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Koneni V Sashidhara et al.
European journal of medicinal chemistry, 50, 230-235 (2012-02-22)
Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol fraction (F4). Among the active galactolipids, 1 emerged as the
Dolors Company-Arumí et al.
Phytochemical analysis : PCA, 27(6), 326-335 (2016-10-22)
Protective plant lipophilic barriers such as suberin and cutin, with their associated waxes, are complex fatty acyl derived polyesters. Their precise chemical composition is valuable to understand the specific role of each compound to the physiological function of the barrier.
Mirka Macel et al.
Journal of chemical ecology, 46(11-12), 1082-1089 (2020-10-23)
The cuticular wax layer can be important for plant resistance to insects. Thrips (Frankliniella occidentalis) damage was assessed on 11 pepper accessions of Capsicum annuum and C. chinense in leaf disc and whole plant assays. Thrips damage differed among the
Angeles Fernández-Arche et al.
The Journal of nutritional biochemistry, 20(3), 155-162 (2008-06-17)
Pomace olive oil is a by-product of olive oil extraction that is traditionally produced and consumed in Spain. The nonglyceride matter of this oil is a good source of interesting minor compounds, like long-chain fatty alcohols, which are present free
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 27.
Andrew M Jones et al.
British journal of sports medicine, 45(15), 1246-1248 (2011-11-15)
Kyung Myung et al.
Journal of agricultural and food chemistry, 61(37), 8737-8742 (2013-08-24)
After foliar application, compounds that are not absorbed into leaves can be removed from the leaf surface by dipping or rinsing in dilutions of organic solvents in water. However, interactions between solvent mixtures and the epicuticular wax layer have received
Roberto Menéndez et al.
Archives of medical research, 36(2), 113-119 (2005-04-26)
Policosanol is a mixture of very-long-chain aliphatic alcohols purified from sugar cane wax with cholesterol-lowering effects, whose main component is octacosanol. Scarce data about the metabolism of octacosanol and the other fatty alcohols composing policosanol have been published. Human fibroblasts
Nizar Nasri et al.
Journal of agricultural and food chemistry, 55(6), 2251-2255 (2007-02-21)
Individual components of Pinus pinea L. oil unsaponifiable matter isolated from seven Mediterranean populations were identified and quantified. P. pinea oil unsaponifiable matter contained very high levels of phytosterols (>or=4298 mg kg-1 of total extracted lipids), of which beta-sitosterol was
Hyunjung Kim et al.
Journal of medicinal food, 6(4), 345-351 (2004-02-24)
This study evaluated the effects of octacosanol on running performance and related biochemical parameters in exercise-trained rats run to exhaustion on a treadmill. Male Sprague-Dawley rats were randomly assigned to one of three groups - sedentary control group (SC), exercise-trained
Wenfang Gao et al.
Journal of chromatographic science, 53(5), 811-815 (2014-08-26)
1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function. In this study, 1-octacosanol was extracted from Antarctic krill for the first time. Separation of 1-octacosanol was achieved using high-performance thin-layer chromatography (TLC) with a mobile phase consisting
Donporn Wongwaiwech et al.
Scientific reports, 10(1), 21007-21007 (2020-12-05)
The byproducts of rice bran oil processes are a good source of fat-soluble nutraceuticals, including γ-oryzanol, phytosterol, and policosanols. This study aimed to investigate the effects of green technology with low pressure as the subcritical fluid extraction with dimethyl ether
Xu Zhang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30(1), 38-41 (2007-06-02)
To study on the active components of Nardostachys chinensis Batal, the compounds were isolated and purified by chromatographic methods, with their structures identified by spectral analysis and comparison with published data. 9 compounds were obtained and their structures were identified
D Marrero Delange et al.
Journal of chromatography. B, Biomedical sciences and applications, 762(1), 43-49 (2001-10-09)
1-Octacosanol is the major component of policosanol, a new natural lowering-cholesterol agent. A sensitive solid-phase extraction with a Tenax GC capillary gas chromatography method for determining the proportion of this fatty alcohol in plasma after its denaturation with trichloroacetic acid
G Thippeswamy et al.
European journal of pharmacology, 588(2-3), 141-150 (2008-06-03)
Octacosanol is a long-chain aliphatic alcohol, which is the main component of policosanol used as a normolipidemic agent. It is known that angiogenesis is involved in tumor growth and metastasis. The present study identified octacosanol isolated from the plant Tinospora
Mahesh K Kaushik et al.
Scientific reports, 7(1), 8892-8892 (2017-08-23)
Octacosanol, a component of various food materials, possesses prominent biological activities and functions. It fights against cellular stress by increasing glutathione level and thus scavenging oxygen reactive species. However, its anti-stress activity and role in sleep induction remained elusive. We
Christopher P F Marinangeli et al.
The British journal of nutrition, 97(2), 381-388 (2007-02-15)
Policosanols (PC) exist as very-long-chain alcohols derived from sugarcane currently used in many countries as a cholesterol-lowering therapy. PC purity and relative percentage composition have been suggested as primary reasons why the original Cuban PC (OPC) supplements possess lipid-lowering efficacy.
