MS0100

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Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.

Joungil Choi et al.

The Journal of biological chemistry, 281(16), 10816-10824 (2006-03-07)

Mutations in DJ-1 cause an autosomal recessive, early onset familial form of Parkinson disease (PD). However, little is presently known about the role of DJ-1 in the more common sporadic form of PD and in other age-related neurodegenerative diseases, such

Proteomic screening of completely resected tumors in relation to survival in patients with stage I non-small cell lung cancer.

Fumihiro Oshita et al.

Oncology reports, 24(3), 637-645 (2010-07-29)

To investigate the early changes in protein function that induce micro-metastasis in early-stage non-small cell lung cancer, we conducted proteomic analysis of tissue that had been completely resected. We selected sixteen patients whose tumors were pathological stage I adenocarcinoma with

Insight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometry.

Yoshimi Kanie et al.

PloS one, 4(5), e5434-e5434 (2009-05-06)

A variety of N-glycans attached to protein are known to involve in many important biological functions. Endoplasmic reticulum (ER) and Golgi localized enzymes are responsible to this template-independent glycan synthesis resulting glycoforms at each asparagine residues. The regulation mechanism such

Mapping of disulfide bonds within the amino-terminal extracellular domain of the inhibitory glycine receptor.

Nicolas Vogel et al.

The Journal of biological chemistry, 284(52), 36128-36136 (2009-10-29)

The strychnine-sensitive glycine receptor (GlyR) is a ligand-gated chloride channel and a member of the superfamily of cysteine loop (Cys-loop) neurotransmitter receptors, which also comprises the nicotinic acetylcholine receptor (nAChR). Within the extracellular domain (ECD), the eponymous Cys-loop harbors two

New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly.

Roberta Cozzi et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26(5), 2008-2018 (2012-01-19)

Group B Streptococcus pili are covalently linked structures assembled via a sortase-catalyzed transpeptidation mechanism involving specific residues and motifs. A sequence element containing a conserved glutamic acid, called the E-box, has been described to be involved in pilus formation. Although

Identification of extensin protein associated with sugar beet pectin.

Alberto Nuñez et al.

Journal of agricultural and food chemistry, 57(22), 10951-10958 (2009-10-29)

Several studies have suggested that the emulsification properties associated with pectin obtained from sugar beet (Beta vulgaris) are due to the presence of a protein-pectin complex. Nevertheless, the identity of the protein has remained elusive. Pectin, extracted from sugar beet

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