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关键词:'SeQuant'
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Separation of Polar and Hydrophilic Compounds Using a Zwitterionic Stationary Phase in HILIC
040.041 SeQuant
THEAPPLICATIONSBOOK May 2004, 40–41 (2004)2
General
ZIC®-HILIC Columns
The ZIC®-HILIC columns have a sulfobetaine type zwitterionic
stationary phase covalently attached
Citicoline Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Citicoline
Methotrexate Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Methotrexate
Deticabine Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Decitabine
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Allantoin Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Allantoin
Cisplatin Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Cisplatin
Merck Millipore is a division of Merck KGaA, Darmstadt, Germany
www.merck-chemicals.com/chromatography
Urea Sequant®ZIC®-HILIC
HPLC Application Note: USP method -Urea
NH2H2N
O
Eflornithine Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Eflornithine
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OH
H2N
F
F
H2N
O
Temozolomide and Related Impurities - SeQuant®ZIC®-HILIC
Chromatographic Conditions
Column: SeQuant® ZIC® HILIC (5 μm 200Å) PEEK 250x4 6 mm 1 51458 0001
Temozolomide and Related Impurities
SeQuant® ZIC®-HILIC
Column: SeQuant® ZIC®-HILIC (5.μm, 200Å) PEEK 250x4.6
Ribavirin and Related Substances - SeQuant®ZIC®-cHILIC
Ribavirin and Related Substances
SeQuant® ZIC®-cHILIC
Chromatographic Conditions
Column: SeQuant® ZIC® cHILIC (3μm 100Å) PEEK 150x4 6 mm 1 50661 0001Column: SeQuant ZIC -cHILIC (3μm, 100Å) PEEK 150x4.6
Cisplatin and Related Substances - SeQuant®ZIC®-HILIC
Cisplatin and Related Substances
SeQuant® ZIC®-HILIC
Chromatographic Conditions
C l S Q t® ZIC® HILIC (5 200Å) PEEK 150 2 1 1 50454 0001Column: SeQuant® ZIC®-HILIC (5μm, 200Å) PEEK 150x2.1 mm
Fondaparinux and Related Impurities - SeQuant®ZIC®-cHILIC
Fondaparinux and Related Impurities
SeQuant® ZIC®-cHILIC
Chromatographic Conditions
Column: SeQuant® ZIC® cHILIC (3μm 100Å) PEEK 150×4 6 mm 1 50661 0001Column: SeQuant ZIC -cHILIC (3μm, 100Å) PEEK 150×4.6
It's hot! SeQuant®ZIC®-cHILIC
min at 23 °C.
Detection by UV absorption at 254 nm.
SeQuant® ZIC®-cHILIC SeQuant® ZIC®-HILIC
4
5
Isocratic separations on SeQuant®
ZIC®-cHILIC 100 x 2.1 mm
(Ord. No. 1.50657.0001)
Citicoline and Related Impurities - SeQuant®ZIC®-cHILIC
Citicoline and Related Impurities
SeQuant® ZIC®-cHILIC
Chromatographic Conditions
Column: SeQuant® ZIC® cHILIC (3 μm 100 Å) PEEK 150×4 6 mm 1 50661 0001Column: SeQuant® ZIC®-cHILIC (3 μm, 100 Å) PEEK 150
Decitabine and Related Impurities - SeQuant®ZIC®-HILIC
Chromatographic Conditions
Column: SeQuant® ZIC®-HILIC (5μm 200Å) PEEK 150x4 6 mm 1 50455 0001
Decitabine and Related Impurities
SeQuant® ZIC®-HILIC
Column: SeQuant ZIC HILIC (5μm,200Å) PEEK 150x4.6
Metformin and Related Impurities - SeQuant®ZIC®-cHILIC
Metformin and Related Impurities
SeQuant® ZIC®-cHILIC
Chromatographic Conditions
Column: SeQuant® ZIC® cHILIC (3μm 100Å) PEEK 150x4 6 mm 1 50661 0001Column: SeQuant® ZIC®-cHILIC (3μm, 100Å) PEEK 150x4.6
Chondroitin Sulfate Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Chondroitin Sulfate
0
100
200
300
400
500
600
0 1 2 3 4
2-Chloroethanol Sequant®ZIC®-HILIC
HPLC Application Note: USP method - 2-Chloroethanol
Acetylcysteine Granule Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Acetylcysteine Granules
Organic Acids Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Organic Acids
Adrenaline and Nonadrenaline Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Adrenaline and Noradrenaline
For all who expect more. SeQuant ZIC-HILIC
The better choice for HPLC and LC/MS of all types
of polar and hydrophilic compounds
SeQuant‹ ZIC‹-HILIC
For all who expect more ...
2
Poor retention of polar compounds?
ZIC®-HILIC
A Practical Guide To HILIC - Including ZIC-HILIC applications - SeQuant
Wen Jiang
Editor: Tobias Jonsson
Published by Merck SeQuant AB, Box 7956, 907 19 Umeå, Sweden.
Copyright © 2005-2008, Merck SeQuant AB
1:st edition. 5:th issue. Printed at Original, Umeå
Metformin and Related Impurities Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Metformin
Separation of Carnitine and Impurity A Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Carnitine and Impurity A
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Everything runs smoothly. SeQuant CARS and SAMS Ion Chromatography
continuous background conductivity suppression
system SeQuant™ CARS™ equipped with the membrane
suppressor SeQuant™ SAMS™ to enhance your results.
Low background and high sensitivity in ion
Azacitidine and Related Impurities Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Azacitidine
0 5 10 15 20 25
Temozolimide and Related impurities Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Temozolomide
Pyroglutamic Acid and Related Impurity Sequant®ZIC®-HILIC
HPLC Application Note: USP method - Pyroglutamic Acid
4-Aminobutyrik acid (GABA) Sequant®ZIC®-HILIC
HPLC Application Note: USP method - 4-Aminobutyric acid
0
10
20
30
0 2 4 6 8 10 12 14 16 18 20
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