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M Sayın et al.
Neurologia i neurochirurgia polska, 47(4), 345-351 (2013-08-30)
Free radical production after spinal cord injury (SCI) plays an important role in secondary damage. The aim of this study was to investigate neuroprotective effects of the powerful antioxidant alpha-lipoic acid (ALA) in a spinal cord clip compression injury model.
Hirofumi Oyama et al.
Neurologia medico-chirurgica, 52(10), 769-773 (2012-10-26)
A 51-year-old female with a history of rheumatoid arthritis rapidly developed anterior neck pain and paresis in the left upper and lower extremities and right lower extremity, sensory disturbance in the left upper and lower extremities, and bladder and rectal
Ming Jiang et al.
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 27(5), 363-365 (2014-03-22)
To study the efficacy of early, enough methylprednisone combined with immunoglobulin in treatments of severe hand-foot-mouth disease. 568 patients of severe hand-foot-mouth disease involved were randomized into group A and group B. Patients of both groups all accepted symptomatic treatment
Reversal of severe hepatitis with infliximab in adult-onset Still's disease.
Bhavneet Singh et al.
The American journal of medicine, 126(2), e3-e4 (2013-01-22)
Successful treatment of anti-Caspr2 syndrome by interleukin 6 receptor blockade through tocilizumab.
Christos Krogias et al.
JAMA neurology, 70(8), 1056-1059 (2013-06-20)
A patient with a Caspr2 autoantibodies-associated syndrome had an unusual clinical triad and an excellent response to B-cell-anergizing therapy using the humanized monoclonal antibody tocilizumab directed against the interleukin 6 (IL-6) receptor. A 55-year-old man had an atypical clinical triad
Donald W Adams et al.
Foot (Edinburgh, Scotland), 22(3), 141-145 (2012-07-17)
Shoe contact dermatitis is common in both the pediatric and the adult populations. Severity of the reaction can vary greatly by patient. Health Care Professionals of all types should be familiar with shoe related dermatitis and aware of potential antigens
Fan Xu et al.
Pakistan journal of pharmaceutical sciences, 26(2), 261-265 (2013-03-05)
To assess the physical compatibility and chemical stability of doxofylline with methylprednisolone sodium succinate in 0.9% sodium chloride or 5% dextrose injection for intravenous infusion. Twenty mL doxofylline solution (0.74 mg/mL) and 1 mL methylprednisolone sodium succinate solution (0.15 mg/mL)
S Pescina et al.
International journal of pharmaceutics, 451(1-2), 12-17 (2013-05-01)
Trans-scleral iontophoresis, i.e. the application of small electric current to enhance drug transport across sclera is an option for non-invasive delivery of corticosteroids to the posterior segment of the eye. In this paper, in vitro trans-scleral iontophoresis of methylprednisolone hemisuccinate
Emerging therapies for acute traumatic spinal cord injury.
Jefferson R Wilson et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 185(6), 485-492 (2012-12-12)
Ji-Houn Kang et al.
American journal of veterinary research, 73(9), 1410-1417 (2012-08-29)
To determine whether parenteral l-alanyl-l-glutamine (Ala-Gln) administration modulated phagocytic responses of polymorphonuclear neutrophilic leukocytes (PMNs) from dogs undergoing high-dose methylprednisolone sodium succinate (MPSS) treatment. 15 healthy Beagles. Dogs were randomly assigned to 3 treatment groups (n = 5/group): 38-hour IV
Scleritis--Wegener's granulomatosis.
E Mitchel Opremcak
Insight (American Society of Ophthalmic Registered Nurses), 37(4), 13-13 (2012-12-22)
Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab.
Huai-Cheng Huang et al.
Annals of hematology, 92(7), 989-992 (2012-12-18)
Silvia Pescina et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 475-483 (2012-04-10)
Trans-scleral delivery is nowadays considered as a possible way to deliver drugs to the posterior segment of the eye. Despite the potentiality of this administration route, there is a lack of fundamental knowledge on the role of the numerous barriers
Susan Sun et al.
Cancer chemotherapy and pharmacology, 72(3), 509-513 (2013-07-19)
Fosaprepitant dimeglumine for injection is the water-soluble phosphorylated prodrug of the neurokinin-1 receptor antagonist aprepitant. Both agents are approved (in combination with a 5-HT3 antagonist and a corticosteroid) for prevention of chemotherapy-induced nausea and vomiting. Because fosaprepitant is likely to
A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.
Daniel Kiblboeck et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-08-29)
A patient experiencing anaphylaxis and urticaria, in some cases preceded by ingestion of red meat.
Phillip Lieberman et al.
The journal of allergy and clinical immunology. In practice, 1(1), 107-108 (2013-11-16)
Hoda Derakhshanian et al.
Canadian journal of physiology and pharmacology, 91(5), 380-385 (2013-05-10)
Glucocorticoid-induced osteoporosis (GIO) is the most common type of secondary osteoporosis. The aim of this study was to compare the efficacy of quercetin, a plant-derived flavonoid, with alendronate in the prevention of GIO. Fifty-six Sprague-Dawley rats were randomly distributed among
Seong Yong Park et al.
Interactive cardiovascular and thoracic surgery, 15(4), 639-643 (2012-06-30)
Respiratory failure from acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and pneumonia are the major cause of morbidity and mortality following an oesophagectomy for oesophageal cancer. This study was performed to investigate whether an intraoperative corticosteroid can attenuate
Lasse Murtomäki et al.
Journal of pharmaceutical sciences, 102(7), 2264-2272 (2013-05-15)
The affinity of a drug to a biological membrane can affect the distribution and the availability of the active compound to its target. Adsorption is usually determined with in vitro distribution studies based on partitioning of the drug between buffer
Claudia Druschel et al.
Spine, 38(11), E669-E677 (2013-03-01)
Written mail-out survey. To determine current practice in high-dose methylprednisolone succinate (MPSS) administration for treatment of acute spinal cord injury (SCI) in Germany. Reanalysis of the National Acute Spinal Cord Injury Studies (NASCIS) resulted in criticism of the use of
Severe atopic dermatitis accompanied by autoimmune retinopathy.
Takashi Nomura et al.
European journal of dermatology : EJD, 23(2), 263-264 (2013-04-17)
Lauren A Igneri et al.
Pharmacotherapy, 33(2), e14-e18 (2013-02-07)
Allergic hypersensitivity reactions are a rare adverse effect of corticosteroids. Previous reports have identified patients who developed symptoms of urticaria, dyspnea, hypotension, bronchospasm, and angioedema occurring within minutes to an hour after corticosteroid administration. A 35-year-old woman is described who
Kai-feng Wang et al.
Zhonghua wai ke za zhi [Chinese journal of surgery], 51(5), 426-431 (2013-08-21)
To investigate the effects and apoptosis of intrathecal injection of Methylprednisolone Sodium Succinate (MPss) for acute spinal cord injury (SCI) in New Zealand rabbits. Seventy-two healthy New Zealand rabbits were used for the procedure and were randomly divided into two
Sinem Civriz Bozdağ et al.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 48(3), 407-410 (2013-05-07)
Although chemotherapy combined with G-CSF is an effective method for hematopoietic stem cell mobilization, standard chemotherapy protocol leading to best stem cell yield is not defined. In our study, we aimed to assess the impact of chemotherapy choice on mobilization
Long-term selective IgE-mediated hypersensitivity to hydrocortisone sodium succinate.
G F Calogiuri et al.
Allergologia et immunopathologia, 41(3), 206-208 (2012-09-25)
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