Eduardo de Souza Esperança et al.
Food & function, 9(6), 3447-3455 (2018-06-08)
Some lipidic bioactives are largely reported to present hypocholesterolemic effects, for example, oleic acid, α-tocopherol, and octacosanol, found in rice-bran, olive, and sunflower oils. In contrast, some saturated and trans-unsaturated lipids found in animal fats or partially hydrogenated oils have
Tao Wang et al.
Acta pharmacologica Sinica, 31(7), 765-774 (2010-06-29)
To investigate the protective effects of octacosanol in 6-hydroxydopamine-induced Parkinsonian rats and find whether octacosanol has effects on pro nerve growth factor (pro-NGF), NGF and the downstream effector proteins. Behavioral tests, enzymatic assay, tyrosine hydroxylase immunohistochemistry, TUNEL and Western blot
S Wang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 24(10), 741-742 (2002-02-02)
The method was established for the determination of triacontanol and octacosanol in fenglasu and fenglasu capsules. The solvent was chloroform. The internal standard was hexatriacontanol. Using SIMPLCITY-1 capillary column, flame ionization detector was specified, injector temperature was 300 degrees C
Xiao-ying Yang et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 28(4), 652-653 (2008-05-23)
To evaluate the effect of octacostyl alcohol preparation on the motor function, blood free radical metabolism and cardiac endocrine function of rats. A rat model of exercise fatigue was used for this study. The rats were made to perform continuous
Ji-Eun Ra et al.
Food chemistry, 317, 126388-126388 (2020-02-23)
Policosanols is a health promoting aliphatic alcohol known as lipid-lowing agent. To enable maximising the functional properties of wheat, this research investigates the policosanol profiles and adenosine 5'-monophosphate-activated protein kinase (AMPK) activation potential of Korean wheat seedlings according to cultivars
Tai-sheng Lü et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 38(2), 113-115 (2003-06-05)
To study the chemical constituents of the stem of Cassia siamea. The compounds were isolated by chromatography on silica gel, and identified on the basis of spectral analysis. Five compounds were isolated and identified as: beta-sitosterol (I), sucrose (II), n-octacosanol
Ying Li et al.
mBio, 11(2) (2020-03-27)
The appressoria that are generated by the rice blast fungus Magnaporthe oryzae in response to surface cues are important for successful colonization. Previous work showed that regulators of G-protein signaling (RGS) and RGS-like proteins play critical roles in appressorium formation.
Surashree Sen Gupta et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 119, 201-214 (2017-06-27)
Octacosanol is a lesser known nutraceutical with the potential for treatment of several inflammatory diseases, high cholesterol, Parkinson's symptoms and tumour growth along with the capacity to improve athletic performance. But its lipophilicity and large structure inhibits extended solubility in
Giancarlo Cravotto et al.
Natural product research, 24(5), 428-439 (2010-03-23)
Lately, long-chain primary alcohols have been investigated in depth on account of their biological activities. In particular, 1-octacosanol (C(28)H(57)OH), the main component of policosanol, the hypolipidaemic fatty alcohol mixture obtained from sugar cane wax, has been the subject of a
Amira N Kassis et al.
Atherosclerosis, 194(1), 153-158 (2006-11-25)
Policosanol is a mixture of higher aliphatic alcohols shown to have beneficial effects on plasma lipid levels in animals and humans. Over 50 studies have reported significant reductions in plasma cholesterol using policosanol obtained from Cuban sugar cane (Dalmer, La
Sol Ji Choi et al.
Food chemistry, 204, 94-101 (2016-03-19)
Policosanol (PC) is a mixture of health promoting bioactive long-chain aliphatic alcohols. Here, we report that green tea (Camellia sinensis) leaves are the exceptionally rich plant-sources of PC. Young and tender leaves and old and turf leaves of C. sinensis
Arrigo F G Cicero et al.
Complementary therapies in medicine, 13(4), 273-278 (2005-12-13)
We planned to carry out a pilot study to evaluate the efficacy and safety as an antihypercholesterolemic agent of a brand dietary supplement made of Monascus purpureus titrated extract, octacosanols and niacin on 111 Caucasian patients with low cardiovascular disease
Dong Min Jung et al.
Journal of food science, 76(6), C891-C899 (2012-03-16)
Reportedly policosanols (PCs) have various beneficial functionalities on health. A gas chromatography-tandem mass spectrometry (GC-MS/MS) with a low limit of detection (LOD), and high specificity, recovery, and precision was successfully established for the PC analysis in vegetable oils. The LODs
Muthusamy Muthusamy et al.
Plants (Basel, Switzerland), 9(11) (2020-11-12)
The spectral quality and intensity of light, photoperiodism, and other environmental factors have profound impacts on the metabolic composition of light-dependent higher plants. Hence, we investigate the effects of fluorescent light (96 μmol m-2s-1) and white (100 μmol m-2s-1), blue
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