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Koneni V Sashidhara et al.
European journal of medicinal chemistry, 50, 230-235 (2012-02-22)
Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol fraction (F4). Among the active galactolipids, 1 emerged as the
Dolors Company-Arumí et al.
Phytochemical analysis : PCA, 27(6), 326-335 (2016-10-22)
Protective plant lipophilic barriers such as suberin and cutin, with their associated waxes, are complex fatty acyl derived polyesters. Their precise chemical composition is valuable to understand the specific role of each compound to the physiological function of the barrier.
Mirka Macel et al.
Journal of chemical ecology, 46(11-12), 1082-1089 (2020-10-23)
The cuticular wax layer can be important for plant resistance to insects. Thrips (Frankliniella occidentalis) damage was assessed on 11 pepper accessions of Capsicum annuum and C. chinense in leaf disc and whole plant assays. Thrips damage differed among the
Angeles Fernández-Arche et al.
The Journal of nutritional biochemistry, 20(3), 155-162 (2008-06-17)
Pomace olive oil is a by-product of olive oil extraction that is traditionally produced and consumed in Spain. The nonglyceride matter of this oil is a good source of interesting minor compounds, like long-chain fatty alcohols, which are present free
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 27.
Andrew M Jones et al.
British journal of sports medicine, 45(15), 1246-1248 (2011-11-15)
Kyung Myung et al.
Journal of agricultural and food chemistry, 61(37), 8737-8742 (2013-08-24)
After foliar application, compounds that are not absorbed into leaves can be removed from the leaf surface by dipping or rinsing in dilutions of organic solvents in water. However, interactions between solvent mixtures and the epicuticular wax layer have received
Roberto Menéndez et al.
Archives of medical research, 36(2), 113-119 (2005-04-26)
Policosanol is a mixture of very-long-chain aliphatic alcohols purified from sugar cane wax with cholesterol-lowering effects, whose main component is octacosanol. Scarce data about the metabolism of octacosanol and the other fatty alcohols composing policosanol have been published. Human fibroblasts
Nizar Nasri et al.
Journal of agricultural and food chemistry, 55(6), 2251-2255 (2007-02-21)
Individual components of Pinus pinea L. oil unsaponifiable matter isolated from seven Mediterranean populations were identified and quantified. P. pinea oil unsaponifiable matter contained very high levels of phytosterols (>or=4298 mg kg-1 of total extracted lipids), of which beta-sitosterol was
Hyunjung Kim et al.
Journal of medicinal food, 6(4), 345-351 (2004-02-24)
This study evaluated the effects of octacosanol on running performance and related biochemical parameters in exercise-trained rats run to exhaustion on a treadmill. Male Sprague-Dawley rats were randomly assigned to one of three groups - sedentary control group (SC), exercise-trained
Wenfang Gao et al.
Journal of chromatographic science, 53(5), 811-815 (2014-08-26)
1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function. In this study, 1-octacosanol was extracted from Antarctic krill for the first time. Separation of 1-octacosanol was achieved using high-performance thin-layer chromatography (TLC) with a mobile phase consisting
Donporn Wongwaiwech et al.
Scientific reports, 10(1), 21007-21007 (2020-12-05)
The byproducts of rice bran oil processes are a good source of fat-soluble nutraceuticals, including γ-oryzanol, phytosterol, and policosanols. This study aimed to investigate the effects of green technology with low pressure as the subcritical fluid extraction with dimethyl ether
Xu Zhang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30(1), 38-41 (2007-06-02)
To study on the active components of Nardostachys chinensis Batal, the compounds were isolated and purified by chromatographic methods, with their structures identified by spectral analysis and comparison with published data. 9 compounds were obtained and their structures were identified
D Marrero Delange et al.
Journal of chromatography. B, Biomedical sciences and applications, 762(1), 43-49 (2001-10-09)
1-Octacosanol is the major component of policosanol, a new natural lowering-cholesterol agent. A sensitive solid-phase extraction with a Tenax GC capillary gas chromatography method for determining the proportion of this fatty alcohol in plasma after its denaturation with trichloroacetic acid
G Thippeswamy et al.
European journal of pharmacology, 588(2-3), 141-150 (2008-06-03)
Octacosanol is a long-chain aliphatic alcohol, which is the main component of policosanol used as a normolipidemic agent. It is known that angiogenesis is involved in tumor growth and metastasis. The present study identified octacosanol isolated from the plant Tinospora
Mahesh K Kaushik et al.
Scientific reports, 7(1), 8892-8892 (2017-08-23)
Octacosanol, a component of various food materials, possesses prominent biological activities and functions. It fights against cellular stress by increasing glutathione level and thus scavenging oxygen reactive species. However, its anti-stress activity and role in sleep induction remained elusive. We
Christopher P F Marinangeli et al.
The British journal of nutrition, 97(2), 381-388 (2007-02-15)
Policosanols (PC) exist as very-long-chain alcohols derived from sugarcane currently used in many countries as a cholesterol-lowering therapy. PC purity and relative percentage composition have been suggested as primary reasons why the original Cuban PC (OPC) supplements possess lipid-lowering efficacy.
Eduardo de Souza Esperança et al.
Food & function, 9(6), 3447-3455 (2018-06-08)
Some lipidic bioactives are largely reported to present hypocholesterolemic effects, for example, oleic acid, α-tocopherol, and octacosanol, found in rice-bran, olive, and sunflower oils. In contrast, some saturated and trans-unsaturated lipids found in animal fats or partially hydrogenated oils have
Tao Wang et al.
