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Changgeng Liu et al.
Environmental science & technology, 46(24), 13262-13269 (2012-11-23)
Methoxyphenols, tracers for wood smoke, are emitted into the atmosphere in large quantities, but their chemical degradation in the atmosphere has not been well characterized. In this study, heterogeneous kinetics of particulate syringaldehyde (SA), vanillic acid (VA), and coniferyl aldehyde
Epicatechin, procyanidins, and phenolic microbial metabolites after cocoa intake in humans and rats.
Mireia Urpi-Sarda et al.
Analytical and bioanalytical chemistry, 394(6), 1545-1556 (2009-04-01)
Proanthocyanidins, flavonoids exhibiting cardiovascular protection, constitute a major fraction of the flavonoid ingested in the human diet. Although they are poorly absorbed, they are metabolized by the intestinal microbiota into various phenolic acids. An analytical method, based on an optimized
Margreet R Olthof et al.
The Journal of nutrition, 133(6), 1806-1814 (2003-05-29)
Dietary phenols are antioxidants, and their consumption might contribute to the prevention of cardiovascular disease. Coffee and tea are major dietary sources of phenols. Dietary phenols are metabolized extensively in the body. Lack of quantitative data on their metabolites hinders
Sadaf Naeem et al.
Bioorganic & medicinal chemistry, 20(3), 1251-1258 (2012-01-21)
Data on phytochemical constituents of plants commonly used in traditional Indonesian medicine have been compiled as a computer database. This database (the Indonesian Herbal constituents database, IHD) currently contains details on ∼1,000 compounds found in 33 different plants. For each
Michel Schroyen et al.
Bioresource technology, 192, 696-702 (2015-06-22)
Pretreatment of lignocellulosic biomass is necessary to enhance the hydrolysis, which is the rate-limiting step in biogas production. Laccase and versatile peroxidase are enzymes known to degrade lignin. Therefore, the impact of enzymatic pretreatment was studied on a variety of
Li Liu et al.
Bioorganic & medicinal chemistry letters, 22(1), 154-163 (2011-12-06)
The binding between the estrogen receptor α (ER-α) and a variety of compounds in traditional Chinese formulae, Si-Wu-Tang (SWT) series decoctions, was studied using a stably-transfected human breast cancer cell line (MVLN). In 38 compounds tested from SWT series decoctions
Jian-Feng Tang et al.
Bioorganic & medicinal chemistry, 20(14), 4226-4236 (2012-06-26)
In present study, a series of novel 1,3,4-oxadiazole derivatives have been designed, synthesized and purified. All of these compounds are reported for the first time, the chemical structures of these compounds were confirmed by means of (1)H NMR, ESI-MS and
Miriam Cristina Díaz-García et al.
Journal of the science of food and agriculture, 95(6), 1283-1293 (2014-07-22)
Anthocyanins and other polyphenols from flowers and bracts of Thymus sp. are studied. An anthocyanin-rich food colourant with interesting high antioxidant activity from Thymus moroderi has been obtained, and applied to colour foods. Anthocyanins and other polyphenols from T. moroderi
Laurent Y Rios et al.
The American journal of clinical nutrition, 77(4), 912-918 (2003-03-29)
Proanthocyanidins, the most abundant polyphenols in chocolate, are not depolymerized in the stomach and reach the small intestine intact, where they are hardly absorbed because of their high molecular weight. In vitro and in vivo studies using pure compounds as
Delphine Lamoral-Theys et al.
Bioorganic & medicinal chemistry, 18(11), 3823-3833 (2010-05-15)
A series of 33 novel divanillates and trivanillates were synthesized and found to possess promising cytostatic rather than cytotoxic properties. Several compounds under study decreased by >50% the activity of Aurora A, B, and C, and WEE1 kinase activity at
Fate of microbial metabolites of dietary polyphenols in rats: is the brain their target destination?
Mattia Gasperotti et al.
ACS chemical neuroscience, 6(8), 1341-1352 (2015-04-22)
Different polyphenol compounds are ingested when consuming a serving of fruits rich in polyphenols, spanning from one-phenol hydroxybenzoic acid to more complex polymeric compounds. Only a minor quantity of the polyphenols (5-10%) is absorbed. The remainder reaches the colon and
Wen Ding et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(7), 916-919 (2012-07-17)
To study the dissolution rate of active components of different extracting solvents of Danggui Chishao drug pair. The dissolution rates of phenolic acids (ferulic acid, vanillic acid and gallic acid), monoterpenes (gallic acid, peoniflorin, albiflorin, hydroxypeoniflorin and galloylpaeoniflorin) and phthalates
Organoleptic Characteristics of Flavor Materials
Mosciano, G.
Perfumer & Flavorist, 30, 42-42 (2005)
Belén Max et al.
Applied biochemistry and biotechnology, 168(8), 2268-2284 (2012-10-19)
Debaryomyces hansenii NRRL Y-7426 metabolised ferulic acid into different phenolic compounds using a factorial design where glucose concentration (in the range of 1-20 g/L), peptone concentration (2-20 g/L) and yeast extract concentration (0.2-10 g/L) were the independent variables. The interrelationship between dependent and
Jessica L di Gesso et al.
