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C-h Lian et al.
Mycoses, 57(12), 759-764 (2014-08-16)
The genus Malassezia is important in the aetiology of facial seborrhoeic dermatitis (FSD), which is the most common clinical type. The purpose of this study was to analyse the distribution of Malassezia species in the facial lesions of Chinese seborrhoeic
Melissa Dsouza et al.
PloS one, 9(10), e108009-e108009 (2014-10-07)
Antarctic soils represent a unique environment characterised by extremes of temperature, salinity, elevated UV radiation, low nutrient and low water content. Despite the harshness of this environment, members of 15 bacterial phyla have been identified in soils of the Ross
Jennifer A Muszynski et al.
Shock (Augusta, Ga.), 42(4), 313-321 (2014-07-01)
Critical injury has been associated with reduction in innate immune function in adults, with infection risk being related to degree of immune suppression. This relationship has not been reported in critically injured children. Innate immune function will be reduced in
C Flavia Massaro et al.
Phytotherapy research : PTR, 29(1), 48-58 (2014-09-19)
Stingless bees accumulate deposits of plant resins that are mixed with beeswax to produce propolis. Previous studies have reported anti-microbial constituents of stingless bee (Tetragonula carbonaria) propolis from East Australia, but several components remained to be characterized. In the search
Jihong Li et al.
Infection and immunity, 82(11), 4620-4630 (2014-08-20)
Previous studies showed that Clostridium perfringens type D animal disease strain CN3718 uses NanI sialidase for adhering to enterocyte-like Caco-2 cells. The current study analyzed whether NanI is similarly important when type A and C human intestinal disease strains attach
Dana J Wohlbach et al.
Genome biology and evolution, 6(9), 2557-2566 (2014-11-05)
Lignocellulosic plant material is a viable source of biomass to produce alternative energy including ethanol and other biofuels. However, several factors—including toxic by products from biomass pretreatment and poor fermentation of xylose and other pentose sugars—currently limit the efficiency of
Rosario Sánchez-Gómez et al.
Journal of agricultural and food chemistry, 62(45), 10861-10872 (2014-10-23)
Vine-shoots are an important waste in all viticulture areas that should be re-used with innovative applications. The aim of this work was to produce Airén waste vine-shoot aqueous extracts by four solid-liquid extraction techniques such as conventional solid-liquid extraction (CSLE)
V A Baraboĭ et al.
Ukrainskii biokhimicheskii zhurnal (1978), 70(6), 13-23 (1999-07-14)
The article analyses critically the date from literature as well as own date concerning appropriateness and mechanisms of antiradiation, capillary strengthening and antistress effect of plant phenolic compounds. Knowledge on antioxidant effect as the most fundamental mechanism being in the
William L Miller et al.
Eye & contact lens, 30(3), 132-137 (2004-10-23)
Various measures are available to assess the tear film, yet little specific information is available on how they relate to each other. An exploratory study was undertaken to assess three measures and their relationship in non-contact lens wearers and in
Carmela Fimognari et al.
PloS one, 9(7), e101991-e101991 (2014-07-16)
Sulforaphane is a dietary isothiocyanate found in cruciferous vegetables showing antileukemic activity. With the purpose of extending the potential clinical impact of sulforaphane in the oncological field, we investigated the antileukemic effect of sulforaphane on blasts from patients affected by
I C Le Poole et al.
The Journal of investigative dermatology, 113(5), 725-731 (1999-11-26)
Exposure to phenolic agents contributes to the development of occupational vitiligo. Proposed as a causative factor for leukoderma in vivo, the para-substituted phenol 4-tertiary butyl phenol was chosen to investigate early cellular events responsible for selective disappearance of melanocytes from
Akiko Naitou et al.
Biology open, 4(3), 364-369 (2015-02-15)
Transcription activator-like effector nucleases (TALENs) are artificial nucleases harboring a customizable DNA-binding domain and a FokI nuclease domain. The high specificity of the DNA-binding domain and the ease of design have enabled researchers to use TALENs for targeted mutagenesis in
D-z Yuan et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 46(11), 761-767 (2014-07-10)
Under normal conditions, progesterone inhi-bits the estrogen-induced proliferation of endometrial epithelium. Our previous studies have shown that cyclin G1 was progesterone-dependent in mouse endometrial epithelium at peri-implantation, and exogenous cyclin G1 suppressed the proliferation of endometrial cancer cells. The objectives
M F Meiboom et al.
Biochimica et biophysica acta, 1828(11), 2564-2573 (2013-06-25)
Why do anesthetics not activate excitatory ligand-gated ion channels such as 5-HT3 receptors in contrast to inhibitory ligand-gated ion channels? This study examines the actions of structural closely-related 5-HT derivatives and 5-HT constituent parts on 5-HT3A receptors with the aim
Talent Chipiti et al.
