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关键词:'C4888'
显示 1-30 共 120 条结果 关于 "C4888" 范围 论文
Dobrin D Draganov et al.
Journal of translational medicine, 17(1), 100-100 (2019-03-29)
Previous studies have identified IFNγ as an important early barrier to oncolytic viruses including vaccinia. The existing innate and adaptive immune barriers restricting oncolytic virotherapy, however, can be overcome using autologous or allogeneic mesenchymal stem cells as carrier cells with
Richard L Johnson et al.
Environmental science & technology, 47(3), 1573-1580 (2013-01-15)
The fate of nano zerovalent iron (nZVI) during subsurface injection was examined using carboxymethylcellulose (CMC) stabilized nZVI in a very large three-dimensional physical model aquifer with detailed monitoring using multiple, complementary detection methods. A fluorescein tracer test in the aquifer
Daming Zhou et al.
Cell, 184(9), 2348-2361 (2021-03-18)
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began when the first sequence was published, and this forms the basis for vaccines currently deployed globally. Independent lineages of SARS-CoV-2 have recently been reported: UK, B.1.1.7;
M Keshavarz et al.
Pharmaceutical development and technology, 19(8), 952-959 (2013-10-29)
The rheological and drug release behavior of biopolymer nanocomposite gels based on the cellulose derivatives, formulated as the bioadhesive drug delivery platforms, were investigated. The bioadhesive gel is composed of the microcrystalline cellulose, sodium carboxymethyl cellulose and phosphate buffered saline
Durbadal Ojha et al.
Viruses, 13(11) (2021-11-28)
A number of viruses, including Herpes Simplex Virus (HSV), West Nile Virus (WNV), La Crosse Virus (LACV), Zika virus (ZIKV) and Tick-borne encephalitis virus (TBEV), have the ability to gain access to the central nervous system (CNS) and cause severe
A Bhattacharya
Pakistan journal of biological sciences : PJBS, 16(24), 2036-2040 (2014-02-13)
Quantity of extracellular proteins and activities two cell wall degrading enzymes pectinase and cellulase were determined in the culture filtrate of Fusarium solani, the causal organism of root rot of Coleus forskohlii. Substitution of carbon source in the medium with
Shazia Bashir et al.
Diseases of the colon and rectum, 56(10), 1174-1184 (2013-09-12)
Little is known about the use and toxicity of antiadhesion substances such as sodium hyaluronate-carboxymethylcellulose. We analyzed the patterns of use and safety of sodium hyaluronate-carboxymethylcellulose in patients undergoing colectomy and gynecologic surgery. This is a retrospective cohort study. This
Kasim Caglayan et al.
American journal of surgery, 208(1), 106-111 (2014-05-13)
We aimed to compare the effectiveness of linezolid in preventing intraperitoneal adhesions with hyaluronic acid + carboxymethylcellulose (Seprafilm). Thirty rats were divided randomly into 3 groups: Group I (control), untreated; Group II (Seprafilm); and Group III (linezolid). All rats were
Ian F Pollack et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(19), 2050-2058 (2014-06-04)
Diffuse brainstem gliomas (BSGs) and other high-grade gliomas (HGGs) of childhood carry a dismal prognosis despite current treatments, and new therapies are needed. Having identified a series of glioma-associated antigens (GAAs) commonly overexpressed in pediatric gliomas, we initiated a pilot
Christopher P Horoszko et al.
The journal of physical chemistry. C, Nanomaterials and interfaces, 123(39), 24200-24208 (2020-07-22)
The semiconducting single-walled carbon nanotube (SWCNT), noncovalently wrapped by a polymeric monolayer, is a nanoscale semiconductor-electrolyte interface under investigation for sensing, photonics, and photovoltaic applications. SWCNT complexes are routinely observed to sensitize various electrochemical/redox phenomena, even in the absence of
Kevin R Bewley et al.
Nature protocols, 16(6), 3114-3140 (2021-04-25)
Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the plaque reduction neutralization test (PRNT) is considered the gold standard for measuring levels of these antibodies for many viral diseases. We have developed procedures for the standard PRNT
B S Graham et al.
Mucosal immunology, 3(5), 475-486 (2010-06-18)
Mucosal immunization may be important for protection against pathogens whose transmission and pathogenesis target the mucosal tissue. The capsid proteins of human papillomavirus (HPV) confer tropism for the basal epithelium and can encapsidate DNA during self-assembly to form pseudovirions (PsVs).
Hanyu Yang et al.
Frontiers in neuroscience, 14, 45-45 (2020-03-07)
Chronic neuroinflammation is of great importance in the pathogenesis of Parkinson's disease (PD). During the process of neuroinflammation, overactivated microglia release many proinflammatory factors, which eventually induce neurodegeneration. Inhibition of excessive microglial activation is regarded as a promising strategy for
Lihua Cheng et al.
