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Georgios Kotsakis et al.
The Journal of oral implantology, 40(6), 690-698 (2014-12-17)
It has been documented that after every extraction of one or more teeth, the alveolar bone of the respective region undergoes resorption and atrophy. Therefore, ridge preservation techniques are often employed after tooth extraction to limit this phenomenon. The benefits
Tomohiro Tanaka et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1370-1379 (2014-01-24)
Formation of proper neuromuscular connections is a process coordinated by both motoneuron-intrinsic and target-dependent programs. Under these programs, motoneurons innervate target muscles, escape programmed cell death during fetal development, and form neuromuscular junctions (NMJ). Although a number of studies have
Anastasios John Kanellopoulos
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(7), 504-505 (2013-07-04)
To report a novel application of collagen cross-linking (CXL) in refractive astigmatic enhancement of previously performed astigmatic keratotomy. A 28-year-old woman with prior history of bioptics correction of high myopic astigmatism with femtosecond laser-assisted astigmatic keratotomy followed by topography-guided LASIK
Solfrid J Sagstad et al.
American journal of physiology. Heart and circulatory physiology, 308(1), H29-H38 (2014-11-02)
Collagen and glycosaminoglycans (GAGs) constituting the ECM may limit the space available and thus exclude macromolecules from a fraction of the interstitial fluid (IF) phase. This exclusion phenomenon is of importance for transcapillary fluid and solute exchange. The purpose of
Eun Young Hwang et al.
Biochemical and biophysical research communications, 449(4), 425-431 (2014-05-27)
Periostin appears to be a unique extracellular protein secreted by fibroblasts that is upregulated following injury to the heart or changes in the environment. Periostin has the ability to associate with other critical extracellular matrix (ECM) regulators such as TGF-β
Atul Katarkar et al.
Biochemical and biophysical research communications, 456(3), 707-713 (2014-12-20)
Heat shock protein-47 (Hsp-47) is exclusive collagen specific molecular chaperone involved in the maturation, processing and secretion of procollagen. Hsp-47 is consistently upregulated in several fibrotic diseases. Till date there is no potential antifibrotic small molecule drug available and Hsp-47
Wei Chen et al.
Human pathology, 45(1), 160-165 (2013-12-11)
During progression from normal liver to cirrhosis, total collagen increases nearly 10-fold with an abnormal increase in fibril-forming collagen and other extracellular matrix molecules. However, little is known regarding the changes each collagen type undergoes during fibrogenesis. We assessed the
Morgan D Silldorff et al.
The Journal of bone and joint surgery. American volume, 96(20), e175-e175 (2014-10-17)
Injury to the supraspinatus and infraspinatus tendons and the associated atrophic changes to the muscle remain a common clinical problem. Specifically, increased muscle stiffness has been implicated in failure of the repair and poor functional outcomes. We present a comparison
Daehwan Kim et al.
International journal of cancer, 135(11), 2547-2557 (2014-04-18)
Discoidin domain receptors (DDRs) are unusual receptor tyrosine kinases (RTKs) that are activated by fibrillar collagens instead of soluble growth factors. DDRs play an important role in various cellular functions and disease processes, including malignant progression. Compared to other RTKs
Jun Shimizu et al.
Biochemical and biophysical research communications, 456(2), 626-630 (2014-12-17)
Oral supplementation with collagen hydrolysate (CH) has been shown to improve the condition of the skin in humans and experimental animals. Several hydroxyproline-containing oligo-peptides were previously detected in human peripheral blood after the ingestion of CH, and the two dipeptides
P Bainbridge
Journal of wound care, 22(8), 407-408 (2013-08-09)
Fibroblasts are critical in supporting normal wound healing, involved in key processes such as breaking down the fibrin clot, creating new extra cellular matrix (ECM) and collagen structures to support the other cells associated with effective wound healing, as well
Alexander H Nave et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(7), 1446-1458 (2014-05-17)
Pulmonary vascular remodeling, the pathological hallmark of pulmonary arterial hypertension, is attributed to proliferation, apoptosis resistance, and migration of vascular cells. A role of dysregulated matrix cross-linking and stability as a pathogenic mechanism has received little attention. We aimed to
Luigi Martino et al.
Nucleic acids research, 43(1), 645-660 (2014-12-10)
The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module. The La module comprises two domains, the La motif (LaM) and the RRM1, which together recognize
Di Wu et al.
The Journal of biological chemistry, 289(49), 34033-34048 (2014-10-23)
We have reported previously that nonmuscle myosin II-interacting guanine nucleotide exchange factor (MyoGEF) plays an important role in the regulation of cell migration and cytokinesis. Like many other guanine nucleotide exchange factors (GEFs), MyoGEF contains a Dbl homology (DH) domain
Fabiano Ribeiro Cirano et al.
