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H1384
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显示 1-30 #N/A 142 条结果 关于 "H1384" 范围 论文
Dawei Yang et al.
Journal of translational medicine, 18(1), 243-243 (2020-06-20)
Lung cancer (LC) remains the deadliest form of cancer globally. While surgery remains the optimal treatment strategy for individuals with early-stage LC, what the metabolic consequences are of such surgical intervention remains uncertain. Negative enrichment-fluorescence in situ hybridization (NE-FISH) was
Sandra Milena Bernal Ulloa et al.
Zygote (Cambridge, England), 23(3), 367-377 (2014-01-16)
Cyclic adenosine monophosphate (cAMP) modulators have been used to avoid spontaneous oocyte maturation and concomitantly improve oocyte developmental competence. The current work evaluated the effects of the addition of cAMP modulators forskolin, 3-isobutyl-1-methylxanthine (IBMX) and cilostamide during in vitro maturation
Roseli F Gonçalves et al.
Reproduction, fertility, and development, 28(3), 293-301 (2014-09-18)
In the field of 'single cell analysis', many classical strategies like immunofluorescence and electron microscopy are the primary techniques of choice. However, these methodologies are time consuming and do not permit direct identification of specific molecular classes, such as lipids.
Hypotaurine protection on cell damage by singlet oxygen.
Pitari G
Taurine 4, 157-162 (2002)
Paul H Yancey et al.
Journal of experimental zoology. Part A, Ecological genetics and physiology, 311(6), 439-447 (2009-04-30)
Invertebrates at hydrothermal vents and cold seeps must cope with toxic H(2)S. One proposed protection mechanism involves taurine derivatives: At vents and seeps, many animals have high levels of hypotaurine and thiotaurine (a product of hypotaurine and HS), originally found
Kevin Guo et al.
Analytical chemistry, 81(10), 3919-3932 (2009-03-25)
We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass spectrometry (ESI-FTICR MS) detection. An isotope reagent, (13)C-dansyl chloride, can be
Ying Jin et al.
Neurochemistry international, 52(8), 1410-1415 (2008-04-18)
Homocysteine is an amino acid that is an important risk factor for several neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Increased homocysteine levels induce neuronal cell death in a variety of neuronal types. However, very few studies have probed
Luiz Fernando Feres et al.
Animal reproduction science, 193, 165-170 (2018-04-22)
The aim of the present study was to evaluate the likelihood of pregnancy of in vitro-produced (IVP) embryos from batches with distinct relative efficiencies. Data were retrospectively analyzed from 605 transvaginal ultrasonic-guided follicle aspiration sessions (OPU) followed by in vitro
Benjamin G Hoffstrom et al.
Nature chemical biology, 6(12), 900-906 (2010-11-17)
A hallmark of many neurodegenerative diseases is accumulation of misfolded proteins within neurons, leading to cellular dysfunction and cell death. Although several mechanisms have been proposed to link protein misfolding to cellular toxicity, the connection remains enigmatic. Here, we report
Xiaowei Shi et al.
Experimental cell research, 383(2), 111511-111511 (2019-07-31)
Clinical trials testing mesenchymal stem cell (MSC) as a cellular remedy for acute liver injury (ALI) are underway, but its underlying mechanism has not been thoroughly scrutinized. We highlight that the metabolomic profile of the liver-resident immune cells is significantly
Zoltán Ivics et al.
Nature protocols, 9(4), 810-827 (2014-03-15)
The pig has emerged as an important large animal model in biomedical and pharmaceutical research. We describe a protocol for high-efficiency germline transgenesis and sustained transgene expression in pigs by using the Sleeping Beauty (SB) transposon system. The protocol is
Chang Seon Ryu et al.
Biochemical pharmacology, 85(2), 197-206 (2012-11-06)
Tamoxifen (TAM) resistance is a main cause of therapeutic failure in breast cancers. Although methionine dependency is a phenotypic characteristic of tumor cells, the role of sulfur amino acid metabolism in chemotherapy resistance remains to be elucidated. This study compared
Dongxia Hou et al.
PloS one, 10(11), e0142442-e0142442 (2015-11-12)
Trophoblasts (TR) are specialized cells of the placenta and play an important role in embryo implantation. The in vitro culture of trophoblasts provided an important tool to investigate the mechanisms of implantation. In the present study, porcine trophoblast cells were
The Significance of hydrogen sulfide for Arabidopsis seed germination.
Baudouin E, et al.
Frontiers in Plant Science, 7, 930-930 (2016)
Theesit Juanpanich et al.
