搜索范围
C4407
应用筛选条件
关键词:'C4407'
显示 1-30 #N/A 183 条结果 关于 "C4407" 范围 论文
Camila Martos Thomazini et al.
PLoS neglected tropical diseases, 15(9), e0009715-e0009715 (2021-09-04)
Patients bitten by snakes consistently manifest a bleeding tendency, in which thrombocytopenia, consumption coagulopathy, mucous bleeding, and, more rarely, thrombotic microangiopathy, are observed. Von Willebrand factor (VWF) is required for primary hemostasis, and some venom proteins, such as botrocetin (a
Akiko Nagaishi et al.
Nihon rinsho. Japanese journal of clinical medicine, 71(5), 876-880 (2013-06-20)
Patients with myasthenia gravis(MG) are divided into three groups: (1) acetylcholine receptor antibody positive MG: 80%, (2) muscle-specific receptor tyrosine kinase (MuSK) antibody positive MG: 5-10%, and (3) double seronegative MG. In 2011, autoantibodies (Abs) against low-density lipoprotein receptor-related protein
Rahul Gawri et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(9), 1189-1197 (2014-05-28)
Presently, there are no established treatments to prevent, stop or even retard back pain arising from disc degeneration. Previous studies have shown that Link N can act as a growth factor and stimulate the synthesis of proteoglycans and collagens, in
Joe Swift et al.
Science (New York, N.Y.), 341(6149), 1240104-1240104 (2013-08-31)
Tissues can be soft like fat, which bears little stress, or stiff like bone, which sustains high stress, but whether there is a systematic relationship between tissue mechanics and differentiation is unknown. Here, proteomics analyses revealed that levels of the
Meng Hu et al.
The Journal of pharmacology and experimental therapeutics, 351(1), 87-95 (2014-07-23)
Myofibroblasts are effector cells in fibrotic disorders that synthesize and remodel the extracellular matrix (ECM). This study investigated the role of the Src kinase pathway in myofibroblast activation in vitro and fibrogenesis in vivo. The profibrotic cytokine, transforming growth factor
Discussion.
Surgery, 156(4), 908-909 (2014-09-23)
Xiaomin He et al.
Journal of nanoscience and nanotechnology, 13(6), 3818-3825 (2013-07-19)
Electrospinning has recently received much attention, showing great potential as a novel scaffold fabrication method for cartilage tissue engineering. In this study, we developed a biodegradable hybrid nanofibrous membrane of collagen and poly(L-lactic acid-co-epsilon-caprolactone) (PLCL, 75:25) by electrospinning for cartilage
Wei Chen et al.
Human pathology, 45(1), 160-165 (2013-12-11)
During progression from normal liver to cirrhosis, total collagen increases nearly 10-fold with an abnormal increase in fibril-forming collagen and other extracellular matrix molecules. However, little is known regarding the changes each collagen type undergoes during fibrogenesis. We assessed the
Katarina Wolf et al.
The Journal of cell biology, 201(7), 1069-1084 (2013-06-27)
Cell migration through 3D tissue depends on a physicochemical balance between cell deformability and physical tissue constraints. Migration rates are further governed by the capacity to degrade ECM by proteolytic enzymes, particularly matrix metalloproteinases (MMPs), and integrin- and actomyosin-mediated mechanocoupling.
Emily Hams et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 367-372 (2013-12-18)
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for interleukin (IL)-25 in the generation of
E Tong et al.
Journal of wound care, 23(7), 355-357 (2014-07-22)
Reconstruction of large abdominal wall defects is a challenging procedure, often contraindicated in critically ill patients, with high incidences of complications. We present a case of a patient with a large abdominal wall defect who had reconstruction with MatriDerm® (an
David Lu et al.
The Journal of biological chemistry, 288(26), 19040-19049 (2013-05-17)
The establishment of set points for cellular activities is essential in regulating homeostasis. Here, we demonstrate key determinants of the fibrogenic set point of cardiac fibroblasts (CFs) by focusing on the pro-fibrotic activity of ATP, which is released by CFs.
David Tabibian et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(12), 855-857 (2014-12-02)
To report the use of accelerated photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL) as a first-line treatment in a patient with an atypical fungal keratitis. Case report and literature review. A patient who presented with a painful peripheral corneal infiltrate
M K Murphy et al.
Journal of dental research, 92(8), 753-758 (2013-06-21)
The frequency and impact of temporomandibular joint (TMJ) disorders necessitate research in characterizing the joint's function. The 6 discal attachments have not yet been systematically characterized under tension. Understanding their role in joint function may guide our study of TMJ
Yan Bi et al.
American journal of physiology. Cell physiology, 307(7), C622-C633 (2014-08-01)
Hepatic stellate cells (HSCs) generate matrix, which in turn may also regulate HSCs function during liver fibrosis. We hypothesized that HSCs may endocytose matrix proteins to sense and respond to changes in microenvironment. Primary human HSCs, LX2, or mouse embryonic
SuRak Eo et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 68(1), 104-112 (2014-12-03)
Fifteen rabbits were used to assess the effect of Lipo-PGE1 on neovascularization. Merocel(®) and Alloderm(®) of the same size were implanted separately under the back skin to act as matrices for vessel growth. Lipo-PGE1 was injected intravenously for 2 weeks
Arianna Carolina Rosa et al.
