W281506

应用筛选条件

关键词:'W281506'

显示 1-30 共 536 条结果关于 "W281506" 范围论文

Iron oxide nanoparticle-mediated development of cellular gap junction crosstalk to improve mesenchymal stem cells' therapeutic efficacy for myocardial infarction.

Jin Han et al.

ACS nano, 9(3), 2805-2819 (2015-02-18)

Electrophysiological phenotype development and paracrine action of mesenchymal stem cells (MSCs) are the critical factors that determine the therapeutic efficacy of MSCs for myocardial infarction (MI). In such respect, coculture of MSCs with cardiac cells has windowed a platform for

The effect of hyperglycemia on the pharmacokinetics of valproic acid studied by high-performance liquid chromatography with electrochemical detection.

Akira Kotani et al.

Journal of pharmaceutical and biomedical analysis, 97, 47-53 (2014-05-13)

The effects of hyperglycemia on the pharmacokinetics of valproic acid (VPA) were examined by time-concentration profiles of plasma VPA accompanied with blood glucose (BG) changing. In addition, time-concentration profiles of plasma free fatty acids (FFAs) were also obtained to examine

Suitable in vitro Eimeria arloingi macromeront formation in host endothelial cells and modulation of adhesion molecule, cytokine and chemokine gene transcription.

Liliana M R Silva et al.

Parasitology research, 114(1), 113-124 (2014-10-24)

Eimeria arloingi infections can cause severe haemorrhagic enteritis in young goat kids, thereby leading to high economic losses in goat industry worldwide. We aimed to isolate a new E. arloingi strain and establish a suitable in vitro culture system for

How relevant are assembled equilibrium samples in understanding structure formation during lipid digestion?

Stephanie Phan et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 117-124 (2015-07-28)

Lipid-based formulations are gaining interest for use as drug delivery systems for poorly water-soluble drug compounds. During digestion, the lipolysis products self-assemble with endogenous surfactants in the gastrointestinal tract to form colloidal structures, enabling enhanced drug solubilisation. Although earlier studies

Tumor-targeted responsive nanoparticle-based systems for magnetic resonance imaging and therapy.

Ronak Savla et al.

Pharmaceutical research, 31(12), 3487-3502 (2014-06-13)

Design and synthesis of a tumor responsive nanoparticle-based system for imaging and treatment of various cancers. Manganese oxide nanoparticles (Mn3O4 NPs) were synthesized and modified with LHRH targeting peptide or anti-melanoma antibodies (cancer targeting moieties) and a MMP2 cleavable peptide

Endogenous fatty acids in olfactory hairs influence pheromone binding protein structure and function in Lymantria dispar.

Jason Nardella et al.

Archives of biochemistry and biophysics, 579, 73-84 (2015-06-04)

The gypsy moth utilizes a pheromone, (7R,8S)-2-methyl-7,8-epoxyoctadecane, for mate location. The pheromone is detected by sensory hairs (sensilla) on the antennae of adult males. Sensilla contain the dendrites of olfactory neurons bathed in lymph, which contains pheromone binding proteins (PBPs).

[Nutrition value of tropical and subtropical fruits].

G G Dubtsov et al.

Voprosy pitaniia, 82(1), 41-44 (2013-07-03)

The article is devoted to the study of the chemical composition of tropical and subtropical fruit (avocado, papaya and mango), which are now in great numbers are on the appeared on the Russian market. Due to use technology tropical and

Free Fatty Acids Impair FGF21 Action in HepG2 Cells.

Mohamed Asrih et al.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 37(5), 1767-1778 (2015-11-20)

Fibroblast growth factor 21 (FGF21) is a key mediator of glucose and lipid metabolism. However, the beneficial effects of exogenous FGF21 administration are attenuated in obese animals and humans with elevated levels of circulating free fatty acids (FFA). We investigated

Enhancement of Palmarumycin C12 and C13 Production by the Endophytic Fungus Berkleasmium sp. Dzf12 in an Aqueous-Organic Solvent System.

Yan Mou et al.

Molecules (Basel, Switzerland), 20(11), 20320-20333 (2015-11-17)

The endophytic fungus Berkleasmium sp. Dzf12, isolated from Dioscorea zingiberensis, was found to produce palmarumycins C12 and C13 which possess a great variety of biological activities. Seven biocompatible water-immiscible organic solvents including n-dodecane, n-hexadecane, 1-hexadecene, liquid paraffin, dibutyl phthalate, butyl

Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids.

Andrew D Southam et al.

