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Britta Haenisch et al.
Fundamental & clinical pharmacology, 24(6), 729-739 (2009-12-25)
Oxymetazoline and xylometazoline are both used as nasal mucosa decongesting α-adrenoceptor agonists during a common cold. However, it is largely unknown which of the six α-adrenoceptor subtypes are actually present in human nasal mucosa, which are activated by the two
B Strandell et al.
International journal of clinical pharmacology and therapeutics, 47(12), 744-751 (2009-12-04)
Combination of xylometazoline and ipratropium in a nasal spray provides fast, effective symptomatic relief of nasal congestion and rhinorrhea in adults with common cold. To gather data in a non-prescription setting regarding the safety, pattern of use, patients' general assessment
[Nasal decongestants and eye drops: keep out of children's reach!].
Sarah Poulin-Chartrand
Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec, 10(2), 63-63 (2013-04-02)
Görkem Eskiizmir et al.
European journal of clinical pharmacology, 67(1), 19-23 (2010-11-12)
Oxymetazoline and xylometazoline are locally effective and direct acting drugs that relieve nasal congestion. The aim of this study was to objectively determine and compare the decongestive effects of oxymetazoline and xylometazoline in healthy subjects. The study population comprised thirty
Gerd Fabian Volk et al.
Archives of otolaryngology--head & neck surgery, 136(10), 1015-1019 (2010-10-20)
To identify objective criteria predicting the success of diode laser-assisted turbinoplasty. Prospective before-and-after trial with follow-up of 8 weeks. Outpatient department of a tertiary referral center. Forty-one patients with nasal obstruction caused by hyperplastic inferior nasal turbinates. Active anterior rhinomanometry
I T Bognar et al.
The Journal of pharmacology and experimental therapeutics, 254(2), 702-710 (1990-08-01)
Rat hearts were isolated with the vagus nerves intact and perfused, and the neuronal acetylcholine stores were pulse labeled with [14C]choline. The overflow of [14C]choline/acetylcholine evoked by extrinsic vagus nerve stimulation (3 Hz and 720 pulses or 10 Hz and
Xinli Zhou et al.
Hypertension (Dallas, Tex. : 1979), 55(4), 880-888 (2010-02-24)
Insulin resistance is associated with obesity and may be accompanied by left ventricular diastolic dysfunction and myocardial remodeling. Decreased insulin metabolic signaling and increased oxidative stress may promote these maladaptive changes. In this context, the beta-blocker nebivolol has been reported
["Of snakes and crocodiles": central side effects of nose drops and facts about rhinitis medicamentosa].
Jens Bielenberg
Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 30(10), 406-408 (2011-10-28)
A M Zicari et al.
International journal of pediatric otorhinolaryngology, 76(3), 352-356 (2012-01-03)
Nasal respiratory obstruction is a very common otolaryngologic problem, often caused by adenoid hypertrophy (AH). Nasal fiberoptic endoscopy (NFE) represents the gold standard method to diagnose AH. Rhinomanometry represents a valid diagnostic support. The aim of our study was to
S Staar et al.
Anaesthesia, 68(5), 467-471 (2013-03-14)
We assessed the effect of modifying standard Magill forceps on the laryngeal introduction of an Eschmann stylet during nasotracheal intubations with three indirect laryngoscopes (Airtraq™, C-MAC(®) or GlideScope(®)) in patients with predicted difficult intubation. We allocated 50 participants to each
Hypertensive crisis and end-organ damage induced by over-the-counter nasal decongestant abuse.
Ian Buysschaert et al.
European heart journal, 32(24), 3114-3114 (2011-06-30)
Paradoxical increase in nasal airway resistance following a topical nasal decongestant spray.
N M Doddi et al.
Rhinology, 49(1), 127-127 (2011-04-07)
Justin Cheung et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 24(5), 317-321 (2010-05-21)
The optimal topical anesthesia regimen for unsedated transnasal endoscopy is unknown. The addition of a nasal decongestant, such as xylometazoline (X), to a topical anesthestic may improve patient comfort. To determine the effectiveness of lidocaine (L) versus L plus X
Helle L Thulesius et al.
Rhinology, 49(1), 46-52 (2011-04-07)
Rhinomanometry before and after decongestion distinguishes a nasal airway organic stenosis from congestion of nasal mucosa in patients with nasal stuffiness. Together with rhinoscopy and patient history, it is used to decide if nasal surgery would benefit the patient. Rhinomanometry
Z A El-Seify et al.
British journal of anaesthesia, 105(4), 501-505 (2010-08-05)
Epistaxis is the most common complication encountered during nasotracheal intubation (NTI) in children. The aim of this study was to test the efficacy of prophylactic intranasal admixture of xylometazoline and local anaesthetic gel in reducing epistaxis after NTI in children.
Ronald Eccles et al.
