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显示 1-30 共 9366 条结果 关于 "H-100" 范围 论文
O Rosendo et al.
Journal of dairy science, 87(8), 2535-2545 (2004-08-26)
Fifty-two multiparous Holstein cows were randomly assigned to receive 0 or 20 mg of biotin/d starting at an average of 16 d prepartum and then switched to 0 or 30 mg of biotin/d from calving through 70 d postpartum to
Lisa Helbling Chadwick et al.
Chromosoma, 118(4), 445-457 (2009-03-20)
Chromosomal replication results in the duplication not only of DNA sequence but also of the patterns of histone modification, DNA methylation, and nucleoprotein structure that constitute epigenetic information. Pericentromeric heterochromatin in human cells is characterized by unique patterns of histone
Tim Hebbrecht et al.
PloS one, 12(9), e0185076-e0185076 (2017-09-25)
Invasive cancer cells develop small actin-based protrusions called invadopodia, which perform a primordial role in metastasis and extracellular matrix remodelling. Neural Wiskott-Aldrich syndrome protein (N-WASp) is a scaffold protein which can directly bind to actin monomers and Arp2/3 and is
James Hulit et al.
Molecular and cellular biology, 24(17), 7598-7611 (2004-08-18)
Constitutive beta-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. Mice carrying Apc mutations in their germ line (ApcMin) develop intestinal adenomas. Here, the
Lifeng Tian et al.
Oncotarget, 5(17), 7303-7315 (2014-09-18)
In our prior publications we characterized a conserved acetylation motif (K(R)xxKK) of evolutionarily related nuclear receptors. Recent reports showed that peroxisome proliferator activated receptor gamma (PPARγ) deacetylation by SIRT1 is involved in delaying cellular senescence and maintaining the brown remodeling
Qi Peng et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6058-6068 (2009-10-30)
Regulation of T cell immunity by C5a has been suggested from recent studies. However, the underlying mechanisms, particularly the involved cells and biochemical basis, are not well defined. In this study, the direct modulation of dendritic cell (DC) activation and
Han-Gyu Kim et al.
Biochemical and biophysical research communications, 463(4), 632-637 (2015-06-06)
We investigated whether endogenous neuregulin 1 (NRG1) is released in a soluble form (called sNRG1) and upregulates expression of nicotinic acetylcholine receptor (nAChR) in autonomic major pelvic ganglion (MPG) neurons of adult rats. To elicit the release of sNRG1, either
Esther García et al.
Scientific reports, 6, 23590-23590 (2016-03-25)
Cancer cells form actin-rich degradative protrusions (invasive pseudopods and invadopodia), which allows their efficient dispersal during metastasis. Using biochemical and advanced imaging approaches, we demonstrate that the N-WASP-interactors WIP and WICH/WIRE play non-redundant roles in cancer cell invasion. WIP interacts
R Nairn et al.
Biochemistry, 20(16), 4739-4745 (1981-08-04)
The amino acid sequence of the cyanogen bromide (CNBr) fragment extending from position 24 to position 98 of the H-2Dd murine histocompatibility antigen has been determined by using radiochemical microsequencing techniques. This 75-residue fragment (CN-C) is one of two glycopeptides
Intaek Lee et al.
The Journal of biological chemistry, 279(51), 53007-53014 (2004-10-07)
Vacuolar H(+)-ATPase functions as a vacuolar proton pump and is responsible for acidification of intracellular compartments such as the endoplasmic reticulum, Golgi, lysosomes, and endosomes. Previous reports have demonstrated that a 16-kDa subunit (16K) of vacuolar H(+)-ATPase via one of
Min-Ji Choi et al.
Biochemical pharmacology, 144, 120-131 (2017-08-02)
Since microglia-associated neuroinflammation plays a pivotal role in the progression of neurodegenerative diseases, controlling microglial activation has been suggested as a potential therapeutic strategy. Here, we investigated the anti-inflammatory effects of galangin (3,5,7-trihydroxyflavone) in microglia and analyzed the underlying molecular
Faidon Magkos et al.
American journal of physiology. Endocrinology and metabolism, 292(6), E1568-E1574 (2007-02-01)
Our group (Magkos F, Wright DC, Patterson BW, Mohammed BS, Mittendorfer B, Am J Physiol Endocrinol Metab 290: E355-E362, 2006) has recently demonstrated that a single, prolonged bout of moderate-intensity cycling (2 h at 60% of peak oxygen consumption) in
Highly effective fluorescent and colorimetric sensors for pyrophosphate over H2PO4-in 100% aqueous solution.
Jang YJ, et al.
The Journal of Organic Chemistry, 70(23), 9603-9606 (2005)
R C Drugan et al.
Neuroscience, 253, 221-234 (2013-09-04)
Prior adverse experience alters behavioral responses to subsequent stressors. For example, exposure to a brief swim increases immobility in a subsequent swim test 24h later. In order to determine if qualitative differences (e.g. 19°C versus 25°C) in an initial stressor
Fang Fang et al.
Zhonghua nan ke xue = National journal of andrology, 18(9), 777-782 (2012-12-01)
To explore the correlation of low-dose radiation with endoplasmic reticulum stress and the activation of the PERK-CHOP signaling pathway in mouse testicular cells. Healthy Kunming mice were randomly assigned to time-effect (0, 3, 6, 12 and 24 h of irradiation
Rebecca Lewis Kelso et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 32(2), 177-183 (2006-01-31)
Perineural invasion (PNI) in cutaneous squamous cell carcinoma (CSCC) may portend a poor prognosis for patients. p75NGFR (nerve growth factor receptor) is part of a membrane receptor complex that binds nerve growth factor. Its use for detecting PNI in CSCC
Sathiyamoorthy Ezhaveni et al.
