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关键词:'C1879'
显示 1-30 共 184 条结果 关于 "C1879" 范围 论文
Xian-Fei Zeng et al.
Research in microbiology, 165(8), 630-638 (2014-10-07)
LicC has been identified as a virulence factor of Streptococcus pneumoniae. However, its role in virulence is still not fully understood because deletion of licC is lethal for the bacterium. In this study, a mutant with 78-bp truncation at the
Marina Hodolič et al.
Clinical nuclear medicine, 38(9), 739-740 (2013-07-03)
A 59-year-old man presented with frequent urination. Six months ago, his prostate-specific antigen (PSA) was 1.56 ng/mL; currently it is 3.5 ng/mL (PSA doubling time = 6 months; PSA velocity = 0.19 ng/mL/mo). Biopsy revealed aggressive prostate cancer (Gleason score
Jing-Li Gan et al.
Psychiatry research, 223(1), 23-27 (2014-05-17)
Early onset schizophrenia (EOS) is often associated with poorer outcomes, including lack of school education, higher risk of mental disability and resistance to treatment. But the knowledge of the neurobiological mechanism of EOS is limited. Here, using proton magnetic resonance
Amy Eccles et al.
Clinical nuclear medicine, 38(9), 755-757 (2013-07-17)
A 63-year-old man underwent a (18)F-fluorocholine ((18)F-FCH) PET/CT for staging assessment of a high-risk locally advanced prostate cancer with an equivocal node on conventional workup (Gleason 4 + 5, PSA 11.1; T3b, N(0/1), M(0) on standard staging investigations). (18)F-FCH-avid disease
Tatiana V Vygodina et al.
Biochimica et biophysica acta, 1837(7), 1188-1195 (2014-03-13)
Cytochrome c oxidase from bovine heart binds Ca(2+) reversibly at a specific Cation Binding Site located near the outer face of the mitochondrial membrane. Ca(2+) shifts the absorption spectrum of heme a, which allowed earlier the determination of the kinetic
A Collin de l'Hortet et al.
Endocrinology, 155(7), 2545-2554 (2014-04-09)
GH pathway has been shown to play a major role in liver regeneration through the control of epidermal growth factor receptor (EGFR) activation. This pathway is down-regulated in nonalcoholic fatty liver disease. Because regeneration is known to be impaired in
Hussain Mohamad Awwad et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 957, 41-45 (2014-03-29)
We aimed at developing a method for the measurement of choline and its metabolites in whole blood (WB). After an extraction step, quantification of choline, betaine, and dimethylglycine (DMG) was performed using ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS).
Jian-Zhuang Tan et al.
Journal of the science of food and agriculture, 95(1), 126-135 (2014-04-15)
The effects of dietary l-arginine (Arg) on immunosuppression following infectious bursal disease virus (IBDV) inoculation in broiler chickens were evaluated. The design of this study was a 5 × 2 factorial arrangement (n = 5) with five Arg concentrations (starter:
Ilias Patmanidis et al.
Journal of molecular graphics & modelling, 41, 68-71 (2013-03-19)
Folding simulations of a choline-binding peptide derived from the Streptococcus pneumoniae LytA protein converged to a model of the peptide's folded state structure which is in outstanding agreement with the experimentally-determined structures, reaching values for the root mean squared deviation
Giles S Kendall et al.
Radiology, 271(1), 230-238 (2014-01-31)
To determine (a) whether diffuse white matter injury of prematurity is associated with an increased choline (Cho)-to-creatine (Cr) ratio and a reduced N-acetylaspartate (NAA)-to-Cho ratio and whether these measures can be used as biomarkers of outcome and (b) if changes
Baokun Tang et al.
Journal of chromatographic science, 53(5), 836-840 (2014-09-18)
Three flavones (quercetin, myricetin and amentoflavone) were extracted from Chamaecyparis obtusa leaves using deep eutectic solvents (DESs) as additives to conventional extractions solvents. Sixteen DESs were synthesized from different salts and hydrogen bond donors. In addition, C. obtusa was extracted
Marcelo Mamede et al.
Clinical nuclear medicine, 38(9), e342-e345 (2013-06-26)
This study aims to evaluate the role of (11)C-choline PET/CT in patients with biochemical relapse after radical prostatectomy (RP) showing prostate-specific antigen (PSA) values lower than 0.5 ng/mL. We performed (11)C-choline PET/CT in 71 consecutive patients previously treated with RP
Marcin Wysokowski et al.
RSC advances, 13(32), 21971-21981 (2023-07-24)
Tissue engineering is a burgeoning field focused on repairing damaged tissues through the combination of bodily cells with highly porous scaffold biomaterials, which serve as templates for tissue regeneration, thus facilitating the growth of new tissue. Carbon materials, constituting an
Paula Dominguez-Salas et al.
The American journal of clinical nutrition, 97(6), 1217-1227 (2013-04-12)
Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have been observed in offspring whose mothers were
Xin Jin et al.
Acta pharmacologica Sinica, 36(12), 1416-1425 (2015-11-17)
To determine whether administration of choline could attenuate brain injury in a rat model of ischemic stroke and the underlying mechanisms. A rat model of ischemic stroke was established through permanent middle cerebral artery occlusion (pMCAO). After the surgery, the
Mads H Poulsen et al.
