Biologics and Biosimilars Characterization

应用筛选条件

facet applications:Biologics and Biosimilars Characterization

facet applications:Large molecule HPLC

facet applications:Mass spectrometry

facet applications:Protein mass spectrometry

facet content type:Protocol

显示 61-90 共 113 条结果

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

HPLC Analysis of Isocyanates on Titan™ C18

Fast LC-MS-MS Analysis of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3

We presents a robust method for analyzing 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in serum using a multiplexed LC-MS-MS system.

Metabolites – A Serious Challenge for LC/MS Separations and Usual Detection Techniques

We offer the tools for the analysis of the metabolites; including certified reference standards, enzymes, substrates, and chromatographic products.

GC Analysis of Aldehydes (PFBOA Derivatives) in Beer on SLB®-5ms after SPME using a 65 µm PDMS/DVB Fiber

Separation of null

Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk

Here we show how LC and MS methods may be optimized using a non-toxic surrogate of the ADC, an “ADC-mimic”, that behaves very similarly to the Cys-linked ADC Adcetris (Seattle Genetics).

radiello® Diffusive Air Sampling Application - Volatile Organic Compounds (VOCs) Thermally Desorbed

Volatile organic compounds are trapped by adsorption and recovered by thermal desorption, analysis is performed by capillary gas chromatography and FID or MS detection.

GC/MS Analysis of Ethanol in Low Alcohol Beer on SUPELCOWAX® 10 after Headspace SPME using a 100 µm PDMS Fiber

GC/MS Analysis of Ethanol in Low Alcohol Beer on SUPELCOWAX® 10 after Headspace SPME using a 100 μm PDMS Fiber

Clinical Application of SPME: Analysis of VOCs in Exhaled Breath as Cancer Biomarkers

This report demonstrates the potential of solid phase microextraction as a clinical research tool for the extraction of VOCs associated with lung cancer from human breath.

Chiral LC-MS/MS of D- and L-2-Hydroxyglutaric Acid Biomarkers

We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.

Standard Methods 6040D: GC Analysis of Geosmin and 2-MIB on SLB®-5ms after SPME using 50/30 µm DVB/Carboxen/PDMS Fiber

Separation of 2-Isopropyl-3-methoxypyrazine 20 ppt; 2-Isobutyl-3-methoxypyrazine; 2-Methylisoborneol; (±)-Geosmin 10 ppt

GC Analysis of Terpenes in Hops (Cascade Variety) on Equity^®-1 after Headspace SPME using 50/30 µM DVB/CAR/PDMS Fiber

-ß-Farnesene; Humulene; γ-Muurolene; γ-Selinene; Geranyl isobutyrate; ß-Selinene; a-Muurolene; a-Selinene; γ-Cadinene; Calamenene; Δ-Cadinene; Caryophyllene oxide; Humulene oxide

Testing Food for Fipronil Contamination

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Size Exclusion Analysis of Tween-Containing IgG Formulations

In this study, we investigated the effect of adding Tween® 20 and Tween 80 on the elution of proprietary mAb 221 under size exclusion chromatography conditions.

2-Hydroxyglutarates Analysis by LCMS

Reversed phase application for the analysis of S-2-hydroxyglutaric acids and R-2-hydroxyglutaric acids by chiral LCMS, using a CHIROBIOTIC® R Column.

Online SPE/LC-MS Method for the Rapid Analysis of Thyroid Hormones in Plasma

Determination of the thyroid hormones T4, T3 and rT3 from plasma using an Ascentis Express RP-Amide cartridge to trap the analytes, and a Phenyl-Hexyl column to resolve them.

HPLC Analysis of the Monoclonal Antibody (mAb) Erbitux (Cetuximab) on BIOshell A400 Protein C4

HPLC Analysis of the Monoclonal Antibody (mAb) Erbitux (Cetuximab) on BIOshell™ A400 Protein C4

HPLC Analysis of LMW Heparin-Dalteparin and Enoxaparin Analysis on Zenix®-100

High resolution separations of low molecular weight heparin-daletparin and enoxaparin can be achived using Zenix SEC-100 columns.

LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic

SigmaMab Antibody Drug Conjugate Mimic, is a non-toxic drug mimic utilized as a standard for mass spectrometry and high performance liquid chromatography.

Acrylamide in Food

Acrylamide analysis has been a very hot topic since the chemical was identified in food in 2002 by researchers at the Swedish National Food Administration.

BIOshell™ IgG 1000 Å C4 UHPLC Column for Improved Biomacromolecule Separations

Peptide Mapping LC-MS/MS Analysis Workflow for Adalimumab

An optimized LC-MS/MS based workflow for low artifact tryptic digestion and peptide mapping of monoclonal antibody, adalimumab (Humira) using filter assisted sample preparation (FASP).

Protocol for Purification, Optional Reduction, and SEC-MS Analysis of a Monoclonal Antibody

A complete workflow for the intact and middle-up mass analysis of reduced and non-reduced monoclonal antibodies based on SEC-MS with sample preparation by protein-A affinity clean-up.

HPLC Analysis of PEG g006200

HPLC Analysis of PEG on Two Zenix® SEC-300 Columns in Tandem

LC/MS Analysis of Opioid Glucuronide Metabolites in Urine on Ascentis® Express F5 after Solid Phase Extraction (SPE) using Supel™-Select HLB

Performing a Separation with Sephadex^®

This page shows how to perform a separation with a Sephadex column from Cytiva which are Size Exclusion Chromatography media consisting of an epichlorohydrin cross-linked dextran.

Mass Spectral Column Bleed in Nitrogen-Containing Polar-Embedded HPLC Stationary Phases

GC Analysis of Terpenes in Cannabis on Equity-1 after Headspace SPME

GC Analysis of Terpenes in Cannabis on Equity®-1 after Headspace SPME using 50/30 μm DVB/CAR/PDMS Fiber

Complete Workflow for Comprehensive Cannabis Terpenes Analysis

Complete workflow for the comprehensive analysis of terpenes in cannabis

Biological Testing for Amphetamine and Methamphetamine Abuse

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

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