Current medical research and opinion, 26(4), 889-899 (2010-02-16)
Common cold is one of the most prevalent conditions that family doctors encounter. One of the first symptoms to occur is nasal congestion, which can have a negative impact on daily life and prompts many patients to seek treatment for
Catherine E Rennie et al.
International forum of allergy & rhinology, 1(2), 128-135 (2012-01-31)
This study quantifies the time-varying flow rate during inspiration at rest and in sniffing, both predecongestion and postdecongestion. It aims to provide a better understanding of nasal airflow mechanics, for application to the physiological modeling of nasal respiration and to
Prasun Mishra et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(1), 117-121 (2012-03-20)
During nasal endoscopy it is essential to have proper visualization of structures with minimal discomfort to patient and surgeon. For this it is essential that the nose is well prepared before the procedure. The main objective of the study is
Xylometazoline pretreatment reduces nasotracheal intubation-related epistaxis in paediatric dental surgery.
J L Tong
British journal of anaesthesia, 106(2), 279-279 (2011-01-15)
Katarzyna Korzeniowska et al.
Przeglad lekarski, 69(10), 1168-1169 (2013-02-21)
The article describes the case of 34-years old man, who has used nasal drops with xylomethazoline for three years. Health consequence of uncontrolled use of the drops and treatment were prescribed. Described problem confirms the need of physicians and pharmacists
Daniela Leupold et al.
The neurologist, 17(1), 41-43 (2010-12-31)
substance abuse is an important cause of ischemic stroke in the young. This includes over-the-counter dietary supplements and cough and cold remedies, which were reported to be an independent risk factor for hemorrhagic stroke. this article describes a young male
Nigel K F Koo Ng et al.
Orbit (Amsterdam, Netherlands), 29(6), 346-347 (2010-12-17)
We report a case of unilateral mydriasis following nasal electrocautery presumed to be the result of retrograde flow of adrenaline and/or xylometazoline hydrochloride (Otrivine) through the nasolacrimal duct into the eye. We review the literature and highlight the importance of
Neil K Chadha et al.
JAMA otolaryngology-- head & neck surgery, 139(12), 1301-1305 (2013-10-26)
To our knowledge, the present study is the first double-blind, randomized, placebo-controlled trial in children to compare nasal preparation sprays administered before flexible nasendoscopy with placebo. To compare the degree of pain experienced by children undergoing flexible nasendoscopy after 1
Jiaoping Mi et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 837-841 (2011-12-17)
This study prospectively examined the intranasal distribution of nasal spray after nasal septal correction and decongestant administration. A cohort of 20 patients was assessed for the distribution of nasal spray before and after nasal septum surgery. Sprays were dyed and
Comments on: Central serous chorioretinopathy after dacryocystorhinostomy operation on the same side.
Parthasarathi Roy
Indian journal of ophthalmology, 58(2), 167-168 (2010-03-03)
Inge Elly Kiemle Trindade et al.
Brazilian journal of otorhinolaryngology, 79(5), 575-581 (2013-10-22)
Nasal septum deviation (SD) and turbinate hypertrophy (TH) increase the resistance to respiratory airflow and may impair nasal patency. To characterize the nasal geometry of individuals with nasal obstruction secondary to SD and/or TH by means of acoustic rhinometry. This
Sami Bercin et al.
Acta oto-laryngologica, 129(11), 1257-1261 (2009-10-30)
This study revealed that the nasal topical drops, which could be purchased without a proper prescription, should not be used randomly and non-selectively. To investigate the effect of nasal drops and sprays on the nasal air flow and mucociliary transport
H Sakuta et al.
European journal of pharmacology, 259(3), 223-231 (1994-07-11)
The effects of imidazoline and imidazolidine derivatives on glibenclamide-sensitive K+ currents induced by the novel K+ channel opener, Y-26763 ((+)-(3S,4R)-4-(N-acetyl-N-benzyloxyamino)-6-cyano-3,4-dihydro-2,2 -dimethyl-2H-1-benzopyran-3-ol), were investigated in voltage-clamped follicle-enclosed Xenopus oocytes. Of 14 imidazoline derivatives and seven imidazolidine derivatives tested, phenotalmine, (-)-cibenzoline, (+)-cibenzoline
A M Zicari et al.
European review for medical and pharmacological sciences, 17(21), 2962-2967 (2013-11-21)
Adenoid hypertrophy (AH) is a very common problem in children. Nasal Fiberoptic Endoscopy (NFE) represents the gold standard method to diagnose AH. Rhinomanometry represents a valid diagnostic support. The aim of our study was to analyze the grade of nasal
Alvaro C Laga et al.
The American journal of pathology, 176(2), 903-913 (2010-01-01)
SOX2 is a gene located on chromosome 3q26.33 that encodes a transcription factor important to maintenance of embryonic neural crest stem cell pluripotency. We have identified rare SOX2-immunoreactive cells in normal human skin at or near the established stem cell
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