BJU international, 114(6), 818-823 (2013-12-10)
To compare the diagnostic accuracy of the following imaging techniques in the detection of spine metastases, using magnetic resonance imaging (MRI) as a reference: whole-body bone scintigraphy (WBS) with technetium-99m-MDP, [18F]-sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) and
Alexandra Deviers et al.
International journal of radiation oncology, biology, physics, 90(2), 385-393 (2014-08-12)
Because lactate accumulation is considered a surrogate for hypoxia and tumor radiation resistance, we studied the spatial distribution of the lactate-to-N-acetyl-aspartate ratio (LNR) before radiation therapy (RT) with 3D proton magnetic resonance spectroscopic imaging (3D-(1)H-MRSI) and assessed its impact on
Dale A Fortin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(50), 16698-16712 (2014-12-17)
Stoichiometric labeling of endogenous synaptic proteins for high-contrast live-cell imaging in brain tissue remains challenging. Here, we describe a conditional mouse genetic strategy termed endogenous labeling via exon duplication (ENABLED), which can be used to fluorescently label endogenous proteins with
Andrew J Ocque et al.
Journal of pharmaceutical and biomedical analysis, 109, 128-135 (2015-03-15)
A simple, sensitive, and precise ultra-high performance liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine. Sample preparation involved protein precipitation with methanol containing internal
Vincent A van der Mark et al.
Biochimica et biophysica acta, 1842(12 Pt A), 2378-2386 (2014-09-23)
Deficiency of the phospholipid flippase ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ATP8B1) causes progressive familial intrahepatic cholestasis type 1 (PFIC1) and benign recurrent intrahepatic cholestasis type 1 (BRIC1). Apart from cholestasis, many patients also suffer from diarrhea
Artor Niccoli-Asabella et al.
Recenti progressi in medicina, 104(2), 73-75 (2013-03-29)
In a patient with cerebral gliomatosis type II MRI revealed a large area of altered signal in the temporal region, parietal and occipital lobes associated with a single nodule with perilesional contrast enhancement, which showed increased uptake on PET/CT with
Vignesh Thiagarajan et al.
Journal of colloid and interface science, 462, 334-340 (2015-10-18)
Choline, a type of Vitamin B, is an important nutrient in the human body and is involved in key metabolic pathways. Abnormal levels of choline leads to diseased conditions. The levels of choline and its associated compounds are found to
Tom Vander Hoogerstraete et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(33), 11757-11766 (2015-07-17)
In a conventional solvent extraction system, metal ions are distributed between two immiscible phases, typically an aqueous and an organic phase. In this paper, the proof-of-principle is given for the distribution of metal ions between three immiscible phases, two ionic
L Van den Bergh et al.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 189(9), 789-795 (2013-06-26)
The aim of this work was to determine whether 11C-choline positron emission tomography (PET)-computed tomography (CT) makes a positive contribution to multiparametric magnetic resonance imaging (MRI) for localisation of intraprostatic tumour nodules. A total of 73 patients with biopsy-proven intermediate-
N Andres Parra et al.
International journal of radiation oncology, biology, physics, 90(2), 376-384 (2014-07-30)
Magnetic resonance (MR) imaging and computed tomography (CT) are used almost exclusively in radiation therapy planning of glioblastoma multiforme (GBM), despite their well-recognized limitations. MR spectroscopic imaging (MRSI) can identify biochemical patterns associated with normal brain and tumor, predominantly by
Femke S den Boon et al.
Pflugers Archiv : European journal of physiology, 467(7), 1551-1564 (2014-08-02)
Activation of the endocannabinoid (eCB) system by exogenous cannabinoids (drug abuse) can alter the physiology of the brain circuits involved in higher-order cognitive functions such as the medial prefrontal cortex (mPFC). A proper balance between excitation and inhibition (E/I balance)
Alexandra Petruş et al.
Canadian journal of physiology and pharmacology, 93(9), 811-818 (2015-09-02)
A substantial body of evidence indicates that pharmacological activation of mitochondrial ATP-sensitive potassium channels (mKATP) in the heart is protective in conditions associated with ischemia/reperfusion injury. Several mechanisms have been postulated to be responsible for cardioprotection, including the modulation of
Ling Li et al.
Macromolecular bioscience, 15(7), 912-926 (2015-03-25)
Herein, an effective gene delivery vector phosphorylcholine and macrocyclic polyamine grafted chitosan (PC-g(6)-Cs-g(2)-Cyclen) was developed. Chemical characterization of product PC-g(6)-Cs-g(2)-Cyclen was performed by NMR, FT-IR, gel permeation chromatography (GPC), and X-ray photoelectron spectroscopy (XPS) analysis. PC-g(6)-Cs-g(2)-Cyclen could more efficiently bind
Katherine D Weaver et al.
Biochimica et biophysica acta, 1828(8), 1856-1862 (2013-04-02)
To better understand the relationship between the relative cytotoxicity of diluted ionic liquids and their specific interaction with biological membranes, the thermotropic behavior of model lipid membrane systems formulated in a series of choline based organic salts was investigated. Unilamellar
Kristin Zscharnack et al.
Analytica chimica acta, 854, 145-152 (2014-12-07)
H2O2 is a widely occurring molecule which is also a byproduct of a number of enzymatic reactions. It can therefore be used to quantify the corresponding enzymatic substrates. In this study, the time-resolved fluorescence emission of a previously described complex
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