CN
Search Within
V900445
应用筛选条件
关键词:'V900445'
显示 1-30 共 243 条结果 关于 "V900445" 范围 论文
L Masucci et al.
Ontario health technology assessment series, 13(24), 1-24 (2014-01-01)
Vitamin B12 deficiency can lead to adverse health effects such as anemia and, in some cases, permanent neurologic damage. In Canada, patients with vitamin B12 deficiency are typically given intramuscular injections, which incur considerable cost and inconvenience. The clinical evidence-based
J Efraim Oosterink et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 998-999, 106-113 (2015-07-22)
Methionine, homocysteine, vitamins B6, B12, B9, and their metabolites are crucial co-factors and substrates for many basic biological pathways including one-carbon metabolism, and they are particularly important for brain function and development and epigenetic mechanisms. These are essential nutrients that
Esmée L Doets et al.
Annals of nutrition & metabolism, 62(4), 311-322 (2013-06-26)
To systematically review the literature on daily losses and bioavailability of vitamin B12. These estimates could be used for deriving recommendations on vitamin B12 intake for adults and elderly. We identified publications on daily vitamin B12 losses (July 2011) and
Sharmistha Sinha et al.
Journal of molecular biology, 426(12), 2328-2345 (2014-04-22)
Bacterial microcompartments (MCPs) are the simplest organelles known. They function to enhance metabolic pathways by confining several related enzymes inside an all-protein envelope called the shell. In this study, we investigated the factors that govern MCP assembly by performing scanning
[Current aspects of physiology and physiopathology of cyanocobalamin metabolism].
V Fica et al.
Fiziologia normala si patologica, 17(4), 301-312 (1971-07-01)
Martin Bommer et al.
Science (New York, N.Y.), 346(6208), 455-458 (2014-10-04)
Organohalide-respiring microorganisms can use a variety of persistent pollutants, including trichloroethene (TCE), as terminal electron acceptors. The final two-electron transfer step in organohalide respiration is catalyzed by reductive dehalogenases. Here we report the x-ray crystal structure of PceA, an archetypal
Angelo Macri et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 253(3), 425-430 (2014-11-16)
Increased levels of oxidative stress have been seen in animal models of dry eye and in the conjunctival epithelial cells of patients with Sjögren's syndrome. The aims of this study were to compare the levels of oxidative stress in patients
M C F J de Rotte et al.
Arthritis and rheumatism, 65(11), 2803-2813 (2013-10-30)
To investigate whether baseline concentrations of one-carbon metabolism biomarkers are associated with treatment nonresponse and adverse events in rheumatoid arthritis (RA) patients receiving methotrexate (MTX). A prospective derivation cohort (n = 285) and validation cohort (n = 102) of RA
Sereyvath Yoeun et al.
Journal of plant research, 128(1), 201-209 (2014-10-20)
Allene oxide synthase-1 from Oryza sativa (OsAOS1) localizes to the chloroplast, but lacks a putative chloroplast targeting sequence typically found in dicot AOS. Here, kinetic parameters and the oligomerization state/subunit composition of OsAOS1 were characterized in vitro in the absence
Binuraj R K Menon et al.
The Journal of biological chemistry, 289(49), 34161-34174 (2014-09-13)
Cobalamin-dependent enzymes enhance the rate of C-Co bond cleavage by up to ∼10(12)-fold to generate cob(II)alamin and a transient adenosyl radical. In the case of the pyridoxal 5'-phosphate (PLP) and cobalamin-dependent enzymes lysine 5,6-aminomutase and ornithine 4,5 aminomutase (OAM), it
J A Kable et al.
Alcohol (Fayetteville, N.Y.), 49(7), 647-656 (2015-10-24)
The potential of micronutrients to ameliorate the impact of prenatal alcohol exposure (PAE) was explored in a clinical trial conducted in Ukraine. Cardiac orienting responses (ORs) during a habituation/dishabituation learning paradigm were obtained from 6 to 12 month-olds to assess
Shen-Chih Chang et al.
Nutrition and cancer, 67(2), 212-223 (2015-01-22)
Evidence is accumulating regarding a role of micronutrients in folate metabolism in cancer risk. We investigated the associations of plasma folate, vitamin B12, and homocysteine with upper gastrointestinal (GI) cancers in a population-based case-control study in Taixing City, China. With
Yue Yu et al.
Applied microbiology and biotechnology, 99(24), 10481-10488 (2015-09-17)
The vitamin B12-dependent riboswitch is a crucial factor that regulates gene transcription to mediate the growth of and vitamin B12 synthesis by Propionibacterium freudenreichii. In this study, the effect of various wavelengths of light on the growth rate and vitamin
Ava Grace Tan et al.
Investigative ophthalmology & visual science, 56(1), 216-220 (2014-11-20)
We assessed associations between serum levels of homocysteine, vitamin B12, and folate, and the prevalence and 5-year incidence of posterior subcapsular cataract (PSC) in Blue Mountains Eye Study participants. We examined 3508 participants aged 49+ years during 1997 to 2000
Vaughn Mangal et al.
