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关键词:'C5013'
显示 1-30 共 98 条结果 关于 "C5013" 范围 论文
KangJu Lee et al.
Acta biomaterialia, 80, 48-57 (2018-09-30)
There are increasing demands for long-term and controlled corneal drug delivery to treat various ocular diseases. Although biodegradable ocular inserts or contact lenses have been developed, the invasiveness and inefficiency of the approaches still need to be improved. Microneedle (MN)
Richard L Johnson et al.
Environmental science & technology, 47(3), 1573-1580 (2013-01-15)
The fate of nano zerovalent iron (nZVI) during subsurface injection was examined using carboxymethylcellulose (CMC) stabilized nZVI in a very large three-dimensional physical model aquifer with detailed monitoring using multiple, complementary detection methods. A fluorescein tracer test in the aquifer
Yuri M Shlyapnikov et al.
Analytical chemistry, 86(4), 2082-2089 (2014-01-23)
Magnetic beads (MB) are widely used for quick and highly sensitive signal detection in microarray-based assays. However, this technique imposes stringent requirements for smoothness and adhesive properties of the surface, which most common substrates do not satisfy. We report here
M Keshavarz et al.
Pharmaceutical development and technology, 19(8), 952-959 (2013-10-29)
The rheological and drug release behavior of biopolymer nanocomposite gels based on the cellulose derivatives, formulated as the bioadhesive drug delivery platforms, were investigated. The bioadhesive gel is composed of the microcrystalline cellulose, sodium carboxymethyl cellulose and phosphate buffered saline
A Bhattacharya
Pakistan journal of biological sciences : PJBS, 16(24), 2036-2040 (2014-02-13)
Quantity of extracellular proteins and activities two cell wall degrading enzymes pectinase and cellulase were determined in the culture filtrate of Fusarium solani, the causal organism of root rot of Coleus forskohlii. Substitution of carbon source in the medium with
David L Horn et al.
The Annals of otology, rhinology, and laryngology, 123(12), 852-858 (2014-06-26)
This study aimed to investigate the role of interarytenoid injection laryngoplasty (IL) for the management of pediatric aspiration. Medical records of 30 patients, 9 female, with radiographically confirmed chronic aspiration who underwent intraoperative IL were retrospectively reviewed. Clinical improvement was
Jitendra Kumar et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 45(4), 330-335 (2010-04-20)
Controlled release (CR) formulations of metribuzin in Polyvinyl chloride [(PVC) (emulsion)], carboxy methyl cellulose (CMC), and carboxy methyl cellulose-kaolinite composite (CMC-KAO), are reported. Kinetics of its release in water and soil was studied in comparison with the commercial formulation (75
Donna Z Bliss et al.
Research in nursing & health, 37(5), 367-378 (2014-08-27)
Dietary fiber supplements are used to manage fecal incontinence (FI), but little is known about the fiber type to recommend or the level of effectiveness of such supplements, which appears related to the fermentability of the fiber. The aim of
Maintaining skin integrity in patients with incontinent episodes.
Catherine T Milne
Ostomy/wound management, 59(2), 10-10 (2013-03-22)
Susanta Pahari et al.
Autophagy, 16(6), 1021-1043 (2019-08-30)
Host-directed therapies are gaining considerable impetus because of the emergence of drug-resistant strains of pathogens due to antibiotic therapy. Therefore, there is an urgent need to exploit alternative and novel strategies directed at host molecules to successfully restrict infections. The
Shazia Bashir et al.
Diseases of the colon and rectum, 56(10), 1174-1184 (2013-09-12)
Little is known about the use and toxicity of antiadhesion substances such as sodium hyaluronate-carboxymethylcellulose. We analyzed the patterns of use and safety of sodium hyaluronate-carboxymethylcellulose in patients undergoing colectomy and gynecologic surgery. This is a retrospective cohort study. This
Kasim Caglayan et al.
American journal of surgery, 208(1), 106-111 (2014-05-13)
We aimed to compare the effectiveness of linezolid in preventing intraperitoneal adhesions with hyaluronic acid + carboxymethylcellulose (Seprafilm). Thirty rats were divided randomly into 3 groups: Group I (control), untreated; Group II (Seprafilm); and Group III (linezolid). All rats were
Ian F Pollack et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(19), 2050-2058 (2014-06-04)
Diffuse brainstem gliomas (BSGs) and other high-grade gliomas (HGGs) of childhood carry a dismal prognosis despite current treatments, and new therapies are needed. Having identified a series of glioma-associated antigens (GAAs) commonly overexpressed in pediatric gliomas, we initiated a pilot
Adam B Roberts et al.
Molecular pharmacology, 84(2), 208-217 (2013-05-22)
Bacterial β-glucuronidases expressed by the symbiotic intestinal microbiota appear to play important roles in drug-induced epithelial cell toxicity in the gastrointestinal (GI) tract. For the anticancer drug CPT-11 (irinotecan) and the nonsteroidal anti-inflammatory drug diclofenac, it has been shown that
Zachary R Crook et al.
Journal of molecular biology, 432(14), 3989-4009 (2020-04-19)
The impenetrability of the blood-brain barrier (BBB) to most conventional drugs impedes the treatment of central nervous system (CNS) disorders. Interventions for diseases like brain cancer, neurodegeneration, or age-associated inflammatory processes require varied approaches to CNS drug delivery. Cystine-dense peptides
Shannah K Witchey et al.