Cancer research, 75(12), 2530-2540 (2015-05-07)

The redeployed drug combination of bezafibrate and medroxyprogesterone acetate (designated BaP) has potent in vivo anticancer activity in acute myelogenous leukemia (AML) and endemic Burkitt lymphoma (eBL) patients; however, its mechanism-of-action is unclear. Given that elevated fatty acid biosynthesis is

Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury.

Muiris T Kennedy et al.

BMC pulmonary medicine, 8, 9-9 (2008-07-10)

Hypertonic saline (HTS) reduces the severity of lung injury in ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. However, the potential for HTS to modulate the resolution of lung injury is not known. We investigated the potential for hypertonic saline to modulate

Behenic acid is a cholesterol-raising saturated fatty acid in humans.

N B Cater et al.

The American journal of clinical nutrition, 73(1), 41-44 (2000-12-22)

Dietary behenic acid (22:0) is poorly absorbed. Because of its low bioavailability compared with other fatty acids and because of its very long chain length, the effect of dietary behenic acid (behenate) on serum lipid concentrations in humans is assumed

Self-limiting adsorption of Eu³⁺ on the surface of rod-shape anatase TiO₂ nanocrystals and post-synthetic sensitization of the europium-based emission.

Choumini Balasanthiran et al.

Journal of colloid and interface science, 459, 63-69 (2015-08-12)

The surface of oleic acid stabilized rod-shape anatase TiO2 nanocrystals was modified by adsorption of Eu(3+) ions. The Eu(3+) attachment showed Langmuir adsorption behavior, thus the loading of Eu(3+) could be controlled precisely up to surface saturation coverage. The Eu(3+)-TiO2

Triple-doped KMnF3:Yb3+/Er3+/Tm3+ nanocubes: four-color upconversion emissions with strong red and near-infrared bands.

Hao Wang et al.

Scientific reports, 5, 17088-17088 (2015-11-27)

Triple-doped (Yb(3+)/Er(3+)/Tm(3+)) KMnF3 nanocubes with uniform sizes of 250 nm were synthesized by a facile hydrothermal route using the oleic acid as the capping agent. It was found that these nanocubes can simultaneously exhibited four-color (blue, green, red and NIR)

Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ.

Lianying Zhang et al.

Toxicology and applied pharmacology, 279(3), 275-283 (2014-07-08)

Perfluorinated compounds (PFCs) have been shown to disrupt lipid metabolism and even induce cancer in rodents through activation of peroxisome proliferator-activated receptors (PPARs). Lines of evidence showed that PPARα was activated by PFCs. However, the information on the binding interactions

In vitro MRI of biodegradable hybrid (iron oxide/polycaprolactone) magnetic nanoparticles prepared via modified double emulsion evaporation mechanism.

Naveed Ahmed et al.

Colloids and surfaces. B, Biointerfaces, 130, 264-271 (2015-05-12)

Hybrid magnetic particles are being applied in biomedical field for various aims. One of such aim is use of magnetic particles for diagnostic purposes especially in imaging mechanisms. In vitro magnetic resonance imaging of biodegradable hybrid (iron oxide/polycaprolactone) magnetic nanoparticles

Photoactive hybrid material based on pyrene functionalized PbS nanocrystals decorating CVD monolayer graphene.

Chiara Ingrosso et al.

ACS applied materials & interfaces, 7(7), 4151-4159 (2015-02-17)

A simple and facile solution-based procedure is implemented for decorating a large area, monolayer graphene film, grown by chemical vapor deposition, with size-tunable light absorbing colloidal PbS nanocrystals (NCs). The hybrid is obtained by exposing a large area graphene film

Capillary electrophoresis study on segment/segment system for segments based on phase of mixed micelles and its role in transport of particles between the two segments.

Sławomir Oszwałdowski et al.

Journal of chromatography. A, 1412, 139-150 (2015-08-25)

Capillary electrophoresis coupled with contactless conductivity detector was applied to characterize BGE/segment/segment/BGE and BGE/segment/electrolyte/segment/BGE systems, where segment is the phase of mixed micelles migrating surrounded by BGE and composition of the first segment≠second segment. It was established that both systems

ARDS: clinical lessons from the oleic acid model of acute lung injury.

D P Schuster

American journal of respiratory and critical care medicine, 149(1), 245-260 (1994-01-01)

Monitoring the formation of cholesterol oxidation products in model systems using response surface methodology.

Joong-Seok Min et al.

Lipids in health and disease, 14, 77-77 (2015-07-24)

Cholesterol oxidation products (COPs) are produced during thermal processing of animal origin foods and are considered to have negative health impacts. The model systems are helpful to understand the impact of various factors on oxidation changes in foods during cooking

Novel approach to improve permeation of ondansetron across shed snake skin as a model membrane.