Journal of nanoscience and nanotechnology, 13(3), 1631-1638 (2013-06-13)
Nano-hydroxyapatite was synthesized by means of the hydrothermal treatment. The effects of nano-hydroxyapatite material on the behaviour of G2 liver cancer cells were explored. About 50% of cell viability was lost in nHAp material treated cells at 200 degrees C
Linda E Pelinka et al.
Shock (Augusta, Ga.), 19(3), 195-200 (2003-03-13)
This prospective clinical study was conducted to determine whether S 100 B is a reliable serum marker for traumatic brain injury (TBI) with and without multiple trauma. Fifty-five trauma patients (Injury Severity Score [ISS] > or = 24 and Glasgow
Ahad Hedayati et al.
Plant physiology and biochemistry : PPB, 155, 416-428 (2020-08-20)
Species of Hyoscyamus are rich sources of medicinally important tropane alkaloids, which have anticholinergic, antispasmodic and sedative effects and are competitive inhibitors of acetylcholine. The application of nanotechnology and nanomaterials for elicitation is rapidly expanding and recent research indicates that
Yoo Jung Yang et al.
European journal of pharmacology, 587(1-3), 57-64 (2008-05-07)
The effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells were investigated. Harman and norharman at a concentration of 20 microM and 100 microM showed 49.4% and 49.5% inhibition of dopamine content for 48 h
Gautam Singhvi et al.
Drug development and industrial pharmacy, 41(1), 105-108 (2013-10-30)
The aim of this study was to predict the in vivo plasma drug level of milnacipran (MIL) from in vitro dissolution data of immediate release (IR 50 mg and IR 100 mg) and matrix based controlled release (CR 100 mg) formulations. Plasma drug
Wierd P Zijlstra et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 30(5), 740-747 (2011-10-26)
Metal-on-metal hip arthroplasty is associated with elevated levels of cobalt and chromium ions. The effects of cobalt and chromium ions on cell number, activity, expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappa B ligand (RANKL) and oxidative
Sandra M Petralia et al.
Neuroendocrinology, 84(6), 405-414 (2007-03-27)
Progestin-facilitated lordosis of hamsters and rats is enhanced by activation of dopamine type 1 (D1) or GABAA/benzodiazepine receptor complexes (GBRs) in the ventral tegmental area (VTA) and these effects involve G-proteins and second messengers, such as adenosine 3',5'-monophosphate (cAMP). We
Aydan Yenisehirli et al.
European journal of pharmacology, 519(3), 259-266 (2005-08-30)
The effects of three specific H+/K+-ATPase inhibitors (omeprazole, lansoprazole and SCH 28080 (2-methyl-8-(phenylmethoxy)-imidazo[1,2-a] pyridine-3-acetonitrile)) were investigated on the mechanical and electrophysiological properties of rat atrium, in vitro. Omeprazole (100-300 microM), lansoprazole (100-300 microM) and SCH 28080 (10-100 microM) increased the
A G Hovanessian et al.
The Journal of biological chemistry, 263(10), 4945-4949 (1988-04-05)
The existence of distinct 69- and 100-kDa forms of 2-5A-synthetase in addition to the smaller (40 and 46 kDa) forms has recently been established. Using specific monoclonal antibodies we investigated the induction, synthesis, and activity of 69- and 100-kDa 2',5'-oligoadenylate
Liang Si et al.
Environmental toxicology and chemistry, 31(9), 2078-2084 (2012-06-21)
Nitrobenzene, although widely used in industry, is a highly toxic environmental pollutant. To evaluate the toxicity of nitrobenzene to tobacco seedlings, seedlings were exposed to varying concentrations of nitrobenzene (0-100 mg/L) for 24 h. The contents of reactive oxygen species
Chunlin Chen et al.
Taiwanese journal of obstetrics & gynecology, 59(3), 403-408 (2020-05-18)
Genistein obviously inhibits the migration and invasion of various tumor cells. However, its effects on cervical cancer cells have seldom been referred. We aimed to evaluate the effects of genistein on the proliferation, migration and invasion of cervical cancer HeLa
A T Rose et al.
The Journal of surgical research, 95(1), 19-22 (2000-12-20)
Vitamin E in the form of alpha-tocopherol succinate (ATS) has been shown to inhibit growth of several cancer cell lines in vitro, including pancreas, breast, and prostate. No data exist on the effect of ATS on gastric cancer cell viability.
Qing-Yu Zhang et al.
World journal of gastroenterology, 20(29), 10082-10093 (2014-08-12)
To investigate the effects of dihydromyricetin (DHM) on the migration and invasion of human hepatic cancer cells. The hepatoma cell lines SK-Hep-1 and MHCC97L were used in this study. The cells were cultured in RPIM-1640 medium supplemented with 10% fetal
M F Tsan et al.
American journal of respiratory cell and molecular biology, 19(1), 114-120 (1998-07-03)
Recent studies have shown that homozygous Mn superoxide dismutase (Sod2) gene-knockout mice (Sod2(-/-)) die shortly after birth with extensive myocardial injury, whereas heterozygous mutants (Sod2(+/-)) are phenotypically normal in room air. In the current study, we showed that Sod2(+/-) mice
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