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Marcin Barczyński et al.
Annals of surgery, 260(5), 740-747 (2014-09-23)
To test if posterior retroperitoneoscopic adrenalectomy (PRA) is superior to lateral transperitoneal laparoscopic adrenalectomy (LTLA). Most popular LTLA has been recently challenged by an increasing popularity of PRA, which is believed by many surgeons (not evidence-based) as superior to LTLA
Carmen Cantisani et al.
Recent patents on inflammation & allergy drug discovery, 4(1), 58-64 (2009-10-17)
Topical ketoprofen (KP) is widely used because of its anti-inflammatory effect. Parallel with its popular usage, the number of reported cases of ketoprofen-induced photoallergic contact dermatitis has increased. A review of the literature was made to evaluate the spectrum of
Hannu Kokki
Paediatric drugs, 12(5), 313-329 (2010-08-31)
The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal conditions, pain, and fever in children and adults. Pharmacokinetic studies show that drug exposure after a single intravenous dose is similar in children and adults (after dose
H Adachi et al.
European review for medical and pharmacological sciences, 15(7), 823-830 (2011-07-26)
The mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs), to which ketoprofen belongs, is based on their cyclo-oxigenase (COX) inhibiting action, concerning both subtype COX-1 constitutive isoform and COX-2 inducible isoform. Ketoprofen administration may be carried out by oral and
Aleksandar Lolić et al.
The Science of the total environment, 508, 240-250 (2014-12-08)
The occurrence of seven pharmaceuticals and two metabolites belonging to non-steroidal anti-inflammatory drugs and analgesics therapeutic classes was studied in seawaters. A total of 101 samples covering fourteen beaches and five cities were evaluated in order to assess the spatial
P Sarzi-Puttini et al.
Reumatismo, 62(3), 172-188 (2010-11-06)
Ketoprofen is a drug belonging to the family of non-steroidal anti-inflammatory drugs (NSAIDs). The present review examines the main available clinical evidence of ketoprofen in the treatment of acute and chronic pain, of both rheumatic and traumatic origin, as well
Piercarlo Sarzi-Puttini et al.
Clinical and experimental rheumatology, 31(5), 731-738 (2013-05-29)
The aim of this systematic review of the literature and meta-analysis of randomised controlled trials (RCTs) was to compare the efficacy of orally administered ketoprofen with that of ibuprofen and/or diclofenac. The literature was systematically reviewed in accordance with the
Valentina Manzo et al.
Talanta, 128, 486-492 (2014-07-26)
In this study, six non-steroidal anti-inflammatory drugs (NSAIDs) were extracted from water samples using the rotating-disk sorptive extraction (RDSE) technique. The extraction disk device contains a central cavity that allows for the incorporation of a powdered sorbent phase (Oasis™ HLB).
Francesco Cilurzo et al.
Drug development and industrial pharmacy, 41(2), 183-189 (2013-10-30)
Abstract This work aims to establish if the assays recently introduced by EMA (Guideline on quality of transdermal patches-draft) and USP (Specific tests for transdermal delivery systems) to characterize transdermal patches (TP) are suitable for medicated plasters (MP). Six approved
M S Diniz et al.
The Science of the total environment, 505, 282-289 (2014-12-03)
The occurrence of pharmaceutical compounds in wastewater treatment plants and surface waters has been detected worldwide, constituting a potential risk for aquatic ecosystems. Adult zebrafish, of both sexes, were exposed to three common pharmaceutical compounds (atenolol, ketoprofen and diclofenac) and
Silvia Rocchi et al.
Journal of chromatography. A, 1381, 149-159 (2015-01-24)
A novel sub-2 μm chiral stationary phase (CSP) was prepared immobilizing vancomycin onto 1.8 μm diol hydride-based silica particles. The CSP was packed into fused silica capillaries of 75 μm i.d. with a length of 11 cm and evaluated by
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
Simultaneous HPLC determination of ketoprofen and its degradation products in the presence of preservatives in pharmaceuticals
Dvorak J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(3), 625-629 (2004)
Jodie Barden et al.
The Cochrane database of systematic reviews, (4)(4), CD007355-CD007355 (2009-10-13)
Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions. Dexketoprofen is the (S)-enantiomer, which is believed to confer analgesia. Theoretically dexketoprofen is expected to provide equivalent analgesia to ketoprofen at half the dose
Yun Li et al.
Journal of chromatography. A, 1392, 28-36 (2015-03-22)
A new dendrimer-functionalized mesoporous silica material based on large-pore 3D cubic Korea Advanced Institute of Science and Technology-6 (KIT-6) was synthesized by the growing of dendritic branches inside the mesopores of aminopropyl functionalized KIT-6. Detailed physical characterizations using transmission electron
S Coaccioli
European review for medical and pharmacological sciences, 15(8), 943-949 (2011-08-19)
Ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), possesses analgesic, antipyretic and anti-inflammatory properties. Oral KP is widely used in musculoskeletal pain and inflammation in muscles and joints, including arthritis pain, osteoarthritis, stiffness of the joints, soft tissue rheumatism, and sports
Linda A Felton et al.