The Journal of pharmacology and experimental therapeutics, 351(2), 308-316 (2014-09-04)
Pulmonary fibrosis, a progressive and lethal lung disease characterized by inflammation and accumulation of extracellular matrix components, is a major therapeutic challenge for which new therapeutic strategies are warranted. Cyclooxygenase (COX) inhibitors have been previously utilized to reduce inflammation. Histamine
Georgios Kotsakis et al.
The Journal of oral implantology, 40(6), 690-698 (2014-12-17)
It has been documented that after every extraction of one or more teeth, the alveolar bone of the respective region undergoes resorption and atrophy. Therefore, ridge preservation techniques are often employed after tooth extraction to limit this phenomenon. The benefits
Tomohiro Tanaka et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1370-1379 (2014-01-24)
Formation of proper neuromuscular connections is a process coordinated by both motoneuron-intrinsic and target-dependent programs. Under these programs, motoneurons innervate target muscles, escape programmed cell death during fetal development, and form neuromuscular junctions (NMJ). Although a number of studies have
High fluence iontophoretic corneal collagen cross-linking: in vivo OCT imaging of riboflavin penetration.
Paolo Vinciguerra et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(6), 376-377 (2013-06-07)
Nwanmegha Young et al.
The Annals of otology, rhinology, and laryngology, 123(11), 765-768 (2014-06-21)
The predictability of laryngeal cancer spread is due in part to connective tissue membranes. These membranes function as barriers to cancer and divide the larynx into subunits. The field of laryngeal conservation surgery is based on these concepts. The quadrangular
Shaun D Mendenhall et al.
Plastic and reconstructive surgery, 135(1), 29e-42e (2014-12-30)
Use of acellular dermal matrix in tissue expander breast reconstruction has become a popular adjunct to the total submuscular technique. The question remains as to which matrix, if any, is ideal for breast reconstruction. A randomized trial was conducted to
Johana Hrdinova et al.
International journal of molecular sciences, 23(4) (2022-02-27)
The plasmatic von Willebrand factor (VWF) circulates in a compact form unable to bind platelets. Upon shear stress, the VWF A1 domain is exposed, allowing VWF-binding to platelet glycoprotein Ib-V-IX (GPIbα chain). For a better understanding of the role of
Eun Young Hwang et al.
Biochemical and biophysical research communications, 449(4), 425-431 (2014-05-27)
Periostin appears to be a unique extracellular protein secreted by fibroblasts that is upregulated following injury to the heart or changes in the environment. Periostin has the ability to associate with other critical extracellular matrix (ECM) regulators such as TGF-β
Atul Katarkar et al.
Biochemical and biophysical research communications, 456(3), 707-713 (2014-12-20)
Heat shock protein-47 (Hsp-47) is exclusive collagen specific molecular chaperone involved in the maturation, processing and secretion of procollagen. Hsp-47 is consistently upregulated in several fibrotic diseases. Till date there is no potential antifibrotic small molecule drug available and Hsp-47
Visian toric ICL implantation for residual refractive errors after ICRS implantation and corneal collagen cross-linking in keratoconus.
Elias Jarade et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(7), 444-444 (2013-07-04)
Marjan M Tajrishi et al.
Biochemical and biophysical research communications, 446(4), 1219-1224 (2014-04-01)
Progressive loss of skeletal muscle mass and strength (sarcopenia) is a major clinical problem in the elderly. Recently, proinflammatory cytokine TWEAK and its receptor Fn14 were identified as key mediators of muscle wasting in various catabolic states. However, the role
Solfrid J Sagstad et al.
American journal of physiology. Heart and circulatory physiology, 308(1), H29-H38 (2014-11-02)
Collagen and glycosaminoglycans (GAGs) constituting the ECM may limit the space available and thus exclude macromolecules from a fraction of the interstitial fluid (IF) phase. This exclusion phenomenon is of importance for transcapillary fluid and solute exchange. The purpose of
Sirintip Chaichalotornkul et al.
Biochemical and biophysical research communications, 456(1), 92-97 (2014-12-03)
Secondhand cigarette smoke exposure (SSE) has been linked to carcinogenic, oxidative, and inflammatory reactions. Herein, we investigated whether premature skin aging could be induced by SSE in a rat model, and assessed the cytoplasmic translocation of high mobility group box
Caroline Forsell et al.
The Annals of thoracic surgery, 98(1), 65-71 (2014-06-03)
The prevalence for thoracic aortic aneurysms (TAAs) is significantly increased in patients with a bicuspid aortic valve (BAV) compared with patients who have a normal tricuspid aortic valve (TAV). TAA rupture is a life-threatening event, and biomechanics-based simulations of the
1/7