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Martin Knaus et al.
Veterinary parasitology, 202(1-2), 64-68 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% w/v, (S)-methoprene 10% w/v, eprinomectin 0.4% w/v, and praziquantel 8.3% w/v (BROADLINE(®),(1) Merial) against larval and adult Aelurostrongylus abstrusus lungworms in cats was assessed in a controlled laboratory study. The
Laura Ruykys et al.
Journal of wildlife diseases, 49(2), 312-320 (2013-04-10)
We examined the clinical and cellular effects of sarcoptic mange on southern hairy-nosed wombats (SHNW, Lasiorhinus latifrons) and the effectiveness of a single dose of ivermectin as a treatment for captive and wild animals. Wambats were caught at three sites
Ivermectin (Sklice) topical lotion for head lice.
The Medical letter on drugs and therapeutics, 54(1396), 61-63 (2012-08-08)
Vitor Luís Tenório Mati et al.
The Journal of parasitology, 99(6), 1009-1018 (2013-08-06)
Abstract :  Seven cases of parasitism by Strongyloides cebus were identified in Lagothrix cana from Brazil. Aspects of the clinical presentation, treatment, pathology, and parasitic biology of these infections are described. Moderate to severe disease was observed, requiring hospitalization of
Henry O D Ejere et al.
The Cochrane database of systematic reviews, 8(8), CD002219-CD002219 (2012-08-17)
It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are uncertain and data on whether the
Dominique C Pichard et al.
Journal of the American Academy of Dermatology, 70(6), 1130-1134 (2014-05-17)
A 78-year-old Bulgarian woman presented to the National Institutes of Health (NIH) with a diagnosis of poorly differentiated metastatic carcinoma of unknown origin. The prior month she had been seen at a hospital in Bulgaria for weight loss and a
Shogo Furutani et al.
Molecular pharmacology, 86(6), 686-695 (2014-09-28)
Glutamate-gated chloride channels (GluCls) mediate fast inhibitory neurotransmission in invertebrate nervous systems. Insect GluCls show alternative splicing, and, to determine its impact on channel function and pharmacology, we isolated GluCl cDNAs from larvae of the silkworm (Bombyx mori). We show
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 45-48 (2014-04-08)
Infection with urinary capillarid bladder worms has been observed in cats worldwide. Although considered as generally causing no or little harm, infection with urinary capillarids may be associated with clinical disease which requires an appropriate treatment including the use of
Frank O Richards et al.
The American journal of tropical medicine and hygiene, 89(3), 578-587 (2013-08-14)
Lymphatic filariasis (LF) in rural southeastern Nigeria is transmitted mainly by Anopheles spp. mosquitoes. Potential coinfection with Loa loa in this area has prevented use of ivermectin in the mass drug administration (MDA) strategy for LF elimination because of potential
Christine Baker et al.
Veterinary parasitology, 202(1-2), 54-58 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v) and praziquantel 8.3% (w/v) (BROADLINE(®)) was tested against adult and immature stages of Ctenocephalides felis fleas in six studies. For that purpose, fleas
African Programme for Onchocerciasis Control: progress report, 2013-2014.
Releve epidemiologique hebdomadaire, 89(49), 551-560 (2014-12-09)
Topical ivermectin lotion for head lice.
Edith D Meacham
The New England journal of medicine, 368(10), 966-966 (2013-03-08)
River blindness eliminated in Colombia.
Sheila West et al.
Ophthalmic epidemiology, 20(5), 258-259 (2013-08-24)
Topical ivermectin lotion for head lice.
Olivier Chosidow et al.
The New England journal of medicine, 368(10), 968-968 (2013-03-09)
Yanping Liu et al.
Journal of bacteriology, 195(19), 4365-4372 (2013-07-31)
The role of a tetR transcriptional regulatory gene (SAV7471) in avermectin production in the Gram-positive soil bacterium Streptomyces avermitilis was investigated by gene deletion, complementation, and overexpression experiments. Gene deletion of the SAV7471 open reading frame resulted in avermectin overproduction.
Scientists celebrate successes, new tools in fight against human parasitic worms.
