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Xu Zhang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30(1), 38-41 (2007-06-02)
To study on the active components of Nardostachys chinensis Batal, the compounds were isolated and purified by chromatographic methods, with their structures identified by spectral analysis and comparison with published data. 9 compounds were obtained and their structures were identified
Donporn Wongwaiwech et al.
Scientific reports, 10(1), 21007-21007 (2020-12-05)
The byproducts of rice bran oil processes are a good source of fat-soluble nutraceuticals, including γ-oryzanol, phytosterol, and policosanols. This study aimed to investigate the effects of green technology with low pressure as the subcritical fluid extraction with dimethyl ether
G Thippeswamy et al.
European journal of pharmacology, 588(2-3), 141-150 (2008-06-03)
Octacosanol is a long-chain aliphatic alcohol, which is the main component of policosanol used as a normolipidemic agent. It is known that angiogenesis is involved in tumor growth and metastasis. The present study identified octacosanol isolated from the plant Tinospora
Christopher P F Marinangeli et al.
The British journal of nutrition, 97(2), 381-388 (2007-02-15)
Policosanols (PC) exist as very-long-chain alcohols derived from sugarcane currently used in many countries as a cholesterol-lowering therapy. PC purity and relative percentage composition have been suggested as primary reasons why the original Cuban PC (OPC) supplements possess lipid-lowering efficacy.
Eduardo de Souza Esperança et al.
Food & function, 9(6), 3447-3455 (2018-06-08)
Some lipidic bioactives are largely reported to present hypocholesterolemic effects, for example, oleic acid, α-tocopherol, and octacosanol, found in rice-bran, olive, and sunflower oils. In contrast, some saturated and trans-unsaturated lipids found in animal fats or partially hydrogenated oils have
Mahesh K Kaushik et al.
Scientific reports, 7(1), 8892-8892 (2017-08-23)
Octacosanol, a component of various food materials, possesses prominent biological activities and functions. It fights against cellular stress by increasing glutathione level and thus scavenging oxygen reactive species. However, its anti-stress activity and role in sleep induction remained elusive. We
D Marrero Delange et al.
Journal of chromatography. B, Biomedical sciences and applications, 762(1), 43-49 (2001-10-09)
1-Octacosanol is the major component of policosanol, a new natural lowering-cholesterol agent. A sensitive solid-phase extraction with a Tenax GC capillary gas chromatography method for determining the proportion of this fatty alcohol in plasma after its denaturation with trichloroacetic acid
Tao Wang et al.
Acta pharmacologica Sinica, 31(7), 765-774 (2010-06-29)
To investigate the protective effects of octacosanol in 6-hydroxydopamine-induced Parkinsonian rats and find whether octacosanol has effects on pro nerve growth factor (pro-NGF), NGF and the downstream effector proteins. Behavioral tests, enzymatic assay, tyrosine hydroxylase immunohistochemistry, TUNEL and Western blot
Hyunjung Kim et al.
Journal of medicinal food, 6(4), 345-351 (2004-02-24)
This study evaluated the effects of octacosanol on running performance and related biochemical parameters in exercise-trained rats run to exhaustion on a treadmill. Male Sprague-Dawley rats were randomly assigned to one of three groups - sedentary control group (SC), exercise-trained
Roberto Menéndez et al.
Archives of medical research, 36(2), 113-119 (2005-04-26)
Policosanol is a mixture of very-long-chain aliphatic alcohols purified from sugar cane wax with cholesterol-lowering effects, whose main component is octacosanol. Scarce data about the metabolism of octacosanol and the other fatty alcohols composing policosanol have been published. Human fibroblasts
Koneni V Sashidhara et al.
European journal of medicinal chemistry, 50, 230-235 (2012-02-22)
Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol fraction (F4). Among the active galactolipids, 1 emerged as the
Kyung Myung et al.
Journal of agricultural and food chemistry, 61(37), 8737-8742 (2013-08-24)
After foliar application, compounds that are not absorbed into leaves can be removed from the leaf surface by dipping or rinsing in dilutions of organic solvents in water. However, interactions between solvent mixtures and the epicuticular wax layer have received
Dolors Company-Arumí et al.
Phytochemical analysis : PCA, 27(6), 326-335 (2016-10-22)
Protective plant lipophilic barriers such as suberin and cutin, with their associated waxes, are complex fatty acyl derived polyesters. Their precise chemical composition is valuable to understand the specific role of each compound to the physiological function of the barrier.
Angeles Fernández-Arche et al.
The Journal of nutritional biochemistry, 20(3), 155-162 (2008-06-17)
Pomace olive oil is a by-product of olive oil extraction that is traditionally produced and consumed in Spain. The nonglyceride matter of this oil is a good source of interesting minor compounds, like long-chain fatty alcohols, which are present free
Wenfang Gao et al.
Journal of chromatographic science, 53(5), 811-815 (2014-08-26)
1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function. In this study, 1-octacosanol was extracted from Antarctic krill for the first time. Separation of 1-octacosanol was achieved using high-performance thin-layer chromatography (TLC) with a mobile phase consisting
Nizar Nasri et al.
Journal of agricultural and food chemistry, 55(6), 2251-2255 (2007-02-21)
Individual components of Pinus pinea L. oil unsaponifiable matter isolated from seven Mediterranean populations were identified and quantified. P. pinea oil unsaponifiable matter contained very high levels of phytosterols (>or=4298 mg kg-1 of total extracted lipids), of which beta-sitosterol was
Mirka Macel et al.
