CN
Search Within
S3003
应用筛选条件
关键词:'S3003'
显示 1-27 共 27 条结果 关于 "S3003" 范围 论文
Comments on Vennila and Pugalendi. Vennila L, Pugalendi KV. Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. Redox Rep 2010; 15: 36-42.
Srinivasan Periasamy et al.
Redox report : communications in free radical research, 15(6), 288-289 (2011-01-07)
Jinliang Yang et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 12(2), 323-329 (2012-10-11)
A benzodioxole derivative, 4-(2-(benzodioxol-5-yloxy)ethoxy)benzophenone (BPC2BDO), based on 4-hydroxybenzophenone and sesamol was synthesized, and used as a one-component Type II photoinitiator. The structure of BPC2BDO was characterized by elementary analysis, APCI-MS, (1)H NMR, and (13)C NMR. The rate of decomposition (R(d))
Vandita Kakkar et al.
Rejuvenation research, 14(6), 597-604 (2011-10-08)
The physicochemical nature of sesamol (logP 1.29; solubility 38.8 mg/mL) substantially enhances its tissue distribution, minimizing its brain delivery. Sesamol-loaded solid lipid nanoparticles (S-SLNs) with an average particle size of 122 nm and an entrapment efficiency of 75.9 ± 2.91% were developed. Biochemical and
Zhigang Liu et al.
Food chemistry, 141(1), 289-296 (2013-06-19)
Sesamol, a nutritional antioxidant phenolic compound present in sesame seed, has a potential therapeutic molecule effect against cancers. In this study, the interaction between sesamol and DNA was investigated by employing ultraviolet/visible (UV/Vis), fluorescence, circular dichroism (CD), Fourier transform infrared
Baldeep Kumar et al.
Psychopharmacology, 214(4), 819-828 (2010-11-26)
A complex relationship exists among stressful situations, body's reaction to stress, and the onset of clinical depression. Chronic unpredictable stressors can produce a situation similar to clinical depression, and such animal models can be used for the preclinical evaluation of
Tian Yuan et al.
Journal of agricultural and food chemistry, 67(22), 6190-6201 (2019-05-24)
Sesamol, an antioxidant lignan from sesame oil, possesses neuroprotective bioactivities. The present work was aimed to elucidate the systemic protective effects of sesamol on cognitive deficits and to determine the possible link between gut and brain. Wildtype and ApoE-/- mice
Annia Galano et al.
The journal of physical chemistry. B, 115(44), 13101-13109 (2011-10-05)
Reactions of sesamol with different free radicals, in lipid and aqueous media, have been studied at the M05-2X/6-311+G(d,p) level of theory in conjunction with the SMD continuum model. Different mechanisms of reaction have been considered as well as polar and
P-Y Chu et al.
Human & experimental toxicology, 31(4), 397-404 (2011-11-15)
Acute pancreatitis is a potentially fatal disease with no known cure. The initial events in acute pancreatitis may occur within the acinar cells. We examined the effect of sesamol on (i) a cerulein-induced pancreatic acinar cancer cell line, AR42J, and
Ying-Hui Chen et al.
Journal of agricultural and food chemistry, 59(18), 9885-9891 (2011-08-26)
Sesamol, a pure compound of sesame, has been reported to have antitumor effects. In the present study, the apoptotic and steroidogenic effects of sesamol on MA-10 cells, a mouse Leydig tumor cell line, was investigated by morphological observations, cell viability
Lakshmanan Vennila et al.
Archives of pharmacal research, 35(8), 1465-1470 (2012-09-04)
Myocardial infarction is the leading cause of death all over the world. Sesamol is a potent phenolic antioxidant contained only in processed sesame oil and possesses potent chemopreventive, antimutagenic, antihepatotoxic and antioxidation properties. This study was undertaken to investigate the
Aya Fujimoto et al.
Toxicology in vitro : an international journal published in association with BIBRA, 24(6), 1720-1726 (2010-06-01)
Many effects of sesamol, an antioxidative constituent of sesame oil, have been reported for human health benefits due to its antioxidative action. However, we recently isolated two cytotoxic products, trimer and tetramer of sesamol, from oxidation of sesamol by an
K Mishra et al.
Radiation research, 176(5), 613-623 (2011-09-09)
Protection against radiation-induced DNA strand breaks is an important aspect in the design and development of a radioprotector. In this study, the radioprotective efficacy of sesamol, a natural antioxidant, was investigated in aqueous solution of plasmid DNA (pBR322) and compared
Rekha R Shenoy et al.
Journal of ethnopharmacology, 133(2), 608-612 (2010-11-03)
ETHNO-PHARMACOLOGICAL RELEVANCE: The seeds of Sesamum indicum Linn. (Pedaliaceae) has been used traditionally for the treatment of wounds in Buldhana district of Maharashtra state. Sesamol is the main anti-oxidative constituent contained mainly in the processed sesame seed oil which has
C Mahendra Kumar et al.
Biochimie, 93(3), 562-569 (2010-12-15)
Sesamin, sesamolin (lignans) and sesamol--from sesame seed (Sesamum indicum L.)--are known for their health promoting properties. We examined the inhibition effect of sesamol, a phenolic degradation product of sesamolin, on the key enzyme in melanin synthesis, viz. tyrosinase, in vitro.
