CN
Search Within
S4751
应用筛选条件
关键词:'S4751'
显示 1-30 共 232 条结果 关于 "S4751" 范围 论文
Anthony Tomlinson et al.
Molecular pharmaceutics, 12(11), 3805-3815 (2015-10-01)
Polysorbate 20 (PS20), a commonly used surfactant in biopharmaceuticals, showed degradation upon long-term (∼18-36 months) storage of two monoclonal antibody (mAb, mAb-A, and mAb-B) drug products at 2-8 °C. The PS20 degradation resulted in the accumulation of free fatty acids
Tae Hwan Kim et al.
Journal of chromatographic science, 53(7), 1100-1106 (2014-12-20)
Chloroacetamide (CAA) is a preservative used in various cosmetic, personal care and household products. Due to the hazard potential for allergic reaction and reproductive toxicity, CAA is being considered a high priority for screening assessment and toxicological re-evaluation. This study
Zulfiqar Ali Mirani et al.
Pakistan journal of pharmaceutical sciences, 26(2), 383-389 (2013-03-05)
In the present study a vancomycin resistant Staphylococcus aureus (S. aureus) (VRSA) (Labeled as CP2) was isolated from the blood of a post-operative cardiac patient is described. It harbors a plasmid which carry vanA gene and exhibited low-level vancomycin resistance
Marie Guhmann et al.
Drug development and industrial pharmacy, 41(4), 540-551 (2014-02-06)
Fast onset of action is prerequisite for acute pain medication. A palatable orodispersible medicine of diclofenac providing rapid analgesic effect should improve patient compliance and treatment. In the present study, diclofenac taste-masked orodispersible tablets (ODTs) with fast release characteristics were
F F de Sousa et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 148, 280-288 (2015-04-25)
This paper reports the temperature-dependent measurements in the C form of stearic acid. Raman scattering, X-ray diffraction, and differential scanning calorimetry measurements were performed at low temperatures. The polarized Raman spectra were measured for temperatures ranging from 8 to 300
P Sanjurjo et al.
Acta paediatrica Scandinavica, 77(2), 202-206 (1988-03-01)
Plasma fatty acids were studied in 20 full-term newborn infants fed human milk and in 17 newborn infants of identical characteristics fed an adapted cow's milk formula. Plasma fatty acids were measured in cord blood and at 7-9 days of
Piret Arukuusk et al.
Biochimica et biophysica acta, 1828(5), 1365-1373 (2013-01-30)
Harnessing of a branched structure is a novel approach in the design of cell-penetrating peptides and it has provided highly efficient transfection reagents for intracellular delivery of nucleic acids. The new stearylated TP10 analogs, NickFects, condense plasmid DNA, splice correcting
Stuart L Cantor et al.
Drug development and industrial pharmacy, 41(7), 1156-1164 (2014-07-08)
The purpose of this research was to develop an orally disintegrating tablet (ODT) dosage form containing taste-masked beads of clindamycin HCl. Several formulation strategies were evaluated and a taste-masked ODT of clindamycin HCl was prepared without the use of a
Armin Saeedi Vahdat et al.
International journal of pharmaceutics, 454(1), 333-343 (2013-07-04)
The mechanical properties of a solid dosage, defined by its granular micro-structure and geometry, play a key role in its dissolution profile and performance. An ultrasonic method for extracting the viscoelastic material properties and granular structure of drug tablet compacts
Gordon Sproul
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 45(4), 427-437 (2015-08-08)
Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino acids, producing phosphate-free amphipathic lipoamino acids and lipopeptides. These
A Olejnik et al.
International journal of cosmetic science, 37(4), 401-407 (2015-02-24)
The aim of this work was to investigate the long-term stability of four emulsions (creams and ointments) developed for carrying hyaluronic acid (HA) for dermal penetration. The stability of obtained formulations was analysed by multiple light scattering and laser diffraction
E Zamora-Rojas et al.
Meat science, 95(3), 503-511 (2013-06-25)
A handheld micro-electro-mechanical system (MEMS) based spectrometer working in the near infrared region (NIR) (1600-2400nm) was evaluated for in-situ and non-destructive prediction of main fatty acids in Iberian pig (IP) carcasses. 110 IP carcasses were measured. Performance of the instrument
Zhanguo Gao et al.
Molecular endocrinology (Baltimore, Md.), 18(8), 2024-2034 (2004-05-15)
Insulin receptor substrate (IRS) has been suggested as a molecular target of free fatty acids (FFAs) for insulin resistance. However, the signaling pathways by which FFAs lead to the inhibition of IRS function remain to be established. In this study
Sindhuri Maddineni et al.
AAPS PharmSciTech, 16(2), 444-454 (2014-11-02)
The objective of the present study was to investigate the effects of processing variables and formulation factors on the characteristics of hot-melt extrudates containing a copolymer (Kollidon® VA 64). Nifedipine was used as a model drug in all of the
Mi Yang et al.