Journal of chemical ecology, 46(11-12), 1082-1089 (2020-10-23)
The cuticular wax layer can be important for plant resistance to insects. Thrips (Frankliniella occidentalis) damage was assessed on 11 pepper accessions of Capsicum annuum and C. chinense in leaf disc and whole plant assays. Thrips damage differed among the
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 27.
Andrew M Jones et al.
British journal of sports medicine, 45(15), 1246-1248 (2011-11-15)
Tai-sheng Lü et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 38(2), 113-115 (2003-06-05)
To study the chemical constituents of the stem of Cassia siamea. The compounds were isolated by chromatography on silica gel, and identified on the basis of spectral analysis. Five compounds were isolated and identified as: beta-sitosterol (I), sucrose (II), n-octacosanol
Xiao-ying Yang et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 28(4), 652-653 (2008-05-23)
To evaluate the effect of octacostyl alcohol preparation on the motor function, blood free radical metabolism and cardiac endocrine function of rats. A rat model of exercise fatigue was used for this study. The rats were made to perform continuous
S Wang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 24(10), 741-742 (2002-02-02)
The method was established for the determination of triacontanol and octacosanol in fenglasu and fenglasu capsules. The solvent was chloroform. The internal standard was hexatriacontanol. Using SIMPLCITY-1 capillary column, flame ionization detector was specified, injector temperature was 300 degrees C
Giancarlo Cravotto et al.
Natural product research, 24(5), 428-439 (2010-03-23)
Lately, long-chain primary alcohols have been investigated in depth on account of their biological activities. In particular, 1-octacosanol (C(28)H(57)OH), the main component of policosanol, the hypolipidaemic fatty alcohol mixture obtained from sugar cane wax, has been the subject of a
Amira N Kassis et al.
Atherosclerosis, 194(1), 153-158 (2006-11-25)
Policosanol is a mixture of higher aliphatic alcohols shown to have beneficial effects on plasma lipid levels in animals and humans. Over 50 studies have reported significant reductions in plasma cholesterol using policosanol obtained from Cuban sugar cane (Dalmer, La
Ying Li et al.
mBio, 11(2) (2020-03-27)
The appressoria that are generated by the rice blast fungus Magnaporthe oryzae in response to surface cues are important for successful colonization. Previous work showed that regulators of G-protein signaling (RGS) and RGS-like proteins play critical roles in appressorium formation.
Surashree Sen Gupta et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 119, 201-214 (2017-06-27)
Octacosanol is a lesser known nutraceutical with the potential for treatment of several inflammatory diseases, high cholesterol, Parkinson's symptoms and tumour growth along with the capacity to improve athletic performance. But its lipophilicity and large structure inhibits extended solubility in
Tianyi Guo et al.
Journal of agricultural and food chemistry, 65(18), 3647-3658 (2017-01-27)
Octacosanol has multiple biological functions. In this study, the anti-inflammatory effect and molecular mechanism of octacosanol were evaluated by using dextran sulfate sodium (DSS)-induced ulcerative colitis model in mice and lipopolysaccharide (LPS)-stimulated mouse macrophage RAW264.7 cells. The colitis mouse model
Meng-Yuan Jiang et al.
Journal of agricultural and food chemistry, 68(30), 7850-7860 (2020-07-08)
Three new flavonoids, quercetin-3-O-6-[methyl-(S)-3-hydroxy-3-methylglutaroyl(1→6]-β-d-glucopyranoside (1), kaempferol-3-O-[methyl-(S)-3-hydroxy-3-methylglutaroyl(1→6)]-β-d-glucopyranoside (2), and quercetin-3-O-6-[(E)-4-methoxy-5-methylhexa-2,4-dienoatyl(1→6)]-β-d-glucopyranoside (3), and two new alkaloids, 5-dehydroxymethyl-pyrrolemarumine 4″-O-α-l-rhamnopyranoside (4) and N1-methyl-N2-((4-O-α-l-rhamnopyranoside)benzyl) oxalamide (5), together with 45 known compounds (6-50) were isolated from the leaves of Moringa oleifera Lam. Among those compounds, 1-octacosanol
Simonetta Oliaro-Bosso et al.
Lipids, 44(10), 907-916 (2009-09-19)
Octacosa-10,19-dien-1-ol is a newly synthesized long-chain alcohol, an unsaturated analogue of 1-octacosanol, the major component of policosanol, the purified natural mixture of different higher aliphatic alcohols obtained from sugarcane wax. Our efficient synthetic protocol (five steps with 50% overall yield)
Lingyao Kong et al.
Plant molecular biology, 96(1-2), 165-178 (2017-12-05)
Wheat TaCDK8 interacts with TaWIN1 to regulate very-long-chain aldehyde biosynthesis required for efficient germination of Blumeria graminis f.sp. tritici. Powdery mildew caused by Blumeria graminis f.sp. tritici (Bgt) is a devastating disease of common wheat (Triticum aestivum L.). Bgt infection
Daniela Haim et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(32), 4154-4158 (2009-11-26)
A method for the simultaneous determination of 1-octacosanol and 1-triacontanol and their main metabolites in rat plasma was developed. The procedure involved ethanolic NaOH saponification of the sample, acidification, liquid-liquid extraction, and derivatization of the analytes to its trimethylsilylether/ester, followed
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