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关键词:'P-076'
显示 1-30 共 147 条结果 关于 "P-076" 范围 论文
In reply: Propofol and additives in studies evaluating inflammatory responses.
Gianluca Bertolizio et al.
Journal of pediatric hematology/oncology, 37(1), 73-74 (2013-12-07)
ALSUntangled No. 22: Propofol.
Amyotrophic lateral sclerosis & frontotemporal degeneration, 14(7-8), 640-642 (2013-08-27)
Mana Saraghi et al.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 34(4), 252-258 (2013-07-31)
With little room for error and recent reports of abuse and deaths, propofol, a commonly used general anesthetic induction agent, has provoked considerable concern and has stirred debate regarding its classification and how care should be rendered. The drug, when
S Bache et al.
British journal of anaesthesia, 110(5), 741-746 (2012-12-22)
Over a 5 yr period, we have encountered three patients in whom remifentanil appeared to have no clinical effect during general anaesthesia (GA). We describe seven anaesthetics in these three patients. We reviewed the literature on this subject. A simple
No difference in blood loss during endoscopic sinus surgery with total intravenous anesthesia?
Luca La Colla et al.
JAMA otolaryngology-- head & neck surgery, 139(10), 1077-1077 (2013-10-19)
Improving safety during sedation by nonanesthesiologists: do we lead or follow?
Carl Rosow
Anesthesia and analgesia, 119(1), 7-8 (2014-06-20)
Akira Asai et al.
Internal medicine (Tokyo, Japan), 52(7), 761-765 (2013-04-03)
A 75-year-old woman developed depression in 2010 and was treated with oral medications at our Department of Psychiatry. Since she showed no tendency toward improvement, she underwent modified electroconvulsive therapy (mECT). Later, she developed severe liver injury that was presumably
Sevoflurane--compared with propofol-based anesthesia reduces the need for inotropic support in patients undergoing abdominal aortic aneurysm repair: evidence of cardioprotection by volatile anesthetics in noncardiac surgery.
Michael Zaugg et al.
Anesthesiology, 120(5), 1289-1290 (2014-04-24)
C Creeley et al.
British journal of anaesthesia, 110 Suppl 1, i29-i38 (2013-06-05)
Exposure of the fetal or neonatal non-human primate (NHP) brain to isoflurane or ketamine for 5 h causes widespread apoptotic degeneration of neurones, and exposure to isoflurane also causes apoptotic degeneration of oligodendrocytes (OLs). The present study explored the apoptogenic
Lisa Rancan et al.
Transplantation, 98(11), 1151-1157 (2014-10-01)
Transplants cause ischemia-reperfusion (IR) injury that can affect distant organs. Liver is particularly sensitive to IR injury. The present randomized experimental study was designed to investigate a possible protective effect of sevoflurane against liver inflammatory response to lung IR in
Emergency medicine team of the year.
Vanessa Sibbald
BMJ (Clinical research ed.), 348, g2861-g2861 (2014-04-25)
The effective effect-site propofol concentration for induction in morbidly obese patients using total body weight with a new pharmacokinetic model.
Natalia F de la Fuente et al.
Anesthesia and analgesia, 117(1), 283-284 (2013-06-22)
Borna Ghosh et al.
The Journal of biological chemistry, 288(24), 17420-17431 (2013-05-04)
General anesthetics exert many of their CNS actions by binding to and modulating membrane-embedded pentameric ligand-gated ion channels (pLGICs). The structural mechanisms underlying how anesthetics modulate pLGIC function remain largely unknown. GLIC, a prokaryotic pLGIC homologue, is inhibited by general
Chihiro Iwata et al.
Anesthesia and analgesia, 118(1), 125-131 (2013-11-20)
It is thought that the gravitational environment of space exploration alters the effects of anesthetics; however, no evidence has as yet been reported. In the present study, we sought to provide direct evidence showing that hypergravity exposure for 14 days
Anesthesia and increased hypercarbic drive impair the coordination between breathing and swallowing.
Olivia M D'Angelo et al.
Anesthesiology, 121(6), 1175-1183 (2014-10-03)
Coordination between breathing and swallowing helps prevent aspiration of foreign material into the respiratory tract. The authors examined the effects of anesthesia and hypercapnia on swallowing-breathing coordination. In a randomized controlled crossover study, general anesthesia with propofol or sevoflurane was
Primum non nocere or how to resolve drug-induced respiratory depression.
Albert Dahan et al.
Anesthesiology, 118(6), 1261-1263 (2013-05-24)
UnCheol Lee et al.
