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显示 31-60 共 436 条结果 关于 "PHR1047" 范围 论文
Tian-Yao Yang et al.
Environmental toxicology and pharmacology, 39(1), 157-166 (2014-12-20)
MeHg is one of the environmental pollutants that lead to oxidative stress and an indirect excitotoxicity caused by altered glutamate (Glu) concentration. However, little was known of the interaction. Therefore, we developed a rat model of MeHg poisoning to explore
Yu Zhou et al.
Ophthalmic genetics, 36(1), 43-49 (2014-11-25)
Genetic factors have been studied extensively for their role in the pathogenesis of primary open angle glaucoma (POAG). This study was conducted to investigate whether manganese superoxide dismutase (SOD2) variants play a significant role in POAG in a Chinese population.
Determination of trace amounts of phenol in river waters by gas chromatography
Rennie.JP
Analyst, 107, 327-330 (1982)
W Liu et al.
Free radical research, 48(8), 849-863 (2014-05-14)
Methylmercury (MeHg) is a ubiquitous environmental contaminant that could induce oxidative stress and an indirect glutamate (Glu)-mediated excitotoxicity. However, the underlying mechanisms through which MeHg affects the central nervous system have not been fully elucidated, and little has been known
Kevin Guo et al.
Analytical chemistry, 81(10), 3919-3932 (2009-03-25)
We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass spectrometry (ESI-FTICR MS) detection. An isotope reagent, (13)C-dansyl chloride, can be
Britta T Eklund et al.
Marine pollution bulletin, 46(2), 171-181 (2003-02-15)
Toxic effects on macroalgae have been compiled. Eighty-two articles have been found in literature during 1959-2000. A total of 120 substances were investigated using 65 different macroalgae species. About one-third of the tested compounds were organic substances (33%), another third
T Geetha et al.
Journal of drug targeting, 23(2), 159-169 (2014-10-01)
Abstract Role of reactive oxygen species (ROS) in skin carcinogenesis is well documented. Natural molecules, like sesamol, with marked antioxidant potential can be useful in combating skin cancers. In vitro antiproliferative (using MTT assay) and DNA fragmentation studies in HL
Julie Kim et al.
Talanta, 129, 106-112 (2014-08-17)
Using the role of p-iodophenol in enzyme assay, enhanced 1,1'-oxalyldiimidazole chemiluminescent enzyme immunoassays (ODI-CLEIAs) were developed to consecutively quantify trace levels of triple tumor markers, such as alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), and prostate specific antigen (PSA) in a
Hichem Alimi et al.
General physiology and biophysics, 32(1), 115-127 (2013-03-28)
Rhus tripartitum (sumac) is an Anacardiaceae tree with a wide phytotherapeutic application including the use of its roots in the management of gastric ulcer. In the present study the Rhus tripartitum root barks extract (RTE) was phytochemical studied, in vitro
Catarina L Silva et al.
Talanta, 89, 360-368 (2012-01-31)
A sensitive assay to identify volatile organic metabolites (VOMs) as biomarkers that can accurately diagnose the onset of breast cancer using non-invasively collected clinical specimens is ideal for early detection. Therefore the aim of this study was to establish the
Mounira Krifa et al.
Drug and chemical toxicology, 38(1), 84-91 (2014-04-15)
Evaluation of the immunomodulatory activity of plant extracts is an interesting and growing area of research. In this study, effects of a methanolic extract of Limoniastrum guyonianum stems (M extract) on mice immune cell function in vitro were investigated. These
Guillermo Marcial et al.
Journal of ethnopharmacology, 155(2), 1125-1133 (2014-07-06)
The aerial parts of Lippia integrifolia (Gris.) Hieronymus (Verbenaceae), known as incayuyo, are used by the peasant population of Argentina for treatment of diseases related to a gastrointestinal system, mainly for inflammation of the stomach and have also been included
Mélanie Bonizec et al.
Nucleic acids research, 42(17), 10975-10986 (2014-09-04)
Cdc48/p97 is an evolutionary conserved ubiquitin-dependent chaperone involved in a broad array of cellular functions due to its ability to associate with multiple cofactors. Aside from its role in removing RNA polymerase II from chromatin after DNA damage, little is
Michael R Botts et al.
Eukaryotic cell, 13(9), 1158-1168 (2014-07-09)
Among pathogenic environmental fungi, spores are thought to be infectious particles that germinate in the host to cause disease. The meningoencephalitis-causing yeast Cryptococcus neoformans is found ubiquitously in the environment and sporulates in response to nutrient limitation. While the yeast
Babett Steglich et al.
