Merck
CN
Search Within

S8761

应用筛选条件
关键词:'S8761'
显示 31-60 共 114 条结果 关于 "S8761" 范围 论文
Sarah C Power et al.
Scientific reports, 8(1), 17013-17013 (2018-11-20)
Nocturnal mice fed in the middle of the light period exhibit food anticipatory rhythms of behavior and physiology under control of food-entrainable circadian clocks in the brain and body. This is presumed to be adaptive by aligning behavior and physiology
Shin Yamazaki et al.
Methods in enzymology, 393, 288-301 (2005-04-09)
Luminescence reporters have been used successfully in studies of circadian rhythms. Real-time measurements of circadian variations in gene expression were made in living cells, cultured tissues, and whole organisms. Because this technique is relatively easy and continuous noninvasive measurement from
G Christodoulopoulos et al.
The Veterinary record, 172(4), 100-100 (2012-12-27)
'Salivary abomasum disease' is a common syndrome in Greece affecting lambs and kids from three to 17 days of age. In this case series, we present clinical and laboratory findings from 37 affected lambs presented alive and subsequently euthanased for
Xiao-juan Ma et al.
Journal of the science of food and agriculture, 93(13), 3209-3215 (2013-04-05)
Ovalbumin (OVA) is a major allergen in hen egg. During thermal processing, reducing sugars contained in the hen egg white might easily undergo glycation with OVA, but few studies have been conducted on its corresponding immunoreactivity changes. The aim of
C J E Beveridge et al.
The Cochrane database of systematic reviews, (1)(1), CD004864-CD004864 (2006-01-27)
For many years, intravenous sodium bicarbonate has been used to reverse acidosis during newborn resuscitation. However, controversy surrounds its use. Most of the evidence has been derived from studies in animals, adult humans, or in uncontrolled, descriptive experiments. Despite the
Treatment of acidosis in CKD.
Muhammad M Yaqoob
Clinical journal of the American Society of Nephrology : CJASN, 8(3), 342-343 (2013-02-02)
Tânia Fernandes et al.
Biomedicines, 9(8) (2021-08-28)
Alzheimer's disease (AD) is characterized by the accumulation of extracellular plaques composed by amyloid-β (Aβ) and intracellular neurofibrillary tangles of hyperphosphorylated tau. AD-related neurodegenerative mechanisms involve early changes of mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) and impairment of cellular events
Lynda Saber Cherif et al.
International journal of molecular sciences, 20(20) (2019-10-17)
The micronutrients vitamins B9 and B12 act as methyl donors in the one-carbon metabolism involved in transmethylation reactions which critically influence epigenetic mechanisms and gene expression. Both vitamins are essential for proper development, and their deficiency during pregnancy has been
Nimrit Goraya et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(3), 371-381 (2013-02-09)
Current guidelines recommend Na(+)-based alkali for CKD with metabolic acidosis and plasma total CO2 (PTCO2) < 22 mM. Because diets in industrialized societies are typically acid-producing, we compared base-producing fruits and vegetables with oral NaHCO3 (HCO3) regarding the primary outcome
J M Moon et al.
Clinical toxicology (Philadelphia, Pa.), 52(1), 48-53 (2013-12-20)
Despite a widespread use of dicamba herbicide and numerous animal model studies, there had not been studies on acute toxicity of this chemical compound in human subjects following ingestion. Therefore, this study was conducted to investigate clinical characteristics of dicamba
Alessio Innocenti et al.
Bioorganic & medicinal chemistry letters, 15(3), 573-578 (2005-01-25)
A detailed inhibition study of five carbonic anhydrase (CA, EC 4.2.1.1) isozymes with carboxylates including aliphatic (formate, acetate), dicarboxylic (oxalate, malonate), hydroxy/keto acids (l-lactate, l-malate, pyruvate), tricarboxylic (citrate), or aromatic (benzoate, tetrafluorobenzoate) representatives, some of which are important intermediates in
Jeremiah R Brown et al.
JACC. Cardiovascular interventions, 2(11), 1116-1124 (2009-11-21)
We sought to conduct a meta-analysis to compare N-acetylcysteine (NAC) in combination with sodium bicarbonate (NaHCO(3)) for the prevention of contrast-induced acute kidney injury (AKI). Contrast-induced AKI is a serious consequence of cardiac catheterizations and percutaneous coronary interventions (PCI). Despite
Daniela Vullo et al.
Bioorganic & medicinal chemistry letters, 21(12), 3591-3595 (2011-05-17)
Two new β-carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogen Salmonella enterica serovar Typhimurium, stCA 1 and stCA 2, were characterized kinetically. The two enzymes possess appreciable activity as catalysts for the hydration of CO(2) to bicarbonate, with k(cat)
Elizabeth J Scharman et al.
The Annals of pharmacotherapy, 47(1), 90-105 (2013-01-18)
To conduct a systematic literature review to evaluate evidence-based recommendations for the prevention of rhabdomyolysis-associated acute renal failure (ARF). PubMed (1966-December 2012), International Pharmaceutical Abstracts, Science Citation Index, and Cochrane databases (1970-December 2012) were searched. There were no language restrictions.
