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显示 1-30 共 92 条结果 关于 "D9143" 范围 论文
Rufeng Xie et al.
International immunopharmacology, 55, 98-104 (2017-12-15)
Red cell-derived microparticles (RMPs) are potential mediators of transfusion-related acute lung injury (TRALI). The aim of this study was to investigate the effects of microparticles present in red cell concentrates (RCC) on polymorphonuclear neutrophil (PMN) respiratory burst and acute lung
Tsong-Long Hwang et al.
Bioorganic & medicinal chemistry, 23(5), 1123-1134 (2015-02-05)
Proteinase 3 (Pr3), and human neutrophil elastase (HNE) are two major neutrophilic serine proteases (NsPs) expressed in neutrophil azurophil granules. Emerging data suggest that excessive release of proteases mediates tissue damage, and therefore prolonged neutrophil accumulation has an important role
J Wang et al.
Journal of animal science, 93(4), 1679-1688 (2015-05-29)
Polyamines are necessary for normal integrity and the restitution after injury of the gastrointestinal epithelium. The objective of this study was to investigate the effects of oral administration of putrescine and proline during the suckling period on epithelial restitution after
Fumihiko Katakura et al.
Developmental and comparative immunology, 53(1), 13-22 (2015-06-27)
The use of in vitro colony assays in mammals has contributed to identification of erythroid progenitor cells such as burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) progenitors, and serves to examine functions of erythropoietic growth factors like Erythropoietin (Epo) and
Arseima Y Del Valle-Pinero et al.
World journal of gastroenterology, 21(1), 155-163 (2015-01-13)
To investigate the vasoactive intestinal peptides (VIP) expression in irritable bowel syndrome (IBS) and trinitrobenzene sulfonic acid (TNBS) induced colitis. The VIP gene expression and protein plasma levels were measured in adult participants (45.8% male) who met Rome III criteria
Miray Sahinkaya et al.
Molecular biology reports, 46(1), 569-580 (2018-11-27)
A newly identified ligninolytic Rhodococcus strain (Rhodococcus sp. T1) was isolated from forestry wastes (Trabzon/Turkey). The DyP type peroxidase of Rhodococcus sp. T1 (DyPT1) was cloned, characterized and paper treated for industrial applications. Molecular weight of the protein was about
Jui-Yang Lai et al.
PloS one, 10(8), e0136067-e0136067 (2015-08-22)
Hyaluronic acid (HA) is a linear polysaccharide naturally found in the eye and therefore is one of the most promising biomaterials for corneal endothelial regenerative medicine. This study reports, for the first time, the development of overrun-processed porous HA hydrogels
3,3'-Dimethoxybenzidine and dyes metabolized to 3,3'-dimethoxybenzidine: 3,3'-dimethoxybenzidine.
Report on carcinogens : carcinogen profiles, 12, 164-165 (2011-08-20)
S Torres-Cartas et al.
European journal of medicinal chemistry, 42(11-12), 1396-1402 (2007-05-08)
Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry and their mutagenic capacity. Biopartitioning micellar chromatography (BMC), a mode of micellar liquid
Patrudu Makena et al.
Environmental and molecular mutagenesis, 48(5), 404-413 (2007-03-21)
4-Aminobyphenyl (4-Ab), benzidine (Bz), and Bz congeners were evaluated for their ability to induce genotoxicity through an oxidative mechanism. The mutagenicity of these compounds was tested in the presence and absence of Aroclor 1254-induced rat S9 mix using Salmonella typhimurium
D M Lehmann et al.
Access microbiology, 1(10), e000065-e000065 (2020-09-26)
Honey is a natural product with many beneficial properties including antimicrobial action. Production of hydrogen peroxide (H2O2) in diluted honey is central to this action. Here, we describe an optimized method for measuring levels of H2O2 in honey. This method
Irina Pozdnyakova et al.
Biochimica et biophysica acta, 1804(4), 740-744 (2009-11-26)
Enzymes catalyze biochemical reactions in highly crowded environments where the amount of macromolecules may occupy up to 40% of the volume. Here we report how cell-like conditions tune catalytic parameters for the monomeric multi-copper oxidase, Saccharomyces cerevisiae Fet3p, in vitro.
Iain S MacPherson et al.
Protein engineering, design & selection : PEDS, 23(3), 137-145 (2010-01-20)
Directed evolution methods were developed for Cu-containing nitrite reductase (NiR) from Alcaligenes faecalis S-6. The PCR cloning strategy allows for the efficient production of libraries of 100 000 clones by a modification of a megaprimer-based whole-plasmid synthesis reaction. The high-throughput
Costanza Giampietro et al.
Nature communications, 6, 8479-8479 (2015-10-09)
Vascular lumen formation is a fundamental step during angiogenesis; yet, the molecular mechanisms underlying this process are poorly understood. Recent studies have shown that neural and vascular systems share common anatomical, functional and molecular similarities. Here we show that the
Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish
Lieschke GJ, et al.
Blood, 98(10), 3087-3096 (2001)
C Flavia Massaro et al.
