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Ha-Na Kim et al.
Diabetology & metabolic syndrome, 7, 68-68 (2015-08-20)
Obesity is a risk factor for cardiovascular disease, but metabolic disturbances can also lead to the development of this disease. Therefore, we investigated the associations between obesity subtype, considering both body weight and metabolic disturbances, and carotid atherosclerosis as a
Brian K Nordskog et al.
Inhalation toxicology, 27(3), 157-166 (2015-03-20)
An age-stratified, cross-sectional study was conducted in the US among healthy adult male cigarette smokers, moist snuff consumers, and non-tobacco consumers to evaluate cardiovascular biomarkers of biological effect (BoBE). Physiological assessments included flow-mediated dilation, ankle-brachial index, carotid intima-media thickness and
Mi Hyeong Kim et al.
Clinical transplantation, 29(4), 365-372 (2015-02-04)
The outcome of ABO-incompatible kidney transplantation (ABOi KT) has improved and is now comparable to that of ABO-compatible kidney transplantation (ABOc KT). However, ABOi KT may be associated with a higher risk of postoperative bleeding than ABOc KT. Seventy patients
Naser Aslanabadi et al.
European journal of clinical pharmacology, 71(2), 143-149 (2014-12-06)
Periprocedural myocardial injury (PMI) following percutaneous coronary intervention (PCI) has received great attention due to its significant association with mortality and morbidity. Accordingly, cardioprotection during PCI is one of the important therapeutic concerns. Regarding the potential cardiovascular benefits of pentoxifylline
Koji Harada et al.
Clinical nephrology, 82(2), 107-114 (2014-07-06)
It is important to establish glycemic markers which reflect accurate glycemic status in advanced chronic kidney disease (CKD) patients; however, adequate glycemic markers have not been established. We evaluated the accuracy of glycemic markers in non-dialysis CKD patients. 139 non-dialysis
Ashique Ali Khoso et al.
Pakistan journal of medical sciences, 30(6), 1180-1185 (2015-02-13)
Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery are two alternative methods for coronary revascularization, but it remains controversial as which one is associated with lower risks of worse clinical outcomes for chronic kidney disease (CKD) patients.
Kevin R Bainey et al.
American heart journal, 170(1), 110-116 (2015-06-22)
It is unclear if holding angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) prior to coronary angiography reduces contrast-induced acute kidney injury (AKI). We undertook a randomized trial to investigate the effect of holding ACEI/ARB therapy prior to coronary
Magdalena Madero et al.
Current opinion in nephrology and hypertension, 20(6), 622-630 (2011-09-24)
To discuss the most commonly used creatinine-based glomerular filtration rate (GFR) estimating equations, focus on the modification of diet in renal disease (MDRD) equation and the chronic kidney disease epidemiology collaboration (CKD-EPI) equation, and review studies that have directly compared
James M Kuczmarski et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(5), 482-491 (2014-07-26)
The purpose of this investigation was to determine the effect of 4 wk of voluntary wheel running on cardiac performance in the 5/6 ablation-infarction (AI) rat model of chronic kidney disease (CKD). We hypothesized that voluntary wheel running would be
Lawrence F Eichenfield et al.
Pediatric dermatology, 32(1), 28-35 (2014-11-22)
The objective of this study was to assess the safety and efficacy of the fixed combination calcipotriene 0.005% plus betamethasone dipropionate 0.064% topical suspension in adolescents with extensive scalp psoriasis. In this phase II, open-label, 8-week study, adolescents with psoriasis
Comparison between three systems of classification criteria in juvenile systemic lupus erythematous.
Adriana R Fonseca et al.
Rheumatology (Oxford, England), 54(2), 241-247 (2014-08-16)
The most widely used classification criteria for SLE are those derived and validated in adult patients by the ACR. Alternatives include the Boston weighted (BW) and SLICC criteria. The aim of this study was to compare the performance of BW
Yitschak Biton et al.
Heart failure reviews, 20(5), 535-543 (2015-07-29)
Early intervention with cardiac resynchronization therapy with defibrillator (CRT-D) in mild heart failure (HF) patients with a left bundle branch block (LBBB) ECG pattern was associated with a significant reduction in mortality in the long-term MADIT-CRT trial. Whether patients in
K Hopes et al.
The Analyst, 140(9), 3028-3038 (2015-03-10)
Experiments into the relationship between diet and health have been an area of high interest for a long time. In this study, we investigate the application of multivariate data analysis to differentiate between rat populations fed on two different diets:
Setor K Kunutsor et al.
Atherosclerosis, 238(2), 356-364 (2015-01-03)
The value of measuring levels of gamma glutamyltransferase (GGT) for the prediction of first cardiovascular events is uncertain. We aimed to determine whether adding information on GGT values to conventional cardiovascular risk factors is associated with improvement in prediction of
Chin-Chi Kuo et al.
Environment international, 76, 32-40 (2014-12-17)
There is very limited information on the association between arsenic and serum uric acid levels or gout. The aim of this study was to investigate the association of arsenic with hyperuricemia and gout in US adults. A cross-sectional study was
Chul-Hee Kim et al.
