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Nuttawat Wangrangsimagul et al.
Applied microbiology and biotechnology, 93(2), 555-563 (2011-08-05)
Nowadays, majority of vanillin supplied to the world market is chemically synthesized from a petroleum-based raw material, raising a concern among the consumers regarding the product safety. In this study, an organic solvent-tolerant Brevibacillus agri 13 previously reported for a
T Atsumi et al.
Toxicology in vitro : an international journal published in association with BIBRA, 19(8), 1025-1033 (2005-06-21)
Eugenol (compound in , 4-allyl-2-methyoxyphenol) and isoeugenol (compound in , 4-propenyl-2-methoxyphenol), both used as a flavor agent in cosmetic and food products, have both prooxidant and antioxidant activities. Their adverse effects such as allergic and inflammatory reaction may be due
Long He et al.
Organic letters, 14(12), 3158-3161 (2012-06-08)
Highly enantio- and diastereoselective three-component inverse electron-demand aza-Diels-Alder reaction of aldehydes, anilines, and isoeugenol derivatives catalyzed by a chiral phosphoric acid catalyst are reported. A wide variety of 2,3,4-trisubstituted tetrahydroquinolines containing an aryl group at the 4-position were obtained in
Jakob Torp Madsen et al.
Cutaneous and ocular toxicology, 30(2), 116-123 (2011-01-05)
Attempts to improve formulation of topical products are a continuing process and the development of micro- and nanovesicular systems as well as polymeric microparticles has led to marketing of topical drugs and cosmetics using these technologies. Encapsulation of some well-known
A Luna et al.
British poultry science, 53(5), 631-639 (2013-01-04)
1. A study was conducted to evaluate whether feed supplementation with thymol or isoeugenol can alter Japanese quail growth rate and final body weight, the female onset of puberty, hen-day egg production and the physical and chemical characteristics of the
Batirtze Prats-Mateu et al.
Scientific reports, 8(1), 11804-11804 (2018-08-09)
Raman microscopy is a powerful imaging technique for biological materials providing information about chemistry in context with microstructure. A 532 nm laser is often used as excitation source, because high spatial resolution and signal intensity can be achieved. The latter can
Yuhe Liao et al.
Science (New York, N.Y.), 367(6484), 1385-1390 (2020-02-15)
The profitability and sustainability of future biorefineries are dependent on efficient feedstock use. Therefore, it is essential to valorize lignin when using wood. We have developed an integrated biorefinery that converts 78 weight % (wt %) of birch into xylochemicals.
Louise Arup Fischer et al.
Contact dermatitis, 64(6), 337-342 (2011-05-04)
Allergic contact dermatitis is triggered by chemicals in the environment. Primary prevention is aimed at minimizing the risk of induction, whereas secondary and tertiary prevention are aimed at reducing elicitation. To identify the elicitation doses that will elicit an allergic
Eva Kiorpelidou et al.
Chemical research in toxicology, 25(10), 2054-2056 (2012-09-06)
Cytokine release from dendritic cells in vitro is a useful marker to discriminate between sensitizing and irritant haptenic chemicals. Unfortunately, pro-haptens, which gain reactivity following metabolic/auto activation, yield negative results. To overcome this, we exposed human neutrophils and THP-1 cells
Fei Su et al.
Journal of bacteriology, 193(22), 6400-6401 (2011-11-01)
Bacillus pumilus S-1 is an efficient isoeugenol-utilizing producer of natural vanillin. The genome of B. pumilus S-1 contains the epoxide hydrolase and six candidate monooxygenases that make it possible to explore the mechanism involved in conversion of isoenguenol to vanillin
Annamaria London et al.
Natural product communications, 6(2), 235-236 (2011-03-24)
The root and leaf essential oils, present in trace amounts in Amsonia illustris Woods. (Apocynaceae), were isolated by steam distillation and their chemical constituents identified by GC-FID and GC-MS. More than 80% of the thirty volatile compounds in the leaf
Jessica Pérez-Outeiral et al.
Journal of chromatography. A, 1526, 82-92 (2017-10-24)
This work presents the development and validation of a multivariate method for quantitation of 6 potentially allergenic substances (PAS) related to fragrances by ultrasound-assisted emulsification microextraction coupled with HPLC-DAD and PARAFAC2 in the presence of other 18 PAS. The objective
Sandra Frahm et al.
Animals : an open access journal from MDPI, 10(7) (2020-07-24)
In this preliminary study, we compared changes in mechanical nociceptive thresholds (MNT) of calves and goat kids injected with clove oil or isoeugenol under the horn bud as a potential, more welfare-friendly alternative to hot-iron disbudding. Twenty male calves and
Morahem Ashengroph et al.
Applied biochemistry and biotechnology, 166(1), 1-12 (2011-10-13)
To screen strains of halotolerant or halophile bacteria which are able to convert isoeugenol to vanillin, 36 different strains of bacteria isolated from the salty environments in Iran were investigated. During growth on isoeugenol, a moderately halotolerant Gram-negative coccobacil showed
Sathya N Prasad et al.
Neurotoxicology, 33(5), 1254-1264 (2012-07-31)
Acrylamide (ACR) intoxication in its monomeric form leads to neuronal damage in both experimental animals and humans. Oxidative stress is one of the principle mechanisms related to the neurotoxicity of ACR exposure. Hence, the present study aimed to recapitulate the
Nur Ain Zamzuri et al.
