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Pedro Elias Marques et al.
Hepatology (Baltimore, Md.), 61(1), 348-360 (2014-05-16)
Drug-induced liver injury (DILI) is an important cause of acute liver failure, with limited therapeutic options. During DILI, oncotic necrosis with concomitant release and recognition of intracellular content amplifies liver inflammation and injury. Among these molecules, self-DNA has been widely
Xiaobin Xu et al.
Advanced materials (Deerfield Beach, Fla.), 24(40), 5457-5463 (2012-08-14)
Surface enhanced Raman scattering (SERS) is sensitive enough for single-molecule biochemical detection, but it is extremely difficult to obtain a large number of SERS hotspots for sensitive and reproducible detection. It is even more challenging to assemble the hotspots at
Liyun Ma et al.
Journal of chromatography. A, 1376, 64-73 (2014-12-22)
Cucurbit[7]uril (CB7), one host macromolecule, possesses a hydrophobic inner cavity and two identical hydrophilic carbonyl fringe portals, thus interacting with a variety of guest molecules through hydrophobic, hydrogen bonding and ion-dipole interactions. These characteristics make CB7 a good candidate as
Shengjie Li et al.
The journal of trauma and acute care surgery, 79(1), 78-84 (2015-06-20)
Traumatic brain injury (TBI) confers a high risk of venous thrombosis, but early prevention with heparinoids is often withheld, fearing cerebral hematoma expansion. Yet, studies have shown heparinoids not only to be safe but also to limit brain edema and
Dirk Rosentreter et al.
Shock (Augusta, Ga.), 44(1), 72-76 (2015-05-27)
Programmed necrosis (necroptosis), a newly discovered form of cell death, is mediated by receptor-interacting protein 1 (RIP1) and plays a pivotal role after myocardial, renal, and cerebral ischemia-reperfusion (I/R). The relevance of necroptosis in the postischemic liver remains, however, unclear.
H B Li et al.
Nanoscale, 4(16), 5082-5091 (2012-07-11)
We have developed simple and green electrochemistry to synthesize Ag nanostructures with high purity, good crystallinity and smooth surface for applications as super-SERS (surface-enhanced Raman scattering), SERS-active substrates and with highly effective antimicrobial activities. This synthesis takes place in a
Designing distance dependent SERS assay for monitoring photothermal antibacterial activity response.
Sadia Afrin Khan et al.
Chemical communications (Cambridge, England), 48(90), 11091-11093 (2012-10-11)
This communication reports, for the first time, the design of distance dependent SERS assay for monitoring the photothermal antibacterial activity process.
Jin-Yan Liu et al.
Research in microbiology, 166(3), 153-161 (2015-03-10)
This study was undertaken to characterize the mechanism(s) of azole resistance in clinical isolates of Candida albicans collected in Shanghai, China, focusing on the role of efflux pumps, target enzymes of fluconazole (Erg11), respiratory status and the ergosterol biosynthetic pathway.
Sirajul Haq et al.
Journal of photochemistry and photobiology. B, Biology, 186, 116-124 (2018-07-24)
This paper reports the synthesis of silver oxide (Ag2O) and moxifloxacin functionalized silver oxide (M-Ag2O) nanoparticles for photocatalytic and antimicrobial activity. The Ag2O nanoparticles were synthesized by using 2 dimethyl amino ethanol as reducing agent. The BET surface area measured
Seido Yarimitsu et al.
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 229(7), 506-514 (2015-06-04)
Surface modification by grafting of biocompatible phospholipid polymer onto the surface of artificial joint material has been proposed to reduce the risk of aseptic loosening and improve the durability. Poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted cross-linked polyethylene (CLPE) has shown promising results for
Esther Jiménez et al.
MicrobiologyOpen, 3(6), 937-949 (2014-10-23)
Bile is a biological fluid synthesized in the liver, stored and concentrated in the gall bladder (interdigestive), and released into the duodenum after food intake. The microbial populations of different parts of mammal's gastrointestinal tract (stomach, small and large intestine)
Suvimol Surassmo et al.
Colloids and surfaces. B, Biointerfaces, 130, 229-236 (2015-05-06)
Mucoadhesive poly (lactic-co-glycolic acid) (PLGA) nanoparticles having a modified shell-matrix derived from polyvinyl alcohol (PVA) and Carbopol (CP), a biodegradable polymer coating, to improve the adhesion and cell transfection properties were developed. The optimum formulations utilized a CP concentration in
S R Kavitha et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 133, 472-479 (2014-06-29)
Silver nanoparticles (Ag NPs) of different sizes from 7nm to 22nm have been prepared by simple Dirk and Charles chemical method and characterized using UV-vis spectroscopy and high resolution transmission electron microscopy (HRTEM). Fluorescence quenching of 1,4-dimethoxy-2,3-dimethylanthracene-9,10-dione (DMDMAD) by silver
Kinetic Analysis of Rhodamines Efflux Mediated by the Multidrug Resistance Protein (MRP1)
Chantarawan S
Biophysical Journal, 85(3) (2003)
Ljudmila S Khailova et al.
Biochimica et biophysica acta, 1837(10), 1739-1747 (2014-07-20)
Limited uncoupling of oxidative phosphorylation is known to be beneficial in various laboratory models of diseases. The search for cationic uncouplers is promising as their protonophorous effect is self-limiting because these uncouplers lower membrane potential which is the driving force
Jing Chen et al.