PloS one, 6(9), e25433-e25433 (2011-10-04)
Cisplatin is a potent anticancer drug, but its clinical application has been limited due to its undesirable physicochemical characteristics and severe side effects. Better drug formulations for cisplatin are highly desired. Herein, we have developed a nanoparticle formulation for cisplatin
David L Horn et al.
The Annals of otology, rhinology, and laryngology, 123(12), 852-858 (2014-06-26)
This study aimed to investigate the role of interarytenoid injection laryngoplasty (IL) for the management of pediatric aspiration. Medical records of 30 patients, 9 female, with radiographically confirmed chronic aspiration who underwent intraoperative IL were retrospectively reviewed. Clinical improvement was
Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in
Reply: To PMID 23665729.
Monica Panca et al.
Journal of wound care, 22(11), 646-648 (2013-11-30)
Nicholas J Hunt et al.
ACS nano, 15(3), 4710-4727 (2021-02-26)
Orally administered Ag2S quantum dots (QDs) rapidly cross the small intestine and are taken up by the liver. Metformin and nicotinamide mononucleotide (NMN) target metabolic and aging processes within the liver. This study examined the pharmacology and toxicology of QD-based
Timothy Notton et al.
mBio, 12(1) (2021-01-21)
It has long been known that noncoding genomic regions can be obligate cis elements acted upon in trans by gene products. In viruses, cis elements regulate gene expression, encapsidation, and other maturation processes, but mapping these elements relies on targeted
Maintaining skin integrity in patients with incontinent episodes.
Catherine T Milne
Ostomy/wound management, 59(2), 10-10 (2013-03-22)
Wanwisa Dejnirattisai et al.
Cell, 184(11), 2939-2954 (2021-04-15)
Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. However, new strains have emerged with multiple mutations, including P.1 from Brazil, B.1.351 from South Africa, and B.1.1.7
Peter Abbink et al.
Nature medicine, 24(6), 721-723 (2018-06-06)
Strategies to treat Zika virus (ZIKV) infection in dengue virus (DENV)-endemic areas are urgently needed. Here we show that a DENV-specific antibody against the E-dimer epitope (EDE) potently cross-neutralizes ZIKV and provides robust therapeutic efficacy as well as prophylactic efficacy
Donna Z Bliss et al.
Research in nursing & health, 37(5), 367-378 (2014-08-27)
Dietary fiber supplements are used to manage fecal incontinence (FI), but little is known about the fiber type to recommend or the level of effectiveness of such supplements, which appears related to the fermentability of the fiber. The aim of
Wanwisa Dejnirattisai et al.
Cell, 184(8), 2183-2200 (2021-03-24)
Antibodies are crucial to immune protection against SARS-CoV-2, with some in emergency use as therapeutics. Here, we identify 377 human monoclonal antibodies (mAbs) recognizing the virus spike and focus mainly on 80 that bind the receptor binding domain (RBD). We
'Clinical and cost-effectiveness of absorbent dressings in the treatment of highly exuding VLUs'.
Stephen Bishop et al.
Journal of wound care, 22(11), 644-644 (2013-11-15)
Lindsay A Wegiel et al.
Pharmaceutical development and technology, 19(8), 976-986 (2013-11-07)
We have investigated the physical stability of amorphous curcumin dispersions and the role of curcumin-polymer intermolecular interactions in delaying crystallization. Curcumin is an interesting model compound as it forms both intra and intermolecular hydrogen bonds in the crystal. A structurally
Eric A Shikatani et al.
PloS one, 7(10), e46625-e46625 (2012-10-12)
The angiostatic nature of pharmacological doses of glucocorticoid steroids is well known. However, the consequences of pathophysiological elevation of endogenous glucocorticoids are not well established. In the current study, we hypothesized that the angiostatic effect of corticosterone, an endogenous glucocorticoid
Chris M Kocur et al.
Journal of contaminant hydrology, 145, 17-25 (2012-12-25)
Nano-scale zero valent iron (nZVI) has received significant attention because of its potential to rapidly reduce a number of priority source zone contaminants. In order to effectively deliver nZVI to the source zone the nZVI particles must be stable. Previous
Ramesh Sharma et al.
Carbohydrate polymers, 92(2), 1546-1554 (2013-02-13)
Polyion-counterion interactions in sodium carboxymethylcellulose-ethylene glycol-water ternary system have been investigated with special reference to their variations with the polyelectrolyte concentration, the medium relative permittivity and the temperature using electrical conductance measurements. The experimental data have been analyzed on the
S S Olmez et al.
Die Pharmazie, 68(2), 110-116 (2013-03-09)
In this study, clozapine orally disintegrating tablets (ODTs) were prepared by direct compression method. Disintegration time, resistance to crushing of tablets, porosity, friability, dissolution tests were performed and dissolution profiles of ODTs were investigated. Morphological and interaction studies were also
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