Srinivasan Periasamy et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(3-4), 273-280 (2011-04-08)
The protective role of sesamol and its possible action against isoproterenol-induced myocardial injury and infarction is unknown. We tested the hypothesis that sesamol's protection against myocardial infarction is associated with the inhibition of matrix metalloproteinase (MMP)-2 and MMP-9. Four groups
Shubham Misra et al.
European journal of pharmacology, 659(2-3), 177-186 (2011-04-06)
Alzheimer's disease is a neurodegenerative disorder characterized by progressive cognitive decline and widespread loss of neurons and their synapses in the cerebral cortex and hippocampus. Increasing evidence indicates that factors such as oxidative-nitrergic stress, glutathione depletion, impaired protein metabolism and
Zhekang Ying et al.
Arteriosclerosis, thrombosis, and vascular biology, 31(3), 536-542 (2010-12-25)
Sesamol, a phenolic component of lignans, has been previously shown to reduce lipopolysaccharide-induced oxidative stress and upregulate phosphatidylinositol 3-kinase/Akt/endothelial nitric oxide synthase pathways. In the present study, we synthesized a modified form of sesamol (INV-403) to enhance its properties and
Gopakumar Gopinathan Nair et al.
Cancer biotherapy & radiopharmaceuticals, 25(6), 629-635 (2011-01-06)
Sesamol (SM), a nutritional phenolic antioxidant compound present in sesame seeds, protected pBR 322 DNA from gamma radiation-induced damages. SM prevented gamma radiation-induced degradation of covalently closed circular form of plasmid DNA in a concentration-dependent manner. Also SM protected cellular
Yung-Chang Lu et al.
Journal of agricultural and food chemistry, 59(9), 4969-4978 (2011-03-25)
Overexpression of matrix metalloproteinases (MMPs) is a major pathological factor causing cartilage destruction in osteoarthritis (OA). This study aimed to investigate the effects and mechanisms of sesamol on expression of MMPs in activated chondrosarcoma cells. Sesamol significantly attenuated TNF-α- and
Ashok Kumar Sharma et al.
The Journal of nutritional biochemistry, 23(11), 1482-1489 (2012-03-09)
Increased oxidative stress and inflammation in obesity are the central and causal components in the pathogenesis and progression of cardiometabolic syndrome (CMetS). The aim of the study was to determine the potential role of sesamol (a natural powerful antioxidant and
Soheila Kashanian et al.
Molecular biology reports, 40(2), 1173-1179 (2012-10-17)
The interaction of native calf thymus DNA (CT-DNA) with sesamol (3,4-methylenedioxyphenol) in Tris-HCl buffer at neutral pH 7.4 was monitored by absorption spectrophotometry, viscometry and spectrofluorometry. It is found that sesamol molecules could interact with DNA outside and/or groove binding
S Ramachandran et al.
Archives of dermatological research, 302(10), 733-744 (2010-08-11)
The exposure of cells to ultraviolet B radiation (UVB) can induce the production of reactive oxygen species (ROS) which damage cellular components. Free radical scavengers and antioxidants can interfere with the production of ROS. We studied cytotoxicity, intracellular ROS levels
Jesús F Arteaga et al.
Molecules (Basel, Switzerland), 17(5), 5126-5138 (2012-05-05)
Antioxidant activity of a number of small (low molecular weight) natural compounds found in spices, condiments or drugs (gallic acid, sesamol, eugenol, thymol, carvacrol, vanillin, salicylaldehyde, limonene, geraniol, 4-hexylresorcinol, etc.) has been evaluated using electrochemical and DPPH• radical scavenging measurements.
Srinivasan Periasamy et al.
Cell biochemistry and biophysics, 61(2), 327-336 (2011-06-18)
We investigated the therapeutic effect of sesamol against monocrotaline-induced sinusoidal obstruction syndrome (SOS) in rats. Male Sprague-Dawley rats were gavaged with a single dose of monocrotaline (90 mg/kg) to induce SOS. Sesamol (5, 10, 20, and 40 mg/kg) was subcutaneously
Chao-Chien Chang et al.
Journal of biomedical science, 18, 93-93 (2011-12-16)
Platelet activation is relevant to a variety of coronary heart diseases. Our previous studies revealed that sesamol possesses potent antiplatelet activity through increasing cyclic AMP formation. Although platelets are anucleated cells, they also express the transcription factor, NF-κB, that may
Chifumi Kinugasa et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 22(6), 526-531 (2011-05-18)
Prevention of arterial thrombotic diseases has a high priority in developed countries. An inappropriate diet is known to enhance the risks for acute thrombotic events, and nutritional products experimentally shown to be antithrombotic, might contribute beneficial effects. The present study
Victor Raj Mohan Chandrasekaran et al.
Human & experimental toxicology, 30(10), 1609-1615 (2011-01-18)
3,4-Methylenedioxyphenol (sesamol) is effective against acetaminophen-induced liver injury in rats. Whether sesamol's anti-hepatotoxic effect is comparable to that of N-acetylcysteine has never been studied. We investigated the anti-hepatotoxic effects of sesamol and N-acetylcysteine on acetaminophen-induced hepatotoxicity in mice. Equimolar doses
1/1