搜索范围
P5629
应用筛选条件
关键词:'P5629'
显示 1-30 #N/A 403 条结果 关于 "P5629" 范围 论文
Johannes Bertsch et al.
Journal of bacteriology, 197(9), 1681-1689 (2015-03-04)
The methylenetetrahydrofolate reductase (MTHFR) of acetogenic bacteria catalyzes the reduction of methylene-THF, which is highly exergonic with NADH as the reductant. Therefore, the enzyme was suggested to be involved in energy conservation by reducing ferredoxin via electron bifurcation, followed by
Ganapathi Raj Murugesan et al.
Journal of the science of food and agriculture, 95(12), 2521-2527 (2014-11-05)
Efficacy of a multi-strain direct-fed microbial product (PoultryStar(®) ME; PS) and a xylanase enzyme product on the dietary energy utilization efficiency and resulting performance in broiler chickens was evaluated. Apart from performance parameters, cecal and serum metabolites and activities of
Elizabeth H Hart et al.
Veterinary parasitology, 207(3-4), 266-275 (2014-12-30)
The mechanisms involved in anthelmintic resistance (AR) are complex but a greater understanding of AR management is essential for effective and sustainable control of parasitic helminth worms in livestock. Current tests to measure AR are time consuming and can be
Alex J Wadley et al.
European journal of applied physiology, 115(8), 1757-1767 (2015-03-31)
This study investigated the impact of intensified training (IT) and carbohydrate (CHO) supplementation on resting and exercise-induced oxidative stress. Male cyclists (n = 13, mean ± SD: age 25 ± 6 years; [Formula: see text] 72 ± 5 ml/kg/min) undertook
Yujie Chang et al.
PloS one, 10(11), e0142952-e0142952 (2015-11-19)
Lysine is the most limiting essential amino acid for animal nutrition in maize grains. Expression of naturally lysine-rich protein genes can increase the lysine and protein contents in maize seeds. AtMAP18 from Arabidopsis thaliana encoding a microtubule-associated protein with high-lysine
Annette Ives et al.
Nature communications, 6, 6555-6555 (2015-03-25)
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by a rapid increase
Marcus Fischer et al.
The Journal of biological chemistry, 290(45), 27113-27123 (2015-09-08)
Tripartite ATP-independent periplasmic (TRAP) transporters are secondary transporters that have evolved an obligate dependence on a substrate-binding protein (SBP) to confer unidirectional transport. Different members of the DctP family of TRAP SBPs have binding sites that recognize a diverse range
Janne Hakkarainen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 3806-3816 (2015-05-29)
Hydroxysteroid (17β)-dehydrogenase type 1 (HSD17B1) catalyzes the conversion of low active 17-ketosteroids, androstenedione (A-dione) and estrone (E1) to highly active 17-hydroxysteroids, testosterone (T) and E2, respectively. In this study, the importance of HSD17B1 in ovarian estrogen production was determined using
Regulatory link between steryl ester formation and hydrolysis in the yeast Saccharomyces cerevisiae.
Birgit Ploier et al.
Biochimica et biophysica acta, 1851(7), 977-986 (2015-02-28)
Steryl esters and triacylglycerols are the major storage lipids of the yeast Saccharomyces cerevisiae. Steryl esters are formed in the endoplasmic reticulum by the two acyl-CoA:sterol acyltransferases Are1p and Are2p, whereas steryl ester hydrolysis is catalyzed by the three steryl
Yuanhong Shan et al.
Journal of chromatography. A, 1375, 101-109 (2014-12-17)
To develop a novel hybrid monolithic column based on pentafluorobenzyl imidazolium bromide ionic liquid, a new ionic liquid monomer was synthesized from 1-vinylimidazole and pentafluorobenzyl bromide. By employing a facile one-step copolymerization of polyhedral-oligomeric-silsesquioxane-type (POSS) cross-linking agent and the home-made
David W Koenig
Journal of cosmetic science, 65(2), 89-101 (2014-05-07)
Development of more effective products for cleansing the skin of microorganisms is enhanced by improved understanding of the mechanisms of attachment, as well as potential removal strategies. This paper describes an in vitro method for use of the cationic exchanger
Helene Blanchard et al.
Neurochemical research, 40(11), 2293-2303 (2015-09-26)
Brain serotonergic signaling is coupled to arachidonic acid (AA)-releasing calcium-dependent phospholipase A2. Increased brain serotonin concentrations and disturbed serotonergic neurotransmission have been reported in the Flinders Sensitive Line (FSL) rat model of depression, suggesting that brain AA metabolism may be
Maxim B Prigozhin et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(26), 7966-7971 (2015-06-17)
Fast protein folding involves complex dynamics in many degrees of freedom, yet microsecond folding experiments provide only low-resolution structural information. We enhance the structural resolution of the five-helix bundle protein λ6-85 by engineering into it three fluorescent tryptophan-tyrosine contact probes.
Adrian M Gospodarek et al.
Journal of chromatography. A, 1371, 204-219 (2014-12-03)
In hydrophobic interaction chromatography (HIC), interactions between buried hydrophobic residues and HIC surfaces can cause conformational changes that interfere with separations and cause yield losses. This paper extends our previous investigations of protein unfolding in HIC chromatography by identifying protein
Baoyu Zhao et al.
PloS one, 9(12), e115872-e115872 (2014-12-30)
Peptides are attracting increasing interest as protease inhibitors. Here, we demonstrate a new inhibitory mechanism and a new type of exosite interactions for a phage-displayed peptide library-derived competitive inhibitor, mupain-1 (CPAYSRYLDC), of the serine protease murine urokinase-type plasminogen activator (uPA).
