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A Bouabidi et al.
Drug testing and analysis, 4(12), 1014-1027 (2012-05-23)
An innovative versatile strategy using Total Error has been proposed to decide about the method's validity that controls the risk of accepting an unsuitable assay together with the ability to predict the reliability of future results. This strategy is based
Elizabeth L Cordonier et al.
The Journal of nutritional biochemistry, 26(11), 1379-1384 (2015-08-26)
Holocarboxylase synthetase (HLCS) is the sole protein-biotin ligase in the human proteome. HLCS has key regulatory functions in intermediary metabolism, including fatty acid metabolism, and in gene repression through epigenetic mechanisms. The objective of this study was to identify food-borne
Alessio Innocenti et al.
Bioorganic & medicinal chemistry, 18(6), 2159-2164 (2010-02-27)
A series of phenolic acids and phenol natural products, such as p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, ferulic acid, gallic acid, syringic acid, quercetin, and ellagic acid, were investigated for their inhibitory effects against the metalloenzyme carbonic anhydrase (CA, EC
Shang-Gao Liao et al.
Phytochemical analysis : PCA, 24(1), 25-35 (2012-06-21)
A flavonoid-enriched extract (FEE) of Polygonum orientale was reported to show cardioprotective effect but only very few compounds were reported to contribute to the effect. Identification of compounds interacting with the target cardiac cell is important for the understanding of
Jian-Shuang Jiang et al.
Journal of Asian natural products research, 15(5), 427-432 (2013-04-23)
Two new glycoside compounds, named saffloquinoside C (1) and (-)-4-hydroxybenzoic acid-4-O-[6'-O-(2″-methylbutyryl)-β-D-glucopyranoside] (2), were isolated from the florets of Carthamus tinctorius. Their structures were elucidated by detailed spectroscopic means including UV, IR, HR-ESI-MS, 1D and 2D NMR, and CD data. Compound
Alessio Innocenti et al.
Bioorganic & medicinal chemistry, 16(15), 7424-7428 (2008-06-27)
Inhibition of 12 mammalian isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1), CA I-XIV, with a series of phenols was investigated. The inhibition profile by phenols of these CAs was distinct from those of the sulfonamides and their isosteres
Panfeng Yu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 959, 55-61 (2014-04-29)
This paper described a novel application of PEGylated magnetic carbon nanotubes as solid-phase extraction nanosorbents for the determination of puerarin in rat plasma by high performance liquid chromatography (HPLC). A solvothermal method was employed for the synthesis of monodisperse magnetites
Seth Dixon et al.
Journal of medicinal chemistry, 49(25), 7413-7426 (2006-12-08)
4-Amino-4-deoxychorismate synthase (ADCS) catalyzes the first step in the conversion of chorismate into p-aminobenzoate, which is incorporated into folic acid. We aim to discover compounds that inhibit ADCS and serve as leads for a new class of antimicrobial compounds. This
Pradeepraj Durairaj et al.
Enzyme and microbial technology, 70, 58-65 (2015-02-11)
FoCYP53A19, a novel cytochrome P450 capable of performing benzoate hydroxylation, was identified and characterized from the ascomycete Fusarium oxysporum f.sp. lycopersici. Comparative functional analysis of FoCYP53A19 with the heterologous and homologous cytochrome P450 reductases (CPR) such as Saccharomyces cerevisiae (ScCPR)
Wai Mun Loke et al.
The Journal of nutrition, 139(12), 2309-2314 (2009-10-09)
Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumption. Valid biomarkers of flavonoid intake may be useful for estimating exposure in a range of
H Shibusawa et al.
Endocrinologia japonica, 25(2), 185-189 (1978-04-01)
A radioimmunoassay for plasma 16alpha-hydroxypregnenolone has been developed using anti-16alpha-hydroxypregnenolone antiserum produced in rabbits immunized with 16 alpha-hydroxypregnenolone-3-succinate-bovine serum albumin. Radioimmunoassay data were processed and analysed for its validity using a four parameter logistic curve fitting routine with use of
Margreet R Olthof et al.
The Journal of nutrition, 133(6), 1806-1814 (2003-05-29)
Dietary phenols are antioxidants, and their consumption might contribute to the prevention of cardiovascular disease. Coffee and tea are major dietary sources of phenols. Dietary phenols are metabolized extensively in the body. Lack of quantitative data on their metabolites hinders
Jessica L di Gesso et al.
Molecular nutrition & food research, 59(6), 1143-1154 (2015-03-25)
Flavonoids are generally studied in vitro, in isolation, and as unmetabolized precursor structures. However, in the habitual diet, multiple flavonoids are consumed together and found present in the circulation as complex mixtures of metabolites. Using a unique study design, we
Chao-Bin Xue et al.
Bioorganic & medicinal chemistry, 15(5), 2006-2015 (2007-01-30)
Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-quinones. Inhibition of PO may provide a basis for novel environmentally friendly
Epicatechin, procyanidins, and phenolic microbial metabolites after cocoa intake in humans and rats.
