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A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis, Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats.
Liu, IM; Tzeng, TF; Liou, SS
Evidence-Based Complementary and Alternative Medicine : ECAM null
Increasing the fat-to-carbohydrate ratio in a high-fat diet prevents the development of obesity but not a prediabetic state in rats.
Natalia Sinitskaya, Sylviane Gourmelen, Carole Schuster-Klein et al.
Clinical Science (London, England : 1979) (1979)
The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates ?- cell insulin release.
Koren-Gluzer M, Aviram M, Meilin E, Hayek T
Atherosclerosis null
Christy M Gliniak et al.
The Journal of biological chemistry, 292(36), 15080-15093 (2017-07-25)
It has long been appreciated that insulin action is closely tied to circadian rhythms. However, the mechanisms that dictate diurnal insulin sensitivity in metabolic tissues are not well understood. Retinol-binding protein 4 (RBP4) has been implicated as a driver of
Influence of AIN-93 diet on mortality and cardiac remodeling after myocardial infarction in rats.
Lidiane P Ardisson,Marcos F Minicucci,Paula S Azevedo,Fernanda Chiuso-Minicucci et al.
International Journal of Cardiology null
Mechanism of action of the stimulatory effect of apigenin-6-C-(2''-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake.
Luisa Helena Cazarolli, Poliane Folador, Henrique Hunger Moresco et al.
Chemico-Biological Interactions null
Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet-induced metabolic syndrome.
Rueda-Clausen CF, Dolinsky VW, Morton JS, Proctor SD, Dyck JR, Davidge ST.
Diabetes null
Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats.
Jen-Hao Hsu, Yang-Chang Wu, I-Min Liu, Juei-Tang Cheng
Journal of Ethnopharmacology null
Jun-Hui Choi et al.
Scientific reports, 10(1), 21102-21102 (2020-12-05)
Previous studies have suggested that vinegar intake can help to reduce body fat and hyperglycemia. Therefore, this study aimed to evaluate the anti-obesity efficacy of vinegar fermented using Cudrania tricuspidata fruits (CTFV) and its main phenolic constituents and to analyze
S Gómez-Zorita et al.
The British journal of nutrition, 107(2), 202-210 (2011-07-08)
Non-alcoholic fatty liver disease (NAFLD) is one of the most common manifestations of chronic liver disease worldwide. The aim of the present study was to assess the effect of resveratrol on liver fat accumulation, as well as on the activity
Lene N Axelsen et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 298(6), R1560-R1570 (2010-04-02)
Metabolic syndrome and obesity-related diseases are affecting more and more people in the Western world. The basis for an effective treatment of these patients is a better understanding of the underlying pathophysiology. Here, we characterize fructose- and fat-fed rats (FFFRs)
Oshrit Ben-David et al.
The Journal of biological chemistry, 286(34), 30022-30033 (2011-06-28)
Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin. We now characterize the biochemical, histological, and behavioral abnormalities in the brain of a mouse lacking very long acyl (C22-C24) chain SLs. This mouse
Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type-2 diabetes.
Sharma S, Misra CS, Arumugam S, Roy S, Shah V, Davis JA, Shirumalla RK, Ray A
Phytotherapy Research null
Amadori-glycated phosphatidylethanolamine, a potential marker for hyperglycemia, in streptozotocin-induced diabetic rats.
Sookwong P, Nakagawa K, Fujita I, Shoji N, Miyazawa T.
Lipids null
Body composition and selected blood parameters in mice fed a combination of fibre and conjugated linoleic acid.
M Javadi, M J H Geelen, H Everts, A G Lemmens, A C Beynen
Journal of animal physiology and animal nutrition null
Marie-Béatrice Saade et al.
Endocrinology, diabetes & metabolism, 3(1), e00095-e00095 (2020-01-11)
Obesity has become a pandaemic even in children. We aimed to investigate the impact of obesity in youth on later pancreatic intrinsic nervous system (PINS) phenotype and control of insulin secretion. Young mice (5-week-old, T0 group) were fed either a
Gina Moore et al.
Mechanisms of ageing and development, 129(4), 201-206 (2008-02-26)
Werner syndrome (WS) is an autosomal recessive progeroid syndrome caused by mutations in the Werner (Wrn) gene. WS patients have increased incidence of a number of chronic conditions including insulin resistance and type 2 diabetes. Since ingestion of foods that
Yun Ning et al.
The Journal of pharmacology and experimental therapeutics, 337(1), 50-58 (2011-01-14)
In addition to its anti-ischemic and antianginal effects, ranolazine has been shown to lower hemoglobin A(1c) (HbA(1c)) in patients with coronary artery disease and diabetes. The present study was undertaken to test the hypothesis that ranolazine lowers HbA(1c) because of
Offspring metabolomic response to maternal protein restriction in a rat model of intrauterine growth restriction (IUGR).
Alexandre-Gouabau, Marie-Cecile, et al.
Journal of Proteome Research, 10, 3292-3302 (2011)
Myricetin Ameliorates Defective Post-Receptor Insulin Signaling via ?-Endorphin Signaling in the Skeletal Muscles of Fructose-Fed Rats.
Tzeng, TF; Liou, SS; Liu, IM
Evidence-Based Complementary and Alternative Medicine : ECAM null
Chronic hypoxia increases insulin-stimulated glucose uptake in mouse soleus muscle.
Gamboa JL, Garcia-Cazarin ML, Andrade FH
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
FoxO1 is involved in the antineoplastic effect of calorie restriction.
Haruyoshi Yamaza,Toshimitsu Komatsu,Saori Wakita,Carole Kijogi,Seongjoon Park et al.
Aging Cell null
Improvement of insulin sensitivity in obese Zucker rats by myricetin extracted from Abelmoschus moschatus.
I-Min Liu,Thing-Fong Tzeng,Shorong-Shii Liou,Ting-Wei Lan
Planta Medica null
Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats.
Ko Yu Liu, Yang-Chang Wu, I-Min Liu, Wen Chen Yu, Juei-Tang Cheng
Neuroscience Letters null
Low-level subchronic arsenic exposure from prenatal developmental stages to adult life results in an impaired glucose homeostasis.
Davila-Esqueda ME, Morales JM, Jimenez-Capdeville ME, De la Cruz E, Falcon-Escobedo R et al.
Experimental and Clinical Endocrinology & Diabetes null
Release of acetylcholine by Hon-Chi to raise insulin secretion in Wistar rats.
Chang-Chih Chen, I-Min Liu
Neuroscience Letters null
Influence of fasting, insulin and glucose on ghrelin in the dorsal vagal complex in rats.
Huang L, Qiu B, Yuan L, Zheng L, Li Q, Zhu S
The Journal of Endocrinology null
Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling.
Martin J Ronis, Ying Chen, Jamie Badeaux, Thomas M Badger
The Journal of Nutrition null
How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.
Wullschleger S, Sakamoto K, Johnstone L, Duce S, Fleming S, Alessi DR.
Disease models & mechanisms null
Benjamin T Bikman et al.
The Journal of biological chemistry, 287(21), 17426-17437 (2012-04-05)
Fenretinide is a synthetic retinoid that is being tested in clinical trials for the treatment of breast cancer and insulin resistance, but its mechanism of action has been elusive. Recent in vitro data indicate that fenretinide inhibits dihydroceramide desaturase, an
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