Claire M Hull et al.
AMB Express, 4, 64-64 (2014-11-18)
Microbial biotechnology and biotransformations promise to diversify the scope of the biorefinery approach for the production of high-value products and biofuels from industrial, rural and municipal waste feedstocks. In addition to bio-based chemicals and metabolites, microbial biomass itself constitutes an
Stephanie N Joslin et al.
Infection and immunity, 83(1), 146-160 (2014-10-15)
There are a paucity of data concerning gene products that could contribute to the ability of Moraxella catarrhalis to colonize the human nasopharynx. Inactivation of a gene (mesR) encoding a predicted response regulator of a two-component signal transduction system in
H Guo et al.
Scandinavian journal of immunology, 81(2), 129-134 (2014-12-03)
Liver ischaemia/reperfusion injury (IRI) is a serious pathologic process encountered in a number of clinical syndromes including liver transplantation, liver resection, trauma and haemorrhagic shock. Platelet factor 4 (PF4) was the first discovered CXC chemokine and is found in platelet
Raghuvaran Shanmugam et al.
Nucleic acids research, 42(10), 6487-6496 (2014-04-09)
Dnmt2 enzymes are conserved in eukaryotes, where they methylate C38 of tRNA-Asp with high activity. Here, the activity of one of the very few prokaryotic Dnmt2 homologs from Geobacter species (GsDnmt2) was investigated. GsDnmt2 was observed to methylate tRNA-Asp from
Debashree Basudhar et al.
The Journal of biological chemistry, 290(16), 10000-10017 (2015-02-12)
Defining the conformational states of cytochrome P450 active sites is critical for the design of agents that minimize drug-drug interactions, the development of isoform-specific P450 inhibitors, and the engineering of novel oxidative catalysts. We used two-dimensional (1)H,(15)N HSQC chemical shift
Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system.
Paul S Baxter et al.
Nature communications, 6, 6761-6761 (2015-04-10)
How the brain's antioxidant defenses adapt to changing demand is incompletely understood. Here we show that synaptic activity is coupled, via the NMDA receptor (NMDAR), to control of the glutathione antioxidant system. This tunes antioxidant capacity to reflect the elevated
Chikako Sakaguchi et al.
Regulatory toxicology and pharmacology : RTP, 69(3), 338-347 (2014-05-14)
The objective of this clinical study was to investigate changes in levels of biomarkers of exposure (BOEs) in healthy Japanese male smokers who switched to a prototype heated cigarette (HC). This was a controlled, semi-randomized, open-label, residential study conducted in
Shogo Nakano et al.
Scientific reports, 5, 13836-13836 (2015-09-16)
Alkaline D-peptidase from Bacillus cereus DF4-B, called ADP, is a D-stereospecific endopeptidase reacting with oligopeptides containing D-phenylalanine (D-Phe) at N-terminal penultimate residue. ADP has attracted increasing attention because it is useful as a catalyst for synthesis of D-Phe oligopeptides or
Chin-Cheng Su
Anticancer research, 34(12), 7097-7110 (2014-12-17)
Tanshinone IIA (Tan-IIA) is extracted from Danshen (Salviae miltiorrhizae radix). It possesses antitumor activity against a variety of human cancer cells and its induction of apoptosis and inhibition of proliferation of gastric cancer cells are well-documented. However, the molecular mechanisms
Raksha Dodia et al.
The Biochemical journal, 464(3), 335-342 (2014-09-23)
Subunit 5 of Saccharomyces cerevisiae cytochrome c oxidase (CcO) is essential for assembly and has two isoforms, 5A and 5B. 5A is expressed under normoxic conditions, whereas 5B is expressed at very low oxygen tensions. As a consequence, COX5A-deleted strains
R Krishnamurthy et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 310-314 (2013-01-01)
Potassium Dihydrogen Phosphate (KDP) doped with L-aspartic acid has been grown by solvent slow evaporation technique from a mixture of aqueous solution of KDP and 0.7% of L-aspartic acid at room temperature. The grown crystals were characterized by powder X-ray
Rym Hassani et al.
Chemico-biological interactions, 217, 41-48 (2014-04-15)
This paper describes the synthesis of new enantiomerically pure 2-cyanoethyl-oxazolines in one step starting from a wide range of amino alcohols and 4-ethoxy-4-iminobutanenitrile with high to good yields (73-96%) via an appropriate procedure which can be used for a selective
James E Erman et al.
Biochemistry, 54(31), 4845-4854 (2015-07-28)
Previously, we constructed, expressed, and purified 46 charge-reversal mutants of yeast cytochrome c peroxidase (CcP) and determined their electronic absorption spectra, their reaction with H2O2, and their steady-state catalytic properties [ Pearl , N. M. et al. (2008) Biochemistry 47
Kewei Chen et al.
Journal of chromatography. A, 1412, 90-99 (2015-08-19)
Dephytylated chlorophylls (chlorophyllides and pheophorbides) are the starting point of the chlorophyll catabolism in green tissues, components of the chlorophyll pattern in storage/processed food vegetables, as well as the favoured structural arrangement for chlorophyll absorption. In addition, dephytylated native chlorophylls
Alexandra Jammer et al.
Journal of experimental botany, 66(18), 5531-5542 (2015-05-24)
The analysis of physiological parameters is important to understand the link between plant phenotypes and their genetic bases, and therefore is needed as an important element in the analysis of model and crop plants. The activities of enzymes involved in
1/14