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PHR1047
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显示 1-30 #N/A 436 条结果 关于 "PHR1047" 范围 论文
S Cyboran et al.
Life sciences, 126, 1-9 (2015-02-24)
This study was undertaken to determine the biological activity of a green tea supplement with respect to cells and erythrocyte membranes and the molecular mechanism of that activity. The extract's activity was evaluated on the basis of its hemolytic, antioxidant
Saori Ishizaka et al.
Journal of equine science, 25(4), 65-72 (2015-01-06)
The effects of probiotics on horses are still controversial. The present study was a randomized, double-blinded, placebo-controlled crossover study designed to evaluate the ability of probiotics to improve intestinal conditions in adult horses. Fermented probiotics were administered to 10 healthy
Paul-Andre Genest et al.
Nucleic acids research, 43(4), 2102-2115 (2015-02-11)
Base J (β-D-glucosyl-hydroxymethyluracil) replaces 1% of T in the Leishmania genome and is only found in telomeric repeats (99%) and in regions where transcription starts and stops. This highly restricted distribution must be co-determined by the thymidine hydroxylases (JBP1 and
Josh M Morganti et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 748-760 (2015-01-16)
Traumatic brain injury (TBI) is a major risk factor for the development of multiple neurodegenerative diseases. With respect to the increasing prevalence of TBI, new therapeutic strategies are urgently needed that will prevent secondary damage to primarily unaffected tissue. Consistently
Joshua J Corrigan et al.
The Journal of physiology, 592(17), 3901-3916 (2014-06-22)
We tested the hypothesis that development of hypothermia instead of fever in endotoxic shock is consequential to hypoxia. Endotoxic shock was induced by bacterial lipopolysaccharide (LPS, 500 μg kg(-1) i.v.) in rats at an ambient temperature of 22 °C. A
Yohei Sakaguchi et al.
The Analyst, 140(6), 1965-1973 (2015-02-12)
We have developed a novel amino acid analysis method using derivatization of multiple functional groups (amino, carboxyl, and phenolic hydroxyl groups). The amino, carboxyl, and phenolic hydroxyl groups of the amino acids were derivatized with 1-bromobutane so that the hydrophobicities
Jiaqi Shi et al.
Environmental science and pollution research international, 20(9), 6138-6149 (2013-04-03)
The lethal doses (LD50s) of fluorinated, chlorinated, brominated, and iodinated benzene, phenol, and diphenyl ether in mice were ascertained respectively under the consistent condition. The acute toxicity of four benzenes orders in fluorobenzene (FB) < iodobenzene < chlorobenzene≈bromobenzene, that of four phenols orders in
Yang Li et al.
Toxicology, 312, 108-114 (2013-08-27)
Benzene is a common occupational hazard as well as a widespread pollutant. Its metabolites play important roles in its toxicity to the hematopoietic system, but little is known about how benzene metabolites affect erythropoiesis. Our previous study demonstrated that benzene
Dasha Mihaylova et al.
Journal of food science and technology, 52(4), 2469-2473 (2015-04-02)
The antioxidant capacity of extracts from leaves of Haberlea rhodopensis Friv. obtained by a highly efficient and simple method of the ultrasound-assisted extraction was investigated. The total polyphenolic content was determined spectrophotometrically using the Folin - Ciocalteu's phenol reagent and the polyphenols
Elina Jääskeläinen et al.
Applied and environmental microbiology, 81(6), 1902-1908 (2014-12-31)
Leuconostoc gelidum subsp. gasicomitatum is a common spoilage bacterium in meat products packaged under oxygen-containing modified atmospheres. Buttery off-odors related to diacetyl/acetoin formation are frequently associated with the spoilage of these products. A whole-genome microarray study, together with gas chromatography
Juliana Comerlato et al.
Journal of medical virology, 87(3), 522-528 (2015-01-22)
The human polyomaviruses JC (JCPyV) and BK (BKPyV) are widespread in the human population. Following the primary infection, virus reactivation may lead to nephropathy and graft rejection in renal transplant patients. This study was carried out to access the presence
Ai-Cheng Lee et al.
The Analyst, 139(17), 4223-4230 (2014-06-26)
We describe an ultrasensitive electrochemical nucleic acid assay amplified by carbon nanotubes (CNTs)-based labels for the detection of human acute lymphocytic leukemia (ALL)-related p185 BCR-ABL fusion transcript. The carboxylated CNTs were functionalized with horseradish peroxidase (HRP) molecules and target-specific detection
L Ciofi et al.
Journal of chromatography. A, 1362, 75-88 (2014-08-31)
Four different pellicular stationary phases (i.e. octadecylsilane, octasilane, Phenyl-Hexyl and pentafluorophenyl) were investigated for the chromatographic resolution of alkylphenols (APs), alkylphenols polyethoxylates (APnEOs) and alkylphenoxy carboxylates (APECs) using mixtures of water and organic solvents (i.e. methanol, acetonitrile and tetrahydrofuran) as
Maarke J E Roelofs et al.
Toxicology, 329, 10-20 (2015-01-13)
Although much information on the endocrine activity of bisphenol A (BPA) is available, a proper human hazard assessment of analogues that are believed to have a less harmful toxicity profile is lacking. Here the possible effects of BPA, bisphenol F
W F Tonnis et al.
Molecular pharmaceutics, 12(3), 684-694 (2015-01-13)
Protein-based biopharmaceuticals are generally produced as aqueous solutions and stored refrigerated to obtain sufficient shelf life. Alternatively, proteins may be freeze-dried in the presence of sugars to allow storage stability at ambient conditions for prolonged periods. However, to act as
Y Asai et al.