Animal science journal = Nihon chikusan Gakkaiho, 89(1), 42-51 (2017-09-01)
Generating techniques to enhance the success of blastomere separation is important for bovine economy, because it increases the number of transferable embryos. This study aimed to identify the optimum cryoprotectants for the vitrification of bovine embryos and the separation of
Min Zhang et al.
Scientific reports, 7(1), 11574-11574 (2017-09-16)
The developmental capacity of in vitro matured oocytes is inferior to that of the in vivo matured ones due to insufficient cytoplasmic maturation. Although great efforts were made to accomplish better cytoplasmic maturation by meiotic arrest maintenance (MAM) before in
Carlos Terriente-Palacios et al.
Journal of chromatography. A, 1589, 83-92 (2019-01-03)
A fast and reliable method for the simultaneous quantification of Taurine, Homotaurine, Hypotaurine and 19 amino acids in algae samples by Ultra-performance liquid chromatography coupled with diode array and tandem mass spectrometry (UHPLC-DAD-MS/MS) was optimized and validated. Target compounds were
Hui-Ting Yang et al.
The Journal of nutritional biochemistry, 20(2), 132-139 (2008-06-13)
The main purpose of this study was to evaluate changes in brain sulfur-containing amino acid (SCAA) metabolism to determine whether taurine intervened under continuous alcohol intake. We fed 80 male Sprague-Dawley rats 30% alcohol-containing water for 4 weeks. Eighty animals
Ying Hong et al.
Frontiers in pharmacology, 11, 833-833 (2020-06-27)
Most herbal polysaccharides possess multiple benefits against metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD) and obesity. However, the underlying mechanisms are largely unknown. Here, male C57BL/6J mice were fed with chow or high-fat diet (HFD) with or without
Ken-ichi Honjoh et al.
Amino acids, 38(4), 1173-1183 (2009-07-28)
Taurine is known to function as a protectant against various stresses in animal cells. In order to utilize taurine as a compatible solute for stress tolerance of yeast, isolation of cDNA clones for genes encoding enzymes involved in biosynthesis of
Moyu Taniguchi et al.
Journal of bioscience and bioengineering, 130(1), 63-70 (2020-04-09)
Japanese sake production involves three processes: rice koji fermentation, seed mash fermentation, and main mash fermentation. Traditional seed mash (kimoto) production utilizes natural lactic acid produced by lactic acid bacteria for pure cultures of only sake yeast, preventing the growth
Mikhail E Kandel et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(31), 18302-18309 (2020-07-22)
The ability to evaluate sperm at the microscopic level, at high-throughput, would be useful for assisted reproductive technologies (ARTs), as it can allow specific selection of sperm cells for in vitro fertilization (IVF). The tradeoff between intrinsic imaging and external
Protective effect of hypotaurine against oxidative stress-induced cytotoxicity in rat placental trophoblasts.
Nishimura T
Placenta, 36(6), 693-698 (2015)
Yongqiang Hu et al.
Scientific reports, 10(1), 10721-10721 (2020-07-03)
Improvement of the food value of rice straw is urgently required in rice crop growing areas to mitigate pollution caused by rice straw burning and enhance the supply of high-quality forages for ruminants. The aims of the present study were
Hui Chan Kwak et al.
Biochemical pharmacology, 96(3), 256-266 (2015-06-07)
The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocysteine and methionine, but not glutathione (GSH) were markedly
L B Ferré et al.
Reproduction in domestic animals = Zuchthygiene, 53(1), 26-33 (2017-09-12)
Straws of sex-sorted sperm are usually packaged at a low concentration (e.g., ~2.1 × 10
M M Mahadevan et al.
Fertility and sterility, 43(2), 263-267 (1985-02-01)
Removal of cumulus may increase the chance of fertilization in patients with sperm antibodies, may facilitate fertilization in vitro with a small number of spermatozoa, and is necessary for microsurgical injection procedures in vitro. The aim of this study was
Ultrastructural and immunohistochemical characterization of the bovine epiblast.
Vejlsted M, et al.
Biology of Reproduction, 72(3), 678-686 (2005)
Andrea Carenzo et al.
Cells, 9(8) (2020-08-07)
Oral premalignant lesions (OPLs) represent the most common oral precancerous conditions. One of the major challenges in this field is the identification of OPLs at higher risk for oral squamous cell cancer (OSCC) development, by discovering molecular pathways deregulated in
Sou Hyun Kim et al.
International journal of molecular sciences, 19(12) (2018-12-21)
Endoplasmic reticulum (ER) stress is involved in non-alcoholic fatty liver disease (NAFLD), but the relationship between oxidative stress, another well-known risk factor of NAFLD, and ER stress has yet to be elucidated. In this study, we treated mice with tunicamycin
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