CN
Search Within
m6204
应用筛选条件
关键词:'m6204'
显示 1-30 共 35 条结果 关于 "m6204" 范围 论文
Reactive polymers for modification of biologically active molecules and gene delivery vectors.
K Ulbrich et al.
Journal of controlled release : official journal of the Controlled Release Society, 116(2), e3-e5 (2007-08-28)
Cestmír Konák et al.
Langmuir : the ACS journal of surfaces and colloids, 24(14), 7092-7098 (2008-06-12)
Vesicles bearing either cationic (amino) groups or zwitterionic (amino acid) groups on the surface were coated with a reactive multivalent hydrophilic N-(2-hydroxypropyl)methacrylamide polymer (PHPMA) and its positively charged analogue (3 mol % quaternary ammonium groups), both having reactive thiazolidine-2-thione (TT)
Yan Zhou et al.
Biomaterials, 33(6), 1863-1872 (2011-12-06)
Improved treatments for prostate cancer are in great need to overcome lethal recurrence and metastasis. Targeting the tumorigenic cancer stem cells (CSCs) with self-renewal and differentiation capacity appears to be a promising strategy. Blockade of the hedgehog (Hh) signaling pathway
P Bojarová et al.
Journal of nanobiotechnology, 16(1), 73-73 (2018-09-22)
Galectin-3 (Gal-3) is a promising target in cancer therapy with a high therapeutic potential due to its abundant localization within the tumor tissue and its involvement in tumor development and proliferation. Potential clinical application of Gal-3-targeted inhibitors is often complicated
Taro Hase et al.
Urology, 60(3), 542-547 (2002-09-28)
To investigate the expression of peroxisome proliferator activator-receptor (PPAR)-alpha, beta, and gamma in human testicular cancer (TC) and normal testicular (NT) tissues, as well as the effects of the PPAR-gamma ligand. Recent studies have demonstrated that PPAR-gamma is expressed in
Homan Kang et al.
Scientific reports, 5, 10144-10144 (2015-05-29)
Recently, preparation and screening of compound libraries remain one of the most challenging tasks in drug discovery, biomarker detection, and biomolecular profiling processes. So far, several distinct encoding/decoding methods such as chemical encoding, graphical encoding, and optical encoding have been
Denis L Guerra et al.
Journal of hazardous materials, 183(1-3), 81-86 (2010-08-03)
The synthetic imogolite sample was used for organofunctionalization process with 2-mercaptothiazoline (MTZ). The compound 2-mercaptothiazoline was anchored onto imogolite surface by heterogeneous route. Due to the increment of basic centers attached to the pendant chains the dye adsorption capability of
R B Greenwald et al.
Bioconjugate chemistry, 7(6), 638-641 (1996-11-01)
A novel PEG linker that employs a thiazolidine-2-thione group has been synthesized. Kinetic studies done on this compound demonstrate a relatively long half-life compared to those of traditional succinimidyl linkers. This new PEG derivative reacts with proteins under mild conditions
Vladimír Subr et al.
Biomacromolecules, 7(1), 122-130 (2006-01-10)
N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymers (pHPMA) containing 4-nitrophenyl ester (ONp) or thiazolidine-2-thione (TT) reactive groups in side chains and telechelic/semitelechelic pHPMA with TT groups were designed as highly hydrophilic biocompatible polymers suitable for chemical coating of polyelectrolyte-based DNA-containing nanoparticles bearing amino groups
J C Thomes et al.
Japanese journal of pharmacology, 58(3), 201-207 (1992-03-01)
2-Thiazoline-2-thiol is an antithyroid agent that strongly reduces thyroid hormone levels. Synthesis of these hormones is catalyzed in vivo by thyroid peroxidase. The interaction of this drug with molecular iodine and its effect on peroxidase activity were investigated. Iodine and
Richard Laga et al.
Journal of biomaterials science. Polymer edition, 21(12), 1669-1685 (2010-06-12)
N-(2-Hydroxypropyl)methacrylamide (HPMA) co-polymers containing disulfide and carbonyl thiazolidine-2-thione (TT) reactive groups in their side-chains (pHPMA-TT) were used as reductively removable chemical modification of the surface of cowpea mosaic viruses (CPMV). CPMV was used in this study as a model particle
Henryk T Flakus et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 58(2), 225-237 (2002-01-26)
This paper deals with experimental studies on the polarization IR spectra of hydrogen bonds in 2-mercaptothiazoline and 2-mercapto-1-methylimidazole crystals. The crystal structure of 2-mercaptothiazoline was determined by X-ray diffraction. The polarization spectra of the two compounds were measured in the
Arash Nanbakhsh et al.
Blood, 123(23), 3585-3595 (2014-03-29)
Cytarabine (cytosine arabinoside) is one of the most effective drugs for the treatment of patients diagnosed with acute myeloid leukemia (AML). Despite its efficiency against AML cells, the emergence of drug resistance due to prolonged chemotherapy in most patients is
Lei Tao et al.
Organic & biomolecular chemistry, 7(17), 3481-3485 (2009-08-14)
A novel thiazolidine-2-thione functionalized chain transfer agent (CTA) was synthesized and used as a reversible addition-fragmentation chain transfer (RAFT) polymerization agent to prepare well-defined poly-N-(2-hydroxypropyl) methacrylamide (PHPMA). The polymer chains had pre-designed molecular weights, narrow polydispersities and were chain-end functionalized.
