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Copper rewired.
Nature, 508(7495), 150-150 (2014-04-12)
J F Carroll et al.
Journal of medical entomology, 51(3), 629-637 (2014-06-06)
Behavioral bioassays remain a standard tool in the discovery, development, and registration of arthropod repellents. Tick repellent bioassays are generally uncomplicated, but their results can be affected by basic variables (e.g., dimensions of testing materials, substrate, timing, temperature) of the
A N Elias et al.
Journal of clinical gastroenterology, 4(2), 137-139 (1982-04-01)
The mechanisms responsible for the genesis of pseudo-Cushing's syndrome are poorly understood. We studied the effect of acute ethanol administration on the hypothalamic-pituitary-adrenal axis in five chronic alcoholic patients and three normal volunteers. Ethanol was administered alone and together with
Peter Stenvinkel et al.
Clinical journal of the American Society of Nephrology : CJASN, 1(2), 281-287 (2007-08-21)
Myeloperoxidase (MPO), which is secreted during activation of neutrophils, may serve as one mechanistic link among persistent inflammation, oxidative stress, and cardiovascular disease. This study related MPO activity to inflammatory and oxidative stress biomarkers, comorbidity, and ongoing medication in prevalent
Blanka Wolszczak et al.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 36(211), 45-47 (2014-03-22)
Ethyl alcohol and the products of its metabolism influence changes in the functioning of numerous tissues and organs, as well as enzymes and hormones. Alcohol causes malfunction of the hormonal pivot hypothalamus--pituitary gland--adrenal glands and hypothalamus-pituitary gland--thyroid, alcohol is harmful
J S Huang et al.
The Biochemical journal, 346 Pt 1, 241-247 (2000-02-05)
In serum-starved NIH 3T3 fibroblasts, ethanol (30-80 mM) promoted the effects of insulin and insulin-like growth factor I (IGF-I) on DNA synthesis in a Zn(2+)-dependent manner. Ethanol and Zn(2+) were most effective when added shortly before or after insulin, indicating
Felix H Lam et al.
Science (New York, N.Y.), 346(6205), 71-75 (2014-10-04)
Ethanol toxicity in the yeast Saccharomyces cerevisiae limits titer and productivity in the industrial production of transportation bioethanol. We show that strengthening the opposing potassium and proton electrochemical membrane gradients is a mechanism that enhances general resistance to multiple alcohols.
J Henriksson et al.
Acta physiologica Scandinavica, 185(4), 313-320 (2005-11-04)
The present study was performed to test the hypothesis that the interstitial glucose concentration in human skeletal muscle is decreased for a prolonged period following a single bout of exercise, while blood flow has returned to resting levels. Muscle interstitial
Jan Klimas et al.
The American journal of emergency medicine, 32(10), 1168-1173 (2014-08-27)
Opioid overdose (OD) is the primary cause of death among drug users globally. Personal and social determinants of overdose have been studied before, but the environmental factors lacked research attention. Area deprivation or presence of addiction clinics may contribute to
Driving intoxicated: is hospital admission protective against legal ramifications?
Mathew Edavettal et al.
The journal of trauma and acute care surgery, 76(5), 1335-1335 (2014-04-22)
S Meshitsuka et al.
Clinica chimica acta; international journal of clinical chemistry, 312(1-2), 25-30 (2001-10-03)
Endogenous ethanol was observed by nuclear magnetic resonance spectroscopy in the course of screening for cerebrospinal fluid of the patients with cervical myelopathy. Ethanol was detected in 10 out of 20 patients. It seems likely that the presence of endogenous
Arthur S Brecher et al.
Alcohol (Fayetteville, N.Y.), 26(1), 49-53 (2002-04-18)
The effect of low concentrations of acetaldehyde on activated partial thromboplastin time (APTT) and prothrombin time (PT) of Accuclot coagulation plasmas was monitored over a prolonged time to mimic effects observed in alcoholism. A prolongation of the APTT from 31.9
José L Báez-Escudero et al.
Journal of the American College of Cardiology, 63(18), 1892-1901 (2014-02-25)
This study sought to determine whether ethanol infusion in the vein of Marshall (VOM) can ablate intrinsic cardiac nerves (ICN). ICN cluster around the left atrial epicardium and are implicated in the genesis of atrial fibrillation (AF). Patients undergoing catheter
Irene Zelner et al.
Drug metabolism reviews, 45(3), 277-299 (2013-05-30)
The ability to undergo non-oxidative metabolism from ethanol to fatty acid ethyl esters (FAEEs) varies greatly among tissues and organs. To gain a greater understanding of non-oxidative ethanol metabolism to FAEE, we aimed to collect all published data on FAEE
S Enocksson et al.
The Journal of clinical investigation, 95(5), 2239-2245 (1995-05-01)
Although it is well established in several mammalian species that beta 3-adrenoceptors play a major role in regulating lipolysis and thermogenesis in adipose tissue, the functional existence and role of this receptor subtype in man has been controversial. We investigated
U Allenstein et al.