Journal of the science of food and agriculture, 93(3), 429-438 (2012-12-05)
This review provides an overview of biovanillin production from agro wastes as an alternative food flavour. Biovanillin is one of the widely used flavour compounds in the foods, beverages and pharmaceutical industries. An alternative production approach for biovanillin as a
Morten Hyldgaard et al.
International journal of food microbiology, 215, 131-142 (2015-10-05)
Proliferation of microbial population on fresh poultry meat over time elicits spoilage when reaching unacceptable levels, during which process slime production, microorganism colony formation, negative organoleptic impact and meat structure change are observed. Spoilage organisms in raw meat, especially Gram-negative
Esra Fındık et al.
European journal of medicinal chemistry, 46(9), 4618-4624 (2011-08-17)
We are attempting to develop the novel phenolic synthetic antioxidants aimed at retarding the effects of free radicals and oxidants. The phenolic compounds (7-12) were synthesized by Friedel-Crafts alkylation of isoeugenol (1) and phenol derivatives (2-6) and their structures were
Elvira M Gaspar et al.
Journal of the science of food and agriculture, 99(4), 1668-1674 (2018-09-11)
Food irradiation is a widely used technique for improving the safety and shelf life of foods, including most spices. However, growing concerns by consumers about this technique require further investigation on the effects of radiation, both on the safety of
Ji-Young Ryu et al.
Bioscience, biotechnology, and biochemistry, 76(10), 1891-1896 (2012-10-11)
Vanillin is one of the most valuable compounds in the flavoring and fragrance industries, and many attempts to produce natural vanillin have been made in recent years. Isoeugenol monooxygenase (Iem) converts the phenylpropanoid compound isoeugenol to vanillin. In Pseudomonas nitroreducens
Charlotte Menné Bonefeld et al.
Contact dermatitis, 65(6), 336-342 (2011-07-20)
Perfumes are complex mixtures composed of many fragrance ingredients, many of which are known to be only weak allergens when tested individually. It is therefore surprising that fragrance contact allergy is one of the most common forms of contact allergy.
Yu-Ping Cao et al.
Immunopharmacology and immunotoxicology, 34(2), 196-204 (2011-07-05)
Many attempts have been made to develop in vitro sensitization tests that employ dendritic cells (DCs), DC-like cell lines or keratinocytes. The aim of the present investigation was to establish a co-culture of THP-1 cells and keratinocytes for evaluation of
Valentina Galbiati et al.
Archives of toxicology, 86(2), 239-248 (2011-10-05)
We previously demonstrated in the human promyelocytic cell line THP-1 that all allergens tested, with the exception of the prohapten isoeugenol, induced a dose-related release of interleukin-8 (IL-8). In the present study, we investigated whether this abnormal behavior was regulated
Daniel Melles et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 913-914, 106-112 (2013-01-05)
Skin sensitization is initiated by the modification of proteins located in the skin. After oxidative activation, eugenol and isoeugenol have the potential to modify skin proteins and therefore cause sensitization processes. Despite their known skin sensitizing properties, they are of
Aurélie Frankart et al.
Archives of dermatological research, 304(4), 289-303 (2012-01-25)
Models of reconstructed human epidermis (RHE) holding proliferating and fully differentiated cultured keratinocytes allow in vitro investigation of early molecular and cellular epidermal events during the complex response of keratinocytes at the onset of allergic contact dermatitis (ACD) or sensitization.
Gurpreet Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(8), 2689-2695 (2012-05-23)
Isoeugenol, a component of clover oil, possesses potent anti-inflammatory and antioxidant activity. In the present study, we investigated the effect on experimentally induced adjuvant arthritis in rats. Induction of arthritis in adjuvant exposed rats was confirmed by appearance of several
J Krupa et al.
The journal of physical chemistry. B, 116(36), 11148-11158 (2012-07-26)
In situ photochemical transformations of monomers of 2-methoxy-4-(prop-1-enyl)phenol (isoeugenol) and 2-methoxy-4-(prop-2-enyl)phenol (eugenol) isolated in low temperature matrices were induced by tunable UV laser light, and the progress of the reactions was followed by FTIR spectroscopy. Conformer-selective E ↔ Z geometrical
National Toxicology Program technical report series, (551)(551), 1-178 (2011-03-05)
Isoeugenol is one of several structurally similar phenylpropenoid compounds produced by plants. It has been extracted from calamus, savory, basil, ylang-ylang, clove, tuberose, jonquil, nutmeg, tobacco, sandalwood, dill seed, mace, gardenia, petunia, and other flowers. Isoeugenol can also be produced
Toshiki Furuya et al.
Chembiochem : a European journal of chemical biology, 15(15), 2248-2254 (2014-08-29)
Vanillin is one of the most widely used flavor compounds in the world as well as a promising versatile building block. The biotechnological production of vanillin from plant-derived ferulic acid has attracted much attention as a new alternative to chemical
Morgan Zielinski Goldberg et al.
Photochemistry and photobiology, 91(6), 1332-1339 (2015-08-14)
Lignocellulosic biomass can be converted to high-value phenolic compounds, such as food additives, antioxidants, fragrances and fine chemicals. We investigated photochemical and heterogeneous photocatalytic oxidation of two isomeric phenolic compounds from lignin, isoeugenol and eugenol, in several nonprotic solvents, for
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