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Looking for a better creatinine.
Jeffrey W Meeusen et al.
Clinical chemistry, 60(8), 1036-1039 (2014-02-28)
Sean M Hays et al.
Environmental health perspectives, 123(4), 293-300 (2015-01-28)
Urinary analyte concentrations are affected both by exposure level and by urinary flow rate (UFR). Systematic variations in UFR with demographic characteristics or body mass index (BMI) could confound assessment of associations between health outcomes and biomarker concentrations. We assessed
Study of Creatinine and its 5-Alkoxy Analogs: Structure and Conformational Studies in the Solid and Solution States by X-Ray Crystallography, NMR, UV and Mass Spectrometry
Arakali AV, et al.
Nucleosides, nucleotides & nucleic acids, 16(12), 2193-2218 (1997)
Jeanette K S Nielsen et al.
International journal of hygiene and environmental health, 218(1), 28-33 (2014-08-16)
Recent studies indicate an association between the use of paracetamol during pregnancy and reproductive disorders in male offspring. Furthermore, N-acetyl-4-aminophenol (NAAP, paracetamol) has been shown to be ubiquitously excreted in urine samples of the general population. To investigate the internal
Liming Wang et al.
The Journal of clinical investigation, 125(5), 1913-1926 (2015-04-07)
Familial forms of focal segmental glomerulosclerosis (FSGS) have been linked to gain-of-function mutations in the gene encoding the transient receptor potential channel C6 (TRPC6). GPCRs coupled to Gq signaling activate TRPC6, suggesting that Gq-dependent TRPC6 activation underlies glomerular diseases. Here
Sung Wan Ham et al.
Journal of vascular surgery, 60(1), 143-150 (2014-03-07)
The objective of this study was to evaluate long-term outcome of renal revascularization by ex vivo renal artery reconstruction for complex renal artery disease. From 1987 to 2012, 23 patients (17 women; mean age, 45 years) with complex renal artery lesions underwent
E Zini et al.
Journal of veterinary internal medicine, 29(2), 589-596 (2015-03-31)
Cats with diabetes mellitus can have subclinical pancreatitis but prospective studies to confirm this are lacking. Metabolic control of diabetic cats with pancreatitis is difficult. Subclinical pancreatitis occurs in diabetic cats at the time diabetes is diagnosed or might develop
Michael Mazzeffi et al.
Journal of cardiothoracic and vascular anesthesia, 29(2), 360-366 (2014-12-17)
It was hypothesized that preoperative hyponatremia is associated with increased 30-day mortality after left ventricular assist device placement, and that large increases in sodium concentration are associated with adverse neurologic events and 30-day mortality. Data were collected retrospectively on all
Shasank Rijal et al.
The American journal of cardiology, 115(8), 1107-1110 (2015-02-24)
Nonfunctional or recalled cardiac implantable electronic device leads can be revised with either lead extraction (LE) or lead capping (LC). Factors that influence this decision and comparative outcomes of these strategies are unclear. We reviewed data from our institution to
Hakan Uçar et al.
Angiology, 65(9), 806-811 (2013-10-01)
Increased aortic stiffness (AS) has been shown to be an independent risk factor for cardiovascular disease in renal failure and was also found to be associated with even mild renal insufficiency. We investigated the relationship between contrast-induced nephropathy (CIN) and
Márcio Galindo Kiuchi et al.
Journal of clinical hypertension (Greenwich, Conn.), 16(11), 794-800 (2014-10-09)
Twenty-seven patients with resistant hypertension and chronic kidney disease were treated by renal sympathetic denervation (RSD) and followed for 12 months. Patients were retrospectively divided into controlled and uncontrolled blood pressure (BP) groups. Increases in mean estimated glomerular filtration rate
Dominique Joly et al.
Diabetes research and clinical practice, 108(1), 120-127 (2015-03-03)
Type 2 diabetes (T2D) and chronic kidney disease (CKD) are closely linked. This study aimed to describe and analyze the relations between renal function and glycemic control in T2D patients with overt nephropathy. Data were collected from a French observational
E S Ford
European journal of clinical nutrition, 69(5), 572-578 (2014-08-15)
To explore the associations between serum concentrations of vitamin D (25(OH)D) and all-cause mortality among US adults defined by lung function (LF) status, particularly among adults with obstructive LF (OLF). Data from 10,795 adults aged 20-79 years (685 with restrictive
Rahel S Spindler et al.
Transplantation, 99(5), 935-941 (2015-02-13)
This study investigated the potential use of N-octanoyl dopamine (NOD) in donor management to ameliorate the damage caused by brain death and ischemia-reperfusion injury in a rat model of kidney and heart transplantation. Brain-dead Fisher rats were treated for 6
Cariton Kubwabo et al.
Analytical and bioanalytical chemistry, 406(18), 4381-4392 (2014-05-13)
Bisphenol A (BPA) is a widely used industrial chemical in the manufacturing of polycarbonate plastic bottles, food and beverage can linings, thermal receipts, and dental sealants. Animal and human studies suggest that BPA may disrupt normal hormonal function and hence
Ie A Hudz' et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(2), 45-51 (2013-07-03)
With the introduction of doxorubicin into mice with Lewis carcinoma in the heart and liver tissues and kidney the organ-antitoxic effects of N-stearoilethanolamine (NSE) were found, which depended on its concentration. Administration of doxorubicin to male mice leads to an
Matthew P Rubach et al.
