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Rui C Martins et al.
Environmental technology, 35(17-20), 2380-2388 (2014-08-26)
The presence of surfactants in wastewater composition tends to jeopardize the efficiency of the traditional aerobic treatment processes. In this regard, the application of Fenton's reaction and nanofiltration as single processes and integrated (nanofiltration followed by Fenton's process) was investigated
Joseph D Mancias et al.
Nature, 509(7498), 105-109 (2014-04-04)
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered to lysosomes for degradation, is critical in diseases such as cancer and neurodegeneration. Much of our understanding of this process has emerged from
Stuart B Krasnoff et al.
Journal of natural products, 77(7), 1685-1692 (2014-07-06)
Under iron-depleted culture conditions, the entomopathogenic fungus Metarhizium robertsii (Bischoff, Humber, and Rehner) (= M. anisopliae) produces a complex of extracellular siderophores including novel O-glycosylated and N-oxidized coprogen-type compounds as well as the known fungal siderophores N(α)-dimethylcoprogen (NADC) and dimerumic
Ramesh Kumar et al.
Environmental technology, 35(13-16), 2018-2027 (2014-06-25)
Nanofiltration (NF) of ammoniacal wastewater containing phenol and cyanide has been investigated for effective separation of these hazardous pollutants and for the subsequent downstream chemical treatment resulting in valuable by-product generation. Four different types of composite polyamide commercial NF membranes
D Cao et al.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 41(1), 27-31 (2014-03-22)
Iron is essential to life due to its unusual flexibility in serving as both an electron donor and acceptor. However, free iron can damage tissues by catalyzing the conversion of hydrogen peroxide to free-radical ions that attack lipids, proteins and
Eduard J van Beers et al.
Circulation research, 116(2), 298-306 (2014-11-08)
Patients with sickle cell disease (SCD) have markers of chronic inflammation, but the mechanism of inflammation and its relevance to patient survival are unknown. To assess the relationship between iron, inflammation, and early death in SCD. Using peripheral blood mononuclear
50 years ago in the Journal of Pediatrics: Iron metabolism in premature infants: II. Prevention of iron deficiency.
Pamela J Kling
The Journal of pediatrics, 164(4), 768-768 (2014-03-22)
Keith P West et al.
JAMA, 312(24), 2649-2658 (2014-12-24)
Maternal micronutrient deficiencies may adversely affect fetal and infant health, yet there is insufficient evidence of effects on these outcomes to guide antenatal micronutrient supplementation in South Asia. To assess effects of antenatal multiple micronutrient vs iron-folic acid supplementation on
Mary D Frame et al.
Nanotoxicology, 8(8), 867-875 (2013-09-03)
Single-walled carbon nanotubes synthesized with iron (Fe-SWCNT) or gadolinium (Gd-SWCNT) show promise as high performance multimodal contrast and drug-delivery agents. Our purpose was to evaluate potential vasoactive effects of SWCNT. Stable aqueous solutions of Fe-SWCNTs or Gd-SWCNTs were made using
Chenyan Lv et al.
Biochemistry, 53(14), 2232-2241 (2014-04-01)
From an evolutionary point of view, plant and animal ferritins arose from a common ancestor, but plant ferritin exhibits different features as compared with the animal analogue. One major difference is that the 4-fold channels naturally occurring in plant ferritin
Theodore M Flynn et al.
Science (New York, N.Y.), 344(6187), 1039-1042 (2014-05-03)
Microbial reduction of ferric iron [Fe(III)] is an important biogeochemical process in anoxic aquifers. Depending on groundwater pH, dissimilatory metal-reducing bacteria can also respire alternative electron acceptors to survive, including elemental sulfur (S(0)). To understand the interplay of Fe/S cycling
Kurinchi Selvan Gurusamy et al.
The Cochrane database of systematic reviews, 12(12), CD010640-CD010640 (2015-01-01)
Anaemia affects about a quarter of the world's population. An estimated 50% of anaemic people have anaemia due to iron deficiency. To assess the safety and efficacy of iron therapies for the treatment of adults with anaemia who are not
[Children's iron needs and how we best can protect the child's brain].
Staffan Berglund et al.
Lakartidningen, 111(11), 460-463 (2014-04-12)
Reference method for measurement of the hepatic iron concentration.
Gary M Brittenham
American journal of hematology, 90(2), 85-86 (2014-12-10)
Janneke Balk et al.
Annual review of plant biology, 65, 125-153 (2014-02-07)
Iron is an essential element for all photosynthetic organisms. The biological use of this transition metal is as an enzyme cofactor, predominantly in electron transfer and catalysis. The main forms of iron cofactor are, in order of decreasing abundance, iron-sulfur
Cecilia M Casadei et al.