Acta pharmacologica Sinica, 31(7), 765-774 (2010-06-29)
To investigate the protective effects of octacosanol in 6-hydroxydopamine-induced Parkinsonian rats and find whether octacosanol has effects on pro nerve growth factor (pro-NGF), NGF and the downstream effector proteins. Behavioral tests, enzymatic assay, tyrosine hydroxylase immunohistochemistry, TUNEL and Western blot
K Koch et al.
Planta, 223(2), 258-270 (2005-09-01)
In order to elucidate the self assembly process of plant epicuticular waxes, and the molecular arrangement within the crystals, re-crystallisation of wax platelets was studied on biological and non-biological surfaces. Wax platelets were extracted from the leaf blades of wheat
Daniela Haim et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(32), 4154-4158 (2009-11-26)
A method for the simultaneous determination of 1-octacosanol and 1-triacontanol and their main metabolites in rat plasma was developed. The procedure involved ethanolic NaOH saponification of the sample, acidification, liquid-liquid extraction, and derivatization of the analytes to its trimethylsilylether/ester, followed
Sylvia Keller et al.
Lipids, 43(2), 109-115 (2007-11-16)
To investigate octacosanol (OC) metabolism in humans and its influence on cholesterol metabolism, two studies were conducted. In the first study ten healthy women received daily 30 mg OC for a period of 4 weeks. Blood and feces samples were
Gregorio Martínez-Sánchez et al.
European journal of pharmacology, 691(1-3), 156-162 (2012-07-17)
Coronary artery disease (CAD) is the most common cause of sudden death, and death of people over 20 years of age. Because ozone therapy can activate the antioxidant system and improve blood circulation and oxygen delivery to tissue, the aim
Zhu Lian et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 26(1), 23-24 (2003-07-16)
Ten compounds were isolated from the dry fruit of Choerospondias axillaris (Roxb.) Burtt et Hill. Their structures were elucidated as dihydroquercetin(1), quercetin(2), protocatechuic acid(3), gallic acid(4), 3,3'-di-o-methylellagic acid(5), beta-sitosterol(6), daucosterol (7), stearic acid(8), triacontanoic acid(9), octacosanol(10) by IR, EI-MS and
Meng-Yuan Jiang et al.
Journal of agricultural and food chemistry, 68(30), 7850-7860 (2020-07-08)
Three new flavonoids, quercetin-3-O-6-[methyl-(S)-3-hydroxy-3-methylglutaroyl(1→6]-β-d-glucopyranoside (1), kaempferol-3-O-[methyl-(S)-3-hydroxy-3-methylglutaroyl(1→6)]-β-d-glucopyranoside (2), and quercetin-3-O-6-[(E)-4-methoxy-5-methylhexa-2,4-dienoatyl(1→6)]-β-d-glucopyranoside (3), and two new alkaloids, 5-dehydroxymethyl-pyrrolemarumine 4″-O-α-l-rhamnopyranoside (4) and N1-methyl-N2-((4-O-α-l-rhamnopyranoside)benzyl) oxalamide (5), together with 45 known compounds (6-50) were isolated from the leaves of Moringa oleifera Lam. Among those compounds, 1-octacosanol
Simonetta Oliaro-Bosso et al.
Lipids, 44(10), 907-916 (2009-09-19)
Octacosa-10,19-dien-1-ol is a newly synthesized long-chain alcohol, an unsaturated analogue of 1-octacosanol, the major component of policosanol, the purified natural mixture of different higher aliphatic alcohols obtained from sugarcane wax. Our efficient synthetic protocol (five steps with 50% overall yield)
Lingyao Kong et al.
Plant molecular biology, 96(1-2), 165-178 (2017-12-05)
Wheat TaCDK8 interacts with TaWIN1 to regulate very-long-chain aldehyde biosynthesis required for efficient germination of Blumeria graminis f.sp. tritici. Powdery mildew caused by Blumeria graminis f.sp. tritici (Bgt) is a devastating disease of common wheat (Triticum aestivum L.). Bgt infection
Ji-Eun Ra et al.
Food chemistry, 317, 126388-126388 (2020-02-23)
Policosanols is a health promoting aliphatic alcohol known as lipid-lowing agent. To enable maximising the functional properties of wheat, this research investigates the policosanol profiles and adenosine 5'-monophosphate-activated protein kinase (AMPK) activation potential of Korean wheat seedlings according to cultivars
Arrigo F G Cicero et al.
Complementary therapies in medicine, 13(4), 273-278 (2005-12-13)
We planned to carry out a pilot study to evaluate the efficacy and safety as an antihypercholesterolemic agent of a brand dietary supplement made of Monascus purpureus titrated extract, octacosanols and niacin on 111 Caucasian patients with low cardiovascular disease
Tianyi Guo et al.
Journal of agricultural and food chemistry, 65(18), 3647-3658 (2017-01-27)
Octacosanol has multiple biological functions. In this study, the anti-inflammatory effect and molecular mechanism of octacosanol were evaluated by using dextran sulfate sodium (DSS)-induced ulcerative colitis model in mice and lipopolysaccharide (LPS)-stimulated mouse macrophage RAW264.7 cells. The colitis mouse model
J M Calvo Romero et al.
Revista clinica espanola, 206(10), 504-506 (2006-11-30)
In this article we briefly review the evidence on the effect of different "natural" products on cholesterolemia. Plant stanols and sterols reduce cholesterol intestinal absorption and decrease total and LDL cholesterol by approximately 10%. Polycosanol is a mixture of saturated
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