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V K Il'in et al.
Vestnik Rossiiskoi akademii meditsinskikh nauk, (2)(2), 56-62 (2013-07-04)
Dysbiotic shifts in intestinal and pharyngeal microflora were studied in 22 normal volunteers in 9-, 14-, 105- and 520-d chamber experiments simulating some of the spaceflight factors. Two preparations were administered to prevent pharyngeal and intestinal dysbiosis: oral dry probiotic
Reply: To PMID 23347371.
Harsha Nagaraj et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(6), 377-377 (2013-07-03)
Taisuke Yoshimoto et al.
Biochemical and biophysical research communications, 455(3-4), 251-255 (2014-12-03)
Vinculin regulates a variety of cellular functions partly through stabilization of tumor suppressor PTEN. In order to study the role of vinculin in tumor progression other than PTEN stabilization, vinculin was knocked down in PTEN-deficient squamous cell carcinoma HSC-4 cells.
L Du et al.
Poultry science, 93(4), 989-1000 (2014-04-08)
Gelatins were extracted from mechanically separated turkey meat following 2 different approaches. The first method was based on a 2-stage batch extraction at 50 and 60°C, respectively, whereas the second method consisted of recovering gelatin from a collagen biomass obtained
Gary Mok et al.
International journal of radiation oncology, biology, physics, 90(2), 278-288 (2014-10-12)
Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity. A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation
Scapular dyskinesis is detrimental to shoulder tendon properties and joint mechanics in a rat model.
Katherine E Reuther et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(11), 1436-1443 (2014-07-30)
Shoulder tendon injuries are frequently seen in the presence of abnormal scapular motion, termed scapular dyskinesis. The cause and effect relationship between scapular dyskinesis and shoulder injury has not been directly defined. We developed and used an animal model to
Assaf Dotan et al.
Experimental eye research, 127, 190-195 (2014-08-12)
Our study demonstrates the effect of scleral cross-linking using riboflavin and ultraviolet-A radiation on the development of axial myopia in a rabbit model. Axial length of the eyeball was measured by A-scan ultrasound in 22 New Zealand white rabbits aged
Eric Y Chang et al.
AJR. American journal of roentgenology, 202(4), W376-W378 (2014-03-26)
The anisotropic fibrous structure of collagen can significantly affect MRI signal intensity. Use of this magic angle effect as a contrast mechanism has been previously termed "dipolar anisotropy fiber imaging." The goal of this pilot study was to use a
Liang Zhang et al.
Toxicology and applied pharmacology, 283(1), 50-56 (2015-01-15)
An abnormal high mobility group box 1 (HMGB1) activation and a decrease in receptor for advanced glycation end-product (RAGE) play a key role in the pathogenesis of pulmonary fibrosis. Protocatechuic aldehyde (PA) is a naturally occurring compound, which is extracted
Eugene J Sato et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(9), 1111-1116 (2014-05-20)
Rotator cuff tears can cause irreversible changes (e.g., fibrosis) to the structure and function of the injured muscle(s). Fibrosis leads to increased muscle stiffness resulting in increased tension at the rotator cuff repair site. This tension influences repairability and healing
Jianping Li et al.
Hypertension (Dallas, Tex. : 1979), 65(2), 328-334 (2014-11-19)
Estrogen regulation of myocardial chymase and chymase effects on cardiac remodeling are unknown. To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by inhibiting mast cell (MC) chymase release, transverse aortic constriction or sham surgery was performed
Alexander H Nave et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(7), 1446-1458 (2014-05-17)
Pulmonary vascular remodeling, the pathological hallmark of pulmonary arterial hypertension, is attributed to proliferation, apoptosis resistance, and migration of vascular cells. A role of dysregulated matrix cross-linking and stability as a pathogenic mechanism has received little attention. We aimed to
Fabiano Ribeiro Cirano et al.
The Journal of oral implantology, 40(6), 655-659 (2014-12-17)
This study analyzed the role of recombinant human bone morphogenetic protein 2 (rhBMP-2) and recombinant human bone morphogenetic protein 7 (rhBMP-7) in the adhesion and differentiation of rat osteoblast-like (osteo-1) cells cultured on chemically modified titanium surfaces. Osteo-1 cells were
Jun Shimizu et al.
Biochemical and biophysical research communications, 456(2), 626-630 (2014-12-17)
Oral supplementation with collagen hydrolysate (CH) has been shown to improve the condition of the skin in humans and experimental animals. Several hydroxyproline-containing oligo-peptides were previously detected in human peripheral blood after the ingestion of CH, and the two dipeptides
Daehwan Kim et al.
