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Erman Karakuş et al.
Analytica chimica acta, 1182, 338939-338939 (2021-10-05)
Since emerging in China in December 2019, COVID-19 has spread globally, wreaked havoc for public health and economies worldwide and, given the high infectivity and unexpectedly rapid spread of the virus responsible-that is, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-urged
Courtney Tindle et al.
eLife, 10 (2021-09-01)
SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model that is
Alejandro Maruri et al.
Theriogenology, 119, 143-149 (2018-07-15)
The coculture with somatic cells is an alternative to improve suboptimal in vitro culture (IVC) conditions and promote embryo development. Several cell types have been used for this purpose, but there is no information about using luteal cells in short-term coculture
Jun Zhao et al.
Nanotechnology, 25(40), 405101-405101 (2014-09-12)
The treatment of liver injuries or hepatocellular carcinoma (HCC) has been hindered by the lack of efficient drug delivery. Even with the help of nanoparticles or other synthetic delivering agents, a large portion of the dose is still sequestered in
Yan-Ming Liu et al.
Colloids and surfaces. B, Biointerfaces, 122, 287-293 (2014-07-30)
A label-free and ultrasensitive electrochemiluminescence (ECL) aptasensor was constructed for the detection of thrombin. Molybdenum sulfide-graphene nanocomposites with good conductivity and large surface area were immobilized on glassy carbon electrode (GCE), and then Nafion was fixed to chemosorb the Ru(bpy)3(2+)
Elena G Zemtsova et al.
Nanomaterials (Basel, Switzerland), 11(10) (2021-10-24)
The development of new composites with improved functional properties is the important task of modern materials science. The composites must be structurally organized to provide improved properties. For metal-ceramic composites, there is a need for a uniform distribution of the
Alyson Parris et al.
Methods in molecular biology (Clifton, N.J.), 1212, 141-161 (2015-03-13)
The intestinal epithelium is one of the most rapidly renewing tissues in the human body and fulfils vital physiological roles such as barrier function and transport of nutrients and fluid. Investigation of gut epithelial physiology in health and disease has
Anh H Nguyen et al.
Biosensors & bioelectronics, 67, 443-449 (2014-09-16)
Circulating tumor DNA (ctDNA) bearing tumor-specific mutation and methylation are promising biomarkers for noninvasive cancer assessment. However, existing methods for ctDNA detection are restricted to genetic mutations. Recently, nanoplasmonics has emerged as a platform for one-step dual detection with high
Seyda Korkut et al.
Environmental technology, 37(2), 163-171 (2015-06-24)
The present work reported a compartment-less enzymatic fuel cell (EFC) based on newly synthesized Poly(pyrrole-2-carboxylic acid-co-3-thiophene acetic acid) film containing glucose oxidase and laccase effectively wired by p-benzoquinone incorporated into the copolymer structure. The resulting system generated a power density
Development of better-quality assay method for the citric acid and sodium citrate in ophthalmic/oral solutions and their application to deformulation studies
Hotha KK, et al.
American Journal of Analytical Chemistry, 5, 1249-1249 (2014)
Boris G Ershov et al.
Physical chemistry chemical physics : PCCP, 17(28), 18431-18436 (2015-06-25)
The impact of the size of gold nanoparticles on the magnitude of the bathochromic shift of their plasmon resonance peak upon ozone adsorption is revealed and analyzed. Namely, the plasmon band position of 7, 10, 14 and 32 nm nanoparticles
Kira A Watkins et al.
International journal of pharmaceutics, 478(2), 496-503 (2014-12-10)
Hydrogels synthesized from poly(l-lysine isophthalamide) (PLP) crosslinked with l-lysine methyl ester were investigated as drug delivery systems for a wide size range of molecules (0.3-2000kDa). PLP is an anionic, pseudo-peptidic polymer that is an ideal hydrogel backbone due to its
Matthew Edwards et al.
Journal of chromatography. A, 1402, 110-123 (2015-06-02)
Comprehensive two-dimensional gas chromatography (GC×GC) is recognised as a powerful tool for the separation of complex mixtures of volatile and semi-volatile compounds. In the analysis of challenging samples containing highly concentrated, active analytes or those with complicated matrices, it is
Hiroyuki Yanagisawa et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(7), 635-641 (2015-07-15)
The effect of the sp(2)/sp(3) ratio in an unbalanced magnetron sputtered nanocarbon film electrode was studied for determining Cd(2+) and Pb(2+) by anodic stripping voltammetry (ASV). The signal-to-noise ratio in the ASV measurement improved as the sp(3) concentration in the
Kurian A Kuttiyiel et al.
Nature communications, 5, 5185-5185 (2014-11-07)
Considerable efforts to make palladium and palladium alloys active catalysts and a possible replacement for platinum have had a marginal success. Here we report on a structurally ordered Au10Pd₄₀Co₅₀ catalyst that exhibits comparable activity to conventional platinum catalysts in both
Fang Gao et al.