K Takahashi et al.

The Journal of pharmacy and pharmacology, 53(6), 789-794 (2001-06-29)

The purpose of this study was to investigate the feasibility of transdermal drug delivery of ondansetron, an antagonist of the 5-HT3 receptor, used for the treatment of chemotherapy-induced emesis. The permeability of ondansetron from an aqueous suspension through shed snake

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E.

Yinhua Ni et al.

Scientific reports, 5, 17192-17192 (2015-11-26)

Hepatic insulin resistance and nonalcoholic steatohepatitis (NASH) could be caused by excessive hepatic lipid accumulation and peroxidation. Vitamin E has become a standard treatment for NASH. However, astaxanthin, an antioxidant carotenoid, inhibits lipid peroxidation more potently than vitamin E. Here

The interplay between glucose and fatty acids on tube formation and fatty acid uptake in the first trimester trophoblast cells, HTR8/SVneo.

Sanjay Basak et al.

Molecular and cellular biochemistry, 401(1-2), 11-19 (2014-11-22)

The study aims to investigate the impacts of hyperglycemia in the presence of fatty acids on early placentation processes that involves tube formation, cellular growth and proliferation, and metabolic activities of the first trimester trophoblast cells. Effects of maternal circulatory

Synthesis of magnetic cobalt ferrite nanoparticles with controlled morphology, monodispersity and composition: the influence of solvent, surfactant, reductant and synthetic conditions.

Le T Lu et al.

Nanoscale, 7(46), 19596-19610 (2015-11-07)

In our present work, magnetic cobalt ferrite (CoFe2O4) nanoparticles have been successfully synthesised by thermal decomposition of Fe(III) and Co(II) acetylacetonate compounds in organic solvents in the presence of oleic acid (OA)/ oleylamine (OLA) as surfactants and 1,2-hexadecanediol (HDD) or

Synthesis and characterization of the antitubercular phenazine lapazine and development of PLGA and PCL nanoparticles for its entrapment.

Narjara Silveira et al.

Materials science & engineering. C, Materials for biological applications, 58, 458-466 (2015-10-20)

The aim of this work was to develop and characterize nanoparticles as carriers of lapazine, a phenazine derived from β-lapachone; its antimycobacterial activity is described for the first time as a potential treatment for tuberculosis. The lapazine was synthesized, and

[In vivo peroxidation regulation as a stage of inflammation. Oleic acid, acceptors of active oxygen forms, and antioxidants].

V N Titov et al.

Klinicheskaia laboratornaia diagnostika, (6)(6), 3-12 (2005-08-05)

Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.

Xia Gao et al.

Biochimica et biophysica acta, 1851(2), 152-162 (2014-12-03)

Mice lacking phosphatidylethanolamine N-methyltransferase (PEMT, Pemt(-/-) mice) are resistant to high-fat diet (HFD)-induced obesity (DIO) but develop non-alcoholic steatohepatitis. PEMT expression is strongly induced during differentiation of 3T3-L1 adipocytes. Hence, we hypothesized that white adipose tissue (WAT) might be a

Co-delivery of Pirarubicin and Paclitaxel by Human Serum Albumin Nanoparticles to Enhance Antitumor Effect and Reduce Systemic Toxicity in Breast Cancers.

Xiaoli Yi et al.

Molecular pharmaceutics, 12(11), 4085-4098 (2015-10-01)

In our study, we aimed to develop a codelivery nanoparticulate system of pirarubicin (THP) and paclitaxel (PTX) (Co-AN) using human serum albumin to improve the therapeutic effect and reduce systemic toxicities. The prepared Co-AN demonstrated a narrow size distribution around

Solid-State Conversion Chemistry of Multicomponent Nanocrystals Cast in a Hollow Silica Nanosphere: Morphology-Controlled Syntheses of Hybrid Nanocrystals.

Yeon Jun Kim et al.

ACS nano, 9(11), 10719-10728 (2015-10-31)

During thermal transformation of multicomponent nanocrystals in a silica nanosphere, FeAuPd alloy nanocrystals migrate outward and thereby leave a cavity in the silica matrix. Oxidation then converts these nanocrystals back into phase-segregated hybrid nanocrystals, AuPd@Fe3O4, with various morphologies. The FeAuPd-to-AuPd@Fe3O4

Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance.

Hye Y Kim et al.

Journal of hepatology, 63(2), 477-485 (2015-02-04)

Most studies on the role of STAMP2 in metabolism have used adipose tissue. Little knowledge exists concerning the role of STAMP2 in the liver, which is a metabolically central target. We hypothesized that STAMP2 is involved in non-alcoholic fatty liver

1/18