Theriogenology, 148, 68-75 (2020-03-08)
Spermatogonial stem cells (SSCs) are defined as the tissue-specific stem cells in the testes that produce sperm and support life-long spermatogenesis. A culture microenvironment could convert mouse SSCs from unipotent to pluripotent states; however, the underlying mechanism is unclear. NANOG
Tatiana Cucu et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(9), 1406-1415 (2015-07-28)
Sucrose esters (E 473) are emulsifiers used in foods to improve different technological properties. They should conform to the specifications laid down in Commission Regulation No. 231/2012 and be used at amounts not exceeding the maximal ones set by Commission
Meng He et al.
ACS applied materials & interfaces, 5(3), 585-591 (2013-01-08)
A novel, highly hydrophobic cellulose composite film (RCS) with biodegradability was fabricated via solvent-vaporized controllable crystallization of stearic acid in the porous structure of cellulose films (RC). The interface structure and properties of the composite films were investigated with wide-angle
G Hoffmann et al.
Clinical chemistry, 35(4), 587-595 (1989-04-01)
This new method for qualitative and quantitative determination of organic acids, aldehydes, and ketones in biological samples is effective for use with urine, plasma, and amniotic fluid, and it requires no deproteinization. Isolation by batch-wise liquid partition chromatography on silicic
Anastasia Tkacheva et al.
ChemSusChem, 8(16), 2670-2680 (2015-07-23)
Amidation of renewable feedstocks, such as fatty acids, esters, and Chlorella alga based biodiesel, was demonstrated with zeolites and mesoporous materials as catalysts and ethanolamine, alaninol, and leucinol. The last two can be derived from amino acids present in alga.
Oswald Quehenberger et al.
Journal of lipid research, 51(11), 3299-3305 (2010-07-31)
The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a regular part of every patient's blood test
S Sehati et al.
Journal of colloid and interface science, 462, 130-139 (2015-10-11)
In this paper, the degradation of Congo red (CR) as a dye was investigated by a new synthetic photocatalyst. The synthesis was done through the intercalation of CdS in the layers of titanate (K2Ti4O9) by the assistance of ultrasound. The
A M Turpeinen et al.
Arteriosclerosis, thrombosis, and vascular biology, 18(2), 316-322 (1998-03-04)
The effects of stearic acid (C18:0) and trans-fatty acids (trans-FAs) on measures of platelet function and prostacyclin (PGI2) production are poorly understood in humans. In this controlled dietary study, platelet function and endothelial PGI2 production were studied in healthy humans
Yunbao Liu et al.
Journal of natural products, 73(7), 1193-1195 (2010-06-23)
Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple formazan by mitochondrial enzymes. NADPH is the basis of established in vitro cell viability assays. An antioxidant assay
Alfonso Pérez-Gallardo et al.
Journal of food science and technology, 52(9), 5601-5610 (2015-09-08)
There is increased interest in berry fruits due to health benefits, and maintenance of fruit quality for longer periods of time has been a priority. We previously found that starch based coatings applied on raspberries was associated to volatile compounds
S M Grundy
The American journal of clinical nutrition, 60(6 Suppl), 986S-990S (1994-12-01)
Stearic acid is a long-chain saturated fatty acid. However, in contrast with other saturated fatty acids, stearic acid apparently does not raise serum cholesterol concentrations. Studies carried out three decades ago provided strong suggestive evidence that this was the case.
Keisuke Aoshima et al.
PloS one, 8(10), e77715-e77715 (2013-11-10)
Since spermatogonial stem cells (SSCs) are capable of both self-renewal and differentiation to daughter cells for subsequent spermatogenesis, the development of an efficient in vitro culture system is essential for studies related to spermatogenesis. Although the currently available system is
Xiaobing Yang et al.
Bioresource technology, 193, 557-562 (2015-07-15)
Microbial lipids produced by oleaginous yeasts serve as promising alternatives to traditional oils and fats for the production of biodiesel and oleochemicals. To improve its techno-economics, it is pivotal to use wastes and produce high quality lipids of special fatty
Jun-Hyung Park et al.
International journal of pharmaceutics, 491(1-2), 393-401 (2015-07-08)
Photodynamic therapy (PDT) is a promising noninvasive treatment modality for cancer. Photosensitizer and specific wave length of light are the key component of PDT. DH-I-180-3, a second generation photosensitizer, was incorporated into lipid nanoparticle for simultaneous fluorescent imaging and targeting
Shao-Ying Hu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(20), 3052-3055 (2013-01-15)
To prepare the sustained release solid dispersion of tripterine, using HPMC-stearic acid with the intention of improving drug dissolution and controlling drug releases moderate, so that the drug performances lower toxicity. Tripterine sustained release solid dispersions was prepared by the
K Friedauer et al.
Journal of animal physiology and animal nutrition, 99(5), 950-961 (2014-10-30)
Early lactating cows mobilize adipose tissue (AT) to provide energy for milk yield and maintenance and are susceptible to metabolic disorders and impaired immune response. Conjugated linoleic acids (CLA), mainly the trans-10, cis-12 isomer, reduce milk fat synthesis and may
1/8