Journal of agricultural and food chemistry, 62(50), 12209-12217 (2014-11-26)
Australian stingless bee honeys have been shown to exert antioxidant and in vitro antimicrobial properties; however their bioactive factors remained unidentified. This study investigated the antibacterial properties of phenolic extracts from Tetragonula carbonaria honeys. Honeys were harvested from beehives in
Tingfang Yi et al.
Nature communications, 6, 7194-7194 (2015-05-29)
MicroRNA (miRNA) biogenesis and miRNA-guided RNA interference (RNAi) are essential for gene expression in eukaryotes. Here we report that translation initiation factor eIF1A directly interacts with Ago2 and promotes Ago2 activities in RNAi and miR-451 biogenesis. Biochemical and NMR analyses
Ye Bu et al.
Journal of cell science, 127(Pt 12), 2761-2770 (2014-04-15)
Protein tyrosine phosphatases (PTPs) are involved in hematopoiesis, but the function of many PTPs is not well characterized in vivo. Here, we have identified Ptpn9a, an ortholog of human PTPN9, as a crucial regulator of erythroid cell development in zebrafish
Jason Ear et al.
Blood, 126(7), 880-890 (2015-06-26)
Diamond-Blackfan Anemia (DBA) is a bone marrow failure disorder characterized by low red blood cell count. Mutations in ribosomal protein genes have been identified in approximately half of all DBA cases. Corticosteriod therapy and bone marrow transplantation are common treatment
Verónica Ramírez-Alcántara et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G1002-G1010 (2014-04-20)
Pharmacotherapy based on 5-aminosalicylic acid (5-ASA) is a preferred treatment for ulcerative colitis, but variable patient response to this therapy is observed. Inflammation can affect therapeutic outcomes by regulating the expression and activity of drug-metabolizing enzymes; its effect on 5-ASA
Uta Merle et al.
Journal of hepatology, 51(5), 925-930 (2009-09-02)
A low serum ceruloplasmin concentration is considered diagnostic for Wilson's disease. We aimed to evaluate an enzymatic test for ceruloplasmin oxidase activity and to compare it with the routinely used immunological ceruloplasmin measurement. Serum ceruloplasmin was measured enzymatically with o-dianisidine
Hulya Toker et al.
Journal of periodontal research, 47(5), 572-577 (2012-03-01)
The aim of this study was to evaluate the impact of smoking on the relationship between interleukin-1 (IL-1β) and oxidation in patients with periodontitis and response to nonsurgical periodontal therapy. Data were obtained from 30 patients with generalized chronic periodontitis
Kashima Arora et al.
The Analyst, 139(18), 4606-4612 (2014-07-22)
The development of a noninvasive test for uric acid has been the holy grail of uric acid detection research over the last decade. In the present work, a novel matrix comprising of a NiO thin film (a biocompatible material) loaded
Francesca Pintus et al.
Biochemistry, 49(40), 8739-8747 (2010-09-09)
The oxidation of the pseudohalide thiocyanate (SCN(-)) by Euphorbia peroxidase, in the presence or absence of added calcium, is investigated. After incubation of the native enzyme with hydrogen peroxide, the formation of Compound I occurs and serves to catalyze the
Luiz G Reys et al.
Life sciences, 92(13), 783-792 (2013-02-27)
Trauma/hemorrhagic shock (T/HS) induced gut injury is known to initiate a systemic inflammatory response which can lead to secondary lung injury. We have shown that vagal nerve stimulation (VNS) protects intestinal epithelial integrity after a severe burn insult. We hypothesize
Elena García-Martín et al.
Clinical biochemistry, 40(16-17), 1339-1341 (2007-09-11)
Serum diamine oxidase (DAO; EC 1.4.3.6) activity is often employed as a clinical indicator of the integrity of intestinal mucosa. However, interindividual variation in enzyme activity and reference values for healthy women and men have not been studied. DAO activity
Wei-He Qian et al.
International journal of molecular medicine, 44(2), 569-581 (2019-06-08)
Alcoholic hepatitis (AH) is a fatal inflammatory syndrome with no effective treatments. Intestinal injury and intestinal endotoxemia (IETM) contribute greatly in the development of AH. MicroRNAs (miRNAs/miRs) have been reported to affect intestinal injury. The present study aims to investigate
A Stančić et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(10), 1432-1445 (2015-08-01)
G protein-coupled receptor 55 (GPR55) is a lysophospholipid receptor responsive to certain cannabinoids. The role of GPR55 in inflammatory processes of the gut is largely unknown. Using the recently characterized GPR55 inhibitor CID16020046, we determined the role of GPR55 in experimental
Nidhi Goyal et al.
Pharmacological reports : PR, 67(3), 616-623 (2015-05-03)
Ulcerative colitis is a chronic inflammatory condition in which the inflammatory response confined to the colon. There is a need to explore the new targets for UC such as Farnesoid X receptor and hydrogen sulfide pathway. Wistar rats of either
Jenny P Castro et al.
Biological research, 47, 32-32 (2014-09-11)
Despite Cryptostegia grandiflora Roxb. ex R. Br. (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Therefore, this work aimed to evaluate the effect of the
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