Analytical and bioanalytical chemistry, 407(15), 4305-4313 (2015-03-17)
In this study, molecular weights of thiols from four laboratory cultures (Scenedesmus obliquus, Chlorella vulgaris, Euglena gracilis, and Attheya septentrionalis) and the Churchill River (Manitoba) were assessed using a fluorescent-labeling method such as monobromotrimethylammoniobimane (qBBr) and asymmetrical flow field-flow fractionation
Jinju Jeong et al.
BMB reports, 46(3), 169-174 (2013-03-27)
The human B(12) trafficking chaperone hCblC is well conserved in mammals and non-mammalian eukaryotes. However, the C-terminal ~40 amino acids of hCblC vary significantly and are predicted to be deleted by alternative splicing of the encoding gene. In this study
Roy Lardenoije et al.
Progress in neurobiology, 131, 21-64 (2015-06-15)
Epigenetics is a quickly growing field encompassing mechanisms regulating gene expression that do not involve changes in the genotype. Epigenetics is of increasing relevance to neuroscience, with epigenetic mechanisms being implicated in brain development and neuronal differentiation, as well as
P Satora et al.
Journal of applied microbiology, 119(3), 736-743 (2015-07-15)
To investigate the synthesis of selected bioactive compounds in various strains belonging to the Arthrospira genus. The synthesis of vitamin C, polyphenols, vitamin B12, fatty acids and selected volatile compounds (acetone and acetaldehyde) was investigated in six strains belonging to
Tomohiro Bito et al.
FEBS open bio, 4, 722-729 (2014-08-28)
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5'-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized. The levels of methylmalonic acid and homocysteine, which serve as indicators
Dezhi Kang et al.
Science translational medicine, 7(293), 293ra103-293ra103 (2015-06-26)
Various diseases have been linked to the human microbiota, but the underlying molecular mechanisms of the microbiota in disease pathogenesis are often poorly understood. Using acne as a disease model, we aimed to understand the molecular response of the skin
Managing severe anemia when the patient is a Jehovah's Witness.
Shannon Lynn et al.
JAAPA : official journal of the American Academy of Physician Assistants, 26(4), 24-24 (2013-04-25)
Jean-Louis Guéant et al.
Biochimie, 95(5), 1033-1040 (2013-02-19)
Vitamin B12 (cobalamin, cbl) is a cofactor of methionine synthase (MTR) in the synthesis of methionine, the precursor of the universal methyl donor S-Adenosylmethionine (SAM), which is involved in epigenomic regulatory mechanisms. We have established a neuronal cell model with
Jae Hoon Moon et al.
Stroke, 46(4), 1024-1030 (2015-03-05)
We investigated the association between cardiovascular risk factors, including carotid intima-media thickness (CIMT), and future risk of mild cognitive impairment (MCI) and dementia in elderly subjects. We conducted a population-based prospective study as a part of the Korean Longitudinal Study
Bamini Gopinath et al.
The American journal of clinical nutrition, 98(1), 129-135 (2013-05-03)
Epidemiologic evidence of a relation between serum total homocysteine (tHcy), vitamin B-12, and folate and age-related macular degeneration (AMD) is inconsistent and unresolved. In this cohort study, we aimed to investigate associations between intakes and serum concentrations of folate and
Sachchida Nand Pandey et al.
Molecules (Basel, Switzerland), 20(5), 8304-8315 (2015-05-27)
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of double homeobox 4 (DUX4) due to epigenetic changes of the D4Z4 region at chromosome 4q35. Detecting DUX4 is challenging due to its stochastic expression pattern and low
Clinical analysis of late-onset methylmalonic acidaemia and homocystinuria, cblC type with a neuropsychiatric presentation.
Yan-ru Liu et al.
Journal of neurology, neurosurgery, and psychiatry, 86(4), 472-475 (2014-08-06)
C W Wong et al.
Experimental gerontology, 69, 221-225 (2015-07-01)
The prevalence of vitamin B12 deficiency increases with age and is suggested to be even higher in the elderly living in institutions. This retrospective study evaluated the vitamin B12 and folate status of 1996 institutionalized elderly residents aged over 65years.
H Zhou et al.
Minerva medica, 106(4), 215-219 (2015-09-30)
Comparative analysis of the effect of antiepileptic drugs on the epileptic (tonic clonic seizure type) patient's serum folate and vitamin B12 concentrations. Consecutively, 84 cases from September 2010 to September 2014 from the Department of Internal Medicine of our hospital
Chenggui Liu et al.
Saudi medical journal, 36(7), 839-846 (2015-06-26)
To study the associations between hyperhomocysteinemia (HHcy) and the severity of coronary heart disease (CHD). We retrospectively analyzed metabolic parameters, anthropometric variables, and life style habits in 292 CHD patients of different categories, and 100 controlled non-CHD patients with chest
Quantitative hopanoid analysis enables robust pattern detection and comparison between laboratories.
C-H Wu et al.
Geobiology, 13(4), 391-407 (2015-04-14)
Hopanoids are steroid-like lipids from the isoprenoid family that are produced primarily by bacteria. Hopanes, molecular fossils of hopanoids, offer the potential to provide insight into environmental transitions on the early Earth, if their sources and biological functions can be
1/9