Talanta, 143, 344-352 (2015-06-17)
Sudan I is a carcinogenic and mutagenic azo-compound that has been utilized as a common adulterant in spice and spice blends to impart a desirable red color to foods. A novel biosensor combining molecularly imprinted polymers (MIPs), thin layer chromatography
Kamil Przyborowski et al.
PloS one, 10(6), e0130908-e0130908 (2015-06-27)
1-Methylnicotinamide (MNA), which was initially considered to be a biologically inactive endogenous metabolite of nicotinamide, has emerged as an anti-thrombotic and anti-inflammatory agent with the capacity to release prostacyclin (PGI2). In the present study, we characterized the effects of MNA
Haijian Luo et al.
Molecular and cellular biochemistry, 397(1-2), 215-222 (2014-08-28)
Granulocyte colony-stimulating factor (G-CSF) is a controversial chemical in cardiac cell therapy. Myocardial homing of mobilized bone marrow-derived cells is thought to play a critical role in observed G-CSF-induced cardiac repair; meanwhile, the activation of proliferative potential of cardiac stem
Shuang Yang et al.
Nature protocols, 12(6), 1229-1244 (2017-05-19)
Glycosylation has a pivotal role in a diverse range of biological activities, modulating the structure and function of proteins. Glycogens coupled to the nitrogen atom (N-linked) of asparagine side chains or to the oxygen atom (O-linked) of serine and threonine
Chaofan Li et al.
Immunity, 51(3), 491-507 (2019-09-19)
Tissue-resident memory CD8+ T (Trm) cells share core residency gene programs with tumor-infiltrating lymphocytes (TILs). However, the transcriptional, metabolic, and epigenetic regulation of Trm cell and TIL development and function is largely undefined. Here, we found that the transcription factor
Characterization of sodium tripolyphosphate and sodium citrate dehydrate residues on surfaces
Gurses MS, et al.
Talanta, 176, 8-16 (2018)
Yang-Chi Fan et al.
Journal of AOAC International, 98(3), 575-579 (2015-05-31)
Danofloxacin is an antibacterial drug of the fluoroquinolone group developed for therapeutic purposes in veterinary medicine. The studies described here include investigations of the residues following a single dose or multiple doses of danofloxacin. Residue depletion studies were performed to
Giovanni Bellomo et al.
PloS one, 11(11), e0165730-e0165730 (2016-11-11)
Prostate cancer (PCa) is the most common non-cutaneous cancer in male subjects and the second leading cause of cancer-related death in developed countries. The necessity of a non-invasive technique for the diagnosis of PCa in early stage has grown through
Yifeng Wang et al.
Materials science & engineering. C, Materials for biological applications, 53, 222-228 (2015-06-05)
Electrodeposition of chitosan provides a controllable means to simultaneously assemble biological materials and nanoparticles for various applications. Here, we present a new method to construct biopolymer/nanoparticle composite films with conductivity and antibacterial activity by electrodeposition of chitosan/gelatin/nanosilver. Besides, this method
Mariano D Susman et al.
Small (Weinheim an der Bergstrasse, Germany), 11(32), 3942-3953 (2015-05-06)
Galvanic replacement reactions (GRRs) on nanoparticles (NPs) are typically performed between two metals, i.e., a solid metal NP and a replacing salt solution of a more noble metal. The solution pH in GRRs is commonly considered an irrelevant parameter. Yet
Robrecht Thoonen et al.
Nature communications, 6, 8482-8482 (2015-10-08)
Oxidative stress, a central mediator of cardiovascular disease, results in loss of the prosthetic haem group of soluble guanylate cyclase (sGC), preventing its activation by nitric oxide (NO). Here we introduce Apo-sGC mice expressing haem-free sGC. Apo-sGC mice are viable
P A Mosier-Boss et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 153, 591-598 (2015-10-07)
SERS substrates were fabricated by filtering either Ag or Au colloidal particles onto rigid, ceramic filters - onto which suspensions of bacteria were then filtered. SERS spectra of the bacteria were obtained using a Raman spectrometer that has an 'orbital
Zsuzsanna Tucsek et al.
GeroScience, 39(4), 385-406 (2017-07-01)
Strong epidemiological and experimental evidence indicates that hypertension has detrimental effects on the cerebral microcirculation and thereby promotes accelerated brain aging. Hypertension is an independent risk factor for both vascular cognitive impairment (VCI) and Alzheimer's disease (AD). However, the pathophysiological
Ningning He et al.
Molecular cancer therapeutics, 13(10), 2463-2473 (2014-08-15)
The recent proliferation of data on large collections of well-characterized cancer cell lines linked to therapeutic drug responses has made it possible to identify lineage- and mutation-specific transcriptional markers that can help optimize implementation of anticancer agents. Here, we leverage
Els Pardon et al.
Nature protocols, 9(3), 674-693 (2014-03-01)
There is growing interest in using antibodies as auxiliary tools to crystallize proteins. Here we describe a general protocol for the generation of Nanobodies to be used as crystallization chaperones for the structural investigation of diverse conformational states of flexible
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