Journal of dental research, 84(5), 456-461 (2005-04-21)
Oral treponemes are well-known as causative agents of periodontal diseases; however, the details have not been fully clarified. Here, we examined the effects of Treponema medium glycoconjugate on the activation of human gingival fibroblasts using phenol-water extracts from Porphyromonas gingivalis
Jie Ma et al.
Virus research, 189, 47-55 (2014-05-23)
The hemorrhagic disease of grass carp (Ctenopharyngodon idellus), caused by grass carp reovirus (GCRV), is the most severe disease of the fish that leads to huge economic losses. GCRV, belonging to the genus Aquareovirus of the family Reoviridae, has been
Christina A Von Roemeling et al.
Oncotarget, 5(14), 5320-5334 (2014-07-01)
Currently there is a lack of targeted therapies that lead to long-term attenuation or regression of disease in patients with advanced clear cell renal cell carcinoma (ccRCC). Our group has implemented a high-throughput genetic analysis coupled with a high-throughput proliferative
Su-Hsia Lin et al.
Journal of environmental management, 90(3), 1336-1349 (2008-11-11)
In this article, the technical feasibility of the use of activated carbon, synthetic resins, and various low-cost natural adsorbents for the removal of phenol and its derivatives from contaminated water has been reviewed. Instead of using commercial activated carbon and
H Tatsumi et al.
Acta obstetrica et gynaecologica Japonica, 33(5), 643-650 (1981-05-01)
A simple and sensitive procedure for the quantitative estimation of pulmonary surfactants in the amniotic fluid is described. The method is based on the formation of turbidity from the amniotic fluid surfactants with phenol. Amniotic fluid drawn through an intrauterine
Se-Jin Yoon et al.
Nature communications, 6, 6546-6546 (2015-03-17)
In embryonic stem cells, extracellular signals are required to derepress developmental promoters to drive lineage specification, but the proteins involved in connecting extrinsic cues to relaxation of chromatin remain unknown. We demonstrate that the helix-loop-helix (HLH) protein, HEB, directly associates
Yeojun Yun et al.
PloS one, 9(12), e113466-e113466 (2014-12-04)
Commensal bacteria control the micro-ecology of metazoan epithelial surfaces with pivotal effect on tissue homeostasis and host defense. In contrast to the upper respiratory tract, the lower respiratory tract of healthy individuals has largely been considered free of microorganisms. To
Bernardo Ramírez-Zavala et al.
Antimicrobial agents and chemotherapy, 58(9), 5102-5110 (2014-06-18)
Overexpression of the multidrug efflux pump MDR1 is one mechanism by which the pathogenic yeast Candida albicans develops resistance to the antifungal drug fluconazole. The constitutive upregulation of MDR1 in fluconazole-resistant, clinical C. albicans isolates is caused by gain-of-function mutations
Heather M Wilkins et al.
Journal of Alzheimer's disease : JAD, 45(1), 305-318 (2014-12-30)
Neuroinflammation occurs in Alzheimer's disease (AD). While AD genetic studies implicate inflammation-relevant genes and fibrillar amyloid-β protein promotes inflammation, our understanding of AD neuroinflammation nevertheless remains incomplete. In this study we hypothesized damage-associated molecular pattern (DAMP) molecules arising from mitochondria
Yan Wang et al.
Environmental toxicology, 29(12), 1437-1451 (2013-06-19)
Benzene-induced erythropoietic depression has been proposed to be due to the production of toxic metabolites. Presently, the cytotoxicities of benzene metabolites, including phenol, catechol, hydroquinone, and 1,2,4-benzenetriol, to erythroid progenitor-like K562 cells were investigated. After exposure to these metabolites, K562
Sylvia P F Omena et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(5), 581-591 (2013-02-07)
The general purpose of this study was to characterize a biological treatment system for phenol removal in an anoxic fluidized bed reactor (AFBR) that employed nitrate as the final electron acceptor. The average influent phenol concentrations in the study were
Wagdy K B Khalil et al.
Neurochemistry international, 80, 79-86 (2014-12-08)
Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by dopaminergic neurodegeneration, mitochondrial impairment, and oxidative stress. Exposure of animals to rotenone induces a range of responses characteristic of PD, including reactive oxygen species production and dopaminergic cell
Yong Sun et al.
PloS one, 9(12), e113818-e113818 (2014-12-03)
Banana Fusarium wilt is a soil-spread fungal disease caused by Fusarium oxysporum. In China, the main virulence fungi in banana are F. oxysporum race 1 (F1, weak virulence) and race 4 (F4, strong virulence). To date, no proteomic analyses have
M Bauer et al.
Forensic science international, 136(1-3), 76-78 (2003-09-13)
The origin of forensic stains can be determined by detection of cell- and tissue-specific messenger-RNA (mRNA) using reverse transcription-polymerase chain reaction (RT-PCR) as demonstrated recently by the authors. However, in cases with limited sample amount DNA analysis has priority in
Kashif Naeem et al.
Journal of environmental sciences (China), 25(2), 399-404 (2013-04-20)
The photocatalytic degradation of phenol and 4-chlorophenol (4-CP) in aqueous suspensions with the use of titanium dioxide (TiO2) under UV irradiation was examined. The effects of different supporting materials mixed physically with TiO2 were studied to achieve maximum degradation efficiency.
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