J Do Valle Bargieri et al.
The Journal of sports medicine and physical fitness, 53(5), 470-476 (2013-08-02)
Decrease in peripheral oxygen delivery may impact exercise performance in athletes with exercise-related arterial oxygen desaturation (ERD). We evaluated whether sodium bicarbonate ingestion would be effective to reduce ERD and what is the consequences upon exercise performance. Seventy highly trained
Nora L Salaberry et al.
Molecular neurobiology, 54(7), 5327-5334 (2016-09-02)
Circadian rhythms are strongly affected by drugs. In rodents, chronic methamphetamine (METH) intake changes circadian activity rhythms, mainly by altering light synchronization that generates the expression of a free-running rhythm with a period longer than 24 h and a second behavioral
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Jonathan Hewitt et al.
The Cochrane database of systematic reviews, 6(6), CD009204-CD009204 (2012-06-15)
Acute kidney injury (AKI) is a common, serious, but potentially treatable condition. Because AKI is often associated with acidosis, it has become common practice to recommend administration of sodium bicarbonate to correct acid imbalance. To assess the benefits and harms
Effect of oral care solutions in reducing ventilator-associated pneumonia: review of current evidence.
E Balamurugan et al.
The Nursing journal of India, 103(6), 282-284 (2013-08-09)
Ratnasekhar Ch et al.
Nature communications, 12(1), 377-377 (2021-01-17)
Circadian clocks coordinate mammalian behavior and physiology enabling organisms to anticipate 24-hour cycles. Transcription-translation feedback loops are thought to drive these clocks in most of mammalian cells. However, red blood cells (RBCs), which do not contain a nucleus, and cannot
Reymond Barreto
Nephrology nursing journal : journal of the American Nephrology Nurses' Association, 34(4), 417-421 (2007-09-26)
The incidence of contrast-induced nephropathy (CIN) is increasing due to the growing number of patients undergoing radiocontrast studies. CIN is associated with a mortality rate as high as 34%. The purpose of this article is to review the strategies for
Faisal Al-Akayleh et al.
Pharmaceutical development and technology, 18(5), 1204-1212 (2011-10-08)
In the present systematic study, a sustained release of terbutaline sulfate tablet (TBS) was developed and optimized by employing the hydrophilic polymers; chitosan and xanthan gum mixed with sodium bicarbonate as a release modifying agent. This formulation was developed using
Suihong Huang et al.
STAR protocols, 2(2), 100416-100416 (2021-04-20)
This protocol combines a protective cutting method to prepare various brain slices from adult mice and real-time monitoring of circadian oscillations to measure circadian rhythmicity in various brain slices. This protocol can be applied to studies of how brain damages
[Transition of acetylsalicylic acid serum concentration in a case of overdose].
Aya Tominaga
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 26(4), 314-315 (2014-02-04)
Edward Nixon Pakpahan et al.
Environmental technology, 34(1-4), 407-416 (2013-03-28)
Petroleum sludge is a hazardous waste that contains various organic compounds including polycyclic aromatic hydrocarbons (PAHs) which have carcinogenic-mutagenic and toxic characteristics. This study focuses on the thermal treatment (indirect heating) of petroleum sludge cake for PAH degradation at 250
Jae-Sik Jang et al.
Circulation journal : official journal of the Japanese Circulation Society, 76(9), 2255-2265 (2012-09-15)
Sodium bicarbonate has been postulated to prevent contrast-induced acute kidney injury (CI-AKI) by various mechanisms, although the reports are conflicting. We searched MEDLINE, EMBASE, and the Cochrane databases for randomized controlled trials that compared a sodium chloride with a sodium
Melissa J Parker et al.
Critical care medicine, 41(9), 2188-2195 (2013-06-14)
To evaluate the preferences and self-reported practices of pediatric acute care physicians with respect to sodium bicarbonate administration to infants and children in shock or cardiac arrest. National survey study utilizing a self-administered questionnaire. Thirteen Canadian pediatric tertiary care centers.
N Alessandri et al.
European review for medical and pharmacological sciences, 17 Suppl 1, 13-21 (2013-04-26)
The contrast-induced nephropathy (CIN) is the third most common cause of acute renal failure (ARF) and the worsening in a pre-existing chronic renal failure (CRF), with a foreseeable increase of morbidity, mortality, length of the stay in hospital and, as
Mette Flinck et al.
Cell cycle (Georgetown, Tex.), 17(9), 1056-1067 (2018-06-14)
Precise acid-base homeostasis is essential for maintaining normal cell proliferation and growth. Conversely, dysregulated acid-base homeostasis, with increased acid extrusion and marked extracellular acidification, is an enabling feature of solid tumors, yet the mechanisms through which intra- and extracellular pH
Tala Shekarian et al.
Science translational medicine, 11(515) (2019-10-28)
Although immune checkpoint-targeted therapies are currently revolutionizing cancer care, only a minority of patients develop durable objective responses to anti-PD-1, PD-L1, and CTLA-4 therapy. Therefore, new therapeutic interventions are needed to increase the immunogenicity of tumors and overcome the resistance
2/4