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[The effect of antioxidant on the growth and lipid composition of Saccharomyces cerevisiae yeasts at different phases of the development of a culture].
O A Reshetnik et al.
Izvestiia Akademii nauk. Seriia biologicheskaia, (2)(2), 172-176 (1997-03-01)
K Van Den Houwe et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(7), 1261-1269 (2017-05-18)
Contaminants in food packaging are a challenge of our time since the packaging material itself has been found to represent a source of food contamination through the migration of substances from it. Before first use, packaging materials destined for the
Synthesis and biological evaluation of 2,6-di-tert-butylphenol hydrazones as 5-lipoxygenase inhibitors.
A M Cuadro et al.
Bioorganic & medicinal chemistry, 6(2), 173-180 (1998-04-21)
Jörg Ahrens et al.
Anesthesia and analgesia, 99(1), 91-96 (2004-07-30)
The anesthetic propofol (2,6 diisopropylphenol) mediates some of its effects by activating inhibitory chloride currents in the lower brainstem and spinal cord. The effects comprise direct activation of gamma-aminobutyric acid-A and glycine receptors in the absence of the natural agonist
Juan Ruiz et al.
Bioorganic & medicinal chemistry, 11(19), 4207-4216 (2003-09-03)
The dual or selective ability of 24 derived mono- and 2,6-di-tert-butylphenols (DTBP) to act as inhibitors of cyclooxygenase (COX) and/or 5-lipoxygenase (LOX) enzymes is investigated. Firstly, we explored the conformational variability of the compounds. It is found that dual inhibitors
Murat Sentürk et al.
Bioorganic & medicinal chemistry, 17(8), 3207-3211 (2009-02-24)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II, with a series of phenol derivatives was investigated by using the esterase assay, with 4-nitrophenyl acetate as substrate. 2,6-Dimethylphenol, 2,6-diisopropylphenol (propofol), 2,6-di-t-butylphenol, butylated hydroxytoluene, butylated
[Compounds with juvenile hormone activity. XVI. The activity of 4-substituted 2,6-di-tert-butylphenols].
N L Sergovskaia et al.
Meditsinskaia parazitologiia i parazitarnye bolezni, (1)(1), 30-34 (1984-01-01)
Jörg Ahrens et al.
Pharmacology, 83(2), 95-98 (2008-12-10)
Modulation of inhibitory synaptic transmission within the central nervous system contributes considerably to the anaesthetic effects of propofol and its analogues in vivo. We have studied the effects of the non-anaesthetic propofol analogue 2,6-di-tert-butylphenol on rat alpha(1)beta(2)gamma(2) GABA(A) receptors expressed
Zhen-wei Fang et al.
Huan jing ke xue= Huanjing kexue, 25(3), 98-101 (2004-08-26)
A degrading bacterial strain F-3-4 for 2,6-Di-tert-butylphenol (2,6-DTBP) was isolated from biofilm in acrylic fiber wastewater treatment structures. By acclimation, its capacity for degradation of 2,6-DTBP was enhanced by 26%. It was identified as Alcaligenes sp. according to morphological, physiological
Wei-Chan Cui et al.
Insect biochemistry and molecular biology, 97, 31-39 (2018-04-27)
Plant volatiles are vital cues in the location of hosts for feeding and oviposition for Lepidoptera moths. The noctuid Helicoverpa assulta is a typical polyphagous moth, regarded as a good model for studying the olfactory reception of plant volatiles. In
Alfred O Inman et al.
Toxicology in vitro : an international journal published in association with BIBRA, 17(3), 289-292 (2003-06-05)
DBNP (2,6-di-tert-butyl-4-nitrophenol) has been reported as a potential contaminant in submarines. This yellow substance forms when lubrication oil mist containing the antioxidant additive 2,6-di-tert-butylphenol passes through an electrostatic precipitator and is nitrated. Percutaneous absorption of 14C-DBNP was assessed in the
[Regulation by an antioxidant of growth, composition, and physico-chemical features of lipids from Saccharomyces cerevisiae].
O A Reshetnik et al.
Doklady Akademii nauk, 346(5), 705-707 (1996-02-01)
E R Milaeva et al.
Journal of inorganic biochemistry, 102(5-6), 1348-1358 (2008-03-07)
The novel metalloporphyrins (M=HH, Fe, Mn, Co, Cu, Zn) bearing 2,6-di-tert-butylphenol pendants as antioxidant substituents, and a long chain hydrocarbon palmitoyl group have been synthesized. The oxidation of compounds by PbO2 leads to the formation of the corresponding 2,6-di-tert-butylphenoxyl radicals
Caitlin E Cornell et al.
Biophysical journal, 113(6), 1200-1211 (2017-08-13)
A persistent challenge in membrane biophysics has been to quantitatively predict how membrane physical properties change upon addition of new amphiphiles (e.g., lipids, alcohols, peptides, or proteins) in order to assess whether the changes are large enough to plausibly result
Studies on the synthesis and anti-inflammatory activity of 2,6-di-tert-butylphenols with a heterocyclic group at the 4-position. V. Elimination reaction of the sulfinyl group of 2,3-dihydroimidazo[2,1-b]thiazole 1-oxide.
Y Isomura et al.
Chemical & pharmaceutical bulletin, 32(12), 4726-4730 (1984-12-01)
A W Girotti et al.
