosis. Uptake of oxidized low-density lipoprotein (oxLDL) through scavenging receptors promotes the formation of mature lipid-laden macrophages, which subsequently
Morshed A Chowdhury et al.
Bioorganic & medicinal chemistry letters, 19(24), 6855-6861 (2009-11-04)
A novel class of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore attached to its C-4 or C-5 position was designed for evaluation as anti-inflammatory (AI) agents. Replacement of the 2,4-difluorophenyl ring in diflunisal by the N-difluoromethyl-1,2-dihydropyrid-2-one moiety provided
Claudia-Crina Toma et al.
Molecules (Basel, Switzerland), 20(6), 9560-9574 (2015-05-29)
This study was performed to evaluate the phenolic profile, antioxidant and diuretic effects of black cumin and lady-in-a-mist seeds. In the phenolic profile, differences between the two species are significant. Qualitative and quantitative analyses of the phenolic compounds were performed
Leina Hou et al.
Heliyon, 10(12), e32623-e32623 (2024-07-08)
Diabetic neuropathy (DN) represents a common and debilitating complication of diabetes, affecting a significant proportion of patients. Despite available treatments focusing on symptom management, there remains an unmet need for therapies that address the underlying pathophysiology. In pursuit of novel
Abdullah Al Maruf et al.
Chemico-biological interactions, 234, 96-104 (2014-12-03)
Glyoxal (GO) and methylglyoxal (MGO) cause protein and nucleic acid carbonylation and oxidative stress by forming reactive oxygen and carbonyl species which have been associated with toxic effects that may contribute to cardiovascular disease, complications associated with diabetes mellitus, Alzheimer's
Giuliano E Pereira et al.
Frontiers in plant science, 11, 707-707 (2020-07-01)
Girdling is a traditional horticultural practice applied at fruit set or other phenological stages, and is used mostly as a vine management. In grapevines, it is used primarily for table grapes to improve berry weight, sugar content, color, and to
Dongping Liu et al.
Bioorganic & medicinal chemistry letters, 21(22), 6833-6837 (2011-10-04)
Src homology-2 domain-containing protein tyrosine phosphatase (Shp2), a novel proto-oncogenic protein, is an important target in cancer therapy research. Approximately 2000 plant extracts were screened to find its natural specific inhibitors, with the ethyl acetate (EtOAc) active extract of the
Miloš Ilić et al.
Bioorganic & medicinal chemistry letters, 21(16), 4705-4709 (2011-07-16)
Vascular oxidative stress, endothelial injury, and thrombosis are intertwined processes that display a synergistic pathological effect in many cardiovascular diseases. Antithrombotic therapy with anticoagulant and/or antiplatelet agents, combined with interventions against vascular oxidative stress and/or inflammation, both boosting endothelial antithrombotic
Wendy R Russell et al.
Bioorganic & medicinal chemistry, 16(8), 4589-4593 (2008-03-04)
Elevated levels of phospholipases, prostaglandin synthases and lipoxygenases in colonic cells at various stages of malignancy indicate a strong link between dietary lipids and colon cancer. Lipoxygenase-catalysed arachidonic acid metabolism plays a key role in colorectal carcinogenesis and has the
Cleverson Antonio Ferreira Martins et al.
Biomedical chromatography : BMC, 28(7), 986-993 (2014-01-10)
Malva sylvestris is a species used worldwide as an alternative to anti-inflammatory therapies; however, its mechanism of action remains unknown. In this paper, the anti-inflammatory effects of M. sylvestris alcoholic extracts were evaluated by measuring the pro-inflammatory mediators PGE₂ and
Hnin Thanda Aung et al.
Bioorganic & medicinal chemistry, 19(7), 2392-2396 (2011-03-11)
In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic acid (2) and 3-(3,4-dihydroxyphenyl)lactic acid (3). In this study, we investigated the
B Y Hsu et al.
Journal of pharmaceutical and biomedical analysis, 132, 109-116 (2016-10-05)
A high performance liquid chromatography-diode array detection-tandem mass spectrometry method (HPLC-DAD-MS/MS) was developed for simultaneous determination of phenolic acids and flavonoids in djulis (Chenopodium formosanum Koidz.), a traditional Chinese herb reported to possess vital biological activities. A high yield of
Luisaldo Sandate-Flores et al.
