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RAB0117
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关键词:'RAB0117'
显示 1-30 #N/A 142 条结果 关于 "RAB0117" 范围 论文
Cid Almeida de Lima et al.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 40(3), 401-405 (2019-09-04)
The aim of this study was to evaluate cytokine levels (IL-2, IL-8, TNF-α, IL-5, IL-6 and IL-10) in the peritoneal fluid in non-neoplastic tumours, benign ovarian neoplasms and malignant ovarian neoplasms. Peritoneal fluid or ascites was collected from 117 patients
DHA Attenuates Hypoxia/Reoxygenation Injury by Activating SSeCKS in Human Cerebrovascular Pericytes.
Yanli Yu et al.
Neurochemical research, 45(2), 310-321 (2019-11-30)
Docosahexaenoic acid (DHA) can alleviate cerebral ischemia/reperfusion injury by reducing blood-brain barrier permeability and maintaining its integrity, accompanied by an increased Ang-1/Ang-2 ratio; however, the underlying mechanisms of these effects remain unclear. Src-suppressed C kinase substrates (SSeCKS), a substrate of
Seiji Saito et al.
Protein science : a publication of the Protein Society, 29(5), 1186-1195 (2020-03-07)
IgG2 subclass antibodies have unique properties that include low effector function and a rigid hinge region. Although some IgG2 subclasses have been clinically tested and approved for therapeutic use, they have a higher propensity than IgG1 for aggregation, which can
Jiraphorn Issara-Amphorn et al.
Journal of innate immunity, 12(6), 461-479 (2020-09-15)
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the
Pradeep K Kudipudi et al.
International journal of molecular sciences, 20(24) (2019-12-15)
Transforming growth factor-βs (TGF-βs) signal after binding to the TGF-β receptors TβRI and TβRII. Recently, however, betaglycan (BG) was identified as an important co-receptor, especially for TGF-β2. Both proteins are involved in several testicular functions. Thus, we analyzed the importance
Juan I Bastón et al.
The Journal of pathology, 234(3), 329-337 (2014-07-01)
Endometriosis is characterized by the presence of endometrial tissue outside the uterus that causes severe pelvic pain and infertility in women of reproductive age. Although not completely understood, the pathophysiology of the disease involves chronic dysregulation of inflammatory and vascular
Andreas Kupz et al.
Scientific reports, 10(1), 13115-13115 (2020-08-06)
Toxoplasmic encephalitis is an AIDS-defining condition. The decline of IFN-γ-producing CD4+ T cells in AIDS is a major contributing factor in reactivation of quiescent Toxoplasma gondii to an actively replicating stage of infection. Hence, it is important to characterize CD4-independent
Wenjing Zhu et al.
Peptides, 135, 170423-170423 (2020-10-22)
Advanced stage of prostate cancer cells preferentially metastasizes to varying bones of prostate cancer patients, resulting in incurable disease with poor prognosis and limited therapeutical treatment options. Calcitonin gene-related peptide (CGRP), a neuropeptide produced by prostate gland, is known to
Jeong-Eun Choi et al.
The Journal of nutritional biochemistry, 84, 108417-108417 (2020-07-07)
Stress and ovarian hormone fluctuation are risk factors for postpartum depression (PPD). Previous studies suggested antidepressant-like effects of n-3 polyunsaturated fatty acids (PUFA), but their effect on dam animal with additional stress were not clear. The purpose of the present
Sima Nazarpour et al.
Biological trace element research, 194(2), 348-359 (2019-07-31)
Iodine is essential for the production of thyroid hormones, and its deficiency during pregnancy may be associated with poor obstetric outcomes. The aim of this study was to investigate the relationship between maternal iodine statuses with pregnancy outcomes among pregnant
Emily M Yura et al.
Urology, 146, 242-247 (2020-09-06)
To determine the ability of testosterone and estrogen to reverse urethral hypovascularity secondary to hypogonadism, we analyzed the effects of testosterone and estrogen supplementation on castrated Sprague Dawley rats. Twenty four Sprague-Dawley rats were divided into 4 groups: (1) non-castrate
Nikolce Gjorevski et al.
Lab on a chip, 20(18), 3365-3374 (2020-08-08)
The multiphasic etiology of tissue inflammation and the fundamental immunological differences between species render inflammatory pathologies difficult to recapitulate in animal models, and account for the paucity of therapies that are successfully translated from rodents to humans. Here, we present
Federica Battaglia et al.
Animals : an open access journal from MDPI, 10(9) (2020-08-30)
In human medicine, procalcitonin (PCT), the precursor of calcitonin, is used for the rapid identification of the origin and severity of sepsis. In veterinary medicine, PCT has been studied in horses, cattle, and dogs, but the use of PCT in
Carmen L Charlton et al.
Journal of clinical microbiology, 58(10) (2020-07-16)
Coronavirus disease (COVID) serological tests are essential to determine the overall seroprevalence of a population and to facilitate exposure estimates within that population. We performed a head-to-head assessment of enzyme immunoassays (EIAs) and point-of-care lateral flow assays (POCTs) to detect
Anat Chemerinski et al.