Lipids, 22(6), 401-408 (1987-06-01)
The effects of singlet oxygen- and oxygen radical-induced lipid peroxidation on cell membrane integrity were compared, using the human erythrocyte ghost as a model system. Resealed ghosts underwent lipid peroxidation and lysis (release of trapped glucose-6-P) when irradiated in the
Mehmet Tümer et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(3), 477-481 (2007-09-07)
Crystals of the 3,3'-5,5'-tetra-tert-butyl-4,4'-diphenoquinone (TTBDQ) in the reaction mixture DCM/MeOH (1:1, v/v) were obtained as a result of CC coupling reaction of the sterically hindered phenol (2,6-di-tert-butylphenol, DTBP) using the binuclear Co(II) complexes. The oxidation product (TTBDQ), C(28)H(40)O(2), crystallizes in
Stanley J Stachelek et al.
Journal of biomedical materials research. Part A, 82(4), 1004-1011 (2007-03-21)
Polyurethane cardiovascular implants are subject to oxidation initiated surface degradation, which is mediated by monocyte-derived macrophages (MDM); this often leads to surface cracking and device failure. The present studies examined the hypothesis that covalently attaching antioxidant, di-tert-butylphenol (DBP), to the
Y Fujimoto et al.
The Journal of pharmacy and pharmacology, 36(3), 195-197 (1984-03-01)
The inhibitory effects of NN'-diphenyl-p-phenylenediamine (DPPD), sodium diethyldithiocarbamate (SDDC) and 2,6-di-t-butylphenol (DTBP) on the generation of medullary prostaglandin E have been compared. DPPD (1 microM) and SDDC (1 mM) failed to inhibit arachidonic acid-induced stimulation of prostaglandin E synthesis, while
Masahiro Ogata et al.
Chemical & pharmaceutical bulletin, 53(3), 344-346 (2005-03-04)
This study was carried out to investigate the antioxidant activity of propofol (2,6-diisopropylphenol) and its related compounds, butylated hydroxyanisole (BHA), 2,6-dimethylphenol, 2,6-di-t-butylphenol, and their dimeric compounds. The degree of antioxidant activity was evaluated based on the degree of peroxidation induced
Shinsuke Ishihara et al.
Journal of the American Chemical Society, 133(40), 16119-16126 (2011-08-31)
Porphyrin derivatives bearing 2,6-di-tert-butylphenol substituents at their 5,15-positions undergo reversible photoredox switching between porphyrin and porphodimethene states as revealed by UV-vis spectroscopy, fluorescence spectroscopy, and X-ray single-crystal analyses. Photoredox interconversion is accompanied by substantial variations in electronic absorption and fluorescence
Ya-lei Zhang et al.
Journal of environmental sciences (China), 17(2), 271-275 (2005-11-22)
An aerobic bacterium strain, F-3-4, capable of effectively degrading 2, 6-ditert-butylphenol (2, 6-DTBP), was isolated and screened out from an acrylic fiber wastewater and the biofilm in the wastewater treatment facilities. This strain was identified as Alcaligenes sp. through morphological
J B Kramer et al.
Bioorganic & medicinal chemistry, 3(4), 403-410 (1995-04-01)
The preparation of hydroxylamine analogs of 2,6-di-tert-butylphenols (DTBP) and the inhibition of cyclooxygenase (CO) and 5-lipoxygenase (5-LO) by these compounds is discussed.
Studies on the synthesis and anti-inflammatory activity of 2,6-di-tert-butylphenols with a heterocyclic group at the 4-position. II.
Y Isomura et al.
Chemical & pharmaceutical bulletin, 31(9), 3179-3185 (1983-09-01)
[Studies on the synthesis of anti-inflammatory activity of 2,6-di-tert-butylphenols with a heterocyclic group at the 4-position. IV. Photo-induced and base-catalyzed oxygenation of 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxo-4-imidazolines].
Y Isomura et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 104(8), 909-914 (1984-08-01)
2,6-di-tert-butylphenols: a new class of potent and selective PGHS-2 inhibitor.
Y Song et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 46 Suppl 2, S141-S142 (1997-08-01)
George N Ziakas et al.
Bioorganic & medicinal chemistry, 14(16), 5616-5624 (2006-05-13)
Amine or amide derivatives bearing the 2,6-di-tert-butyl phenol moiety are synthesised. Almost all are antioxidants, reduce acute inflammation and inhibit COX-1 and lipoxygenase activity. The most potent anti-inflammatory, COX-1 inhibitor and antioxidant agent, with low toxicity, is 2,6-di-tert-butyl-4-thiomorpholin-4-ylmethyl-phenol.
Anouar Hafiane et al.
The Canadian journal of cardiology, 35(6), 770-781 (2019-06-04)
Small peptides based on the C-terminal domain of apo E have recently been proposed as ATP-binding cassette transporter A1 (ABCA1) agonist with therapeutic potential. Previous work has shown that a novel synthetic peptide, CS-6253, acts synergistically with apolipoprotein A-I or
Cynthia D Selassie et al.
Journal of medicinal chemistry, 48(23), 7234-7242 (2005-11-11)
In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop the following
G Haeseler et al.
European journal of anaesthesiology, 20(3), 220-224 (2003-03-26)
Propofol is a phenol derivative (2,6 di-isopropylphenol) with a unique effect profile including activating effects on GABA(A) and blocking effects on voltage-operated sodium channels. If the substituents in the 2- and the 6-positions are replaced by tert-butyl groups, the resulting
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