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Jing Xu et al.
Molecular microbiology, 89(5), 929-948 (2013-07-09)
Many bacteria colonize surfaces and transition to a sessile mode of growth. The plant pathogen Agrobacterium tumefaciens produces a unipolar polysaccharide (UPP) adhesin at single cell poles that contact surfaces. Here we report that elevated levels of the intracellular signal
Julien Duboisset et al.
The journal of physical chemistry. B, 117(3), 784-788 (2013-01-08)
Amyloid fibrils are protein misfolding structures that involve a β-sheet structure and are associated with the pathologies of various neurodegenerative diseases. Here we show that Thioflavine-T and Congo Red, two major dyes used to image fibrils by fluorescence assays, can
Nibaldo C Inestrosa et al.
Current Alzheimer research, 2(3), 301-306 (2005-06-25)
The cholinergic system impairment observed in Alzheimer's disease (AD) patients leads to the cognitive, global and behavioral dysfunction commonly associated with dementia. The only treatment for AD has been the use of inhibitors of acetylcholinesterase (AChE) (E.C. 3.1.1.7), which is
Hideyo Inouye et al.
Sub-cellular biochemistry, 38, 203-224 (2005-02-16)
We consider here the chemistry of Congo red (CR), its binding equilibrium to Alzheimer's beta-amyloid, and the kinetics of beta-amyloid formation. Spectroscopic UV/V is measurements for the pH- and time-dependence binding of CR to Abeta analogues are analysed by Scatchard
M W Oli et al.
Microbiology (Reading, England), 158(Pt 12), 2903-2916 (2012-10-20)
Dental caries is a common infectious disease associated with acidogenic and aciduric bacteria, including Streptococcus mutans. Organisms that cause cavities form recalcitrant biofilms, generate acids from dietary sugars and tolerate acid end products. It has recently been recognized that micro-organisms
Alexander J Howie et al.
Micron (Oxford, England : 1993), 40(3), 285-301 (2008-11-21)
Amyloid stained by Congo red has striking optical properties that generally have been poorly described and inadequately explained, although they can be understood from principles of physical optics. Molecules of Congo red are orientated on amyloid fibrils, and so the
Colin Charnock
Microorganisms, 9(1) (2021-01-07)
Plastic pollution has become one of the most critical environmental issues, as rapidly increasing production, compounded by persistence of plastic wastes in the environment, are outpacing efforts to keep ecosystems plastic-free. A switch to plastics more amenable to microbial attack
Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.
Wilcock DM, et al.
Nature Protocols, 1, 1591-1591 (2006)
Marta Vergara-Irigaray et al.
Infection and immunity, 77(9), 3978-3991 (2009-07-08)
Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains that produce either a polysaccharide intercellular adhesin/poly-N-acetylglucosamine
Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Chemical Engineering Journal, 148, 354-364 (2009)
Thaís Dias Lemos Kaiser et al.
Diagnostic microbiology and infectious disease, 75(3), 235-239 (2013-01-15)
Staphylococcus epidermidis in immunocompromised patients can cause bacteremia related to the use of catheter due to biofilm production. There are different phenotypic methods to detect biofilm formation. One method is based on culture in brain heart infusion agar (BHIA) containing
Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay.
Klunk WE, et al.
Analytical Biochemistry, 266, 66-66 (1999)
K Dehvari et al.
Current medicinal chemistry, 19(30), 5199-5204 (2012-12-15)
Magnetic nanocomposites (MNCs) have highly been acknowledged in the diagnostics and therapeutic applications. Particularly, the multifunctional MNCs have brought a variety of possibilities in targeted drug delivery as well as non-invasive multimodality imaging. A temperature-responsive magnetic drug delivery system has
Craig B Stevens et al.
Bioorganic & medicinal chemistry letters, 23(6), 1703-1706 (2013-02-14)
3,3',4,4'-Tetrahydroxybiphenyl and three isomeric 3,3″,4,4″-tetrahydroxyterphenyls with varying geometries around the central phenyl ring have been synthesized and evaluated for their in vitro activity against aggregation of Alzheimer's amyloid-β peptide (Aβ). Results from Congo red spectral-shift assays reveal that all four
Aabgeena Naeem et al.
PloS one, 8(1), e54061-e54061 (2013-01-24)
The misfolding and aggregation of proteins is involved in some of the most prevalent neurodegenerative disorders. The importance of human serum albumin (HSA) stems from the fact that it is involved in bio-regulatory and transport phenomena. Here the effect of
Lisa Kappel et al.
PLoS pathogens, 16(2), e1008320-e1008320 (2020-02-23)
Fungal parasitism depends on the ability to invade host organisms and mandates adaptive cell wall remodeling to avoid detection and defense reactions by the host. All plant and human pathogens share invasive strategies, which aid to escape the chitin-triggered and
Jianjun Qiao et al.