PLoS pathogens, 11(3), e1004655-e1004655 (2015-03-13)
Decreased bioavailability of nitric oxide (NO) is a major contributor to the pathophysiology of severe falciparum malaria. Tetrahydrobiopterin (BH4) is an enzyme cofactor required for NO synthesis from L-arginine. We hypothesized that systemic levels of BH₄ would be decreased in
Alberto Thalison Silveira et al.
Environmental toxicology and pharmacology, 48, 191-196 (2016-11-07)
In the present study, we investigated the influence of diazepam (DZP) on the excretion of TOL by examining their urinary metabolites, hippuric acid (HA) and ortho-cresol (o-C). Male Wistar rats were exposed to TOL (20ppm) in a nose-only exposure chamber
Anke Raaijmakers et al.
Blood pressure, 24(5), 275-283 (2015-06-25)
The microvasculature and macrovasculature undergo extensive, organ-specific perinatal maturation. Multiple studies show associations between low birth weight and subsequent cardiovascular dysfunction in adulthood, suggesting that extreme preterm birth interferes with this maturation process. Therefore, we designed PREMATCH (PREMATurity as predictor
Mandy Oplinger et al.
The Annals of pharmacotherapy, 47(1), 106-111 (2013-01-24)
To investigate the evidence leading to nitrofurantoin contraindication in patients with a creatinine clearance (CrCl) below 60 mL/min. Literature was searched in PubMed (1965-June 2012) by using the key words and MeSH terms urinary tract infections-drug therapy, chronic kidney insufficiency
F M Germaschewski et al.
Osteoarthritis and cartilage, 22(5), 690-697 (2014-03-04)
To characterise ARGS neoepitope concentrations in various matrices from patients with knee osteoarthritis (OA) and assess performance of an immunoassay to facilitate clinical development of therapeutics affecting the A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) pathway. Matched sera
Li Wang et al.
Experimental biology and medicine (Maywood, N.J.), 239(10), 1310-1324 (2014-06-01)
Astragaloside IV (AS-IV) is a major active ingredient from Radix astragali, which has been considered as a renoprotective agent; however, its molecular mechanisms are unclear. Thus, we designed to investigate the renoprotective effects and mechanisms of AS-IV in rat model
Meredith C Foster et al.
Clinical journal of the American Society of Nephrology : CJASN, 10(11), 1956-1963 (2015-09-10)
Liver fatty acid binding protein (L-FABP), kidney injury molecule 1 (KIM-1), N-acetyl-β-d-glucosaminidase (NAG), and neutrophil gelatinase-associated lipocalin (NGAL) are urinary markers of tubular injury that may also be markers of chronic kidney damage. We evaluated the association of these markers
Evan L Pannkuk et al.
Radiation research, 184(2), 121-133 (2015-08-01)
Due to concerns surrounding potential large-scale radiological events, there is a need to determine robust radiation signatures for the rapid identification of exposed individuals, which can then be used to guide the development of compact field deployable instruments to assess
Yao-Jun Zhang et al.
Chinese medical journal, 128(6), 714-720 (2015-03-12)
Studies have suggested that use of prolonged dual antiplatelet therapy (DAPT) following new generation drug-eluting stent implantation may increase costs and potential bleeding events. This study aimed to investigate the association of DAPT status with clinical safety in patients undergoing
P I Burgess et al.
Diabetic medicine : a journal of the British Diabetic Association, 31(12), 1643-1650 (2014-05-16)
To report the prevalence of all grades of diabetic retinopathy and associations with demographic, clinical and biochemical variables in people with diabetes in Southern Malawi. We report baseline data from a 24-month prospective cohort study. Subjects were systematically sampled from
Chong-Jing Gao et al.
Environmental pollution (Barking, Essex : 1987), 203, 1-6 (2015-04-05)
Benzophenone (BP)-type UV filters are commonly used in our daily life. 2-hydroxy-4-methoxy benzophenone (BP-3), 4-hydroxy benzophenone (4-HBP), 2,4-dihydroxy benzophenone (BP-1), 2,2',4,4'-tetrahydroxy benzophenone (BP-2) and 2,2'-dihydroxy-4-methoxy benzophenone (BP-8) were measured in urine samples from Chinese young adults. The results indicated that
I-Jen Wang et al.
Environmental research, 136, 213-218 (2014-12-03)
Phthalate exposure may increase the risk of atopic disorders. However, little is known about the joint effects of phthalate exposure and filaggrin (FLG) gene variants on atopic dermatitis (AD). We want to investigate whether FLG variants are related to a
Hai-Guang Xin et al.
Molecular and cellular biochemistry, 392(1-2), 117-124 (2014-03-22)
In hypertensive animals and patients, oxidative stress represents the primary risk factor for progression of renal disease. Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant
Mihály Tapolyai et al.
Journal of clinical hypertension (Greenwich, Conn.), 16(12), 895-899 (2014-10-21)
The authors examined the relationship between thiazide-type diuretics and fluid spaces in a cohort of hypertensive patients in a retrospective study of 60 stable hypertensive patients without renal abnormalities who underwent whole-body bioimpedance analysis. Overhydration was greater in the diuretic
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