Soft matter, 11(25), 5053-5059 (2015-06-02)
Cells require adhesion to survive, proliferate and migrate, as well as for wound healing and many other functions. The strength of contractile cell forces on an underlying surface is a highly relevant quantity to measure the affinity of cells to
Carlos F Burgos et al.
The Journal of pharmacology and experimental therapeutics, 352(1), 148-155 (2014-10-24)
The α1-subunit containing glycine receptors (GlyRs) is potentiated by ethanol, in part, by intracellular Gβγ actions. Previous studies have suggested that molecular requirements in the large intracellular domain are involved; however, the lack of structural data about this region has
Peng Chen et al.
Gastroenterology, 148(1), 203-214 (2014-09-23)
Alcoholic liver disease is a leading cause of mortality. Chronic alcohol consumption is accompanied by intestinal dysbiosis, and development of alcoholic liver disease requires gut-derived bacterial products. However, little is known about how alterations to the microbiome contribute to pathogenesis
R Paniagua et al.
Nephron, 69(2), 147-150 (1995-01-01)
Patients with chronic renal failure often have low plasma zinc (Zn) levels. Some factors that may account for abnormal Zn metabolism in these patients are low dietary Zn intake, a specific Zn transport defect, or absence of intestinal Zn ligand.
Mingzhu Li et al.
Toxicology letters, 228(2), 67-74 (2014-04-29)
Salvianolic acid B (SalB) is isolated from the traditional Chinese medical herb salvia miltiorrhiza. It has many biological and pharmaceutical activities. This study aimed to investigate the effect of SalB on acute ethanol-induced hepatic injury in rats and to explore
M Uemura et al.
Gastroenterology, 118(6), 1140-1148 (2000-06-02)
Leukotrienes are proinflammatory mediators. Ethanol inhibits the catabolism of both cysteinyl leukotrienes (leukotriene E(4) [LTE(4)] and N-acetyl-LTE(4)) and leukotriene B(4) (LTB(4)) in hepatocytes. We examined the metabolic derangement of leukotriene inactivation by ethanol in humans in vivo. LTE(4), N-acetyl-LTE(4), LTB(4)
Li Xin Su et al.
The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA), 17(2), 85-89 (2014-12-23)
Arteriovenous malformations (AVMs) are congenital vascular malformations (CVMs) resulting from birth defects of the vasculature. It is rarely seen, only accounting for 1.5% of all vascular anomalies, and 50% of the lesions are located in the oral and maxillofacial region.
William Chan et al.
The Canadian journal of cardiology, 30(8), 912-919 (2014-07-30)
Myocardial contrast echocardiography during angiography is critical in identifying appropriate septal perforator(s) for alcohol septal ablation (ASA) in patients with hypertrophic obstructive cardiomyopathy. We evaluated whether there were other angiographic and/or echocardiographic markers that might identify patients who are anatomically
Thiago M Pais et al.
PLoS genetics, 9(6), e1003548-e1003548 (2013-06-12)
The yeast Saccharomyces cerevisiae is able to accumulate ≥17% ethanol (v/v) by fermentation in the absence of cell proliferation. The genetic basis of this unique capacity is unknown. Up to now, all research has focused on tolerance of yeast cell
Deenadayalan Purushothaman et al.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 147(1), 29-36 (2014-12-24)
Our objective was to quantitatively assess and compare the bisphenol A (BPA) released from an orthodontic adhesive using a light-emitting diode device (LED) or a halogen light-curing unit (HLC) at 3 tip-to-bracket distances (0, 5, and 10 mm) and varying
Manuel Quirós et al.
International journal of food microbiology, 181, 85-91 (2014-05-17)
Respiration of sugars by non-Saccharomyces yeasts has been recently proposed for lowering alcohol levels in wine. Development of industrial fermentation processes based on such an approach requires, amongst other steps, the identification of yeast strains which are able to grow
Annika Thorsell et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(24), 10132-10142 (2013-06-14)
The Neuropeptide S receptor, a Gs/Gq-coupled GPCR expressed in brain regions involved in mediating drug reward, has recently emerged as a candidate therapeutic target in addictive disorders. Here, we describe the in vitro and in vivo pharmacology of a novel
O D Ianieva et al.
TSitologiia i genetika, 47(6), 43-50 (2014-01-21)
The search for lactose-fermenting yeast strains has been conducted among 162 strains isolated from various plants and 28 yeast strains isolated from cheese. Four yeast strains have been shown to ferment lactose. They have been identified as Candida kefyr. Specific
Alcohol inhalation.
Bernard Le Foll et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 186(10), E399-E399 (2014-04-24)
Monika Derda et al.
Acta poloniae pharmaceutica, 70(6), 1027-1034 (2014-01-05)
Selected fractions of ethanolic extracts obtained from leaves and roots of Eryngium planum (Apiaceae) were evaluated in vitro for amebicidal activity against Acanthamoeba castellanii. This free-living ameba is the cause of Acanthamoeba keratitis, which is a painful, vision-impairing disease of
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