Diabetes research and clinical practice, 106(2), e18-e21 (2014-10-02)
We investigated the association between microalbuminuria and prediabetes in Korean population using data from the KNHANES 2011-2012. Prevalence of microalbuminuria was significantly increased in prediabetes group. However, the odds ratio became insignificant after adjustment for blood pressure, and the prevalence
Jin-Song Shen et al.
Human molecular genetics, 24(11), 3181-3191 (2015-02-24)
Fabry disease is caused by deficient activity of lysosomal enzyme α-galactosidase A. The enzyme deficiency results in intracellular accumulation of glycosphingolipids, leading to a variety of clinical manifestations including hypertrophic cardiomyopathy and renal insufficiency. The mechanism through which glycosphingolipid accumulation
Takafumi Ito et al.
International urology and nephrology, 47(1), 131-135 (2014-10-10)
We have previously reported the results of mizoribine (MZR) treatment for elderly patients with membranous nephropathy (MN). Here, we retrospectively compared these patients with those who had been initially treated with prednisolone (PSL) alone. The subjects were patients with MN
Yuan Du et al.
Clinical hemorheology and microcirculation, 61(1), 1-11 (2014-01-15)
Living-donor renal transplantation is an ideal treatment for patients with end stage renal disease because it affords earlier transplantation and better graft for long term survival. CD14+ monocytes are the predominant inflammatory cells in renal allograft intimal arteritis. The biomechanical
Nao Kawabata et al.
Internal medicine (Tokyo, Japan), 54(3), 311-317 (2015-03-10)
The aim of our study was to investigate clinical and nutritional factors associated with renal involvement in patients with type 2 diabetes. We performed a cross-sectional study of 71 patients with type 2 diabetes who were being educated at our
Antonis Myridakis et al.
Environment international, 83, 1-10 (2015-06-15)
Exposure to endocrine disruptors, used as additives, preservatives, plasticisers and solvents in numerous consumer products, might cause adverse health effects. Humans exposed to these chemicals, metabolise and excrete them mostly via urine. Urinary metabolite concentrations are used as biomarkers of
Maeve P Crowley et al.
Journal of thrombosis and thrombolysis, 39(2), 245-249 (2014-10-02)
The link between myeloma and thrombosis is well established. Monoclonal gammopathy of undetermined significance (MGUS) has also been associated with an increased risk of thrombosis. It was recently demonstrated that patients with myeloma display changes in thromboelastometry that may indicate
H M Dann et al.
Journal of dairy science, 98(6), 4041-4054 (2015-04-22)
Increases in grain prices have led to renewed interest in feeding reduced-starch diets to lactating dairy cows. An experiment was conducted to determine the effects of altering carbohydrate sources and reducing dietary starch on lactational performance, feeding behavior, and ruminal
Britta George et al.
Kidney international, 85(6), 1382-1394 (2014-02-07)
Activation of the slit diaphragm protein nephrin induces actin cytoskeletal remodeling, resulting in lamellipodia formation in podocytes in vitro in a phosphatidylinositol-3 kinase-, focal adhesion kinase-, Cas-, and Crk1/2-dependent fashion. In mice, podocyte-specific deletion of Crk1/2 prevents or attenuates foot
Annalise E Zemlin et al.
Journal of clinical pathology, 68(2), 148-153 (2014-12-03)
Serum free light chain measurements are used to follow-up and manage patients with monoclonal gammopathies, and abnormal ratios are associated with risk of progression in certain diseases. B cell dysfunction is well described in HIV and patients are at risk
Charlotte A Keyzer et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 65(3), 474-483 (2014-12-03)
Vitamin K modulates calcification by activating calcification inhibitors such as matrix Gla protein (MGP). In kidney transplant recipients, vitamin K insufficiency is common, but implications for long-term outcomes are unclear. Single-center observational study with a longitudinal design. 518 stable kidney
Kristen F Bink
Clinical journal of oncology nursing, 19(5), E108-E114 (2015-09-29)
Bisphosphonates, which are also known as osteoclast modifiers, are the standard of care in the treatment of skeletal-related events (SREs) in patients with breast cancer with metastatic bone disease. SREs are frequently a complication of advanced breast cancer, and they
Ibrahim Sehitoglu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 34(1), 53-61 (2015-03-10)
Zoledronic acid (ZA), a bisphosphonate, increases the levels of cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), and reactive oxygen species (ROS) in subjects without cancer. Increased production of ROS, TNF-α, and IL-6 during ischemia and reperfusion
Yang Gyun Kim et al.
PloS one, 10(9), e0137044-e0137044 (2015-09-09)
A proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor (TNF) superfamily. Despite advances in clinical and genetic studies, the details of the pathological roles of APRIL in IgA nephropathy (IgAN) remain to be fully defined. The present
Hahn-Ey Lee et al.
Journal of pediatric urology, 10(6), 1083-1088 (2014-05-27)
Few reports discuss post-pubertal renal complications after pyeloplasty. We analyzed long-term complications, such as decreased renal function (RF) measured by serum creatinine (SCr), hypertension (HTN), or proteinuria (protU) following pediatric pyeloplasty. We retrospectively investigated 257 patients who underwent dismembered pyeloplasty
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