The Journal of oral implantology, 40(6), 655-659 (2014-12-17)
This study analyzed the role of recombinant human bone morphogenetic protein 2 (rhBMP-2) and recombinant human bone morphogenetic protein 7 (rhBMP-7) in the adhesion and differentiation of rat osteoblast-like (osteo-1) cells cultured on chemically modified titanium surfaces. Osteo-1 cells were
A B Shori et al.
Pakistan journal of biological sciences : PJBS, 15(24), 1160-1167 (2013-06-13)
There is an increasing demand of functional foods in developed countries. Yogurt plays an important role in the management of blood pressure. Several bioactive peptides isolated from Allium sativum or fish collagen have shown antihypertensive activity. Thus, in the present
Jerome P Sullivan
Primary dental journal, 2(4), 49-55 (2014-01-29)
In the front of the mouth, the treatment of such a bony defect carries the risk of a poor aesthetic outcome. High patient expectations, combined with the difficulty of recreating a large mass of viable bone in which a dental
Amanda K Hare et al.
Biochemical and biophysical research communications, 456(1), 257-261 (2014-12-03)
The hyaluronan receptor for endocytosis (HARE), or Stabilin-2, is the mammalian endocytic clearance receptor for HA, heparin, advanced glycation end-products, acetylated and oxidized low-density lipoproteins and collagen N-terminal propeptides. This large 2551 amino acid receptor is encoded by a gene
Self-organizing stem cells.
Natalie de Souza
Nature methods, 11(1), 31-31 (2014-02-14)
Serafim Tsitsilonis et al.
Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 20(2), 94-99 (2014-05-07)
The effect of anabolic androgenic steroids on tendons has not yet been fully elucidated. Aim of the present study was the evaluation of the impact of anabolic androgenic steroids on the biomechanical and histological characteristics of Achilles tendons. Twenty-four male
Bio-Emulation: biomimetically emulating nature utilizing a histoanatomic approach; visual synthesis.
Panaghiotis Bazos et al.
The international journal of esthetic dentistry, 9(3), 330-352 (2014-08-16)
A thorough understanding of the spatial distribution pertaining to the histo-anatomic coronal structures and dynamic light interaction of the natural dentition provides the dental team with the ultimate strategic advantage with regards to optical integration of the final restoration. The
Jonathan G Sham et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 799-804 (2014-03-15)
Hepatocellular carcinoma (HCC) is a devastating malignancy in which imperfect imaging plays a primary role in diagnosis. Glypican-3 (GPC3) is an HCC-specific cell surface proteoglycan overexpressed in most HCCs. This paper presents the use of (89)Zr-conjugated monoclonal antibody against GPC3
Débora Lopes Salles Scheffel et al.
American journal of dentistry, 27(6), 330-334 (2015-02-25)
To evaluate the influence of the time elapsed between the application and photoactivation of Single Bond 2 (SB) on microtensile bond strength (μTBS) and collagen exposure at the adhesive interface produced in the presence of intrapulp pressure. Dentin occlusal surfaces
Invited commentary.
Liang Ge et al.
The Annals of thoracic surgery, 96(6), 2154-2154 (2013-12-04)
Shane Joseph McCrea
The Journal of oral implantology, 40(2), 189-195 (2014-05-02)
The dental literature reports frequently on both the success and survival of dental implants, whereby the focus remains on the biological response of hard and soft tissue to the implants. The predication and anticipation of adverse implant events can then
L Du et al.
Poultry science, 93(4), 989-1000 (2014-04-08)
Gelatins were extracted from mechanically separated turkey meat following 2 different approaches. The first method was based on a 2-stage batch extraction at 50 and 60°C, respectively, whereas the second method consisted of recovering gelatin from a collagen biomass obtained
Rahul Gawri et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(9), 1189-1197 (2014-05-28)
Presently, there are no established treatments to prevent, stop or even retard back pain arising from disc degeneration. Previous studies have shown that Link N can act as a growth factor and stimulate the synthesis of proteoglycans and collagens, in
Tim Lämmermann et al.
Nature, 498(7454), 371-375 (2013-05-28)
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined. Once outside the vessel
Ana K Bedran-Russo et al.
American journal of dentistry, 26(5), 244-248 (2014-02-01)
To assess in non-cavitated carious teeth the mechanical properties of dentin matrix by measuring its reduced modulus of elasticity and the effect of dentin biomodification strategies on three dentin matrix zones: caries-affected, apparently normal dentin below caries-affected zone and sound
Niraj Kumar Srivastava et al.
Indian journal of experimental biology, 52(7), 673-682 (2014-07-26)
Collagen-induced arthritis (CIA) was induced in female Wistar rats by intradermal injection of porcine immunization grade native collagen type II (Chondrex). Development and progression of CIA was monitored by studying histopathological, radiographical and biochemical features of arthritic manifestations in the
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