Orphanet journal of rare diseases, 7, 95-95 (2012-12-14)
Amyloidosis cutis dyschromica is a rarely documented variant of cutaneous amyloidosis. To date, only 26 cases have been reported. The purpose of this study was to improve the clinical and histopathological data for this variant of amyloidosis and to highlight
Henry N Otoo et al.
Eukaryotic cell, 7(5), 776-782 (2007-12-18)
The cell wall-bound Als adhesins of Candida albicans mediate both yeast-to-host tissue adherence and yeast aggregation. This aggregation is amyloid-like, with self-propagating secondary-structure changes, amyloid-characteristic dye binding, and induced birefringence (J. M. Rauceo, N. K. Gaur, K. G. Lee, J.
Cecilia G Clement et al.
Human pathology, 45(8), 1766-1772 (2014-06-18)
Congo red stain apple-green birefringence under polarized light is the most popular method for detecting amyloid; however, it has limitations. The goal of this study was to evaluate if examination of Congo red stain by fluorescent microscopy (FM) significantly enhances
Nikolaos N Louros et al.
FEBS letters, 588(1), 52-57 (2013-11-14)
Isolated atrial amyloidosis (IAA) is a common localized form of amyloid deposition within the atria of the aging heart. The main constituents of amyloid fibrils are atrial natriuretic peptide (ANP) and the N-terminal part of its precursor form (NT-proANP). An
Shudan Wang et al.
Theranostics, 10(15), 6854-6874 (2020-06-20)
Repeated failures of "Aβ-lowering" therapies call for new targets and therapeutic approaches for Alzheimer's disease (AD). We propose to treat AD by halting neuronal death and repairing synapses using a BDNF-based therapy. To overcome the poor druggability of BDNF, we
Biomedicine. Proteins and a pregnancy woe.
Nadia Whitehead
Science (New York, N.Y.), 345(6194), 249-249 (2014-07-19)
Olga Blifernez-Klassen et al.
Nature communications, 3, 1214-1214 (2012-11-22)
Plants convert sunlight to biomass, which is primarily composed of lignocellulose, the most abundant natural biopolymer and a potential feedstock for fuel and chemical production. Cellulose assimilation has so far only been described for heterotrophic organisms that rely on photosynthetically
Christina S Faherty et al.
PloS one, 7(11), e49980-e49980 (2012-11-21)
Shigella flexneri is a Gram-negative, facultative intracellular pathogen that causes millions of cases of watery or bloody diarrhea annually, resulting in significant global mortality. Watery diarrhea is thought to arise in the jejunum, and subsequent bloody diarrhea occurs as a
Some changes in potato chips during frying observed by confocal laser scanning microscopy (CLSM).
Pedreschi F and Aguilera JM
Food Science and Technology International = Ciencia y tecnologia de Los Alimentos Internacional, 8, 197-201 (2002)
Jintae Lee et al.
Applied and environmental microbiology, 75(6), 1703-1716 (2009-01-27)
SdiA is a homolog of quorum-sensing regulators that detects N-acylhomoserine lactone (AHL) signals from other bacteria. Escherichia coli uses SdiA to reduce its biofilm formation in the presence of both AHLs and its own signal indole. Here we reconfigured SdiA
Carmen Herrero de Dios et al.
Fungal genetics and biology : FG & B, 50, 21-32 (2012-11-15)
MAPK pathways are conserved and complex mechanisms of signaling in eukaryotic cells. These pathways mediate adaptation to different stress conditions by a core kinase cascade that perceives changes in the environment by different upstream elements and mediates adaptation through transcription
Z Pourramezan et al.
Mikrobiologiia, 81(6), 796-802 (2013-04-25)
The aim of the present study was to isolate and characterize the cellulose-degrading bacteria from the gut of the local termite, Microcerotermes diversus (Silvestri), inhabiting the Khuzestan province of Iran. The microorganisms capable of growing in the liquid medium containing
Lixia Wang et al.
Dalton transactions (Cambridge, England : 2003), 42(7), 2572-2579 (2012-12-12)
A facile low-temperature hydrothermal process to synthesize α-Fe/Fe(3)O(4) nanocomposite is reported. TEM and HRTEM revealed that the α-Fe/Fe(3)O(4) nanocomposite was composed of catenulate α-Fe and lamellar structured Fe(3)O(4). The weight ratio of α-Fe in the α-Fe/Fe(3)O(4) nanocomposite is 35.6%. The
Vasilios A Sakkas et al.
Journal of hazardous materials, 175(1-3), 33-44 (2009-11-26)
The use of chemometric methods such as response surface methodology (RSM) based on statistical design of experiments (DOEs) is becoming increasingly widespread in several sciences such as analytical chemistry, engineering and environmental chemistry. Applied catalysis, is certainly not the exception.
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