CN
T5525
应用筛选条件
关键词:'T5525'
显示 1-30 共 801 条结果 关于 "T5525" 范围 论文
Nuriye Korkmaz Zirpel et al.
Macromolecular bioscience, 15(9), 1262-1273 (2015-05-20)
Bacteriophages are filamentous polyelectrolyte viral rods infecting only bacteria. In this study, we investigate the bundle formation of fd phages with trivalent cations having different ionic radii (Al(3+) , La(3+) and Y(3+) ) at various phage and counterion concentrations, and
Juhi Shah et al.
Journal of colloid and interface science, 456, 100-107 (2015-06-27)
Gold nanoparticles (AuNPs) are known to possess intrinsic biological peroxidase-like activity that has applications in development of numerous biosensors. The reactivity of the Au atoms at the surface of AuNPs is critical to the performance of such biosensors, yet little
Jorge L Arias-Arias et al.
Biotechnology reports (Amsterdam, Netherlands), 37, e00780-e00780 (2023-01-10)
SARS-CoV-2 receptor binding domain (RBD) recognizes the angiotensin converting enzyme 2 (ACE2) receptor in host cells that enables infection. Due to its antigenic specificity, RBD production is important for development of serological assays. Here we have established a system for
Wenjie Luo et al.
Scientific reports, 5, 11161-11161 (2015-06-10)
Microglia have been shown to contribute to the clearance of brain amyloid β peptides (Aβ), the major component of amyloid plaques, in Alzheimer's disease (AD). However, it is not known whether microglia play a similar role in the clearance of
Teck-Hui Teo et al.
Journal of virology, 89(15), 7955-7969 (2015-05-23)
Chikungunya virus (CHIKV) is a mosquito-borne arthralgic alphavirus that has garnered international attention as an important emerging pathogen since 2005. More recently, it invaded the Caribbean islands and the Western Hemisphere. Intriguingly, the current CHIKV outbreak in the Caribbean is
Jens E V Petersen et al.
Thrombosis and haemostasis, 114(5), 1038-1048 (2015-07-15)
The Endothelial Protein C receptor (EPCR) is essential for the anticoagulant and cytoprotective functions of the Protein C (PC) system. Selected variants of the malaria parasite protein, Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) associated with severe malaria, including cerebral
Abdullah Alghasham et al.
Nucleosides, nucleotides & nucleic acids, 34(1), 56-68 (2014-12-17)
Present study probes the role of peroxynitrite (ONOO(-))-modified thymidine-5'-monophosphate (TMP) in SLE patients with different disease activity scores according to the SLE Disease Activity Index (SLEDAI). Serum analysis showed significant increased number of subjects positive for anti-ONOO(-)-TMP-protein antibodies in SLE
Gang Chen et al.
ACS chemical biology, 9(10), 2263-2273 (2014-08-21)
The ebolaviruses cause severe and rapidly progressing hemorrhagic fever. There are five ebolavirus species; although much is known about Zaire ebolavirus (EBOV) and its neutralization by antibodies, little is known about Sudan ebolavirus (SUDV), which is emerging with increasing frequency.
Jing Chen et al.
Talanta, 147, 523-530 (2015-11-26)
Immunoassay for cancer biomarkers plays an important role in cancer prevention and early diagnosis. To the development of immunoassay, the quality and stability of applied antibody is one of the key points to obtain reliability and high sensitivity for immunoassay.
Julia C Frei et al.
Virology, 485, 371-382 (2015-09-05)
Here we investigated the binding of Dengue virus envelope glycoprotein domain III (DIII) by two broadly neutralizing antibodies (bNAbs), 4E11 and 4E5A. There are four serotypes of Dengue virus (DENV-1 to -4), whose DIII sequences vary by up to 49%.
Moitza Principe et al.
Oncotarget, 6(13), 11098-11113 (2015-04-11)
Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by rapid progression, invasiveness and resistance to treatment. We have previously demonstrated that most PDAC patients have circulating antibodies against the glycolytic enzyme alpha-enolase (ENO1), which correlates with a better
Mariana Carlomagno et al.
Analytical chemistry, 86(20), 10467-10473 (2014-09-27)
Short peptide loops selected from phage libraries can specifically recognize the formation of hapten-antibody immunocomplexes and can thus be used to develop phage anti-immunocomplex assays (PHAIA) for noncompetitive detection of small molecules. In this study, we generated recombinant chimeras by
Evaristus Chibunna Mbanefo et al.
Parasitology international, 64(4), 24-31 (2015-01-21)
There is still urgent need for a vaccine against schistosomiasis, especially in Schistosoma japonicum endemic areas where even a vaccine that will interrupt zoonotic transmission will be potentially effective as an intervention tool. We had developed a novel nanoparticle gene
Giuseppina Barutello et al.
Oncoimmunology, 4(5), e1005500-e1005500 (2015-07-15)
Maternal immunization is successfully applied against some life-threatening infectious diseases as it can protect the mother and her offspring through the passive transfer of maternal antibodies. Here, we sought to evaluate whether the concept of maternal immunization could also be
Ruimin Li et al.
Biosensors & bioelectronics, 47, 502-507 (2013-05-01)
C60-carboxyfullerene, C60[C(COOH)2]2, has been proven to function as peroxidase mimetics that can catalyze the reaction of peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. Kinetic studies further indicate that C60[C(COOH)2]2 has an even
Wei Song et al.
