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Manisha Agarwal et al.
American journal of respiratory cell and molecular biology, 63(5), 613-622 (2020-07-22)
Fibrosis is characterized by fibroblast activation, leading to matrix remodeling culminating in a stiff, type I collagen-rich fibrotic matrix. Alveolar epithelial cell (AEC) apoptosis is also a major feature of fibrogenesis, and AEC apoptosis is sufficient to initiate a robust
Farhat Abbas et al.
Planta, 249(1), 71-93 (2018-09-16)
Floral scent formation in Lilium 'Siberia' is mainly due to monoterpene presence in the floral profile. LoTPS1 and LoTPS3 are responsible for the formation of (±)-linalool and β-ocimene in Lilium 'Siberia'. Lilium 'Siberia' is a perennial herbaceous plant belonging to
Zhengming Gu et al.
The Journal of molecular diagnostics : JMD, 17(6), 715-721 (2015-09-01)
Broadly multiplexed molecular amplification assays offer an unprecedented ability to diagnose gastrointestinal infection in immunocompromised patients. However, little data are available to compare the performance of such systems in this population. A total of 436 stool samples were collected from
Zhaojiang Zuo et al.
Plant physiology, 180(1), 124-152 (2019-02-15)
Isoprene synthase converts dimethylallyl diphosphate to isoprene and appears to be necessary and sufficient to allow plants to emit isoprene at significant rates. Isoprene can protect plants from abiotic stress but is not produced naturally by all plants; for example
Sohee Lee et al.
Cells, 9(2) (2020-02-28)
Protein import across the endoplasmic reticulum membrane is physiologically regulated in a substrate-selective manner to ensure the protection of stressed ER from the overload of misfolded proteins. However, it is poorly understood how different types of substrates are accurately distinguished
Francisco J Meza et al.
Scientific reports, 8(1), 8570-8570 (2018-06-07)
Biosphere-atmosphere water and carbon fluxes depend on ecosystem structure, and their magnitudes and seasonal behavior are driven by environmental and biological factors. We studied the seasonal behavior of net ecosystem CO2 exchange (NEE), Gross Primary Productivity (GPP), Ecosystem Respiration (RE)
V G Ladygin
Zhurnal obshchei biologii, 63(4), 299-325 (2002-09-27)
The author discusses the current state of biochemical and genetic aspects of carotenoid biosynthesis in chloroplasts of algae and higher plants. Two ways of biosynthesis of key C5-isoperene units have been considered: 1) from acetate (C2) via mevalonic acid (C6)
Liuming Wang et al.
The Science of the total environment, 727, 138306-138306 (2020-04-25)
Ecosystem water use efficiency (WUE) is a key indicator that depicts the carbon-water coupling relationship in terrestrial ecosystems. Separating the effects of climate change and human activities to the variation in WUE are essential for water resources and ecosystem management
Y F Liao et al.
Archives of insect biochemistry and physiology, 89(3), 127-137 (2015-03-17)
Cantharidin is a biomolecule with a role in host defense that can also be used as an anticancer drug. The in vivo biosynthetic pathway for cantharidin has been the subject of debate for several decades and the mechanism is not
Priyanka Singh et al.
Phytochemistry, 177, 112451-112451 (2020-07-04)
In Ocimum kilimandscharicum, the relative volatile composition of camphor in leaves was as high as 55%, while that of eugenol in roots was 57%. These metabolites were differentially partitioned between the aerial and root tissues. Global metabolomics revealed tissue-specific biochemical
British Association of Dermatologists' guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018.
G W M Millington et al.
The British journal of dermatology, 178(1), 34-60 (2018-01-24)
Lokesh K Narnoliya et al.
BMC genomics, 18(1), 74-74 (2017-01-15)
Rose-scented geranium (Pelargonium sp.) is a perennial herb that produces a high value essential oil of fragrant significance due to the characteristic compositional blend of rose-oxide and acyclic monoterpenoids in foliage. Recently, the plant has also been shown to produce
Mengyu Liu et al.
Functional plant biology : FPB, 47(5), 425-439 (2020-04-07)
D-limonene is the main component of citrus essential oils. In the monoterpene biosynthetic pathway, geranyl diphosphate reacts with monoterpenes to form the prenyl-carbocation intermediate to produce d-limonene. In this study, d-limonene synthase (FcLS) genes were first isolated from Rongan kumquat
Xiang Li et al.
Journal of experimental botany, 68(17), 4929-4938 (2017-10-11)
The unique flavor of Citrus fruit depends on complex combinations of soluble sugars, organic acids, and volatile compounds. The monoterpene E-geraniol is an important volatile, contributing to flavor in sweet orange (Citrus sinensis Osbeck). Moreover, antifungal activity of E-geraniol has
Chuncheng Liu et al.
Culture, health & sexuality, 22(12), 1365-1381 (2019-11-09)
Stakeholder engagement is increasingly recognised and institutionalised as an essential component of HIV-related biomedical research. However, we know little about stakeholder engagement's social outcomes, such as its influence on the community it engages with, in authoritarian regimes and beyond high-income
Guo Wei et al.
