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显示 1-16 共 16 条结果 关于 "MAB1910" 范围 论文
Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model.
Carlos, CP; Sonehara, NM; Oliani, SM; Burdmann, EA
Testing null
Audrey P Calzada et al.
Cell and tissue research, 350(2), 373-384 (2012-09-21)
The distribution of cochlin and its associated basement membrane proteins (collagen IV, collagen II, laminin-β2, and nidogen-1) were evaluated in the vestibular endorgans of subjects with Meniere's disease and compared with normal specimens. Cochlin mRNA expression in vestibular endorgans from
Elena Daniele et al.
BMJ open ophthalmology, 7(1) (2022-09-27)
Recent clinical studies have shown that the transplantation of functional retinal pigment epithelium (RPE) cells can prevent the onset of RPE degeneration in age-related macular degeneration. This study aimed to investigate the potential of human amniotic membrane (hAM) as a
Vincenzo Donadio et al.
Annals of neurology, 79(2), 306-316 (2015-11-26)
To characterize the expression in skin nerves of native (n-syn) and misfolded phosphorylated (p-syn) α-synucleins in pure autonomic failure (PAF) and idiopathic Parkinson disease (IPD). The specific aims were to (1) define the importance of n-syn and p-syn as disease
Matthew Riopel et al.
Islets, 6(4), e982949-e982949 (2014-11-27)
Development of the human pancreas is well-known to involve tightly controlled differentiation of pancreatic precursors to mature cells that express endocrine- or exocrine-specific protein products. However, details of human pancreatic development at the ultrastructural level are limited. The present study
Edward R Chu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 30(2-3), 191-201 (2014-02-13)
We have developed a tissue-based model of the human trabecular meshwork (TM) using viable postmortem corneoscleral donor tissue. Two-photon microscopy is used to optically section and image deep in the tissue to analyze cells and extracellular matrix (ECM) within the
Peter Trosan et al.
PloS one, 13(3), e0194820-e0194820 (2018-03-28)
The human amniotic membrane (HAM) is widely used for its wound healing effect in clinical practice, as a feeder for the cell cultivation, or a source of cells to be used in cell therapy. The aim of this study was
Daniel Öhlund et al.
BMC cancer, 13, 154-154 (2013-03-28)
Pancreatic cancer shows a highly aggressive and infiltrative growth pattern and is characterized by an abundant tumor stroma known to interact with the cancer cells, and to influence tumor growth and drug resistance. Cancer cells actively take part in the
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion.
Townley, AK; Schmidt, K; Hodgson, L; Stephens, DJ
Journal of Cell Science null
Jasmin I Maier et al.
Cell reports, 34(12), 108883-108883 (2021-03-25)
The integrity of the kidney filtration barrier essentially relies on the balanced interplay of podocytes and the glomerular basement membrane (GBM). Here, we show by analysis of in vitro and in vivo models that a loss of the podocyte-specific FERM-domain protein EPB41L5
Rocco Liguori et al.
PloS one, 12(7), e0180581-e0180581 (2017-07-04)
Fabry Disease (FD) is characterized by globotriaosylceramide-3 (Gb3) accumulation in several tissues and a small fibre neuropathy (SFN), however the underlying mechanisms are poorly known. This study aimed to: 1) ascertain the presence of Gb3 deposits in skin samples, by
Vincenzo Donadio et al.
Movement disorders : official journal of the Movement Disorder Society, 35(9), 1649-1657 (2020-06-20)
The differential diagnosis between multiple system atrophy parkinsonism type (MSA-P) and Parkinson's disease with orthostatic hypotension (PD+OH) is difficult because the 2 diseases have a similar clinical picture. The aim of this study is to distinguish MSA-P from PD+OH by
Gary Fisher et al.
Journal of cell communication and signaling, 12(1), 401-411 (2017-11-01)
In skin, the basement membrane at the dermal-epidermal junction (DEJ-BM) is an important structure that tightly binds the epidermis to the dermis, and acts as a permeability barrier that controls exchange of macromolecules. Repair of the DEJ-BM during wound healing
D Ohlund et al.
British journal of cancer, 101(1), 91-97 (2009-06-06)
Pancreas cancer is a dreaded disease with high mortality, despite progress in surgical and oncological treatments in recent years. The field is hampered by a lack of good prognostic and predictive tumour biomarkers to be used during follow-up of patients.
R L McMullen et al.
International journal of cosmetic science, 32(2), 143-154 (2010-04-24)
Image processing steps and analysis techniques were developed for the quantification of photomicrographs obtained from light and fluorescence microscopy. The substrates examined were either skin cell cultures, such as normal human keratinocytes (NHK) or fibroblasts, or ex vivo skin sections.
Elie Ngandu Mpoyi et al.
Biomaterials, 252, 120090-120090 (2020-05-16)
Basement membranes (BMs) are specialised extracellular matrices that provide structural support to tissues as well as influence cell behaviour and signalling. Mutations in COL4A1/COL4A2, a major BM component, cause a familial form of eye, kidney and cerebrovascular disease, including stroke
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