Acta poloniae pharmaceutica, 72(1), 119-127 (2015-04-09)
The study was intended to explore the antioxidant potential and phytochemical content of the ethanol and aqueous extracts of the leaf and root samples of Cissus cornifolia (Baker) Splanch (Vitaceae) across a series of four in vitro models. The results
Florencia Chiappini et al.
Toxicology letters, 230(1), 1-9 (2014-08-06)
Hexachlorobenzene (HCB) is an organochlorine pesticide widely distributed in the environment. In this study we have demonstrated that HCB induced loss of cell viability and alterations in cell cycle regulation in FRTL-5 rat thyroid cells. Analysis of cell cycle distribution
Claudio R Alarcón et al.
Nature, 519(7544), 482-485 (2015-03-25)
The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-miRNAs) by the microprocessor complex, composed of the RNA-binding protein DGCR8 and the type III RNase DROSHA. This initial event requires recognition of the junction between
Soon Young Shin et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(16), 4302-4313 (2014-06-19)
The selective killing of tumor cells is an important strategy for cancer therapeutics. The aim of this study was to develop a novel antitumor agent that is safe for normal cells with the ability to selectively target cancer cells. On
Ahmad Ibrahim Husein et al.
Pharmaceutical biology, 52(10), 1249-1255 (2014-05-28)
Despite several pharmacological applications of the medicinal plants in the Traditional Arabic Palestinian Herbal Medicine in Palestine (TAPHM), studies on their antioxidant properties are still scarce. This work evaluates the antioxidant and antitumor activities of the ethanol extracts from different
L E Bartholomew et al.
Arthritis and rheumatism, 22(9), 969-977 (1979-09-01)
Phenol-water extracted rheumatoid synovial fluids and synovial fluid leukocytes contain an antigen immunologically identical to the Proprionibacterium group bacteria. The antigen was identified by counter-immunoelectrophoresis in 70% of rheumatoid synovial fluid leukocyte pellets and in 60% of rheumatoid synovial fluids.
Phenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 47, 263-287 (1989-01-01)
Babett Steglich et al.
PLoS genetics, 11(3), e1005101-e1005101 (2015-03-24)
In eukaryotic cells, local chromatin structure and chromatin organization in the nucleus both influence transcriptional regulation. At the local level, the Fun30 chromatin remodeler Fft3 is essential for maintaining proper chromatin structure at centromeres and subtelomeres in fission yeast. Using
Catarina L Silva et al.
Talanta, 89, 360-368 (2012-01-31)
A sensitive assay to identify volatile organic metabolites (VOMs) as biomarkers that can accurately diagnose the onset of breast cancer using non-invasively collected clinical specimens is ideal for early detection. Therefore the aim of this study was to establish the
Jesus A Segovia et al.
Molecular and cellular biology, 35(3), 582-597 (2014-12-03)
Caspase-1 is activated by the inflammasome complex to process cytokines like interleukin-1β (IL-1β). Pro-caspase-1 consists of three domains, CARD, p20, and p10. Association of pro-caspase-1 with the inflammasome results in initiation of its autocatalytic activity, culminating in self-cleavage that generates
Timucin Uğurlu et al.
Acta poloniae pharmaceutica, 71(2), 311-321 (2014-10-03)
The purpose of the study was to prepare and evaluate clarithromycin (CLA) floating tablets using experimental mixture design for treatment of Helicobacter pylori provided by prolonged gastric residence time and controlled plasma level. Ten different formulations were generated based on
Mélanie Bonizec et al.
Nucleic acids research, 42(17), 10975-10986 (2014-09-04)
Cdc48/p97 is an evolutionary conserved ubiquitin-dependent chaperone involved in a broad array of cellular functions due to its ability to associate with multiple cofactors. Aside from its role in removing RNA polymerase II from chromatin after DNA damage, little is
Michael R Botts et al.
Eukaryotic cell, 13(9), 1158-1168 (2014-07-09)
Among pathogenic environmental fungi, spores are thought to be infectious particles that germinate in the host to cause disease. The meningoencephalitis-causing yeast Cryptococcus neoformans is found ubiquitously in the environment and sporulates in response to nutrient limitation. While the yeast
Nirton C S Vieira et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 3899-3902 (2013-08-06)
This paper reports on the use of the crude extract of avocado (CEA) fruit (Persea americana) as a source of tyrosinase enzyme. CEA was immobilized via layer by layer (LbL) technique onto indium tin oxide (ITO) substrates and applied in
Z L Kiss et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(6), 1272-1279 (2013-03-20)
After their use for heating, e.g. in greenhouses, waste thermal waters may cause environmental problems due to their high contents of ions, and in some cases organic matter (associated with an oxygen demand) or toxic compounds. The aims of this
Biju Prava Sahariah et al.
Environmental technology, 34(1-4), 245-256 (2013-03-28)
Performance of a fed batch moving-bed reactor system arranged in anaerobic (B1)-anoxic (B2)-aerobic (B3) mode was investigated using cycle time (18-36h), gradual fill time (total 5-18.5 h; B1: 1-3.7 h; B2 and B3: 2-7.4 h each) and instantaneous fill time
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