PLoS genetics, 11(3), e1005101-e1005101 (2015-03-24)
In eukaryotic cells, local chromatin structure and chromatin organization in the nucleus both influence transcriptional regulation. At the local level, the Fun30 chromatin remodeler Fft3 is essential for maintaining proper chromatin structure at centromeres and subtelomeres in fission yeast. Using
Nirton C S Vieira et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 3899-3902 (2013-08-06)
This paper reports on the use of the crude extract of avocado (CEA) fruit (Persea americana) as a source of tyrosinase enzyme. CEA was immobilized via layer by layer (LbL) technique onto indium tin oxide (ITO) substrates and applied in
Jung-Ho Shin et al.
PLoS genetics, 10(6), e1004429-e1004429 (2014-06-27)
Magnesium is an essential divalent metal that serves many cellular functions. While most divalent cations are maintained at relatively low intracellular concentrations, magnesium is maintained at a higher level (∼0.5-2.0 mM). Three families of transport proteins were previously identified for
José P Vaqué et al.
PloS one, 10(3), e0119946-e0119946 (2015-03-17)
We have performed a comparative ultrasequencing study of multiple colorectal lesions obtained simultaneously from four patients. Our data show that benign lesions (adenomatous or hyperplastic polyps) contain a high mutational load. Additionally multiple synchronous colorectal lesions show non overlapping mutational
Taichi Kamiunten et al.
Histochemistry and cell biology, 143(3), 259-266 (2014-10-09)
Tissue-specific gene expression is subjected to epigenetic and genetic regulation. Posttranslational modifications of histone tails alter the accessibility of nuclear proteins to DNA, thus affecting the activity of the regulatory complex of nuclear proteins. Methylation at histone 3 lysine 9
Xiao Yan Chen et al.
Applied and environmental microbiology, 80(18), 5752-5760 (2014-07-13)
Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in piglets; ETEC cells colonize the intestinal mucosa with adhesins and deliver toxins that cause fluid loss. This study determined the antiadhesive properties of bacterial exopolysaccharides (reuteran and levan) and
Timucin Uğurlu et al.
Acta poloniae pharmaceutica, 71(2), 311-321 (2014-10-03)
The purpose of the study was to prepare and evaluate clarithromycin (CLA) floating tablets using experimental mixture design for treatment of Helicobacter pylori provided by prolonged gastric residence time and controlled plasma level. Ten different formulations were generated based on
Jesus A Segovia et al.
Molecular and cellular biology, 35(3), 582-597 (2014-12-03)
Caspase-1 is activated by the inflammasome complex to process cytokines like interleukin-1β (IL-1β). Pro-caspase-1 consists of three domains, CARD, p20, and p10. Association of pro-caspase-1 with the inflammasome results in initiation of its autocatalytic activity, culminating in self-cleavage that generates
M F Meiboom et al.
Biochimica et biophysica acta, 1828(11), 2564-2573 (2013-06-25)
Why do anesthetics not activate excitatory ligand-gated ion channels such as 5-HT3 receptors in contrast to inhibitory ligand-gated ion channels? This study examines the actions of structural closely-related 5-HT derivatives and 5-HT constituent parts on 5-HT3A receptors with the aim
Phenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 47, 263-287 (1989-01-01)
Dana J Wohlbach et al.
Genome biology and evolution, 6(9), 2557-2566 (2014-11-05)
Lignocellulosic plant material is a viable source of biomass to produce alternative energy including ethanol and other biofuels. However, several factors—including toxic by products from biomass pretreatment and poor fermentation of xylose and other pentose sugars—currently limit the efficiency of
Christos Andreadis et al.
Nucleic acids research, 42(20), 12650-12667 (2014-10-11)
DNA damage response and repair proteins are centrally involved in genome maintenance pathways. Yet, little is known about their functional role under non-DNA damage-inducing conditions. Here we show that Rad9 checkpoint protein, known to mediate the damage signal from upstream
Z-H He et al.
Scandinavian journal of medicine & science in sports, 25(2), 184-195 (2014-08-30)
This study aims to examine the association between proliferator-activated receptor γ (PGC)-gene family-related single nucleotide polymorphisms (SNPs) and elite endurance runners' status in a Chinese cohort, and to gain insights into the functionality of a subset of SNPs. Genotype distributions
Jin Wang et al.
Cancer letters, 356(2 Pt B), 404-409 (2014-10-12)
Intraductal papillary mucinous neoplasm (IPMN) is a precursor cystic lesion to pancreatic cancer. With the goal of classifying IPMN cases by risk of progression to pancreatic cancer, we undertook an exploratory next generation sequencing (NGS) based profiling study of miRNAs
C D Wu et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1620-1626 (2013-04-05)
The feasibility of using raw diatomite and aluminum hydroxide-modified diatomite (Al-diatomite) for removal of aniline and phenol from water was investigated. Their physicochemical characteristics such as pHsolution, point of zero charge (pHPZC), surface area, Fourier transform infrared (FT-IR) and scanning
Practice parameters for the management of pilonidal disease.
Scott R Steele et al.
Diseases of the colon and rectum, 56(9), 1021-1027 (2013-08-10)
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