Fluorination

应用筛选条件

facet applications:Fluorination

显示 1-10 #N/A 19 条结果

由于氟原子电负性强、原子半径小，氟化或将氟引入化合物有望彻底改变其生物学特性。在药物研究中，经常将氟引入目标化合物中以提高生物利用度并增强其代谢稳定性。该领域已经发展出许多引入氟的策略，其中包括一些关键反应。

Fluoroamidinium salts advance acid halogenation with greater stability and no oxazolones conversion compared to chlorides.

AlPhos and [(AlPhosPd)₂•COD] for Pd-Catalyzed Fluorination

Fluorine containing aromatics (ArF) are desirable compounds with applications in medicinal chemistry and the agricultural industry.

Deoxyfluorination with 2-Pyridinesulfonyl Fluoride (PyFluor)

The prevalence of organofluorine compounds in industry and drug design necessitates the ability to introduce C–F bonds to molecules.

Diethylaminosulfur Trifluoride (DAST)

Diethylaminosulfur trifluoride (DAST) facilitates nucleophilic fluorination in selective reactions with alcohols, ketones, and other compounds.

Fluoroalkylation: Expansion of Togni Reagents

Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.

Fluorinated Azides: Click Chemistry Meets Fluorine

Fluorinated azides are a new tool that can be used to introduce fluorinated groups to molecules. These molecules can utilize click chemistry to easily add fluorinated groups.

PhenoFluor™ Deoxyfluorination Solution

PhenoFluor™ enables one-step conversion of phenols to aryl fluorides, facilitating fluorination without pre-activation.

Selectfluor™

Selectfluor™ (F-TEDA) is a mild, stable reagent for electrophilic fluorination, enhancing user-friendly fluorination reactions.

AISF: A Solid Alternative to Sulfuryl Fluoride Gas

ASIF provides bench-stable alternative to sulfuryl fluoride gas for installing SO2F functional group in organic synthesis.

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