Plants (Basel, Switzerland), 9(11) (2020-12-04)
Mexico has a great diversity of cacti, however, many of their fruits have not been studied in greater depth. Several bioactive compounds available in cacti juices extract have demonstrated nutraceutical properties. Two cactus species are interesting for their biologically active
Andrei Mocan et al.
International journal of molecular sciences, 16(9), 21109-21127 (2015-09-26)
Aerial parts of Veronica species are used in Romanian traditional medicine for the treatment of various conditions like kidney diseases, cough, and catarrh, and are known for their wound-healing properties. In the present study, the phenolic and sterolic content and
C Haris Saslis-Lagoudakis et al.
Scientific reports, 5, 11942-11942 (2015-07-15)
The global herbal products market has grown in recent years, making regulation of these products paramount for public healthcare. For instance, the common horsetail (Equisetum arvense L.) is used in numerous herbal products, but it can be adulterated with closely
Fuad Al-Rimawi et al.
Journal of AOAC International, 98(5), 1335-1339 (2015-11-04)
A simple, precise, accurate, and selective method was developed and validated for determination of eight phenolic compounds (gallic acid, p-hydroxybenzoic acid, vanilic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid, and sinapic acid) in date palms. Separation was achieved
Dejan Stojković et al.
Journal of the science of food and agriculture, 93(13), 3205-3208 (2013-04-05)
Three pure compounds that naturally occur in plants were of particular interest to our study regarding the possibility of using them as food preservatives: p-coumaric acid (found in peanuts, tomatoes, carrots, garlic, wine, vinegar, etc.), caffeic acid (found in argan
Sabrina Okombi et al.
Bioorganic & medicinal chemistry letters, 16(8), 2252-2255 (2006-01-31)
Melanin play a major role in human skin protection and their biosynthesis is vital. Due to their color, they contribute to the skin pigmentation. Tyrosinase is a key enzyme involved in the first stage of melanin synthesis, catalyzing the transformation
Jianming Ren et al.
International journal of biological macromolecules, 53, 77-81 (2012-11-21)
In this work, two kinds of phenolic antioxidants-functionalized quaternized chitosan were synthesized in order to develop aqueous soluble antioxidant-polymer conjugates. Quaternized chitosan conjugated with gallic acid or caffeic acid was carried out and the antioxidant properties of the products (namely
Paolo Benincasa et al.
Journal of the science of food and agriculture, 95(9), 1795-1803 (2014-08-19)
The use of sprouts and young plantlets in human nutrition is increasing because they often contain phytochemicals and other high value nutrients. This is also the case for wheat, although there is no literature for hulled wheat species. Thus we
Xiao-Hong Ma et al.
Chemosphere, 246, 125849-125849 (2020-02-26)
The sodium pyrophosphate (SP)-enhanced Fenton reaction has been proven to have promising potential in remediation of polychlorinated biphenyls in soils by keeping iron ions soluble at high pH and minimizing the useless decomposition of H2O2. However, little information can be
Meltem Türkyılmaz et al.
Journal of the science of food and agriculture, 94(12), 2488-2496 (2014-01-22)
This study was conducted to determine the differences in some analytical properties of four apricot cultivars and to determine the changes in these analytical properties during sulfuring and sun-drying. There were significant differences in the contents of polyphenols, carotenoids and
Flávia Santi Stefanello et al.
Food chemistry, 239, 385-401 (2017-09-07)
Brewer's spent grain (BSG) could be tested as an alternative source of polyphenols in animal nutrition. Proper extraction and analytical methods are critical for quantification. Thus, extraction for BSG, corn silage, and brans of rice, corn, and wheat were studied
Fátima de Campos Buzzi et al.
European journal of medicinal chemistry, 44(11), 4596-4602 (2009-07-25)
Ten ester derivatives from caffeic acid were synthesized, and their antinociceptive properties are evaluated in mice. The most active compound, dodecyl ester derivative, exhibited potent and dose-related activity against the writhing test, with a calculated ID(50) value of 15.1 (11.9-19.1)micromol/kg
Eldiza Puji Rahmi et al.
Pharmacognosy magazine, 13(Suppl 3), S578-S586 (2017-11-17)
To evaluate the inhibitory effects of three The leaves and roots of DCM extract of MPL roots showed the highest inhibition of LPS-stimulated cytokine secretion with IC The results suggested that DCM extracts of MPL and MPP roots are potential
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