Anesthesiology, 118(6), 1264-1275 (2013-05-23)
Directional connectivity from anterior to posterior brain regions (or "feedback" connectivity) has been shown to be inhibited by propofol and sevoflurane. In this study the authors tested the hypothesis that ketamine would also inhibit cortical feedback connectivity in frontoparietal networks.
G Landoni et al.
British journal of anaesthesia, 113(6), 955-963 (2014-09-05)
The effect of anaesthesia on postoperative outcome is unclear. Cardioprotective properties of volatile anaesthetics have been demonstrated experimentally and in haemodynamically stable patients undergoing coronary artery bypass grafting. Their effects in patients undergoing high-risk cardiac surgery have not been reported.
[Colonoscopy: propofol well suited for sedation].
Alexander Meining
Deutsche medizinische Wochenschrift (1946), 137(38), 1844-1844 (2012-09-14)
Mami Sasao-Takano et al.
Anesthesia progress, 60(2), 60-66 (2013-06-15)
The magnetic resonance imaging (MRI) room is a special environment. The required intense magnetic fields create unique problems with the use of standard anesthesia machines, syringe pumps, and physiologic monitors. We have recently experienced 2 oral maxillofacial surgery cases requiring
Weicheng Zhao et al.
Life sciences, 108(2), 80-87 (2014-06-01)
Both mast cells and oxidative stress are involved in acute lung injury (ALI) induced by intestinal ischemia-reperfusion (IIR). The aim of this study was to investigate whether propofol could improve IIR-induced ALI through inhibiting their interaction. Repetitive, brief IIR or
Luis I Cortínez et al.
Anesthesia and analgesia, 119(2), 302-310 (2014-07-01)
Obesity is associated with important physiologic changes that can potentially affect the pharmacokinetic (PK) and pharmacodynamic (PD) profile of anesthetic drugs. We designed this study to assess the predictive performance of 5 currently available propofol PK models in morbidly obese
Thoracic epidural anesthesia in abdominal aortic surgery: use and advantages.
Miguel Angel Palomero Rodríguez et al.
Anesthesiology, 120(5), 1288-1289 (2014-04-24)
Janos Peter Baombe et al.
Emergency medicine journal : EMJ, 30(1), 79-80 (2013-01-01)
A short-cut review was carried out to establish whether there was evidence to suggest that propofol should be avoided in patients with known egg allergy. Ninety-two papers were found in Medline using the reported searches, of which two presented the
C G Sheahan et al.
British journal of anaesthesia, 113 Suppl 2, ii37-ii47 (2014-12-17)
Sedation for medical procedures is provided in a variety of clinical settings by medical personnel with differing levels of education and training. Although generally a safe practice, there is a degree of morbidity and mortality associated with sedation practice. Monitoring
J B Glen et al.
Anaesthesia, 69(6), 550-557 (2014-04-12)
We compared the predictive performance of the existing Diprifusor and Schnider models, used for target-controlled infusion of propofol, with a new modification of the Diprifusor model (White) incorporating age and sex covariates. The bias and inaccuracy (precision) of each model
Jesse Willis et al.
Anesthesia and analgesia, 120(2), 433-439 (2014-11-13)
An imbalance between excitation and inhibition in the developing central nervous system may result in a pathophysiological outcome. We investigated the mechanistic roles of endocrine activity and γ-aminobutyric acid type A receptor (GABAAR)-mediated excitation in electroencephalographic seizures caused by the
Jörg Fechner et al.
Expert opinion on investigational drugs, 18(10), 1565-1571 (2009-09-18)
Today, propofol or 2,6-diisopropylphenol is the anesthetic mainly used for monitored anesthetic care sedation and during intravenous anesthesia. The formulation, a lipid macroemulsion, shows several disadvantages. Therefore, during the past years considerable scientific effort has been undertaken to find either
Zhi-Fu Wu et al.
Anesthesia and analgesia, 119(6), 1393-1406 (2014-09-12)
Anesthetic techniques can contribute to reduction of anesthesia-controlled time to improve operating room (OR) efficiency. However, little is known about the difference in anesthesia-controlled time between propofol-based total IV anesthesia (TIVA) and desflurane anesthesia (DES) techniques for ophthalmic surgery under
M M Sahinovic et al.
British journal of anaesthesia, 112(1), 110-117 (2013-11-05)
The influence of frontal brain tumours on bispectral index (BIS) measurements and propofol requirements is unknown. The primary aim of our study was to determine whether BIS values recorded at loss and return of consciousness (LOC and ROC, respectively) differ
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