Neurotoxicology, 74, 139-148 (2019-06-30)
Bisphenol A (BPA) is a well-characterized endocrine disrupting chemical (EDC) used in plastics, epoxy resins and other products. Neurodevelopmental effects of BPA exposure are a major concern with multiple rodent and human studies showing that early life BPA exposure may
Lihua Cheng et al.
PloS one, 6(9), e25433-e25433 (2011-10-04)
Cisplatin is a potent anticancer drug, but its clinical application has been limited due to its undesirable physicochemical characteristics and severe side effects. Better drug formulations for cisplatin are highly desired. Herein, we have developed a nanoparticle formulation for cisplatin
Reply: To PMID 23665729.
Monica Panca et al.
Journal of wound care, 22(11), 646-648 (2013-11-30)
Sherry A Ferguson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 140(2), 374-392 (2014-05-07)
The developing central nervous system may be particularly sensitive to bisphenol A (BPA)-induced alterations. Here, pregnant Sprague Dawley rats (n = 11-12/group) were gavaged daily with vehicle, 2.5 or 25.0 μg/kg BPA, or 5.0 or 10.0 μg/kg ethinyl estradiol (EE2)
Aijun Zhang et al.
PloS one, 10(11), e0142634-e0142634 (2015-11-17)
Indirubin, a traditional Chinese medicine, is used to treat autoimmune diseases in clinics. However, the effects of indirubin on the immunosuppressive CD4+CD25+Foxp3+ regulatory T cells (Treg) have not been addressed. Thus, we aimed to investigate the effects of indirubin on
J M Görlach et al.
Applied and environmental microbiology, 64(2), 385-391 (1998-02-17)
Mixed-linked glucanases (MLGases), which are extracellular enzymes able to hydrolyze beta 1,3-1,4-glucans (also known as mixed-linked glucans or cereal beta-glucans), were identified in culture filtrates of the plant-pathogenic fungus Cochliobolus carbonum. Three peaks of MLGase activity, designated Mlg1a, Mlg1b, and
Shafiqul I Chowdhury et al.
Vaccines, 9(1) (2021-01-17)
The bovine respiratory disease complex (BRDC) remains a major problem for both beef and dairy cattle industries worldwide. BRDC frequently involves an initial viral respiratory infection resulting in immunosuppression, which creates a favorable condition for fatal secondary bacterial infection. Current
Chris M Kocur et al.
Journal of contaminant hydrology, 145, 17-25 (2012-12-25)
Nano-scale zero valent iron (nZVI) has received significant attention because of its potential to rapidly reduce a number of priority source zone contaminants. In order to effectively deliver nZVI to the source zone the nZVI particles must be stable. Previous
Sheryl E Arambula et al.
Neurotoxicology, 63, 33-42 (2017-09-12)
Bisphenol A (BPA) is a high volume endocrine disrupting chemical found in a wide variety of products including plastics and epoxy resins. Human exposure is nearly ubiquitous, and higher in children than adults. Because BPA has been reported to interfere
Deepmoni Deka et al.
Preparative biochemistry & biotechnology, 43(3), 256-270 (2013-02-06)
An extracellular alkaline carboxymethycellulase (CMCase) from Bacillus subtilis was purified by salt precipitation followed by anion-exchange chromatography using DEAE-Sepharose. The cell-free supernatant containing crude enzyme had a CMCase activity of 0.34 U/mg. The purified enzyme gave a specific activity of
Sathya N Thulasi Raman et al.
Emerging microbes & infections, 9(1), 2046-2060 (2020-09-03)
Zika virus (ZIKV) infection is a serious public threat with cases reported in about 70 countries and territories. One of the most serious consequences of ZIKV infection is congenital microcephaly in babies. Congenital microcephaly has been suggested to result from
Jiangsheng Zhou et al.
Carbohydrate polymers, 207, 729-736 (2019-01-03)
ChiEn3 from Coprinopsis cinerea was characterized as an exo-acting chitinase with a processivity. ChiEn3 hydrolyzed only soluble chitin and exhibited a hyperhydrolytic activity toward 85% deacetylated chitosan which was 33.6-fold higher than its hydrolytic activity toward glycol chitin. Its maximum
Ayhan Savaşer et al.
Pharmaceutical development and technology, 18(5), 1122-1130 (2012-08-14)
Metoclopramide HCl (MTC) is commonly used for the management of gastrointestinal disorders. It has a short biological half-life and is usually administered four times daily to maintain effective concentrations throughout the day. The aim of this study is to develop
Wai-Hong Wu et al.
Virology journal, 12, 140-140 (2015-09-13)
Infection by any one of 15 high risk human papillomavirus (hrHPV) types causes most invasive cervical cancers. Their oncogenic genome is encapsidated by L1 (major) and L2 (minor) coat proteins. Current HPV prophylactic vaccines are composed of L1 virus-like particles
B M Moron et al.
Caries research, 47(2), 162-170 (2012-12-14)
This study compared dentine demineralization induced by in vitro and in situ models, and correlated dentine surface hardness (SH), cross-sectional hardness (CSH) and mineral content by transverse microradiography (TMR). Bovine dentine specimens (n = 15/group) were demineralized in vitro with
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