International journal of cancer, 135(11), 2547-2557 (2014-04-18)
Discoidin domain receptors (DDRs) are unusual receptor tyrosine kinases (RTKs) that are activated by fibrillar collagens instead of soluble growth factors. DDRs play an important role in various cellular functions and disease processes, including malignant progression. Compared to other RTKs
A B Shori et al.
Pakistan journal of biological sciences : PJBS, 15(24), 1160-1167 (2013-06-13)
There is an increasing demand of functional foods in developed countries. Yogurt plays an important role in the management of blood pressure. Several bioactive peptides isolated from Allium sativum or fish collagen have shown antihypertensive activity. Thus, in the present
Di Wu et al.
The Journal of biological chemistry, 289(49), 34033-34048 (2014-10-23)
We have reported previously that nonmuscle myosin II-interacting guanine nucleotide exchange factor (MyoGEF) plays an important role in the regulation of cell migration and cytokinesis. Like many other guanine nucleotide exchange factors (GEFs), MyoGEF contains a Dbl homology (DH) domain
Luigi Martino et al.
Nucleic acids research, 43(1), 645-660 (2014-12-10)
The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module. The La module comprises two domains, the La motif (LaM) and the RRM1, which together recognize
Jerome P Sullivan
Primary dental journal, 2(4), 49-55 (2014-01-29)
In the front of the mouth, the treatment of such a bony defect carries the risk of a poor aesthetic outcome. High patient expectations, combined with the difficulty of recreating a large mass of viable bone in which a dental
P Bainbridge
Journal of wound care, 22(8), 407-408 (2013-08-09)
Fibroblasts are critical in supporting normal wound healing, involved in key processes such as breaking down the fibrin clot, creating new extra cellular matrix (ECM) and collagen structures to support the other cells associated with effective wound healing, as well
Morgan D Silldorff et al.
The Journal of bone and joint surgery. American volume, 96(20), e175-e175 (2014-10-17)
Injury to the supraspinatus and infraspinatus tendons and the associated atrophic changes to the muscle remain a common clinical problem. Specifically, increased muscle stiffness has been implicated in failure of the repair and poor functional outcomes. We present a comparison
Self-organizing stem cells.
Natalie de Souza
Nature methods, 11(1), 31-31 (2014-02-14)
Amanda K Hare et al.
Biochemical and biophysical research communications, 456(1), 257-261 (2014-12-03)
The hyaluronan receptor for endocytosis (HARE), or Stabilin-2, is the mammalian endocytic clearance receptor for HA, heparin, advanced glycation end-products, acetylated and oxidized low-density lipoproteins and collagen N-terminal propeptides. This large 2551 amino acid receptor is encoded by a gene
Débora Lopes Salles Scheffel et al.
American journal of dentistry, 27(6), 330-334 (2015-02-25)
To evaluate the influence of the time elapsed between the application and photoactivation of Single Bond 2 (SB) on microtensile bond strength (μTBS) and collagen exposure at the adhesive interface produced in the presence of intrapulp pressure. Dentin occlusal surfaces
Bio-Emulation: biomimetically emulating nature utilizing a histoanatomic approach; visual synthesis.
Panaghiotis Bazos et al.
The international journal of esthetic dentistry, 9(3), 330-352 (2014-08-16)
A thorough understanding of the spatial distribution pertaining to the histo-anatomic coronal structures and dynamic light interaction of the natural dentition provides the dental team with the ultimate strategic advantage with regards to optical integration of the final restoration. The
Jonathan G Sham et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 799-804 (2014-03-15)
Hepatocellular carcinoma (HCC) is a devastating malignancy in which imperfect imaging plays a primary role in diagnosis. Glypican-3 (GPC3) is an HCC-specific cell surface proteoglycan overexpressed in most HCCs. This paper presents the use of (89)Zr-conjugated monoclonal antibody against GPC3
Serafim Tsitsilonis et al.
Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 20(2), 94-99 (2014-05-07)
The effect of anabolic androgenic steroids on tendons has not yet been fully elucidated. Aim of the present study was the evaluation of the impact of anabolic androgenic steroids on the biomechanical and histological characteristics of Achilles tendons. Twenty-four male
Invited commentary.
Liang Ge et al.
The Annals of thoracic surgery, 96(6), 2154-2154 (2013-12-04)
Big bubble DALK after CXL in keratoconic patients.
Alfonso Iovieno et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(12), 801-801 (2013-12-07)
Wei Li et al.
Biochemical pharmacology, 89(3), 370-385 (2014-04-08)
Preeclampsia is a complication of pregnancy manifested as maternal hypertension and often fetal growth restriction. Placental ischemia could be an initiating event, but the linking mechanisms leading to hypertension and growth restriction are unclear. We have shown an upregulation of
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