AAPS PharmSciTech, 15(4), 872-881 (2014-04-11)
The objective of this research was to investigate physicochemical properties of an active pharmaceutical ingredient (API) that influence cyclodextrin complexation through experimental and computational studies. Native β-cyclodextrin (B-CD) and two hydroxypropyl derivatives were first evaluated by conventional phase solubility experiments
Małgorzata Maciążek-Jurczyk
Pharmacological reports : PR, 66(5), 727-731 (2014-08-26)
A combination of phenylbutazone (PBZ) and ketoprofen (KP) is popular in therapy of rheumatoid arthritis (RA) but could be unsafe due to the uncontrolled growth of toxicity. Quenching fluorescence of serum albumin in the presence of the both drugs has
Cheong Hoon Lee et al.
Talanta, 129, 552-559 (2014-08-17)
Because of the high stability and potential toxic effects of non-steroidal anti-inflammatory drugs (NSAIDs), it is important to closely monitor their concentrations in the environment using a sensitive analytical method. In this study, a simple, rapid, efficient, and sensitive analytical
Ramesh Mullangi et al.
Biomedical chromatography : BMC, 17(7), 423-434 (2003-11-05)
Today, a heightened awareness of the applicability of enantiomers in medicine and clinical practice has been gene-rated due to the continuous evolvement of the field of chirality. In this context, this article provides a review of separation of ketoprofen, an
Lizelle T Fox et al.
The Journal of pharmacy and pharmacology, 67(1), 96-106 (2014-09-10)
The aim of this study was to investigate the in-vitro permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox using ketoprofen as a marker compound. The permeation studies were conducted across excised
Julia Martín et al.
The Science of the total environment, 503-504, 97-104 (2014-06-10)
Sewage sludge disposal onto lands has been stabilized previously but still many pollutants are not efficiently removed. Special interest has been focused on pharmaceutical compounds due to their potential ecotoxicological effects. Nowadays, there is scarce information about their occurrence in
Magdalena Gaweł et al.
Pharmacological reports : PR, 66(5), 862-866 (2014-08-26)
The previous study indicated the enhancement of the anti-inflammatory effect of ketoprofen by acute and sub chronic administration of zinc hydroaspartate. The present study examined anti-inflammatory, anti-ulcerogenic and analgesic activity induced by chronic (14 days) administration of ZHA (30 mg/kg
Mei-Quan Cai et al.
Environmental science and pollution research international, 22(3), 1854-1867 (2014-09-10)
A simultaneous determination method of 14 multi-class pharmaceuticals using solid-phase extraction (SPE) followed by high-performance liquid chromatography-tandem mass spectrometer (HPLC-MS/MS) was established to measure the occurrence and distribution of these pharmaceuticals in tap water and a drinking water treatment plant
B Milpied-Homsi
Presse medicale (Paris, France : 1983), 30(12), 605-609 (2001-04-25)
A COMMON OBSERVATION: Ketoprofene gels, widely used to treat benign conditions, can provoke local intolerance. The most commonly reported clinical features include eczema, sometimes severe acute contact photoallergy that often spread beyond the site of application and may even lead
[Treatment of back pain (ketoprofen and other methods)].
I V Damulin
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 114(2), 81-86 (2014-04-15)
Işık Ozgüney et al.
European journal of drug metabolism and pharmacokinetics, 39(4), 283-291 (2013-10-08)
The main objective of this study was to investigate the release and pharmacokinetic profiles of ketoprofen (KP) from developed thermosensitive and mucoadhesive liquid suppositories. Thermosensitive liquid suppositories were prepared using KP, poloxamer 407 (P 407), poloxamer 188 (P 188) and
Valentina Manzo et al.
Journal of chromatography. A, 1368, 64-69 (2014-12-03)
A novel automatic sorptive microextraction approach combining sequential injection-based programmable flow with rotating disk sorptive extraction (RDSE) is proposed for the clean-up and concentration of low polarity organic species in urine samples. Non-steroidal anti-inflammatory drugs (NSAIDs), namely, ketoprofen, naproxen, diclofenac
Marco Pistolozzi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968, 69-78 (2014-01-30)
A series of novel tocainide analogues were characterized for their HSA and RSA binding, by using high-performance liquid affinity chromatography (HPLAC) and circular dichroism (CD). In this HPLAC study, HSA and RSA were covalently immobilized to the silica matrix of
H R Schumacher
Clinical therapeutics, 16(2), 145-159 (1994-03-01)
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid family with demonstrated efficacy in the treatment of rheumatoid arthritis and osteoarthritis; a distinguished safety profile; and good tolerability. This report describes a new extended-release formulation that maintains therapeutic
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