Plant physiology, 172(1), 603-618 (2016-07-28)
Plant volatile organic compounds, which are generated in a tissue-specific manner, play important ecological roles in the interactions between plants and their environments, including the well-known functions of attracting pollinators and protecting plants from herbivores/fungi attacks. However, to date, there
Samapika Nandy et al.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 28(2), 701-734 (2020-08-18)
The amphibian, non-vascular, gametophyte-dominant, bio-indicator class, bryophytes; with their wide ranges of habitat have attained importance due to their promising medicinal attributions and therapeutic role; mostly aided by presence of aromatic bibenzyl and bisbybenzyl class of compounds. Bibenzyls are steroidal
Thomas Kellner et al.
Journal of clinical microbiology, 57(6) (2019-04-12)
Although enteric multianalyte syndromic panels are increasingly employed, direct comparisons with traditional methods and the inclusion of host phenotype correlations are limited. Luminex xTAG gastrointestinal pathogen panel (GPP) and culture results are highly concordant. However, phenotypic and microbiological confirmatory testing
Abhishek A Chakraborty et al.
Science (New York, N.Y.), 363(6432), 1217-1222 (2019-03-16)
Oxygen sensing is central to metazoan biology and has implications for human disease. Mammalian cells express multiple oxygen-dependent enzymes called 2-oxoglutarate (OG)-dependent dioxygenases (2-OGDDs), but they vary in their oxygen affinities and hence their ability to sense oxygen. The 2-OGDD
Junbin Zhao et al.
Global change biology, 22(12), 4028-4037 (2016-04-03)
In high-latitude regions, carbon dioxide (CO2 ) emissions during the winter represent an important component of the annual ecosystem carbon budget; however, the mechanisms that control the winter CO2 emissions are currently not well understood. It has been suggested that
Thomas Mehner et al.
Ecology, 99(6), 1463-1472 (2018-06-02)
The density of organisms declines with size, because larger organisms need more energy than smaller ones and energetic losses occur when larger organisms feed on smaller ones. A potential expression of density-size distributions are Normalized Biomass Size Spectra (NBSS), which
Kaiyu Guan et al.
Global change biology, 22(2), 716-726 (2015-10-23)
Large-scale monitoring of crop growth and yield has important value for forecasting food production and prices and ensuring regional food security. A newly emerging satellite retrieval, solar-induced fluorescence (SIF) of chlorophyll, provides for the first time a direct measurement related
Leslie C Morey
Psychological assessment, 29(10), 1302-1308 (2017-02-28)
The DSM-5 presents an Alternative Model for Personality Disorder (AMPD) recommending the assessment of impairments in core personality functions as well as clinically relevant personality traits. Although a self-report assessment instrument has been provided corresponding to the trait model proposed
C Yu et al.
Cell death & disease, 8(2), e2582-e2582 (2017-02-06)
Star-PAP is a noncanonical poly(A) polymerase and required for the expression of a select set of mRNAs. However, the pathological role of Star-PAP in cancer largely remains unknown. In this study, we observed decreased expression of Star-PAP in breast cancer
Laura Calleros et al.
Apoptosis : an international journal on programmed cell death, 11(7), 1161-1173 (2006-05-16)
Cholesterol is essential for cell viability, and homeostasis of cellular cholesterol is crucial to various cell functions. Here we examined the effect of cholesterol depletion on apoptosis and the mechanisms underlying this effect in NIH3T3 cells. We show that chronic
Indrajyoti Indra et al.
Cell reports, 30(8), 2820-2833 (2020-02-27)
We study punctate adherens junctions (pAJs) to determine how short-lived cadherin clusters and relatively stable actin bundles interact despite differences in dynamics. We show that pAJ-linked bundles consist of two distinct regions-the bundle stalk (AJ-BS) and a tip (AJ-BT) positioned
Paramita Bera et al.
Plant science : an international journal of experimental plant biology, 256, 25-38 (2017-02-09)
Floral scent composed of low molecular weight volatile organic compounds. The sweet fragrance of any evening blooming flower is dominated by benzenoid and terpenoid volatile compounds. Floral scent of Jasminum sambac (Oleaceae) includes three major benzenoid esters - benzylacetate, methylbenzoate
Jihua Wu et al.
Journal of agricultural and food chemistry, 67(25), 7087-7097 (2019-06-15)
Limonene, a cyclic monoterpene, is widely used in food and cosmetics industries as well as in agriculture. In the work described herein, employing a systematic optimization strategy, we constructed an efficient platform for producing limonene via the heterologous mevalonate pathway
Wenshuang Xie et al.
Phytochemistry, 69(14), 2539-2545 (2008-09-19)
Natural rubber, cis-1,4-polyisoprene, is a vital industrial material synthesized by plants via a side branch of the isoprenoid pathway by the enzyme rubber transferase. While the specific structure of this enzyme is not yet defined, based on activity it is
Bharati Lalhal Barsain et al.
Plant physiology and biochemistry : PPB, 154, 115-128 (2020-06-20)
Geranyl geranyl pyrophosphate synthase (GGPPS) is known to form an integral subunit of the heteromeric GPPS (geranyl pyrophosphate synthase) complex and catalyzes the biosynthesis of monoterpene in plants. Picrorhiza kurrooa Royle ex Benth., a medicinally important high altitude plant is
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