Eva Koziolová et al.
Nanoscale, 9(30), 10906-10918 (2017-07-22)
Here, we describe a novel polymer platform suitable for efficient diagnostics and potential theranostics based on
Chem. Abstr., 108, 37417r-37417r (1988)
Yoshinori Kadoma et al.
Molecules (Basel, Switzerland), 12(8), 1836-1844 (2007-10-26)
The reaction products in the presence of Lewis acid of isoeugenol (1) with ethanethiol, thiophenol, 2-mercaptothiazoline or 2-mercapto-1-methylimidazole (ISO-S1-ISO-S-4) were obtained. The radical-scavenging activity of these compounds was investigated using the induction period method for polymerization of methyl methacrylate (MMA)
R van Doorn et al.
Archives of toxicology, 47(1), 51-58 (1981-03-01)
A compound was isolated from the urine of workers exposed to carbon disulfide during the production of rayon. The compound was identified as 2-thiothiazolidine-4-carboxylic acid (TTCA) by GC/MS and NMR. A HPLC method for the quantitative determination of TTCA was
Newton L Dias Filho et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(11), 1309-1316 (2005-12-02)
A montmorillonite from Wyoming-USA was used to prepare an organo-clay complex, named 2-thiazoline-2-thiol-hexadecyltrimethylammonium-clay (TZT-HDTA-clay), for the purpose of the selective adsorption of the heavy metals ions and possible use as a chemically modified carbon paste electrode (CMCPE). Adsorption isotherms of
Y H Chen et al.
Chemosphere, 56(2), 133-140 (2004-05-04)
This study investigates the ozonation of 2-mercaptothiazoline (2-MT). The 2-MT is one of the important organic additives for the electroplating solution of the printed wiring board industry and has been widely used as a corrosion inhibitor in many industrial processes.
Petra Votavova et al.
Journal of biomedical nanotechnology, 11(9), 1662-1673 (2015-10-22)
Interleukin-2 (IL-2) possesses a strong stimulatory activity for activated T and NK cells and it is an attractive molecule for immunotherapy. Nevertheless, extremely short half-life and severe toxicities associated with high-dose IL-2 treatment are serious and limiting drawbacks. In order
Usama M Rabie et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 86, 252-255 (2011-12-02)
Interaction between thiazolidine-2-thione (T2T) as an electron donor and 2,3,5,6-tetrabromo-1,4-benzoquinone (p-bromanil, BRL) as a π-electron acceptor has been studied by using several spectral techniques, viz. UV/visible, IR, (1)H NMR and Mass spectra. A substitution reaction has been occurred after an
M Beyssen et al.
Pharmacology, 61(1), 22-30 (2000-07-15)
The influence of administration of tamoxifen (TAM) on thyroid metabolism was investigated. The potential action of TAM on iodine in the thyroid gland was evaluated by determination of the equilibrium constant of the charge transfer complex formed with molecular iodine
Libin Zhang et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 103, 36-46 (2017-03-03)
The aim of this study was to develop a new class of antibody-drug conjugates (ADCs) with the potential to not only enhance treatment efficacy but also improve tolerability for patients with B-cell lymphomas. Classic ADCs consist of monoclonal antibodies (mAbs)
M T Crimmins et al.
Organic letters, 2(6), 775-777 (2001-02-07)
[formula: see text] Asymmetric aldol additions using chlorotitanium enolates of thiazolidinethione propionates proceed with high diastereoselectivity for the "Evans" or "non-Evans" syn product depending on the nature and amount of the base used. With (-)-sparteine as the base, selectivities of
D Atzei et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 57A(5), 1073-1083 (2001-05-26)
Metal complexes of general formula M(ttz)2X2 (with M= Pd(II) or Pt(II); X = Cl or Br; ttz = 1,3-thiazolidine-2-thione) have been synthetized as crystalline compounds and studied by means of X-ray Photoelectron Spectroscopy (XPS). The chemical shift of core level
M L Beyssen et al.
The Journal of pharmacy and pharmacology, 51(6), 745-750 (1999-08-24)
Several compounds of pharmaceutical importance from a variety of chemical families, for example chlorpromazine and clomipramine, have been found to form charge-transfer complexes with iodine. We have investigated the influence of dietary iodine on thyroid-gland dysfunction induced by clomipramine, chlorpromazine
Usama M Rabie et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1411-1417 (2011-06-18)
Interaction of thiazolidine-2-thione (T2T) as an electron donor with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as an electron π-acceptor has been studied. Electronic absorption spectra of the system T2T-DDQ in several organic solvents of different polarities have been measured. A charge transfer (CT) complexation
Damián Pérez-Quintanilla et al.
Journal of hazardous materials, 134(1-3), 245-256 (2005-12-06)
Mesoporous silicas (SBA-15 and MCM-41) have been functionalized by two different methods. Using the heterogeneous route the silylating agent, 3-chloropropyltriethoxysilane, was initially immobilized onto the mesoporous silica surface to give the chlorinated mesoporous silica Cl-SBA-15 or Cl-MCM-41. In a second
Stud. Org. Chem., 28, 57-57 (1987)
1/2