Scientific reports, 5, 16884-16884 (2015-11-26)
Cellular therapies for liver diseases and in vitro models for drug testing both require functional human hepatocytes (Hum-H), which have unfortunately been limited due to the paucity of donor liver tissues. Human pluripotent stem cells (hPSCs) represent a promising and
Giulia Pezzoni et al.
Journal of virological methods, 207, 95-103 (2014-07-11)
Hepatitis E virus (HEV) is a RNA non-enveloped virus that comprises four genotypes. The genome of HEV is organized into three Open Reading Frames (ORFs), and the ORF2 is responsible for encoding capsid proteins. HEV can infect a wide range
Hirokuni Akahori et al.
Nature communications, 6, 7792-7792 (2015-08-06)
Macrophages are an essential component of the immune response to ischaemic injury and play an important role in promoting inflammation and its resolution, which is necessary for tissue repair. The type I transmembrane glycoprotein CD163 is exclusively expressed on macrophages
Joshua C Bunger et al.
Toxins, 7(6), 2306-2320 (2015-06-26)
Shiga toxin (Stx) is an AB5 ribotoxin made by Stx-producing Escherichia coli (STEC). These organisms cause diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome. STEC make two types of Stxs, Stx1 and/or Stx2. Stx2 has one prototype (a) and six
James Hutchenreuther et al.
The Journal of investigative dermatology, 135(11), 2805-2813 (2015-07-15)
Metastatic melanoma has an extremely poor prognosis with few durable remissions. The secreted matricellular protein connective tissue growth factor (CCN2) is overexpressed in cancers including melanoma and may represent a viable therapeutic target. However, the mechanism underlying the contribution of
Arindam Maity et al.
Molecules (Basel, Switzerland), 20(6), 10253-10263 (2015-06-06)
Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications. Herein, we demonstrate how the CuAAC method can provide novel phospholipid-protein conjugates with a high potential for the diagnostics and therapy
Eglė Jakubauskienė et al.
Cancer biomarkers : section A of Disease markers, 15(5), 575-581 (2015-09-26)
Cell lines derived from human tumors have been extensively used as experimental models of neoplastic disease. Although such cell lines differ from both normal and cancerous tissue. The data obtained used DNA and RNA microarray systems does not give full
Bao Zhong Zhang et al.
Infection and immunity, 83(1), 339-345 (2014-11-05)
Staphylococcus aureus is a common pathogen found in the community and in hospitals. Most notably, methicillin-resistant S. aureus is resistant to many antibiotics, which is a growing public health concern. The emergence of drug-resistant strains has prompted the search for
A multiplex method for the detection of serum antibodies against in silico-predicted tumor antigens.
Miriam Reuschenbach et al.
Cancer immunology, immunotherapy : CII, 63(12), 1251-1259 (2014-08-22)
Humoral immune responses against tumor antigens are studied as indirect markers of antigen exposure and in cancer vaccine studies. An increasing number of tumor antigens potentially translated from mutant genes is identified by advances in genomic sequencing. They represent an
Anne-Sophie Bergot et al.
Immunology and cell biology, 93(6), 540-547 (2015-01-21)
Atopic dermatitis is a common pruritic and inflammatory skin disorder with unknown etiology. Most commonly occurring during early childhood, atopic dermatitis is associated with eczematous lesions and lichenification, in which the epidermis becomes hypertrophied resulting in thickening of the skin.
Jiaming Lan et al.
PloS one, 9(11), e112602-e112602 (2014-11-19)
The development of an effective vaccine is critical for prevention of a Middle East respiratory syndrome coronavirus (MERS-CoV) pandemic. Some studies have indicated the receptor-binding domain (RBD) protein of MERS-CoV spike (S) is a good candidate antigen for a MERS-CoV
Ling Liu et al.
Molecular medicine reports, 11(4), 3015-3020 (2014-12-09)
The glycoprotein, von Willebrand factor (VWF) is a carrier protein for factor VIII. When bound to platelets and the extracellular matrix, it promotes aggregation or adhesion of platelets to areas of vascular damage. A disintegrin and metalloproteinase with thrombospondin motif
Takeshi Tomita et al.
PloS one, 10(3), e0118835-e0118835 (2015-03-05)
Serum amyloid A3 (SAA3) possesses characteristics distinct from the other serum amyloid A isoforms, SAA1, SAA2, and SAA4. High density lipoprotein contains the latter three isoforms, but not SAA3. The expression of mouse SAA3 (mSAA3) is known to be up-regulated
Beatriz Cabanillas et al.
Food chemistry, 183, 18-25 (2015-04-13)
This study aimed to analyze the influence of thermal processing on the IgE binding properties of three forms of peanut, its effects in the content of individual allergens and IgE cross-linking capacity in effector cells of allergy. Three forms of
Ilka Sührer et al.
Microbial cell factories, 14, 180-180 (2015-11-19)
Whole cell biocatalysts and isolated enzymes are considered as state of the art in biocatalytic preparations for industrial applications. Whole cells as biocatalysts are disadvantageous if substrate or products are toxic to the cells or undesired byproducts are formed due
1/27