Mireia Urpi-Sarda et al.
Analytical and bioanalytical chemistry, 394(6), 1545-1556 (2009-04-01)
Proanthocyanidins, flavonoids exhibiting cardiovascular protection, constitute a major fraction of the flavonoid ingested in the human diet. Although they are poorly absorbed, they are metabolized by the intestinal microbiota into various phenolic acids. An analytical method, based on an optimized
Ya-Jun Guo et al.
Food & function, 3(11), 1195-1205 (2012-08-08)
Edible macro-fungi are widely consumed as food sources for their flavors and culinary features. In order to explore the potential of macro-fungi as a natural resource of bioactive compounds, the antioxidant properties and polysaccharide contents of 49 edible macro-fungi from
M G Soni et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1335-1373 (2002-10-22)
Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through
Formation of novel polymeric films derived from 4-hydroxybenzoic acid
Ferreira L, et al.
Materials Chemistry and Physics, 129, 46-52 (2011)
Esterification of Carboxylic Acids with Trialkyloxonium Salts: Ethyl and Methyl 4?Acetoxybenzoates: Benzoic acid, 4?(acetyloxy)?, ethyl and methyl esters.
Douglas J, et al.
Organic Syntheses, 56, 59-59 (1977)
Chun-Mei Chen et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(9), 1368-1370 (2012-01-21)
To study the chemical constituents of Phryma leptostachya. The chemical constituents were isolated and purified by silica gel column, recrystallization and Pre-RP-HPLC and their structwes were elucidated by spectroscopic methods. Five compounds were obtained and identified as ursolic acid (1)
María José Romero-Silva et al.
PloS one, 8(2), e56038-e56038 (2013-02-19)
In this study, the gentisate and protocatechuate pathways in Burkholderia xenovorans LB400 were analyzed by genomic and functional approaches, and their role in 3-hydroxybenzoate (3-HBA) and 4-hydroxybenzoate (4-HBA) degradation was proposed. The LB400 genome possesses two identical mhbRTDHI gene clusters
Behrooz Darbani
International journal of molecular sciences, 22(11) (2021-06-03)
Gene clusters are becoming promising tools for gene identification. The study reveals the purposive genomic distribution of genes toward higher inheritance rates of intact metabolic pathways/phenotypes and, thereby, higher fitness. The co-localization of co-expressed, co-interacting, and functionally related genes was
Clive S Barker et al.
PloS one, 7(8), e44030-e44030 (2012-09-07)
The bacterial type III export apparatus is found in the flagellum and in the needle complex of some pathogenic Gram-negative bacteria. In the needle complex its function is to secrete effector proteins for infection into Eukaryotic cells. In the bacterial
San-Yong Wang et al.
Bioorganic & medicinal chemistry letters, 17(10), 2785-2788 (2007-03-28)
Twelve allenic aromatic ethers, some of them are natural products isolated from the mangrove fungus Xylaria sp. 2508 in the South China Sea, were synthesized. Their antitumor activities against KB and KBv200 cells were determined. All these compounds demonstrated cytotoxic
Xylose production from corn stover biomass by steam explosion combined with enzymatic digestibility.
Zhi-Hua Liu et al.
Bioresource technology, 193, 345-356 (2015-07-06)
A novel conversion process using steam explosion combined with enzymatic digestibility was exploited to increase sugar yield. Results showed that glucan and xylan recovery decreased with the increase of holding temperature and residence time in SE, respectively, while glucan and
A Cortéjade et al.
Talanta, 146, 694-706 (2015-12-24)
The aim of this study was to develop an analytical method and contribute to the assessment of the Exposome. Thus, a targeted analysis of a wide range of contaminants in contact with humans on daily routines in urine was developed.
Shutang Tan et al.
Cell reports, 33(9), 108463-108463 (2020-12-03)
The widely used non-steroidal anti-inflammatory drugs (NSAIDs) are derivatives of the phytohormone salicylic acid (SA). SA is well known to regulate plant immunity and development, whereas there have been few reports focusing on the effects of NSAIDs in plants. Our
Meral Turabik et al.
Environmental science and pollution research international, 21(14), 8387-8397 (2014-03-29)
The oxidative degradation of imidacloprid (ICP) has been carried out by electrochemical advanced oxidation processes (EAOPs), anodic oxidation, and electro-Fenton, in which hydroxyl radicals are generated electrocatalytically. Carbon-felt cathode and platinum or boron-doped diamond (BDD) anodes were used in electrolysis
Jih-Jung Chen et al.
Journal of natural products, 70(2), 202-205 (2007-02-24)
Four new dihydroagarofuranoid sesquiterpenes (1-4) and a new hydroxybenzylsalicylaldehyde, forkienin (5), together with nine known compounds have been isolated from the roots of Microtropis fokienensis. The structures of the new compounds were determined through analyses of physical data. Compounds 3
Giulia Caron et al.
Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in
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