Lab on a chip, 12(17), 3096-3102 (2012-06-29)
We demonstrate that silver nanorod (AgNR) array substrates can be used for on-chip separation and detection of chemical mixtures by combining ultra-thin layer chromatography (UTLC) and surface enhanced Raman spectroscopy (SERS). The UTLC-SERS plate consists of an AgNR array fabricated
Hweon Park et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(3), 837-848 (2014-11-19)
Organization and functions of the nucleolus is maintained by mobilities and interactions of nucleolar factors. Because the nucleolus is a densely packed structure, molecular crowding effects determined by the molecular concentrations and mobilities in the nucleolus should also be important
Ellen J Lee et al.
Arthritis research & therapy, 17, 218-218 (2015-08-20)
Systemic rheumatic conditions are often accompanied by intraocular inflammatory disease (termed uveitis). Despite the frequent manifestation of uveitis with arthritis, very little is understood of the underlying mechanisms that mediate the eye's susceptibility to disease. The genetically susceptible SKG mouse
Fabrizio Anella et al.
Life (Basel, Switzerland), 4(4), 929-943 (2014-12-17)
The "RNA world" and the "Lipid world" theories for the origin of cellular life are often considered incompatible due to the differences in the environmental conditions at which they can emerge. One obstacle resides in the conflicting requirements for divalent
Christian Knierim et al.
Macromolecular bioscience, 15(8), 1052-1059 (2015-04-08)
Herein, we report on composite materials of biologically active microorganisms placed in a synthetic polymer matrix. These so-called "living composites" were utilized for gold sequestration (Micrococcus luteus) and bioremediation of nitrite (Nitrobacter winogradskyi) to demonstrate functionality. For the preparation of
Ping Wu et al.
Analytical chemistry, 84(18), 7692-7699 (2012-08-29)
The aptamer (S2.2)-guided Ag-Au nanostructures (aptamer-Ag-Au) have been synthesized by photoreduction and validated by ultraviolet-visible light (UV-vis) spectra and transmission electron microscopy (TEM) images. Differential interference contrast (DIC), fluorescence, and TEM images, and surface-enhanced Raman scattering (SERS) spectra indicated that
Weirong Fang et al.
Molecular neurobiology, 52(1), 162-175 (2014-08-17)
Following ischemic stroke, blood-brain barrier (BBB) is disrupted and is further aggravated with the corresponding incidence of hyperlipidemia. BBB breakdown promotes inflammation infiltration into the brain, which exacerbates cerebral ischemic injury as a result. Here, we report that 10-O-(N,N-dimethylaminoethyl)-ginkgolide B
Impact of pore size on the vascularization and
osseointegration of ceramic bone substitutes in vivo
osseointegration of ceramic bone substitutes in vivo
Frank M. Klenke
Journal of Biomedical Materials Research (2007)
Jean-Philippe Desilles et al.
Stroke, 46(11), 3241-3248 (2015-10-08)
Downstream microvascular thrombosis (DMT) is known to be a contributing factor to incomplete reperfusion in acute ischemic stroke. The aim of this study was to determine the timing of DMT with intravital imaging and to test the hypothesis that intravenous
Kirsten Buschmann et al.
BMC immunology, 15, 53-53 (2014-11-28)
Insufficient leukocyte recruitment may be one reason for the high incidence of life-threatening infections in preterm infants. Since the receptor of advanced glycation end products (RAGE) is a known leukocyte adhesion molecule and highly expressed during early development, we asked
Nidhi Puri et al.
European journal of medicinal chemistry, 45(11), 4813-4826 (2010-08-27)
In this study, we have explored the structure activity relationships of substrates of two major, promiscuous, multidrug transporters of an opportunistic human pathogen Candida albicans namely, CaCdr1p and CaMdr1p. To differentiate between substrates and non-substrates, the susceptibilities of the Saccharomyces
Şefik E Erdener et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 41(2), 236-252 (2020-04-03)
Ever since the introduction of thrombolysis and the subsequent expansion of endovascular treatments for acute ischemic stroke, it remains to be identified why the actual outcomes are less favorable despite recanalization. Here, by high spatio-temporal resolution imaging of capillary circulation
Kenji Katayama et al.
Chemical communications (Cambridge, England), 48(59), 7368-7370 (2012-06-21)
A new type of photocatalytic reactor was developed. Capillaries coated on the inside with photocatalytic materials induced an effective photocatalytic reaction by pulling up a solution under the action of capillary forces; no electric pump was required for the replacement
Kaiyang Cai et al.
Forensic science international, 226(1-3), 240-243 (2013-02-23)
A new method based on the use of highly fluorescent water-soluble cadmium telluride (CdTe) quantum dots (QDs) capped with mercaptosuccinic acid (MSA) was explored to develop latent fingerprints. After optimized the effectiveness of QDs method contains pH value and developing
Herman S Mansur et al.
Materials science & engineering. C, Materials for biological applications, 52, 61-71 (2015-05-09)
Cancer remains one of the world's most devastating diseases with millions of fatalities and new cases every year. In this work, we attempted to develop a facile "enzyme-free" fluoroimmunoassay based on the novel nanoconjugates composed of CdS quantum dots (QDs)
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