Science (New York, N.Y.), 345(6193), 193-197 (2014-07-12)
Heme enzymes activate oxygen through formation of transient iron-oxo (ferryl) intermediates of the heme iron. A long-standing question has been the nature of the iron-oxygen bond and, in particular, the protonation state. We present neutron structures of the ferric derivative
Ellinor I B Peerschke et al.
American journal of clinical pathology, 142(4), 506-512 (2014-09-23)
Evaluation of anemia, particularly iron deficiency, in patients with cancer is difficult. This study examined using the hemoglobin content of reticulocytes (RET-He) to rule out iron deficiency, as defined by serum iron studies (transferrin saturation <20%, serum iron <40 μg/dL
Robert C Hider et al.
Metal ions in life sciences, 13, 229-294 (2014-01-29)
Iron is a redox active metal which is abundant in the Earth's crust. It has played a key role in the evolution of living systems and as such is an essential element in a wide range of biological phenomena, being
B Clevenger et al.
Anaesthesia, 70 Suppl 1, 20-28 (2014-12-03)
Pre-operative anaemia is a relatively common finding, affecting a third of patients undergoing elective surgery. Traditionally associated with chronic disease, management has historically focused on the use of blood transfusion as a solution for anaemia in the peri-operative period. Data
Matthew Stroh et al.
Biochemical pharmacology, 88(4), 573-583 (2013-12-24)
A popular, if not centric, approach to the study of an event is to first consider that of the simplest cause. When dissecting the underlying mechanisms governing idiopathic diseases, this generally takes the form of an ab initio genetic approach.
Don-Kyu Kim et al.
Nature medicine, 20(4), 419-424 (2014-03-25)
In response to microbial infection, expression of the defensin-like peptide hepcidin (encoded by Hamp) is induced in hepatocytes to decrease iron release from macrophages. To elucidate the mechanism by which Salmonella enterica var. Typhimurium (S. typhimurium), an intramacrophage bacterium, alters
Parenteral iron as a cause of hypophosphataemia.
Francisco J Fernández-Fernández et al.
BMJ (Clinical research ed.), 349, g4616-g4616 (2014-07-17)
Tim M Conway et al.
Nature, 511(7508), 212-215 (2014-07-11)
Dissolved iron is an essential micronutrient for marine phytoplankton, and its availability controls patterns of primary productivity and carbon cycling throughout the oceans. The relative importance of different sources of iron to the oceans is not well known, however, and
Qiu et al.
Physical review letters, 85(7), 1492-1495 (2000-09-06)
FeF (2) films are grown by the reaction of XeF (2) and SeF (6) with iron foil. The growth initially follows the Mott-Cabrera parabolic rate law, indicating that the process is diffusion limited. At a certain film thickness, however, the
Ocean chemistry: Fingerprints of a trace nutrient.
Joseph A Resing et al.
Nature, 511(7508), 164-165 (2014-07-11)
Robert F Anderson et al.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 372(2019), 20130054-20130054 (2014-06-04)
Fluxes of lithogenic material and fluxes of three palaeo-productivity proxies (organic carbon, biogenic opal and alkenones) over the past 100,000 years were determined using the (230)Th-normalization method in three sediment cores from the Subantarctic South Atlantic Ocean. Features in the
Femkje A M Jonker et al.
Journal of clinical pathology, 67(8), 717-723 (2014-06-12)
Iron deficiency is an important child health problem. Its diagnosis in areas of high infection exposure remains complicated as inflammation may interfere with the accuracy of peripheral iron markers. With this study, we aimed to validate the conventional iron markers
Shee Chien Yong et al.
Science (New York, N.Y.), 345(6201), 1170-1173 (2014-09-06)
Alkaline phosphatases play a crucial role in phosphate acquisition by microorganisms. To expand our understanding of catalysis by this class of enzymes, we have determined the structure of the widely occurring microbial alkaline phosphatase PhoX. The enzyme contains a complex
Goldie Y L Lui et al.
Molecular pharmacology, 87(3), 543-560 (2015-01-07)
Pharmacologic manipulation of metal pools in tumor cells is a promising strategy for cancer treatment. Here, we reveal how the iron-binding ligands desferrioxamine (DFO), di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC) inhibit constitutive and interleukin 6-induced activation of signal transducer and
Judith Ernst et al.
Food and nutrition bulletin, 35(4 Suppl), S198-S204 (2015-02-03)
Preliminary evidence suggests that improved nutrition early in HIV infection may delay progression to AIDS and delay the initiation or improve the effectiveness of antiretroviral drug therapy. There are few studies that evaluate food-based interventions in drug-naïve, HIV-infected women and
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