Molecular nutrition & food research, 59(6), 1143-1154 (2015-03-25)
Flavonoids are generally studied in vitro, in isolation, and as unmetabolized precursor structures. However, in the habitual diet, multiple flavonoids are consumed together and found present in the circulation as complex mixtures of metabolites. Using a unique study design, we
Chao-Bin Xue et al.
Bioorganic & medicinal chemistry, 15(5), 2006-2015 (2007-01-30)
Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-quinones. Inhibition of PO may provide a basis for novel environmentally friendly
Ki Hyun Kim et al.
Bioorganic & medicinal chemistry letters, 21(8), 2270-2273 (2011-03-23)
A bioassay-guided fractionation and chemical investigation of the trunk of Berberis koreana resulted in the isolation and identification of a new sesquilignan, named berbikonol (1), along with fourteen known lignan derivatives (2-15) and a new phenolic compound, named berfussinol (16)
Muhammed Alzweiri et al.
Biomedical chromatography : BMC, 27(9), 1157-1161 (2013-04-23)
α-3 carbonic anhydrase isozyme (CAIII) is the most abundant protein in adipocytes and considered insensitive to sulfonamide inhibitors. It was reported recently that the knock-down of CAIII is attributed with controlling lipogenesis. Thus inhibition of this target may lead to
The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells.
Woo-Suk Choi et al.
Cellular immunology, 280(2), 164-170 (2013-02-13)
Veratric acid, a simple benzoic acid derived from plants and fruits, has been reported to have anti-oxidant, anti-inflammation, and blood pressure-lowering effects. This study was designed to evaluate the inhibitory effects of veratric acid on nitric oxide (NO) production in
Spencer M Steinberg
Environmental monitoring and assessment, 185(5), 3749-3757 (2012-08-15)
A new method for determination of hydrogen peroxide (H2O2) is described. H2O2 reacts with iodide in the presence of ammonium molybdate and vanillic acid resulting in the formation of iodovanillic acid which is quantified by reversed-phase high-performance liquid chromatography (HPLC)
Ting Tang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(9), 1237-1240 (2012-07-19)
Twelve compounds were separated from stems of Dysoxylum laxiracemosum and their structures were identified by spectrum analysis as shoreic acid (1), cabraleahydroxylactone (2), cabralealactone (3), cinchonain (5), catechin (6), scopoletin (7), vanillic acid (8), p-hydroxybenzoic acid (9), docosanol (10), beta-sitosterol
Janique Vandal et al.
Pharmaceutical biology, 53(6), 800-806 (2015-02-24)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MDR
Wan Cao et al.
Electrophoresis, 36(7-8), 1055-1063 (2015-02-03)
This report describes the use of surfactant-coated graphitized multiwalled carbon nanotubes (SC-GMWNTs) as a novel pseudostationary phase in CE with diode array detection for the determination of phenolic acids and tanshinones in herbal and urine samples. Several parameters influencing the
Jae B Park
Journal of chromatographic science, 52(5), 436-441 (2013-05-29)
Amkamide is a phenolic amide whose analogues were recently reported to have potent mitochondria protective activity, although their bioavailability is still unknown. Therefore, in this study, amkamide was synthesized and confirmed by nuclear magnetic resonance, and a high-performance liquid chromatography
Mohamed A Farag et al.
Chemistry & biodiversity, 12(6), 955-962 (2015-06-18)
Bacterial wilts of potato, tomato, pepper, and or eggplant caused by Ralstonia solanacearum are among the most serious plant diseases worldwide. In this study, the issue of developing bactericidal agents from natural sources against R. solanacearum derived from plant extracts
Andreas R Rechner et al.
Free radical research, 36(11), 1229-1241 (2003-02-21)
Berry extracts rich in anthocyanins have been linked to protective effects including the modulation of age-related neurological dysfunction and the improvement of the resistance of red blood cells against oxidative stress in vitro. In this study the bioavailability, metabolism and
Muhammed Alzweiri et al.
Journal of enzyme inhibition and medicinal chemistry, 30(3), 420-429 (2014-07-30)
An HPLC-size exclusion method was developed as an assay method to evaluate the binding of tested compounds with carbonic anhydrase III (CAIII) enzyme. Inhibition of CAIII by a group of benzoic acid analogues was characterized by vacancy (negative) peak intensity
Shuang Song et al.
Journal of natural products, 73(2), 177-184 (2010-01-23)
Eleven new diglycosides, erycibosides A-K (1-11), four new chlorogenic acid derivatives (14-17), and a new bis-coumarin (18), together with 21 known compounds, have been isolated from an EtOH extract of the roots and stems of Erycibe hainanesis. Their structures were
Nurcan Değirmencioğlu et al.
Food chemistry, 194, 587-594 (2015-10-17)
In this study, the changes in phenolic composition, total phenolic content, and antioxidant capacity of tarhanas supplemented with oat flour (OF) at the levels of 20-100% (w/w) after three drying treatments (sun-, oven-, and microwave drying) were investigated. A total
Wai Mun Loke et al.
The Journal of nutrition, 139(12), 2309-2314 (2009-10-09)
Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumption. Valid biomarkers of flavonoid intake may be useful for estimating exposure in a range of
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