Bridget M Kuehn
JAMA, 310(1), 19-20 (2013-07-04)
Sklice (ivermectin) lotion for the treatment of head lice.
Noah Scheinfeld
Skinmed, 11(3), 171-172 (2013-08-13)
Mohamad Goldust et al.
Annals of parasitology, 59(1), 37-41 (2013-07-09)
Scabies is commonly treated with acaricides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of oral ivermectin vs. lindane lotion 1% for the treatment of scabies. Four hundred fourty patients with scabies were
African Programme for Onchocerciasis Control: meeting of National Onchocerciasis Task Forces, September 2013.
Releve epidemiologique hebdomadaire, 88(50), 533-544 (2013-12-26)
Carolina Flota-Bañuelos et al.
Revista de biologia tropical, 61(4), 1747-1758 (2014-01-18)
The spatial and temporal distribution of gastrointestinal nematodes of cattle has been little studied in Mexico. Previous studies have described periods of higher larval presence, vertical and horizontal migration in grasslands, and the frequency of adult nematodes; as well as
Niladri Mukherjee et al.
Experimental parasitology, 136, 41-58 (2013-11-28)
Lymphatic filariasis, a global cause of morbidity needs much more attention in developing potent therapeutics that can be effective against both microfilariae (mf) and adults. Efficient botanicals that can induce apoptosis of filarial parasites possibly can provide a direction towards
E Tielemans et al.
Veterinary parasitology, 202(1-2), 59-63 (2014-04-08)
Five controlled, blinded and randomized studies were conducted to examine the efficacy of a single topical application of a combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BROADLINE(®), Merial) against induced infestations with Ixodes ticks on cats. Three studies investigated the
Welber Daniel Zanetti Lopes et al.
Experimental parasitology, 135(1), 72-78 (2013-06-26)
The present study therefore assessed the deleterious effects of MLs (ivermectin, abamectin, doramectin and moxidectin) on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females that naturally detached from experimentally infested cattle in two experiments. The following reproductive parameters of
Joshua S Davis et al.
PLoS neglected tropical diseases, 7(9), e2387-e2387 (2013-09-27)
Crusted scabies, or hyperinfestation with Sarcoptes scabiei, occurs in people with an inadequate immune response to the mite. In recent decades, data have emerged suggesting that treatment of crusted scabies with oral ivermectin combined with topical agents leads to lower
James Whitehorn et al.
The Southeast Asian journal of tropical medicine and public health, 44(2), 179-181 (2013-05-23)
Ivermectin has been shown in in vitro studies to have insecticidal properties against Aedes aegypti adults. This study aimed to assess these properties in vivo. Aedes aegypti survival was not affected by acquiring a blood meal from humans both 5
Fernando Salvador et al.
The American journal of tropical medicine and hygiene, 90(5), 830-834 (2014-03-13)
Strongyloides stercoralis infection is being increasingly diagnosed out of endemic areas. The aim of this study is to evaluate the usefulness of S. stercoralis serology for the management of probable strongyloidiasis in patients presenting with eosinophilia. Overall, 147 patients were
Martin Knaus et al.
Veterinary parasitology, 202(1-2), 34-39 (2014-04-08)
The efficacy of a novel topical combination of fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v), and praziquantel 8.3% (w/v) (BROADLINE(®), Merial) was evaluated against adult and larval Toxocara cati in four controlled studies. All studies included experimentally infected
I Jana I Janssen et al.
Experimental parasitology, 134(2), 171-177 (2013-03-23)
P-glycoproteins (Pgps) are members of the ABC transporter superfamily and are involved in detoxification mechanisms of single- and multicellular organisms. Their importance for survival of organisms in the presence of harmful drug concentrations has been widely studied in cancer cells
Clinical safety of rapid sequential administration of moxidectin injection and oral derquantel-abamectin as a quarantine treatment for introduced sheep.
D J Bartram et al.
The Veterinary record, 172(16), 426-426 (2013-03-26)
Twice-yearly ivermectin for onchocerciasis: the time is now.
Moses Katabarwa et al.
The Lancet. Infectious diseases, 14(5), 373-374 (2014-04-25)
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