Journal of cancer survivorship : research and practice, 14(5), 607-613 (2020-04-24)
This study sought to evaluate the prevalence of menopausal symptoms in a population of reproductive-aged women remote from cancer therapy compared with a group of healthy similar-aged controls and with a cohort of late reproductive-aged (LR) controls. Participants were assessed
Xinyu Zhuang et al.
Vaccines, 8(1) (2020-03-14)
The design of the mRNA vaccine involves the selection of in vitro transcription (IVT) systems and nonviral delivery vectors. This study aimed to verify the effect of 5' and 3' untranslated region (UTR) sequences on the translation efficiency of mRNA.
Eun-Hye Hong et al.
Cancer letters, 493, 102-112 (2020-08-19)
Toll-like receptor (TLR)3 and TLR7 are important for stimulating plasmacytoid dendritic cells (pDCs), which secrete type I interferon. Mice deficient for TLR3 and TLR7 (TLR3-/-TLR7-/-) reportedly exhibit deteriorated colitis because of impaired pDCs. However, the role of pDCs in tumorigenesis-associated
Miralireza Takyar et al.
Thyroid : official journal of the American Thyroid Association, 30(8), 1186-1192 (2020-03-12)
Introduction: Autoimmune thyroid disease is the most common autoimmune disorder. Evidence regarding causes of the high prevalence and incidence
Shaghayegh Baradaran Ghavami et al.
International journal of molecular sciences, 21(17) (2020-09-03)
In inflammatory bowel diseases (IBD), the therapeutic benefit and mucosal healing from specific probiotics may relate to the modulation of dendritic cells (DCs). Herein, we assessed the immunomodulatory effects of four probiotic strains including Lactobacillus salivarius, Bifidobacterium bifidum, Bacillus coagulans
Li Ma et al.
Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 1407-1415 (2020-05-20)
Glucagon-like peptide-1 (GLP-1) is secreted from the intestinal L-cells to stimulate insulin secretion in the blood glucose control. Our previous study indicates that Sennoside A (SA) can increase the plasma GLP-1 level in a mouse model of type 2 diabetes. However
Ik-Hwan Han et al.
PLoS neglected tropical diseases, 14(3), e0008126-e0008126 (2020-03-21)
Trichomonas vaginalis (Tv), a protozoan parasite causing sexually-transmitted disease, has been detected in tissue of prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer (PCa). IL-6, a mediator of chronic inflammation, induces the progression of prostate cancer, and influences the polarization
Ji Hun Suh et al.
Journal of clinical medicine, 9(2) (2020-02-23)
Colorectal cancer (CRC) is one of the leading causes of world cancer deaths. To improve the survival rate of CRC, diagnosis and post-operative monitoring is necessary. Currently, biomarkers are used for CRC diagnosis and prognosis. However, these biomarkers have limitations
Heliang Liu et al.
Mediators of inflammation, 2020, 2683753-2683753 (2020-05-01)
Silicosis is a devastating disease caused by inhalation of silica dust that leads to inflammatory cascade and then scarring of the lung tissue. Increasing evidences indicate that soluble receptor for advanced glycation end products (sRAGE) is involved in inflammatory diseases.
Mi Ran Kim et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 7941391-7941391 (2020-07-01)
Red clover and hops are already known for their alternative menopausal therapies; however, their combination has not yet been studied. This study aimed to evaluate the efficacy of the combination of red clover and hops extract (RHEC) for treating menopausal
Laura David et al.
Biotechnology and bioengineering, 117(4), 1024-1036 (2020-01-14)
Continuous processing is the future production method for monoclonal antibodies (mAbs). A fully continuous, fully automated downstream process based on disposable equipment was developed and implemented inside the MoBiDiK pilot plant. However, a study evaluating the comparability between batch and
Ahmad H Alghadir et al.
Clinical interventions in aging, 15, 1271-1283 (2020-08-22)
Poor daily life physical activities among older people were related to depressive mood especially memory loss. In addition to that, the change in physical ability is significantly associated with the score of depression among older age. The present study aimed
Barbara Choromańska et al.
Journal of clinical medicine, 9(4) (2020-04-05)
This is the first study to evaluate both the antioxidant barrier, glutathione metabolism, and oxidative damage to proteins and lipids in morbidly obese patients undergoing bariatric treatment. The study included 65 patients with class 3 obesity divided into two subgroups:
Lucia M Moreira et al.
Nature, 587(7834), 460-465 (2020-11-06)
Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality and morbidity, and particularly to the risk of stroke in humans1. Atrial-tissue fibrosis is a central pathophysiological feature of atrial fibrillation that also hampers its treatment; the underlying molecular
Xiaoping Luo et al.
Pharmaceutical biology, 58(1), 886-897 (2020-09-04)
Obacunone, a limonoid abundantly found in Citrus fruits, exhibits a variety of bioactivities. To investigate the effects of obacunone on a colorectal cancer (CRC) mouse model, and clarify its potential molecular mechanisms. The male Balb/c mice were induced with azoxymethane
Alfred K Njamnshi et al.
The American journal of tropical medicine and hygiene, 103(6), 2244-2252 (2020-10-21)
Human African trypanosomiasis (HAT) remains a serious public health problem with diagnostic and treatment challenges in many African countries. The absence of a gold-standard biomarker has been a major difficulty for accurate disease staging and treatment follow-up. We therefore attempted
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